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Normal C-peptide levels for a fasting test are generally considered to be anything between 0.5 nanograms (ng) per millileter (ml) and 3 ng/ml, although people who do not have diabetes may occasionally stray out of this range. The following is a range of C-peptide values in people without diabetes, as compiled by Endocrine Sciences, Inc., a California-based laboratory that conducts the test. It should be noted that, in some cases, subjects fell below the normal range of C-peptide values, but were still not found to have diabetes. The range of values may also vary according to what lab your health care practitioner uses.
Children (< 15 years old) 8:00 a.m. fasting: 0.4 to 2.2 ng/ml
Adults 8:00 a.m. fasting: 0.4 to 2.1 ng/ml
Two hours postprandial (after a meal): 1.2 to 3.4 ng/ml
Two hours post glucose load: 2.0 to 4.5 ng/ml
Although anything less than these numbers is generally an indicator of type 1 diabetes, values within the normal range can mean different things.
"Type 2s with insulin resistance could actually be making more insulin than a non-diabetic slim person," says Richard Bernstein, MD, FACE, FACN, CWS, of the Diabetes Center in Mamaroneck, New York. Values on the lower end may also indicate a honeymoon phase of type 1, when insulin production is slowing down but has not yet ground to a halt.
Bernstein also points out that even in type 1s, a positive C-peptide test should be a source of optimism.
"Of all my patients, I only have two who don't make any C-peptide, and I'm one of them," Bernstein says. He says this proves that most type 1s still produce at least some insulin and raises the possibility that therapies like beta-cell regeneration may eventually restore normal BG levels.
2 comments - 16 Apr 2008
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My daughter is 6 yrs. old and just diagnosed insulin resistant c- peptide fasting of 4.6 and was put on metformin.. It has been a long road but our pediatric endocrinologist found what 2 pediatrician said to be our fault (why she was gaining weight only eating 800 calories a day) if you feel uncomfortable with any thing they say find someone else your instincts are always right
MY C-PEPTIDE IS 1, MY A1C IS APPROXIMATELY 6.5, AND MY AVERAGE BLOOD SUGAR IS 114. I WORK OUT AND MAINTAIN MY WEIGHT, AND I TRY TO EAT A HEALTHY DIET. I AM ON INSULIN-4 UNITS EVERY NIGHT. IS THERE ANYTHING ELSE I CAN DO TO MAINTAIN MY HEALTH. ANY INFORMATION IS GREATLY APPRECIATED.
my c peptide test results was 1.4 (mg/dl).
How does this convert to (ng/ml)??
MY C-PEPTIDE IS HIGH 4.5 WHAT DOES THIS MEAN
I'M A DIABETE, I TAKE INSULIN. MY BLOOD TEST SHOWED I HAVE A 5.4 C-PEPTIDE READING, DOES THIS MEAN I COULD HAVE A TUMOR IN MY PANCREAS. THANK YOU
MY SON HAS A C-PEPTIDE OF 3.8. HE DID NOT HAVE A GLUCOSE TOLERANCE TEST. I WOULD HAVE EXPECTED THAT BOTH TESTS WOULD HAVE BEEN DONE TOGETHER. HIS IS MISSING THE DISTAL PORTION OF HIS PANCREAS. (3/4THS OF THE PANCREASE IS MISSING) ANY COMMENTS ARE APPRECIATED
I am presumably type I. 40u/day Latus + humulin at age 44. Diagnosed type I age 19. I have never been tested for c-peptide. I wonder why I haven't. Why has no one ever suggested this for me? What do you know of c-peptide therapy? Thank you for any help you can offer. Sharla
Why can't c-peptide be done on a random urine sample? Does it always have to be done on a 24hr sample or blood?
Thanks,
peter
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