Although severe hypoglycemia is a definite problem for children and adolescents with type 1 diabetes, newer therapies may improve control without increasing the risk of severe hypoglycemia.
In a study, 1,335 Australian children with type 1 diabetes were observed for 10 years. During this time, 944 severe hypoglycemic events were recorded. Severe hypoglycemia increased by 29 percent for the first five years but leveled off over the last five years.
The overall average A1C significantly decreased during the follow-up period. Risk of severe hypoglycemia was associated with lower A1C, younger age, higher insulin dose, male sex and lower parental socioeconomic status.
Only insulin pump treatment was associated with reduced rates of severe hypoglycemia.
—Diabetes Care, October 2004