Diabetes Health in The News: Oral Insulin Doesn’t Prevent Type 1 Diabetes

A recent study found that providing a 7.5mg dose of oral insulin to people without diabetes did not prevent type 1 diabetes development. These results were first reported at the June 2017 meeting of the American Diabetes Association.

The researchers used the data from 389 people, almost 58% of whom had a sibling living with diabetes. Participants were mostly adolescents and children with normal blood glucose, but they also had at least two islet autoantibodies. This indicated they would likely develop type 1 diabetes in the future.

Participants were randomized into two groups: one group received a placebo and the other received 7.5 mg of oral insulin each day. At follow-up nearly three years later, there was no significant difference in type 1 diabetes diagnosis among the two groups.  

These findings were published in the Journal of the American Medical Association on November 21, 2017.

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