Network to Focus on Type 1 Prevention


By: Jan Chait

Fourteen entities have joined forces to form Type 1 Diabetes TrialNet, a collaborative effort to test new approaches to understanding, preventing and treating type 1 diabetes. Recruitment for the first trials is expected to begin in early 2003.

Prevention trials will attempt to stop or delay the destruction of insulin-producing beta cells in people at risk for type 1 diabetes. Treatment trials will try to preserve remaining beta cells in those with new-onset type 1 diabetes.

“TrialNet will expedite the application of discoveries in basic research to therapies that benefit people with type 1 diabetes and those at risk,” says Jay Skyler, MD, of the University of Miami.

Skyler, who is the study chair for TrialNet, oversaw the Diabetes Prevention Trial Type 1 (DPT-1). DPT-1 had two components: a low-dose insulin injection trial that ended in 2001 after discovering that the injections failed to prevent type 1 diabetes; and an oral insulin trial, which will become part of the new TrialNet.

“Mounting individual trials for prevention of type 1 diabetes is a challenging, costly endeavor,” says Allen Spiegel, MD, director of the National Institute of Diabetes and Digestive and Kidney Diseases, which leads the initiative. “This network provides a stable, efficient, cost-effective system for identifying people at risk for type 1 diabetes and testing the ability of promising new agents to prevent the disease.”

For more information about TrialNet, call (800) 425-8361.



Diabetes Health Medical Disclaimer
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Opinions expressed here are the opinions of writers, contributors, and commentators, and are not necessarily those of Diabetes Health. Never disregard professional medical advice or delay seeking medical treatment because of something you have read on or accessed through this website.