French researchers recently discovered that certain diabetes medicines known as diuretics may raise the risk for amputation. This conclusion was obtained after an analysis of approximately 1,500 patients with type 2 diabetes. After seven years, 13% of participants who used diuretics had gone through an amputation or other procedure of the lower leg. This was compared to 7% of those who didn’t take diuretics. Likewise, taking diuretics was found to have a 75% increased risk of having an amputation or a bypass or angioplasty.
Based on these findings, researchers from Bichat Hospital in Paris warn that diuretics be used cautiously in patients with type 2 diabetes. However, further studies are needed to confirm these results.
These findings were presented at the European Association for the Study of Diabetes meeting on October 1, 2018.