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Sperm Alert: Diabetes May Damage Sperm Cell DNA


Jun 11, 2007

Editor's Note: We hope to follow up this story when more is known, as many type 1 dads have beautiful, smart, and normal children.

A research study published in Human Reproduction, compared the sperm of 27 men with type 1 diabetes to the sperm of 29 men of equal age without diabetes.

The researchers, from Belfast in Northern Ireland, found that the sperm of the men with diabetes were just fine in many respects: There were just as many of them, and they were well-shaped, well-built, and vigorously moving little fellows.

When the DNA carried by the sperm was examined, however, there was much more damage to the DNA of the diabetic men: Around 52 percent of the DNA in their sperm cells was fragmented, compared to only 32 percent in the men without diabetes.

There was also a higher rate of deletions in the DNA inside their mitochondria, which are tiny power plants inside cells that contain their own separate DNA. The effect on the men's fertility was not assessed, and the mechanism by which the damage may occur is still unknown.

Sources: Reuters

Categories: Diabetes, Type 1 Issues

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Jun 11, 2007

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