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Diabetes and Adoption
Rachel and her husband chose to adopt a baby instead of meeting the challenges of handling a high risk pregnancy and Rachel’s type 1 diabetes at the same time. She shares their thought process and ultimate happy ending about the decision to bring a child into their lives.
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Chris Matthews Makes Time for Diabetes
Hosting Hardball on MSNBC and The Chris Matthews Show keep Chris Matthews working long hours. But Matthews got a lesson in priorities and made some life changes when he was diagnosed with type 2.
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A Chihuahua with Diabetes
Olivia and her dog both have diabetes and today they comfort and encourage each other through the rigors of dealing with the disease. Plus, find out what it means when your domestic pet is diagnosed with diabetes.
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Smoking and Diabetes
Smoking has severe effects on your diabetes and your health. Learn why diabetes and smoking are an especially bad combination and get some tips from the experts on how to quit.
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Continuous Glucose Monitors
CGM is a relatively new technology, but the information it provides is invaluable. Find out what CGM offers and whether it could help you.
The must-have resource for physicians, educators and medical professionals who focus on the treatment of diabetes.
Finally! A fresh take on the “professional” journal. Each bi-monthly issue cuts through the jargon and presents the most important information you need to enhance your practice and assist your patients.
Each bi-monthly issue of Diabetes Health Professional is a self-contained handbook covering products, educational resources and the latest diabetes research, complimented by balanced editorial focused on medical news, drug prescription information, clinical practice recommendations and changing treatment options.
Each quarter we send you the latest, most updated research guides, product guides and educational resource guides available for you and your patients.
Each week the Diabetes Health E-Newsletter delivers links to the very latest in news, reviews, blogs and videos from Diabetes Health direct to your inbox.
As a subscriber you'll get access to the amazing Diabetes Health Digital Advantage™ so you can read the current issue of Diabetes Health magazine online wherever you are!
Latest Research Articles
The findings suggest that the struggle to prevent and cure type 1 may have found two powerful weapons that will not require years of research or large outlays of money to produce.
Anti-Cancer Drugs in Lab Mice Trials Prevent or Reverse Type 1
Researchers at the University of California, San Francisco, have found that two drugs used to treat cancer can prevent or cure type 1 diabetes in mice.
The drugs, sunitinib (marketed as Sutent) and imatinib (marketed as Gleevec), prevented the development of type 1 in mice specially bred to have a predisposition to acquiring the disease.
Of the already diabetic mice that received imatinib, 80 percent went into remission. And 80 percent of those that went into remission experienced a total cure-a cure rate of 64 percent.
The findings suggest that the struggle to prevent and cure type 1 may have found two powerful weapons that will not require years of research or large outlays of money to produce. Even better, UCSF researchers say that they hope to begin using the drugs in human trials within a year.
The UCSF research team was looking into the cancer drugs because they inhibit some of the enzymes that are associated with cell growth and proliferation. Scientists think the enzymes, called tyrosine kinases, are involved in almost every aspect of the immune system, from benign signaling that summons T and B cells for defense to misfirings that create inflammation that often leads to tissue damage.
Because type 1 is an autoimmune disease, the team wondered if the subset of tyrosine kinases controlled by the cancer drugs might be the same enzymes that create pancreatic inflammation in people with diabetes.
What they found surprised them. The drugs' effectiveness seemed to come from their ability to block a tyrosine kinase that has no known connection to diabetes, an enzyme called "platelet-derived growth factor receptor" (PDGFR).
In a statement UCSF released to the press, Arthur Weiss, MD, PhD, UCSF professor of rheumatology, said, "This study opens up a new area of research in the field of type 1 diabetes and, importantly, opens up exciting opportunities for developing new therapies to treat this disease and other autoimmune diseases."
In the same release, Jeffrey Bluestone, PhD, director of the Diabetes Center at UCSF and an expert in autoimmunity, said, "There are very few drugs to treat type 1 diabetes, especially after disease onset, so this benefit, with a drug already proven to be safe and effective in cancer patients, is very promising.
"The fact that the treated mice maintained normal blood glucose levels for some time after the drug treatment was stopped suggests that imatinib and sunitinib may be ‘reprogramming' their immune systems in a permanent way.
Categories: Medications Research, Research, Type 1 Issues
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