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A1c Closer to Becoming ADAG

Linda von Wartburg
Sep 29, 2007

In August, a number of august organizations agreed to report the A1c in a new way, as a number called an A1c-derived average glucose, or ADAG.

Instead of using percentages like the A1c, the ADAG will use mg/dl's, the old familiar units that you see when testing your blood glucose with your meter.

The A1c test will be done the same way it's always been done; the only difference will be the units in which the results are reported. But until now, no one has known how to precisely convert the old percentages into the meter units. Only a few early studies had been carried out; although they did indicate a strong mathematical relationship between average glucose and A1c, they had monitored blood glucose fairly infrequently.

So researchers began an international trial to document the relationship between A1c's and average blood glucose, using frequent capillary measurements and continuous glucose monitoring. The study's not finished, but preliminary results on the first 250 subjects have shown a close correlation between A1c values at three months and average blood glucose during the same period. This relationship appeared to be the same for patients with type 1 and type 2 diabetes.

Using the previous nomenclature, the ADA had recommended that people with diabetes aim for an A1c of less than 7% and ideally below 6%. As best we can tell, it appears that using the new standards, a 7% A1c would be the equivalent of 155 mg/dl, and a value of 6% would be the equivalent of an average blood glucose value of 126 mg/dl.

Source: European Association for the Study of Diabetes (EASD) press release, September 2007


Categories: A1c Test, Professional Issues, Type 1 Issues, Type 2 Issues


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