TZD Beats Sulfonylurea in Artery Wall Competition

5249

By: Linda von Wartburg

Thinner artery walls are a good thing, because thicker ones indicateatherosclerosis and an increased risk of heart attack. In a studypublished in the December 2006 Journal of the American MedicalAssociation, pioglitazone (Actos, a thiazolidinedione) was comparedto glimepiride (a sulfonylurea) with regard to carotid arterythickness.

For a period of 18 months, 462 patients with type 2diabetes were given one or the other. In the end, the thickness ofthe artery in the glimepiride group increased by a tiny amount,0.012 millimeters. In the pioglitazone group, average thicknessfell by an even tinier amount, 0.001 millimeters.

Source: JAMA

Comments

comments

Diabetes Health Medical Disclaimer
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.