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Print | Email | Comments (6)

Letter of the Week: Does DH's Left Hand Know What Its Right Hand is Doing?

2 April 2008
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Editor:

What a disconnect and what a disappointment!  On page 32 of your February/March issue there is a warning that Byetta can cause acute pancreatitis, and then on page 36 there is an interview with a representative of Amylin Pharmaceuticals, which makes Byetta, extolling its virtues in an interview with Scott King. I hope your magazine isn't bought off by a paid ad for a medication that can cause serious side effects. I expect better from Diabetes Health.

Marcyl Seidscher

San Mateo, CA

(Editor’s Reply: Marcyl, thank you for your attentive reading. We hope you’ll see that we did not do a disconnect in covering both good and bad aspects of Byetta. The truth is that Byetta has been closely connected with a few cases (30) of pancreatitis, and we duly reported it. We made no attempt to soft-pedal or hide that news.

But the truth also is that Byetta, in a great number of cases (thousands) has produced some astonishing results with lowered A1c’s, and notable weight loss and appetite control. Investment expert David Kliff, highly respected for his forthright, play-no-favorites advice, recently said, “When you keep in mind how rare even 30 reported cases are in comparison with the number of people who are taking Byetta, this is a non-issue. There are more than 700,000 patients using Byetta and 30 reports of pancreatitis. That’s 0.00428 percent, or 1 case per 23,364 patients. That’s rare.”

We printed reports on both aspects of Byetta because we know that printing only negative reports about the drug would be just as biased as printing only good news about it. If we could be bought off by an ad, we would have never run the article you read on page 32.  We want to thank you for holding us to a high standard, and hope that this will assure you that we hold ourselves to it, too.)


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Posted by anonymous on 5 April 2008

My sister was put on Byetta in spite of the fact that she has had two operations for bowel obstuction. Her doctor refused to take her off of it as she was "getting her weight down", not her blood sugars tho. When she became very ill, even her doctor could not believe how bad she looked when she went in, all her family and friends who saw her thought she looked like death was coming, after the took her off the Byetta, and she improved, he ended up dismissing her as a patient. Not sure why, she feels it was because she had told him several times how bad she felt.
It may be a good med for a lot of people, but those who have intestinal problems should not be on it, and a lot of them do not know that.

Posted by anonymous on 5 April 2008

Excellent and reassuring reply from the Editor.

Posted by anonymous on 5 April 2008

As a diabetes educator and type 1 for 30+ years, Byetta is a godsend to 99% of patients who use it.

The astounding results in decreased appetite, no longer obsessing about food, the fear of long-term complications because of elevated A1c's, have improved the quality of life for 100's of thousands of those who suffer with this comples disease process.

To make a sweeping judgement based upon the rarety of the acute pancreatitis as it is well justified in the Editor's reply.

Please do not throw out the baby with the bath water!

Just yesterday a man who had just started Byetta one month ago had reduced his A1c from 8.8% to 7.4% in one month and had a 10# weight loss. He was so grateful for how he felt, when he learned his new drug insurance plan would not pay for this new prescription, he paid $280.00 out of pocket because he did not want to live without it.

Posted by kathyw on 6 April 2008

I've been on Byetta for one year now with no outward signs of pancreatis, however I agree with the writer regarding your magazines two articles. Studies with 25, 50, or 75 people never seem to be an accurate test of a product. I usually disregard any such studies and maybe you should consider not reporting them either.

Posted by anonymous on 7 April 2008

Readers should be reminded that ALL drugs have risk of side effects, some common and some rare (such as pancreatitis). Drug manufacturers know this, and so do physicians, and thus patients are made aware of all possibilities. We know that there is always a risk of getting in a car accident every time we get in a car, but we still use this mode of transportation despite its risks. The same goes for pharmacologic management of diseases.

Posted by volleyball on 17 April 2008

I believe in limiting medications as someone will always be worse off from taking it. It usually is a small percentage but there isn't much good for 100% of the population.
Having 2 opinions in the magazine extols it's ability to give you the whole story. Makes it harder on the person who just want to be told do this or do that but makes it easier for the person making an informed decision.

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