Austrian researchers have recently discovered that certain genetic information could be significant predictors of cardiovascular events in coronary artery disease patients who also have type 2 diabetes. Specifically, this genetic information comes from single nu cleotide poly morphisms found at the Niemann-Pick C-like 1 (NPC1L1) gene locus. NPC1L1 plays a role in the absorption of dietary cholesterol.
These findings came from studying 943 patients who went through coronary angiography. About 240 of these patients had type 2 diabetes. After a follow-up of 3.5 years, roughly 23% of the diabetic patients had experienced their first vascular event. This was compared to only 18% of the entire group that experienced their first vascular event within the same time period.
These findings were published in the Endocrinology Advisor on April 14, 2016.