Angiotensin-converting enzyme (ACE) inhibitors have always been a popular therapy for diabetics trying to keep their blood pressure in line. However, researchers now say that if you are pregnant and suffer from high blood pressure, you should stay away from ACE inhibitors during the first trimester.
Previously, ACE inhibitors have not been recommended during the second and third trimesters of pregnancy. This study was the first linked to adverse fetal outcomes.
—New England Journal of Medicine, June 8, 2006