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Dietary glycemic load may predict the level of HDL cholesterol in younger people.

As sugar and other carbohydrate intake increases, the beneficial HDL (good) cholesterol level decreases. Making dietary restrictions without paying attention to a possible resulting increase in glycemic load may have an unfavorable influence on blood lipids, caution researchers in a Wisconsin study.

Correlations between blood lipids and dietary constituents were examined in 32 healthy males and females between the ages of 11 and 25. Subjects exhibited a range of LDL cholesterol values and body mass index scores. Dietary constituents were assessed from the subjects’ food diaries.

There were significant negative correlations between HDL cholesterol and glycemic load (in relation to white bread), percentage of carbohydrate, total dietary sugar, total carbohydrate and fructose. Glycemic load accounted for 21.1 percent of the variation in HDL cholesterol.

American Journal of Clinical Nutrition, February 2005

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