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Diabetes and Adoption
Rachel and her husband chose to adopt a baby instead of meeting the challenges of handling a high risk pregnancy and Rachel’s type 1 diabetes at the same time. She shares their thought process and ultimate happy ending about the decision to bring a child into their lives.
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Chris Matthews Makes Time for Diabetes
Hosting Hardball on MSNBC and The Chris Matthews Show keep Chris Matthews working long hours. But Matthews got a lesson in priorities and made some life changes when he was diagnosed with type 2.
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A Chihuahua with Diabetes
Olivia and her dog both have diabetes and today they comfort and encourage each other through the rigors of dealing with the disease. Plus, find out what it means when your domestic pet is diagnosed with diabetes.
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Smoking and Diabetes
Smoking has severe effects on your diabetes and your health. Learn why diabetes and smoking are an especially bad combination and get some tips from the experts on how to quit.
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Continuous Glucose Monitors
CGM is a relatively new technology, but the information it provides is invaluable. Find out what CGM offers and whether it could help you.
The must-have resource for physicians, educators and medical professionals who focus on the treatment of diabetes.
Finally! A fresh take on the “professional” journal. Each bi-monthly issue cuts through the jargon and presents the most important information you need to enhance your practice and assist your patients.
Each bi-monthly issue of Diabetes Health Professional is a self-contained handbook covering products, educational resources and the latest diabetes research, complimented by balanced editorial focused on medical news, drug prescription information, clinical practice recommendations and changing treatment options.
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Latest Professional Issues Articles
Making Mice Fat or Thin with an Injection
Jul 31, 2007
Stressed mice get fat, according to a study out of Georgetown University Medical Center. And now they know the mechanism that does it; in fact, they can manipulate that mechanism to make the mice fat, or they can block the mechanism and keep the mice from getting fat no matter how stressed they may be.
Dr. Zofia Zukowska, who led the study, stressed out her mice for two weeks by making them stand in cold water or forcing them to face an aggressive alpha mouse. She found that the stressed mice, when fed a high fat "junk food" diet, gained twice as much fat as expected from their intake, all of it around their belly.
Not only did the stressed mice get twice as fat as non-stressed mice on the same diet, but they also showed signs of metabolic syndrome, including glucose intolerance, high blood pressure, inflamed blood vessels, and fat in their livers and muscles.
The researchers not only used stress to make the mice fat; they also discovered, and then played with, the mechanism by which stress leads to weight gain in mice. Stress activates a neurotransmitter called Neuropeptide Y (NPY) to bind to its receptor, called Neuropeptide Y Receptor (Y2R), in fat tissue, causing the fat cells to swell in both size and number and leading to apple-shaped obesity and metabolic syndrome.
By injecting mice with NPY, the researchers were able to generate fat in mice wherever they wanted it. And by injecting Y2R blocker into the mice's abdominal fat, they were able to shrink the fat accumulation by fifty percent in only two weeks and eliminate the metabolic syndrome.
Plastic surgeons, of course, are excited about eventually using an NPY injection to build fat in wrinkled lips and using a Y2R injection to melt away fat without surgery. That peculiar prospect aside, the findings should comfort those of us who are stressed out and seem to grow fat out of all proportion to the amount we eat. In addition to eating right, activities that lower stress may help get rid of that spare tire.
Source: EurekAlert
Georgetown Medical Center news release
Categories: Professional Issues, Type 2 Issues, Weight Loss
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