Type 1 diabetics who keep their HDL (good) cholesterol levels elevated may be protecting themselves from the development of albuminuria. Researchers at the Northwestern University Feinberg School of Medicine in Chicago say that it remains to be determined whether the elevated HDL is the cause of the protective effect.
The researchers analyzed the lipid profiles of 107 patients with type 1 of 20 years’ duration. Forty-two of the patients had albuminuria (28 microalbuminuria and 14 macroalbuminuria) and 65 did not. The results showed that for every 21-mg/dl increase in HDL cholesterol, patients are approximately half as likely to have albuminuria.
—Diabetes Care, January 2006
Having more than the normal amount of albumin in the urine. Albumin is the predominant protein in human blood and it is the key to the regulation of the osmotic pressure of blood.