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Diabetes and Adoption
Rachel and her husband chose to adopt a baby instead of meeting the challenges of handling a high risk pregnancy and Rachel’s type 1 diabetes at the same time. She shares their thought process and ultimate happy ending about the decision to bring a child into their lives.
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Chris Matthews Makes Time for Diabetes
Hosting Hardball on MSNBC and The Chris Matthews Show keep Chris Matthews working long hours. But Matthews got a lesson in priorities and made some life changes when he was diagnosed with type 2.
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A Chihuahua with Diabetes
Olivia and her dog both have diabetes and today they comfort and encourage each other through the rigors of dealing with the disease. Plus, find out what it means when your domestic pet is diagnosed with diabetes.
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Smoking and Diabetes
Smoking has severe effects on your diabetes and your health. Learn why diabetes and smoking are an especially bad combination and get some tips from the experts on how to quit.
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Continuous Glucose Monitors
CGM is a relatively new technology, but the information it provides is invaluable. Find out what CGM offers and whether it could help you.
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Latest Insulin Articles
More on Ultralente Insulin
A report published in the August 1992 issue of Diabetes Care predicts that the early morning high blood sugars (hyperglycemia) experienced by Type I diabetes patients could possibly be the result of their current insulin therapy. With a twice-daily dosage of combined human lente and regular insulin (HL/R) injections, blood sugar levels may rise from a lack of insulin early in the morning, when it is needed most.
Researchers from the Department of Pediatrics and Medicine at the Indiana University Medical Center, Indianapolis, compared the effects of human ultralente insulin (HUL) and human lente insulin on morning fasting blood glucose levels. The purpose of the study was to determine whether a twice-daily regimen of human ultralente insulin combined with regular insulin (HUL/R) would improve raised morning blood sugar levels and metabolic control in children with Type I diabetes.
The researchers developed a twice-daily injection regimen using HUL insulin in their study. The authors of the report note that since HUL insulin has a longer duration and a diminished peak, it would increase the amount of insulin available in the early morning hours.
Thirty-one children with Type I diabetes were selected to carry out the study. After continuing the patients on four more weeks of HL/R injections, the researchers split the group into HUL/R insulin users and HL/R insulin users. The trial lasted for twelve weeks, with each patient taking an injection once before breakfast and once before the evening meal.
After the twelve week trial, the researchers concluded that young Type I diabetes patients using twice-daily doses of human ultralente (HUL) insulin combined with regular insulin can safely improve fasting blood glucose levels and lower the magnitude of the morning glucose rise. HUL/R did not improve metabolic control.
Categories: Insulin
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