Super-Tight Control of Blood Sugar After Kidney Transplant May Be Counterproductive


By: Mari Gold

To see if tightly controlling blood sugar provides improved results in patients who received a kidney transplant, a group of diabetic post-transplant patients were followed for three days. A subset of the randomly assigned group had their blood glucose kept in tight range with IV insulin, while a control group received insulin as they ordinarily would, via injections.

According to Kathie L. Hermayer, MD, and colleagues at the Medical University of South Carolina in Charleston, who reported on the study in The Journal of Clinical Endocrinology & Metabolism, intensive management via the IV insulin raised the risk of graft rejection to 20 percent, compared with 4 percent among patients in the control group. “Intensive therapy may be harmful for rejection,” Hermayer said, adding that “”Managing glucose levels in the renal transplant patient is challenging…due to immunosuppressive agents and corticosteroid dosing.”

Source: The Journal of Clinical Endocrinology & Metabolism



Diabetes Health Medical Disclaimer
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.