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Latest Research Articles
Diabetes and Alzheimer’s Disease
Oct 29, 2009
While the relationship between Alzheimer's and diabetes is far from clear, there does seem to be an interesting connection. And that connection just became a little more complicated according to a French study published in the October 27th issue of the journal Neurology.
Diabetes is thought to increase the risk of developing Alzheimer's, possibly because of vascular damage in the brain that mimics the dementia seen with Alzheimer's. But once patients display symptoms of the disease, the current study suggests that the progression is slower than in people without diabetes. The study was supported by INSERM the French National Institute for Health and Medical Research.
Cognitive function was evaluated in 608 patients with a probable diagnosis of Alzheimer's. "Probable" diagnosis simply means that each patient met the criteria for having the disease in terms of memory impairment, but researchers did not have access to a sample of brain tissue that is necessary to confirm the diagnosis.
Patients were tested using the Mini-Mental State Examination (MMSE) twice a year, for four years. Ten percent of the patients studied had diabetes, and after adjusting for sex, age, education, severity of dementia, medication for dementia, and heart disease, it was determined that there was no difference between groups at the onset of testing, but a significantly slower rate of progression.
One complication may be that the medications used to help control blood sugar have a protective effect on the brain in terms of cognitive decline, as suggested by an article on the link between diabetes and Alzheimer's on the Mayo Clinic website.
http://www.mayoclinic.com/health/diabetes-and-alzheimers/AZ00050
http://www.nlm.nih.gov/medlineplus/news/fullstory_91066.html
Categories: Research, Type 2 Issues
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