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  • Diabetes and Adoption

    Rachel and her husband chose to adopt a baby instead of meeting the challenges of handling a high risk pregnancy and Rachel’s type 1 diabetes at the same time. She shares their thought process and ultimate happy ending about the decision to bring a child into their lives.

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    Hosting Hardball on MSNBC and The Chris Matthews Show keep Chris Matthews working long hours. But Matthews got a lesson in priorities and made some life changes when he was diagnosed with type 2.

  • A Chihuahua with Diabetes

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    Smoking has severe effects on your diabetes and your health. Learn why diabetes and smoking are an especially bad combination and get some tips from the experts on how to quit.

  • Continuous Glucose Monitors

    CGM is a relatively new technology, but the information it provides is invaluable. Find out what CGM offers and whether it could help you.

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Glucose Level Tests with FluidUnder the Skin

Miranda Schwartz
Nov 1, 1997

Looking for a bloodless, painless way to test for glucose levels, researchers have turned to the skin. Between the layers of skin is a fluid called dermal interstitial fluid (ISF) that, according to a report in September's Diabetes Care, contains enough glucose to be an accurate measure of BGs.

Success in previous experiments with dogs has encouraged ongoing research. In dogs, concentrations of glucose in subcutaneous fluid collected via a technique designed just for experimental settings was almost identical to plasma glucose concentration.

F. John Service, MD, PhD, Peter O'Brien, PhD, et al. report their findings from experiments with people in which they compared venous, capillary and interstitial fluid samples for glucose concentrations. They feel that the concentrations of glucose that were successfully analyzed closely reflect blood glucose levels and capillary glucose measurements.

Clinical trials are being planned for portable handheld devices that can sample and measure ISF.


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