New Type 2 Drugs Change Treatment Decisions

Metformin, the cornerstone in treating type 2 diabetes, saw an increase in usage among type 2s from 23 percent of that population in 1997 to 53 percent in 2012. But that increase has since plateaued due to the introduction of additional drugs that target insulin secretion and glucose regulation. DPP-4 inhibitors, such as Januvia and Onglyza, now account for 21 percent of treatments. Long-acting insulins,

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Common Diabetes Drugs May Carry Risk, Study Suggests

When it comes to the treatment of type 2 diabetes, metformin may be a safer choice than sulfonylureas, according to the results of a new study. In the study, conducted in Great Britain, people who used sulfonylureas as an initial way to control their blood glucose levels had a higher risk of death than those taking metformin. Sulfonylureas encourage increased production of insulin by the

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ACP Guidelines Say Metformin Is the Best Starter Drug for Type 2s

The latest clinical guidelines for treating type 2 diabetes from the American College of Physicians (ACP) indicate that when diet, exercise, and weight loss fail to control blood sugar levels in early type 2 patients, physicians should prescribe metformin as the first drug therapy. The ACP recommends that metformin be prescribed initially as a stand-alone monotherapy. As the disease progresses and metformin’s initial efficacy begins

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