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Diabetes Medications Article Archives
May 2012
Researchers in Taipei, Taiwan, report that they have identified the top three drugs for reducing A1C levels in type 2 diabetes: biphasic insulin, GLP-1 analogs, and basal insulin. They hedged a little on their endorsement of GLP-1 analogs, however, by saying that although they are not decisively better at controlling A1Cs than other oral diabetes drugs, they have the advantage of helping to reduce weight without adding to the danger of hypoglycemia.
0 comments - Posted May 16, 2012
A successful experiment on mice with type 1 diabetes, which involved "reprogramming" their immune systems to stop attacks on pancreatic beta cells, may point the way to an eventual cure for the disease in humans.
0 comments - Posted May 15, 2012
With tens of millions of American facing life with type 2 diabetes and many millions more at risk of the disease, scientists are scrambling to unravel novel treatments. The latest breakthrough could come from California's Salk Institute.
0 comments - Posted May 13, 2012
Novo Nordisk's new variety of long-lasting insulin, insulin degludec, reduces low blood sugars while improving overall control, according to a pair of studies published in the prestigious journal The Lancet on April 27.
0 comments - Posted May 8, 2012
Diabetes Health recently submitted some questions to CVS Caremark Corporation regarding its "The State of the States: Adherence Report." The report compiled data from more than 50 million patients to track their level of adherence to drug prescriptions for four chronic diseases: diabetes, depression, high blood pressure, and high cholesterol.
2 comments - Posted May 4, 2012
It may be better for older people with type 2 diabetes to have less stringent A1C goals than younger type 2s, according to new guidelines from the American Diabetes Association and the European Association for the Study of Diabetes.
5 comments - Posted May 3, 2012
April 2012
On April 19, the US Food and Drug Administration issued a warning to diabetes patients not to combine the blood pressure medication aliskiren (Tekturna) with ACE inhibitors or angiotensin receptor blockers. The warning also applies to patients who have renal impairment.
2 comments - Posted Apr 30, 2012
My oldest nephew, James, has a double whammy to deal with. His aunt, yours truly, has type 1 diabetes, and so does his father. I was in the room when my sister had an ultrasound during her pregnancy with James, and I clearly remember the doctor asking her if anyone in her family had diabetes. We shared a look as she informed the doctor of my diabetes and her husband's diabetes. I know we also shared a silent prayer as the reality hit us that diabetes might be passed on to her children.
3 comments - Posted Apr 27, 2012
NeuroMetrix, Inc., a Massachusetts-based medical device company, has filed a 510(k) form with the US Food and Drug Administration for the SENSUSTM, a pain therapy device for people who suffer diabetic neuropathy. A 510(k) is a "premarket notification" of a company's intent to market a medical product. The FDA then tests the product and provides feedback to the manufacturer. Once the FDA clears the product, its maker can introduce it to the US market.
1 comment - Posted Apr 24, 2012
As we approach the summer season, our thoughts turn to barbecues, picnics, amusement parks, and road trips to the beach. It is a season of fun, but it can be hard for people with diabetes to enjoy the festivities and still maintain healthy eating habits.
1 comment - Posted Apr 23, 2012
The challenges of pregnancy are daunting on their own, but when you're diabetic, they can seem insurmountable. That's one of the reasons Cheryl Alkon wrote a book on the subject. Having type 1 diabetes herself, Alkon knew firsthand the challenges of controlling her disease during pregnancy, and of raising the kids who followed.
3 comments - Posted Apr 13, 2012
To love a diabetic is to be a doctor. It means helping her to remember her medications. It means driving her for an hour to the only 24 hour pharmacy when she's gotten the flu and can't take the Nyquil in the refrigerator. Or driving her to the hospital when the simple flu turns into bronchitis and her blood turns acidic.
37 comments - Posted Apr 12, 2012
The U.S. Food and Drug Administration says that Levemir is safe for use by pregnant women and does not increase the risk of harm to children in the womb.
1 comment - Posted Apr 4, 2012
As I listen to the news of the recent Mega Millions jackpot of over $600 million, my dreams aren't about fast cars, vast mansions, or plush vacations. My thoughts revolve around my diabetes. How awesome would it be to have the best care that money can buy?
7 comments - Posted Apr 1, 2012
March 2012
A Diabetes Health reader writes in to ask: Is there a generic alternative to Humalog insulin? If so, what is its cost compared to Humalog?
8 comments - Posted Mar 30, 2012
Readers occasionally ask us for advice about drugs they are taking. When they do, we refer their questions to a medical professional. In the question below, a Florida reader expresses concerns about the interaction of her diabetes drug with the medicines she takes for asthma.
0 comments - Posted Mar 29, 2012
Type 1 Diabetes TrialNet, an international network of researchers exploring ways to prevent and delay the progression of type 1 diabetes, has reached an important milestone: screening 100,000 people to detect who among is at risk of developing type 1 diabetes. This is a major achievement because it has helped researchers better predict who will develop diabetes and when it will require treatment. Earlier diagnosis helps patients avoid a severe, life-threatening condition called diabetic ketoacidosis.
0 comments - Posted Mar 28, 2012
The FDA has approved the start of outpatient trials of a smart phone-based monitoring device that functions as an artificial pancreas. If the device, which automatically measures blood glucose levels and adjusts them with insulin, is successful, several million type 1 patients could enjoy a whole new level of convenience.
25 comments - Posted Mar 27, 2012
It's spring break again, when thousands of people head to the beach. A lot of wonderful things come with being out and about on spring break, but if you have diabetes, there are also several things you should consider. There's going to be more traffic, fewer parking places, lots of people, an abundance of uncalculated carbohydrate sources, and longer waits for everything, to name just a few.
2 comments - Posted Mar 26, 2012
Long-term use of metformin as a weight loss aid is both safe and effective in preventing or delaying the onset of type 2 diabetes, says the Diabetes Prevention Program Research Group.
2 comments - Posted Mar 25, 2012
Do you struggle with controlling your sugar levels during exercise? When my doctor changed my exercise regimen after my heart attack, my biggest struggle was keeping my sugar levels stable. We all like to see low numbers, but no one likes the shaking associated with low blood sugar or that feeling we have for the rest of the day after our levels have fluctuated. So how low is too low before working out?
1 comment - Posted Mar 22, 2012
A little more than 25 years ago, I was diagnosed with type 1 diabetes.
6 comments - Posted Mar 21, 2012
If you are newly diagnosed with type 2 diabetes and don't take insulin, a new study says that you are likely to have better A1Cs if you have access to blood glucose testing supplies and use them. The finding comes from a large Cochrane review of previous studies that took place in many countries.
1 comment - Posted Mar 17, 2012
According to a study of patients newly diagnosed with type 2 diabetes, 35 percent of the time their physicians did not follow the American Diabetes Association (ADA) guideline that calls for prescribing a generic drug first. The study, conducted by researchers from CVS Caremark, Harvard University, and Brigham and Women's Hospital, reviewed the pharmacy claims of 254,000 patients who were started on a diabetes medication in January 2006 and December 2008. One-third of the treatment regimens did not adhere to the ADA guideline.
0 comments - Posted Mar 13, 2012
Sometimes I feel like an idiot. It usually happens when I read a blog by one of my favorite "D" parents telling about how their children are handling life with type 1 diabetes. These brave kids put up with the same things that adults with diabetes do, and some are literally too young to even understand what's going on. Reading about these little warriors makes me regret even more the fact that I wallowed in self pity all afternoon just because my blood sugar didn't cooperate flawlessly during my daily walk.
2 comments - Posted Mar 6, 2012
The latest clinical guidelines for treating type 2 diabetes from the American College of Physicians (ACP) indicate that when diet, exercise, and weight loss fail to control blood sugar levels in early type 2 patients, physicians should prescribe metformin as the first drug therapy.
1 comment - Posted Mar 1, 2012
February 2012
"I knew I didn't eat a totally healthy diet because bread is a big weakness of mine. Worse, exercise was something I kept planning to do but hadn't gotten around to," recalls 62-year-old Laura M., who lives in a New York City suburb. "I had been feeling more tired than usual and had a cut on my right leg that seemed to be healing slowly, but other than that I felt fine. When during the course of an annual check-up, my doctor said I had diabetes, I practically fell apart."
1 comment - Posted Feb 28, 2012
The unconditional love of a dog can be an amazing source of strength and resilience for its owner. Eight-year-old Madalaine Hembraugh and her foster dog, Petey, are living proof of that. They both have type 1 diabetes, and they have formed a bond that is helping to heal them both.
1 comment - Posted Feb 27, 2012
During my 14 years with type 1 diabetes and my time spent interacting with the diabetes online community, I constantly hear the same theme: Doctors aren't listening to their patients, and their bedside manners are deteriorating. Every day, it seems, I hear about people who have been treated as if they are simply a number or dismissed as uneducated in their own health conditions.
3 comments - Posted Feb 26, 2012
A team of neurologists has issued a new set of recommendations for the treatment of diabetic neuropathy, including drugs and other treatments that have been found to be the most effective therapies for the condition.
13 comments - Posted Feb 25, 2012
British researchers say that metformin, the drug most often used to treat prediabetes and type 2 diabetes, could provide potential protection against endometrial cancer in women.
0 comments - Posted Feb 24, 2012
A study of medical claims data from more than 136,000 men shows that men with diabetes are much more likely to require invasive therapies for erectile dysfunction than men without diabetes. The therapies, which are the next steps beyond oral treatments, are second-line suppositories or injections and third-line surgeries to implant prostheses.
1 comment - Posted Feb 23, 2012
As a woman with diabetes, you may have noticed that you face unique challenges, from where to place your insulin pump, to pregnancy, to hormone fluctuations. Many diabetes books offer general diabetes advice, but few focus on women beyond just a short chapter. That is, until now.
3 comments - Posted Feb 20, 2012
You've heard of the blockbuster drug Byetta, a daily injection for type 2 diabetes? Byetta's sister product, Bydureon, which is injected just once a week, has just been approved by the FDA and is available in pharmacies.
2 comments - Posted Feb 17, 2012
There are lots of articles about diabetes, as well as all kinds of information about anemia. But what if you have both? About 25 percent of people with diabetes have some level of anemia. This article explains how the two conditions interact.
2 comments - Posted Feb 16, 2012
My best friend from high school, Katherine, married a wonderful man who was diagnosed with type 2 diabetes a little over two years ago. John Schaaf, now 60, lives with Katherine in Berkeley, Calif., and works for Chevron Corporation in nearby Richmond.
4 comments - Posted Feb 13, 2012
Diabetes doesn't confine itself to a single week or month. It's a year-round condition, and each season offers its own challenges and opportunities for those of us with the disease. We should be prepared to change and evolve as the seasons shift--not only to stay healthy, but also to enjoy all the fun that our dynamic world offers.
1 comment - Posted Feb 7, 2012
The FDA has approved US sales of JANUMET® XR, a daily oral treatment for type 2 diabetes that combines sitagliptin and extended-release metformin. The drug is the fourth oral type 2 diabetes treatment introduced by Merck, which also sells JANUVIA, JANUMET, and JUVISYNC.
0 comments - Posted Feb 6, 2012
After several years of delays and setbacks, Amylin Pharmaceuticals has received FDA approval to begin US marketing of BydureonTM. The first once-a-week type 2 therapy to be offered in the US market, Bydureon is expected to be available by February. Amylin says that its wholesale price will be about $4,200 a year.
2 comments - Posted Feb 3, 2012
January 2012
The first time I worried about traveling with diabetes was after the 9/11 tragedy. I had been offered a trip to New York to attend a writer's conference. I jumped at the chance, looking forward to the conference, sightseeing, shopping, and seeing the musical The Producers on Broadway.
9 comments - Posted Jan 30, 2012
RALEIGH, NC- DiabetesSisters is pleased to announce that registration for the 2012 Weekend for Women Conference opened on January 1, 2012, at 8 AM. The conference, a revolutionary weekend designed specifically for women with diabetes, will take place Friday, May 18, through Sunday, May 20, 2012, at the Marriott City Center in downtown Raleigh.
0 comments - Posted Jan 24, 2012
When your doctor recommends a new drug or treatment for your diabetes, do you know if the doctor has received payment from the company that markets the drug or device? If the Obama administration has its way, you will. It is proposing a new law that will require drug companies to disclose payments made to doctors for research, consulting, speaking, travel, and entertainment-even something as minor as coffee and bagels delivered to a doctor's office for a meeting.
10 comments - Posted Jan 20, 2012
In my work as a prevention health technician in the Lakota community of South Dakota, I encourage people to ask questions and learn the facts about diabetes. Once they are aware of what diabetes is and how they can prevent or control it, they become empowered.
4 comments - Posted Jan 19, 2012
Ethan Lewis, diagnosed with type 1 diabetes at the age of 12, founded GlucoBrands only 11 years later. The company produces a portable, inexpensive, tasty, fast-acting glucose gel that people can take to quickly restore healthy blood sugar levels when they experience hypoglycemia.
1 comment - Posted Jan 16, 2012
LifeScan has introduced the OneTouch® VerioTM IQ, a meter that not only tracks and displays blood sugar patterns, but also announces them with messages, such as "Looks like your blood sugar has been running LOW around this time."
2 comments - Posted Jan 15, 2012
Recently, there has been a great deal of discussion on the subject of testing your blood sugar and taking insulin shots in public. A shocking number of people on social networks have commented that their family members don't want them to test their blood sugar or take their shots in public. They report having to inject in restrooms or even through their clothing to avoid drawing attention or offending their families. One hypersensitive husband even objected when his recently diagnosed wife took a shot in the relative privacy of their car.
38 comments - Posted Jan 12, 2012
Professional snowboarder Sean Busby started competing at age 14 and began training for the Winter Olympics at 16. But in 2004, at age 19, Sean's troubling bouts of thirst and weariness were revealed as symptoms of type 1 diabetes.
1 comment - Posted Jan 10, 2012
My baby girl had just been born. I was in the postoperation room after going through a cesarean section. My husband went to get my parents, who had been waiting for twelve hours in the waiting room. A nurse laid my little girl in an incubator next to my bed and checked her blood sugar, which was normal, in the mid-40 range. Fifteen minutes later the nurse checked her again, and it registered in the mid-30s. I watched as the nurse fed my baby her first ounces of food. I was still too numb to even know that I had legs, much less to be able to wiggle my toes.
4 comments - Posted Jan 6, 2012
Spring Health Solutions, Inc., has released an instructional video describing its Spring Universal Infusion Set, recently approved by the FDA and Health Canada. The video, at www.SpringUniversal.com, is designed to help consumers properly use the product.
0 comments - Posted Jan 4, 2012
As I explained in my previous articles, I was pre-eclamptic and was admitted to the hospital at 37 weeks. I had a migraine that lasted for ten hours after I entered the emergency room. I had experienced migraines before and knew that Tylenol wouldn't ease the pain, so I went untreated even in the hospital. About twelve hours after admission, I was brought to the women's floor, where I waited for my already injected Levemir supply to diminish in my bloodstream.
1 comment - Posted Jan 2, 2012
December 2011
Throughout pregnancy and all the way up until labor, I was adamant that I was not having a cesarean section. I was terrified of being cut open because I know that my healing time is longer due to my lowered immune system. In 2009, I had to go to the emergency room for an infection caused by cutting my leg while shaving, so how could I possibly heal after being opened up to birth a baby?
0 comments - Posted Dec 30, 2011
Vaginal yeast infections are annoying, not dangerous, but they can seriously hamper your sex life, especially if you have diabetes. What's the connection, and what can you do to prevent and treat yeast infections?
3 comments - Posted Dec 29, 2011
Editor' Note: This article continues Katherine Marple's series on pregnancy with diabetes as a complicating factor. For previous articles, enter her name in the search feature at the top right-hand of this website. The next installment, "Birthing Options," will appear on December 30.
1 comment - Posted Dec 27, 2011
Diabetic retinopathy is caused by damage to blood vessels of the retina. Almost everyone who has had diabetes for thirty years or more has some sign of the condition. Now, retinopathy researchers have come up with a device that will be implanted behind a patient's eye to deliver medication on demand. "We wanted to come up with a safe and effective way to help diabetic patients safeguard their sight," said lead author Mu Chiao, a mechanical engineering associate professor at the University of British Columbia (UBC) in Vancouver, in Science Daily. "This new device offers improvements upon existing implantable devices for drug delivery."
2 comments - Posted Dec 26, 2011
Forty-three year old stage and TV actor Stephen Wallem is a jack of all trades when it comes to entertainment. Best known for his one-man musical review, "Off the Wallem," he is also a playwright, composer, and director. Currently, he plays Thor, a gay nurse with type 1 diabetes, on the Showtime series "Nurse Jackie."
1 comment - Posted Dec 25, 2011
Health experts are unanimous that obesity or being overweight are major factors in the onset of type 2 diabetes. So it's no surprise that researchers here and abroad are working to develop weight-loss drugs that can help people shed pounds and lessen their susceptibility to diabetes.
1 comment - Posted Dec 23, 2011
Even the best known actors can't make a hit movie on their own. They need people behind the scenes. Just like those stars of the silver screen, the standard insulin pump can't do its job all by itself. No, the classic-model pump needs an infusion set to deliver its insulin to patients.
0 comments - Posted Dec 21, 2011
If you have diabetes, you know all too well what's going to happen between now and the end of the year. You'll be forced to make some quick and painful decisions at sumptuous holiday feasts. Do you refuse the lavish, carbohydrate-rich fare and give up on the fun of the season? Or do you go whole hog, eating everything in sight, and hope that your insulin or medication can take up the slack?
3 comments - Posted Dec 18, 2011
"I have type 2 diabetes, diagnosed five years ago, and am 67 years old. I have worked very hard to manage this disease, but without the success I would like."
0 comments - Posted Dec 16, 2011
News from Danish pharmaceutical manufacturer Novo Nordisk reinforces the growing trend toward using a two-drug combination in the early treatment of type 2 diabetes. (See "A Conversation About Janumet and Earlier Combination Therapy Type 2 Diabetes" for more discussion about the phenomenon.)
2 comments - Posted Dec 15, 2011
I wish there were a fail-safe manual for diabetes. Just when I'm thinking about how great my blood sugars have been, bam! I see a 300 on my meter, or a 40. It's so hard to know why: The off numbers could be due to hormones, stress, sickness, an incorrect carb count, varying activity levels, or any combination thereof. With diabetes, you really do learn as you go. Here are a few things I have learned along the way.
2 comments - Posted Dec 13, 2011
Drug company Merck aims to give people with type 2 diabetes two treatments for the price of one. The new therapy, called Juvisync, was just approved by the US Food and Drug Administration. It's not a radical new treatment, but instead a helpful combination of two familiar standbys: Juvisync unites the active ingredients in blood sugar-lowering Januvia and cholesterol-lowering Zocor in a single tablet.
0 comments - Posted Dec 10, 2011
November 2011
There's nothing quite like wondering how you're going to pay for prescriptions. I find it odd that we usually don't know what our out-of-pocket cost will be until we're standing in front of the pharmacy staff and praying that we have enough in our wallet to cover it. I often feel like a reality show contestant waiting for the grand total. My pharmacy-based reality show would probably be called "The Biggest Payer," or perhaps "The Amazing Guess," or, aptly, "Survivor." If you've ever walked away from the pharmacy counter embarrassed, panicked, or depressed, you know the feeling I'm referring to. It's a pain no prescription can cure.
37 comments - Posted Nov 26, 2011
Mike Golic is the co-host of ESPN's wildly popular radio show, "Mike and Mike in the Morning." Before beginning work as a broadcaster in 1995, he played for nine years as a defensive tackle in the National Football League, including stints with the Houston Oilers, Philadelphia Eagles, and Miami Dolphins. About five years ago, he was diagnosed with type 2 diabetes. Since then, he has become involved in getting the word out about type 2, including the potential danger of hypoglycemia. He is a spokesman for "Blood Sugar Basics," a website and outreach program co-sponsored by Merck and the American College of Endocrinology.
3 comments - Posted Nov 25, 2011
In one of Devon Inglee's artworks, a teddy bear, the symbol of childhood innocence, lies flat on its back with three menacing syringes piercing its furry tummy. In the background, the bear's owner, a small girl, stands above the teddy eating an apple. Inglee writes, "In ‘Tit for Tat,' a sweet girl contently eats an apple while hiding a large syringe behind her back, oblivious to her beloved, yet murdered toy. This piece deals with the process of anger, mourning, and denial associated with my personal diagnosis of a chronic disease." For the 33-year-old art student, this work is about mourning and letting go of preconceived notions and ideas of what the future will be.
0 comments - Posted Nov 22, 2011
Living with diabetes, you are already hyper-aware of food, but the holidays seem to heighten that awareness. Faced with your aunt's delicious homemade cornbread and your grandma's famous sweet potato casserole, you may find yourself digging through your closet for your old carbohydrate-counting books and guessing at your insulin adjustments. Who wants to go through the holidays with the added stress of high blood sugars and associated mood swings, especially when your family is already driving you nuts? No, thanks.
4 comments - Posted Nov 21, 2011
It's hard being the new person at work. It's even harder when you're the new person and you have diabetes. Whenever I start a new job, thoughts race through my mind: Will I go low while I'm training? Will I have quick access to snacks? Will I be able to check my blood sugar without an audience? How about taking an insulin injection at the lunch table? It isn't easy feeling forced to expose so many personal details to people you just met.
2 comments - Posted Nov 20, 2011
Anyone who has lost a close family member to type 2 diabetes understands the grief and paralysis it creates, especially when the one who died was only 53.
7 comments - Posted Nov 14, 2011
Having diabetes means attending medical appointments regularly. It's entirely possible that at some point, you experienced an incident in which a medical professional hurt your feelings, made a mistake, or told you something completely incorrect. Medical mistakes do happen. While most doctors and nurses are amazing and professional, they are also human. Errors and inappropriate comments can occur. Some simply don't understand all aspects of diabetes.
17 comments - Posted Nov 11, 2011
The introduction of insulin pen devices in the 1980s facilitated accurate and simple administration of insulin for people managing their diabetes on an outpatient basis. The use of insulin in hospitals, however, continues to be associated with medication errors and severe adverse events. Published practice guidelines have helped address insulin error prevention, and the availability of diabetes technologies has presented another opportunity to promote the safe use of insulin in hospitals.
9 comments - Posted Nov 10, 2011
For a person with diabetes who is beginning insulin therapy, the range of products can be overwhelming. The options are often limited by the patient's healthcare plan, however, and the initial selection of a product is frequently influenced by the healthcare provider. With diabetes education tailored to the individual patient, the delivery of insulin through a particular device is achieved by teaching proper injection technique and selecting an appropriate needle.
2 comments - Posted Nov 6, 2011
If you've had diabetes for a number of years, chances are that you remember when there was no Internet access and no diabetes online community. You had no way to look up information online and no instant connection to millions of others around the world living with diabetes. Unless you had a friend nearby with diabetes, there was no one to understand how you felt when your blood sugar numbers were less than stellar, and no one to sympathize with how hard it can be to get your A1C down.
3 comments - Posted Nov 1, 2011
October 2011
The one time I needed a glucagon injection, I didn't have any. I had never been given a prescription for it, had no idea how to use it, and was absolutely clueless about what it did.
1 comment - Posted Oct 29, 2011
Welcome to the second trimester! By now, many type 1s are experiencing fewer hypoglycemic episodes, and insulin resistance is just beginning to rear its head. You're on the other side of the miscarriage worry hump and getting settled into the pregnancy routine. Congratulations! Take a few minutes each day to celebrate your successes and pat your stomach with a smile, knowing you are doing the best you can to give your growing child everything she needs.
0 comments - Posted Oct 26, 2011
Trying to lose weight as an insulin-injecting person with type 1 diabetes couldn't be more frustrating. It gets on my last nerve that exercise can trigger mind-numbing lows, lows that cause me to inhale a portion of those recently burned calories. That said, I don't skip exercise to avoid lows. I just check my blood sugars more often, use caution with my insulin dosing, and follow the advice of my doctors.
22 comments - Posted Oct 21, 2011
A brand new insulin will soon be on pharmacy shelves in the United States if Danish pharmaceutical company Novo Nordisk has its way. The company has filed for approval from the Food and Drug Administration to sell insulin degludec, an original formulation that lasts an extra-long time. Insulin degludec is injected only once a day. Once under the skin, the dose of insulin is absorbed slowly and consistently, allowing for better nighttime control, according to Novo. Most importantly, test subjects had a low rate of hypoglycemia on the drug.
2 comments - Posted Oct 15, 2011
News from Danish pharmaceutical manufacturer Novo Nordisk reinforces the growing trend toward using a two-drug combination in the early treatment of type 2 diabetes. (See "A Conversation About Janumet and Earlier Combination Therapy for Type 2 Diabetes" for more discussion about this phenomenon.) In a study it released in Lisbon, Portugal, at the recent meeting of the European Association for the Study of Diabetes, Novo said that combining its recently released drug Victoza® (liraglutide) with another drug early in therapy helps recently diagnosed type 2s achieve greater blood glucose control than they can with a single drug.
0 comments - Posted Oct 2, 2011
September 2011
What if we could stop the body's immune system from attacking the pancreas in the first stages of type 1 diabetes? What if we could keep the pancreas producing insulin, all the while helping it recover from the autoimmune barrage?
7 comments - Posted Sep 29, 2011
A couple of factors lead to increased risk of insulin shock comas during the first trimester. For many, insulin sensitivity increases and the pancreas isn't yet producing the hormones associated with insulin resistance. In addition, many type 1s will be taken off of their current basal insulin if it is not yet approved for use during pregnancy.
4 comments - Posted Sep 27, 2011
Being a rookie driver on the fast-paced IndyCar racing circuit is pressure enough for any 26-year-old. But for Charlie Kimball, one of four wheel men on businessman Chip Ganassi's IndyCar race team, there's the added need to manage type 1 diabetes while roaring around the track at speeds that often exceed 200 miles per hour.
0 comments - Posted Sep 25, 2011
Scientists have found a protein that plays an important role in allowing our bodies to absorb glucose from our blood. What's more, lower levels of that protein may contribute to type 2 diabetes.
0 comments - Posted Sep 23, 2011
It's that time of year again: flu season. I never thought much about getting a flu shot until fourteen years ago, when I ended up in the emergency room with the flu and a staggering blood sugar of over 800 mg/dL. I had been diagnosed with type 1 diabetes a few years before and had never discussed a sick day plan with my doctor. But during this experience, I discovered that diabetes and the flu get along about as well as a house cat and a junkyard dog.
5 comments - Posted Sep 22, 2011
So, you're pregnant! Many who are in your shoes have worked very hard and diligently to begin this excursion. Others have reached this milestone unintentionally. Either way, you are about to embark on a journey that will completely challenge everything you know about your type 1 diabetes management. These next few months will challenge your motives, your emotions, your determination, and everything that makes up who you are. So sink your heels in. Take each step one at a time.
5 comments - Posted Sep 20, 2011
Scientists have found a protein that plays an important role in allowing our bodies to absorb glucose from our blood. What's more, lower levels of that protein may contribute to type 2 diabetes.
0 comments - Posted Sep 19, 2011
It may sound silly to say this, especially in this era of computing and high technology, but in our house, one of the most important tools in managing diabetes is a notebook, an ink pen, and three brightly colored magic markers. Of course, I'm talking about the logbook. That's not to say we don't also rely on complicated software to help track our daughter's blood sugars. But when it comes to understanding and using the data to our advantage, there is some truth to the age old belief in hands-on training.
1 comment - Posted Sep 16, 2011
My son just turned twenty. For the first time, we didn't have a cake, ice cream, friends, balloons, or presents. He spent the day in jail. With vivid memories of his heroin-addicted evening in the ICU several months ago, we had nursed high hopes that his life would be on the mend. But healing takes time, and life doesn't always deliver the happy ending we long for.
9 comments - Posted Sep 14, 2011
Here's the scenario: You're a famed prosecutor who happens to be on an insulin pump. One of the criminals you put away years ago has been released from prison, and he's eager for revenge. This is a particularly cunning criminal, so he hatches a subtle plan. He hacks into your insulin pump, giving you a massive dose of insulin without warning. As you drive to work one day, you begin to feel woozy. That's odd, you think, looking down to where the pump attaches to your stomach. I just ate....
1 comment - Posted Sep 10, 2011
"If you weren't having this conversation with me, who, other than your wife, would you be having it with?" That question, in response to something I'd said about treating my nine-year-old daughter's diabetes, was posed to me over the phone by a friend I had made less than six months earlier. She has a daughter too, the same age as mine, who also has type 1. Their diagnosis came a couple of years before ours, so I respect her experience and opinion, and so does my wife, Franca.
0 comments - Posted Sep 9, 2011
When you live with diabetes, there's a lot to do. Checking blood sugars. Counting carbs. Exercising. Not to mention all those fun-filled doctors' appointments. So the last time your physician or diabetes educator suggested ketone testing, it's completely understandable that your head was nodding but your mind was thinking "No way, Jack." But before abandoning the idea completely, there are a few things you should know.
5 comments - Posted Sep 8, 2011
Combination therapy, in which doctors prescribe more than one drug to treat type 2 diabetes, is a fairly common practice. However, most newly diagnosed type 2 patients start off with metformin or a sulfonylurea and don't go on a two-drug therapy until their first drug begins to lose its effectiveness. But combination therapy could soon become an earlier option for people with type 2.
2 comments - Posted Sep 7, 2011
An estimated 34 million Americans will be on the road during Labor Day weekend, many of them with type 2 diabetes. Road travel can interfere with blood sugar management and lead to low blood sugar, which can cause serious complications, such as loss of consciousness, if not treated quickly.
1 comment - Posted Sep 6, 2011
When people are diagnosed with diabetes, things can seem pretty overwhelming. In a short time, they have to absorb a daunting amount of information and start making significant decisions about the way they live their lives.
0 comments - Posted Sep 3, 2011
August 2011
As an NFL quarterback, Jay Cutler makes his living putting a football into the hands of an open receiver before getting slammed to the ground by a huge defensive lineman. It's a stressful occupation, all about timing, a little luck, and seeing the big picture in a split second.
8 comments - Posted Aug 31, 2011
Utah-based Essential Preparedness Products (EPP) offers an emergency storage case for people with diabetes, called Diabetic med-EcaseTM. The yellow cases, made of high-impact material, are waterproof, airtight, and can float. Buyers of the $69.99 product receive foam inserts for both type 1 and type 2 needs and can outfit the case accordingly.
5 comments - Posted Aug 30, 2011
Spices not only add zing to meals, but they may also reduce the high levels of triglycerides produced by eating high-fat meals.
0 comments - Posted Aug 28, 2011
My name is Katherine Marple, and I've had type 1 diabetes for 13 years. I'm the first in my family to have the disease, so I've done most of the research and made most of the discoveries on my own. One of those discoveries was the power of metformin (in addition to insulin) to help me control my diabetes.
16 comments - Posted Aug 18, 2011
Charlie Kimball, the first and only driver with type 1 diabetes in the history of the Indy Racing League to race cars at its highest level, needs your help: Just as when he's racing, Kimball finds himself neck-in-neck in a competition. In this case, he's looking to win the Firestone Tire-iffic Award and you can help him out by voting for him---but you only have till Thursday, August 11, to do so.
2 comments - Posted Aug 10, 2011
In 2004, pro snowboarder Sean Busby was on the top of the world.
12 comments - Posted Aug 8, 2011
Low doses of metformin and rosiglitazone seem to delay the onset of type 2 in prediabetic people who have impaired glucose tolerance, according to a Canadian study. However, although the drug combination was effective over the first year of the study in helping to control glucose levels and insulin resistance, it was not effective subsequently in delaying the onset of insulin resistance and pancreatic beta cell deterioration.
0 comments - Posted Aug 7, 2011
A Boston-based study has found that vitamin D supplements can reduce the risk of developing type 2 diabetes in people with prediabetes by improving their beta cell functioning.
2 comments - Posted Aug 3, 2011
A study in the British medical journal The Lancet shows that type 2s who received once-daily or thrice-weekly injections of degludec, a very long-acting insulin, maintained blood glucose levels similar to patients receiving daily doses of insulin glargine. The results point the way to a possible reduction in the number of injections that type 2s who take insulin would need over any seven-day period. In both the United States and the United Kingdom currently, about one in every three type 2 patients injects insulin at least once daily.
0 comments - Posted Aug 1, 2011
July 2011
Boehringer Ingelheim and Eli Lilly have begun sales of Tradjenta, a drug for type 2 diabetes, in U.S. pharmacies. The drug (generic name linagliptin) comes in tablet form and is intended to compete with Amylin Pharmaceuticals' Byetta, which is injected, and Merck's Januvia, which also competes with Byetta. Both are well-established in the U.S. market.
2 comments - Posted Jul 27, 2011
Patients who have partial lipodystrophy, a condition that often leads to diabetes and high triglycerides, are benefiting from metreleptin, an investigational treatment being developed by Amylin Pharmaceuticals.
0 comments - Posted Jul 24, 2011
With severe weather predicted for Tuscaloosa, Alabama, Meredith Cummings thought carefully about where to park her car-eyeing the large trees in her historic neighborhood-when she arrived home on the afternoon of April 27. As she walked to her door, she reassured herself: Those trees had been there for more than 100 years. What were the odds of them coming down today?
0 comments - Posted Jul 22, 2011
Italian researchers have found that increased consumption of omega-3 fatty acids leads to a decrease in insulin resistance, a common precursor to the development of type 2 diabetes. It also improves lipid profiles and adiponectin levels. (Adiponectin is a protein that is involved in metabolizing glucose and fatty acids. Low levels are associated with insulin resistance, diabetes, atherosclerosis, and obesity.)
0 comments - Posted Jul 21, 2011
Erin lay on a bed in the emergency room, finally serious about getting help. Her second episode of diabetic ketoacidosis in a single year had sent her to the hospital shaking and vomiting. For the past seven years, she had been driven by one desire: to lose forty pounds. She refused to give herself her full dose of insulin, fearing weight gain. She hadn't seen her endocrinologist or checked her blood sugar for a year or two.
5 comments - Posted Jul 18, 2011
Nipro Diagnostics, Inc., and NeuroMetrix, Inc., have announced that they will seek opportunities to sell their soon-to-be-introduced NC-stat® DPNCheckTM neuropathy test in retail medical clinics nationwide. The test, conducted onsite, evaluates neuropathies, including diabetic peripheral neuropathy (DPN).
1 comment - Posted Jul 16, 2011
Nobody thought for even a second that Crystal Bowersox's second-place finish on "American Idol 2010" meant that the 26-year-old was headed back to her native Elliston, Ohio, to resume a quiet life.
1 comment - Posted Jul 14, 2011
Immunologists at a research institute in Melbourne, Australia, say they have successfully tested a nasal spray that suppresses an immune response in people who are genetically disposed to type 1. The test, performed by scientists at the Royal Melbourne Hospital, is the first time that the spray has been tried on humans.
3 comments - Posted Jul 13, 2011
Victoza, a drug aimed at type 2 diabetes, may turn out to be a boon for type 1 diabetes patients as well. A small clinical study shows that patients with well-controlled type 1 who took Victoza daily for just one week experienced a 15 percent drop in their blood sugar levels. Patients who took the drug over a full 24-week test period needed less and less insulin, decreasing their average mealtime dose by seven units and their all-day insulin requirement by eight.
2 comments - Posted Jul 11, 2011
As I write this, my nineteen-year-old son is in the intensive care unit because of a heroin addiction. He is trying to stop, and the withdrawal is wreaking havoc. His body is bruised and battered beyond belief.
15 comments - Posted Jul 10, 2011
Rensselaer Polytechnic Institute in upstate New York is working on a new approach to blood sugar monitoring that could open the door to an artificial pancreas. The plan is to develop an automated monitoring system so sophisticated that it can take into account the often great differences in blood sugar levels and insulin sensitivity among people with type 1 diabetes.
4 comments - Posted Jul 9, 2011
The Internet allows consumers to shop for deals on anything imaginable, even prescription drugs. The economic struggles that many currently face, paired with the increasing cost of healthcare and prescription drugs, have created an environment in which counterfeit drug makers can prosper.
1 comment - Posted Jul 7, 2011
Recently, we published an article by Hope Warshaw, MMSc, RD, CDE, titled "From Old Dogmas to New Realities. "In the article, Hope voiced the opinion that a low carb diet is not the only dietary option for people with diabetes, and that, in fact, such thinking is an "old dogma." In response, we received a number of strongly worded comments advocating the low carb diet as the only way to go.
48 comments - Posted Jul 6, 2011
If you have diabetes, you're more likely to be depressed than people without the disease.
5 comments - Posted Jul 5, 2011
June 2011
One of the classic effects of cannabis on people is raging hunger-the "marijuana munchies." The drug has been used to good effect on people with diseases that diminish appetite, helping them to regain a healthy interest in food. So it is a bit ironic that British drug maker GW Pharmaceuticals has created a cross-bred cannabis plant whose appetite-suppressing qualities could be used to treat type 2 diabetes.
2 comments - Posted Jun 30, 2011
The main question that doctors---and patients---ask about a prescription drug is simple: Does it work? Does this medicine improve the condition it's prescribed for?
0 comments - Posted Jun 25, 2011
You can add any third drug you want to the standard metformin-sulfonylurea combination used to treat type 2 diabetes, including insulin, alpha-glucosidase inhibitors, thiazolidinediones, glucagon-like peptide-1 agonists, or dipeptidyl peptidase-4 inhibitors. None of them provides a decisive superiority in blood glucose control. That's the conclusion of a Brazilian meta-study of 18 drug trials published in the May 17, 2011, issue of the Annals of Internal Medicine.
0 comments - Posted Jun 23, 2011
With Father's Day just around the corner, I thought it would be nice to stop for a moment and reflect on what dads do for us, especially dads who have diabetic children. The pressure and emotional aspects of diabetes can be overwhelming, not to mention the stress it can put on a family. For every needle prick, shot, and counted carb my father (and mother) helped me with, I want to say thanks.
21 comments - Posted Jun 19, 2011
Over the last decade, dramatic changes have occurred in our understanding of the onset and progression of prediabetes. Lightning speed changes have also occurred regarding the therapies available to achieve optimal blood glucose control. Even with all of this change, however, many old dogmas hang on. It's time to become aware of the new realities. In this article, I focus on two common old dogmas and the new realities.
2 comments - Posted Jun 16, 2011
Statistics from the 2011 Medco Drug Report show that diabetes drugs accounted for 16.1 percent of the overall increase in U.S. spending on therapeutic drugs in 2010. The report states that the increase is due to the growing number of Americans who have diabetes.
5 comments - Posted Jun 15, 2011
More than ten million kids head off to summer camp each year. Just because your child has diabetes doesn't mean that he or she must be left out of this rite of passage. Wherever you live, there are specialized camps to help your child have a great and safe experience.
2 comments - Posted Jun 12, 2011
The U.S. Food and Drug Administration has said that starting on November 18, 2011, it will restrict retail pharmacy sales of three diabetes drugs manufactured by GlaxoSmithKline: the stand-alone Avandia (rosiglitazone) and the combination drugs Avandamet (rosiglitazone and metformin) and Avandaryl (rosiglitazone and glimepiride).
0 comments - Posted Jun 11, 2011
Whenever I tell someone that I have type 1 diabetes, the first words that I typically hear are "I'm terrified of needles! I could NEVER give myself a shot!" But needles are the least of my fears when it comes to my disease. I have bigger fish to fry. Concerns about daily management, combined with fears of heart problems, blindness, and kidney failure, equal one very stressful disease.
5 comments - Posted Jun 10, 2011
The makers of "PhoneMyDoctor," a new telemedicine service, say it offers the ability integrate patient calls, doctor feedback, pharmacy ordering, and follow-up instructions into one documented record, using a medical practice's existing telephone equipment.
0 comments - Posted Jun 7, 2011
A few months ago, I had the privilege of traveling to Australia to present at a conference of athletes with diabetes. During the meeting, prizes were awarded to everyone who scored exactly 5.5 mmol/L (99 mg/dL) on their glucose meter. You should have seen it! Anyone who measured close to 5.5 was testing again and again, hoping for that magic number to pop up. Fingers were suffering, but the test strip manufacturers were making out like bandits.
1 comment - Posted Jun 5, 2011
Amylin Pharmaceuticals has announced that it will collaborate with the Juvenile Diabetes Research Foundation to test a combination of Symlin and insulin in injectible form as a type 1 therapy.
0 comments - Posted Jun 3, 2011
Type 2 patients who use only a sulfonylurea are less likely to take anti-depressant drugs than diabetes patients on other medications. That's the conclusion of a report delivered recently in Honolulu at the annual meeting of the American Psychiatric Association.
0 comments - Posted Jun 1, 2011
May 2011
"Nutrient Depletions" is a new smart phone app that allows users to see which of their prescription medications may be draining nutrients from their body. The app, available at iTunes stores for $1.99, works on Apple's iPhone, iTouch, and iPad products.
4 comments - Posted May 31, 2011
Here's news that has been receiving big play in U.S. and European media: British scientists have found that a gene called KLF14 acts as a "master switch" that controls other genes found in body fat-genes that are major factors in such conditions as type 2 diabetes, obesity, high cholesterol levels, and levels of glucose and insulin. The finding, by researchers at King's College London and Oxford University, could lead to treatments for diabetes, obesity, and related metabolic disorders by targeting the gene.
2 comments - Posted May 30, 2011
U.S. insulin pump maker Medtronic and blood glucose monitoring system maker LifeScan have reached the end of their three-year contract in which LifeScan was an exclusive provider to Medtronic.
1 comment - Posted May 29, 2011
A recent article in the Chicago Tribune reports that patients using Lipitor, Actos, or Plavix may start enjoying savings of up to 90 percent as patents on those drugs expire. The three drugs comprise a significant percentage of the $300 billion brand-name U.S. pharmaceutical market, according to the Tribune.
2 comments - Posted May 27, 2011
Swimsuit season lasts for at least five months in the South. The good news is that we live close to the beach, but the bad news is that after 25 years of living with diabetes (and three Caesareans), my body is starting to read like a map of my medical journey.
8 comments - Posted May 25, 2011
French drug maker Sanofi-aventis says that results from a Phase III trial of its experimental type 2 diabetes drug lixisenatide show that the drug successfully lowered patients' blood glucose levels and body weight, but did not increase the risk of hypoglycemia.
0 comments - Posted May 23, 2011
New Jersey's Hackensack University Medical Center has announced that it will partner with Dr. Camillo Ricordi to test a surgical procedure that could hold the key to a cure for type 1 diabetes.
11 comments - Posted May 18, 2011
There's more to that little box of pen needles than meets the eye, according to Holly Hartshorn of UltiMed. In early March, UltiMed launched a 50-count box of UltiCare pen needles into the marketplace. We spoke to Holly to find out exactly what kind of thought goes into such a product before it appears on pharmacy shelves.
3 comments - Posted May 17, 2011
A Danish study of 107,806 adults taking various diabetes medications has found that three drugs are the most effective at lowering the risk of cardiovascular disease and death: metformin, gliclazide (not marketed in the US), and repaglinide (Prandin). Other common diabetes medications, including glimepiride, glibenclamide (glyburide), glipizide, and tolbutamide, were linked to a higher risk of death both from all causes and from heart attack and stroke.
1 comment - Posted May 13, 2011
Dr. Jonathan Beach is a 35-year-old emergency medicine physician who has had type 1 diabetes for 31 years. He owns and operates Urgicare, a wellness center that includes The Northeast Center for Diabetes Care and Education in Plattsburgh, New York, an isolated rural community that has few other resources for diabetes. This is his story of his life with diabetes and his professional experience with the insulin pump.
5 comments - Posted May 12, 2011
Gene Thornton was in the Army in Germany when he got type 1 diabetes. It was 1965, 46 years ago, and he was 24 years old. This is his story, in his own words.
5 comments - Posted May 10, 2011
Recently, we published an article about the implantable pump "A Miracle Technology for Type 1s: Can It Be Saved?" Following the appearance of this article on the Diabetes Health website, over 100 readers commented, most of them expressing a heartfelt desire for access to this technology in the U.S.A. To read the original article click on link below:
A Miracle Technology for Type 1s: Can It Be Saved?
34 comments - Posted May 5, 2011
Molly Martin is a vibrant and energetic 18-year-old from Texas who's had type 1 diabetes since the age of two. Five years ago, Molly took up motocross racing. She says, "I love riding motocross---it's just you and the bike. I feel free when I ride, like I don't have to think about diabetes. I do have to make sure that I test before I get on and during breaks, to make sure my sugar is doing what it's supposed to be doing. But when I get out there, it's just me and the bike, going."
1 comment - Posted May 5, 2011
Ryan Shafer is a 44-year-old professional bowler from Elmira, New York, who was 19 when he developed type 1 diabetes. For a couple of weeks, he experienced the usual symptoms of weight loss, lethargy, extreme thirst, and frequent urination, as well as vision problems. "Being that age," he says, "I was afraid to go to the doctor. I thought it would just go away." When he finally saw his family physician and was diagnosed, he says, "I was actually relieved--not that I thought diabetes was a piece of cake, but I was glad to know what was wrong with me."
3 comments - Posted May 1, 2011
April 2011
Canadian scientists have found that nobiletin, a substance found in high concentrations in tangerines, thwarted obesity and the onset of diabetes in lab mice. The researchers at the University of Western Ontario fed the mice a high-sugar, high-fat diet that mimicked the diet of many people in Western societies. One group of animals became obese, developing fatty livers and elevated levels of cholesterol and insulin-typical precursors to type 2 diabetes and cardiovascular disease. But a second group of mice, given the flavonoid nobiletin, did not develop the symptoms of the first group. The nobiletin prevented fatty buildup in the liver by blocking the genes that control the production of fat.
4 comments - Posted Apr 30, 2011
Kent David is a 47-year-old licensed civil engineer who has had type 1 diabetes since 1981. This is Kent's diabetes story in his own words.
5 comments - Posted Apr 29, 2011
Chase Pelletier is an up-and-coming kart racer from Canada who is 14 years old. When he got type 1 diabetes just before his eleventh birthday, he recalls, "It was pretty overwhelming at first. But me and my family decided early on that we're not going to get down on diabetes in general, and we're going to try to think of positive ways to deal with it."
0 comments - Posted Apr 28, 2011
We all know by now that fat isn't necessarily a bad thing. Enough advertisements and recommendations for fish oil and omega-3 supplements have appeared over the past few years to make that clear. But what if "good fat" isn't just about eating fish or a taking a fishy-tasting supplement? What if that good fat can be found in a common cooking oil?
0 comments - Posted Apr 27, 2011
Recently I had the pleasure of attending the Barbara Davis Center's "Management of Diabetes in Youth" conference, held every other year in beautiful Keystone, Colorado. The focus is on all of the latest and greatest in type 1, and it's a real treat to have so many of the best names in this field gathered in one place. The Barbara Davis Center (BDC) is one of the premier programs in the world focusing on type I diabetes management, and the one (Dr. Peter Chase, to be precise) who brought us the famed" Pink Panther" book, Understanding Diabetes - the reliable handbook of type 1 diabetes that many parents of newly diagnosed kids rely on.
3 comments - Posted Apr 25, 2011
Every year four million baby teeth fall out, and 1.4 million wisdom teeth are pulled out of our collective mouth. Until recently, the only entity really interested in all those teeth was the tooth fairy. But all that changed in the year 2000, with the discovery that dental pulp contains adult stem cells. In the not-too-distant future, those stem cells might be used for growing new islet cells to cure diabetes. The problem is, how to keep the teeth nice and fresh until that hoped-for day. That's where Provia Laboratories comes in, with their Store-A-Tooth service.
1 comment - Posted Apr 24, 2011
The National Institutes of Health has awarded a $1.15 million grant to a researcher at Eastern Virginia Medical School to investigate a protein that may prevent obese people from developing type 2 diabetes.
0 comments - Posted Apr 22, 2011
Medtronic, Inc., says that the U.S. Food and Drug Administration has approved the marketing of the company's CareLink® Personal 5.4 Therapy Management Software for the Mac OS platform.
4 comments - Posted Apr 21, 2011
Phil Southerland's autobiography is an inspirational coming-of-age memoir about a type 1 baby who wasn't supposed to live. But his doctor's dismal prediction didn't take into consideration his mother's indefatigable determination that her baby would thrive no matter what, and Phil's own fierce drive to conquer every single challenge he encountered, including his diabetes. It's an engrossing book, a sports adventure story with a medical subplot and a roster of dynamic characters, the most dynamic of whom is Phil himself. If we could harness his energy, our dependence on foreign oil would be a thing of the past.
2 comments - Posted Apr 20, 2011
Mike Fisher is a 23-year-old from Ontario, Canada, who's been snowboarding since he was 13 years old. At the age of 18, he was involved in a motorcycle crash that necessitated the amputation of one leg below the knee. He says, "At first, I felt that my life was coming to a crashing halt. But I just pushed myself to recover as fast as possible and get my life back on track, go to school, get back into snowboarding and motorcycles-just anything so that my life wasn't affected at all. I had a lot of support, and I would say that I was pretty optimistic about it and took it almost as a challenge. By the time that I was 19, I was happy. I was walking again, I was back in college in London, Ontario, and everything was good. The accident was a minor setback to me, and I rose above it. I was just continuing with my life."
12 comments - Posted Apr 19, 2011
What if there were a technology that could make people with type 1 diabetes feel absolutely wonderful, completely healthy, better than they ever realized was possible? And what if it were about to disappear? Well, there is such a technology, and it is in serious jeopardy. It's called the implantable insulin pump, currently made by Medtronic. This is the story of four people who have been using this device for 20 years, and their desperate crusade to keep it from disappearing forever.
117 comments - Posted Apr 17, 2011
Researchers at the U.S. National Institute of Environmental Health have found that people with diabetes have a significantly increased risk of developing Parkinson's disease. Despite that finding, they say that there are too few data to support a causative link between diabetes and Parkinson's.
0 comments - Posted Apr 16, 2011
Three weeks out of every month, my diabetes is well controlled. But the fourth week, the one before my period, is a nightmare. My sugars are astronomically high--I can't even look at a carbohydrate without my sugar spiking. I'm exhausted and cranky, and I can't get comfortable.
8 comments - Posted Apr 15, 2011
Greetings from Philadelphia International Airport! Airports are fascinating places...great for seeing what people look like and how they act under unusual circumstances. At this moment, I see a lot of truly overweight people. Most folks are treating the moving walkway like a ride at Disney World–just standing there, inching slowly along and staring blankly at the passing drywall. I don’t know…maybe the two sights are related. Have we really become this lazy? Have we “convenienced” our way out of being in shape? Have electronic toilet flushers, soap dispensers, and water faucets taken away our last opportunity to burn any calories at all?
0 comments - Posted Apr 14, 2011
Beta blockers, which many people with diabetes take to control high blood pressure, may be one of the reasons why type 2s often tend to gain and keep weight. That's the conclusion of a study from St. Vincent's Hospital in Sydney, Australia.
0 comments - Posted Apr 8, 2011
Jeff and Natalie Kolok live in northwestern Vermont with their three children: Naomi, 16, and Johanna and Nicholas, each ten years old. Both Johanna and Nicholas have type 1 diabetes, Johanna since age four and Nick since age six.
1 comment - Posted Apr 7, 2011
Every spring since 1999, the Diabetes Education and Camping Association (DECA) has distributed our publication to their young campers. In honor of their youthful enthusiasm, our springtime issue always focuses on people who inspire us, from the young to the old. In this issue, we bring you the stories of people who refuse to let their diabetes limit them, people whose example re-ignites our determination to live our very best and healthiest lives. As a publisher, I am always seeking inspiration, and each of these individuals is a fresh reminder of what we can do if we put our minds to it.
1 comment - Posted Apr 3, 2011
Prodigy Diabetes Care is an aptly named company, a very young enterprise with the talents of a much older organization and a future that promises prodigious rewards. It was founded in 2006 by Ramzi Abulhaj and Rick Admani, two brothers from Palestine who are its sole owners. In the five years since then, they have built a company that is successfully competing against the diabetes old guard by focusing on engineering and a unique marketing strategy.
8 comments - Posted Apr 2, 2011
As we wrote back in 2008, the EndoBarrier is a very clever way to simulate the effect of a gastric bypass without the unpleasant scalpel part. It looks like a long clear plastic stocking, and it's simply threaded through the patient's mouth and stomach, down to the small intestine, where it lines the intestine's upper section (the same part that is bypassed in traditional surgery). Food slips right through it, but digestive enzymes are trapped on its other side. The two don't get to join forces until a couple of feet further downstream, so the effect on diabetes is a lot like that of a bypass: It resolves the symptoms of type 2 diabetes.
0 comments - Posted Apr 1, 2011
March 2011
This List defines terms that people with prediabetes commonly encounter as they learn more about the condition.
1 comment - Posted Mar 29, 2011
The U.S. Food and Drug Administration has accepted an application to review dapagliflozin, a drug for the treatment of type 2 diabetes that is being developed by Bristol-Myers Squibb and AstraZeneca.
0 comments - Posted Mar 22, 2011
Evolution works in strange ways. What serves as an advantage at one point in time can sometimes prove a problem later, when the world has changed. It looks like that might be the case with type 2 diabetes, according to researchers from San Diego, California.
2 comments - Posted Mar 21, 2011
Tony Flores is a 50-year-old native of El Salvador who works as a construction foreman. He was diagnosed with type 2 diabetes about 12 years ago, after an eye doctor told him it would be a good idea to get his blood sugar checked. He recalls, "I did the test, and they got all freaked out and told me, ‘Oh my god, your A1C is at 12%. You have diabetes type 2. You've got to cut the sugar, you've got to stop drinking orange juice and soda."
1 comment - Posted Mar 15, 2011
Weight loss can help people with type 2 diabetes control their blood sugar and avoid potential health risks associated with the disease. Did you know that losing even seven percent of your body weight can lower blood sugar, reduce blood pressure, and improve cholesterol levels1?
"Consider diabetes as a disease that has different phases--with the central feature a disorder of insulin production and insulin use," said Roberta Anding, MS, RD/LD,CSSD,CDE. Anding is a clinical dietitian and certified diabetes educator at Baylor College of Medicine, as well as a national spokesperson for the American Dietetic Association. "To better control and lose weight safely with type 2 diabetes, it is important to consider the type and amount of food on your plate."
4 comments - Posted Mar 12, 2011
Edward Danielson developed type 1 diabetes 79 years ago, in 1931, only a decade after the discovery of insulin. Edward's wife of 67 years, Dorothy, recalls, "In the spring of 1930, when Edward was ten, his teacher told his mother that he ought to be checked by a doctor because something seemed to be wrong. His mother got on the streetcar with Edward and they went down to see the doctor, who said, ‘There's nothing wrong with him. He's just slow.' So they went home. In the fall of the same year, his new teacher said, ‘Something's wrong with Edward--he ought to be checked out by a doctor.' So they went back, and that doctor diagnosed him with diabetes. They kept him in the hospital for a month because the doctors then didn't know that much about diabetes 1."
1 comment - Posted Mar 10, 2011
You know that awful feeling when a sugar low is coming. I break out into a cold sweat, feel panicky, get nauseated, and have trouble answering extremely simple questions like "Do you need to eat?" Well, I was feeling it again, and again, and I didn't know why. That's what I hate the most: When things go wrong, but I think I've been doing everything right.
1 comment - Posted Mar 8, 2011
My almost 20 years as a diabetes educator have been memorable in many ways, but certain moments stand out more than others. Because blood glucose testing is an important part of diabetes management for everyone I see, I try to assess each person’s skills and habits in this key area. I’ll never forget the time I asked a client how often he changed his lancet. He had been diagnosed with type 1 diabetes about four years earlier and was checking regularly, so it seemed like a reasonable question. He proceeded to look at me with a puzzled expression and say, “You mean you’re supposed to change those things?”
0 comments - Posted Mar 8, 2011
Novo Nordisk, the world's largest insulin manufacturer, has joined the Diabetes Prevention and Control Alliance (DPCA), a group whose goals are to reduce people's risk of developing diabetes and to work with people who already have it.
1 comment - Posted Mar 4, 2011
Ten years ago, an astute physician diagnosed me with Type 2 diabetes. I exhibited none of the classic symptoms of rapid weight loss, extreme thirst, and frequent urination. I attributed fatigue to my job. For about a year before diagnosis, I experienced what I thought were yeast infections and treated them with over-the-counter medications. I later learned that this condition is a symptom of diabetes. I am non-insulin dependent.
0 comments - Posted Mar 3, 2011
Hispanics are almost twice as likely as non-Hispanic whites to have type 2 diabetes, and more than a third of working adult Hispanics do not have health insurance. For this audience, Jane Delgado, PhD, has written The Buena Salud Guide to Diabetes and Your Life. Available in both Spanish and English, it's a culturally sensitive and reassuring book that dispels myths and presents detailed science while gently guiding readers toward the right path in caring for their diabetes. The tone is conversational, as Dr. Delgado speaks to her readers like a family member who knows them well and has their best interests at heart.
0 comments - Posted Mar 2, 2011
Scandal swirling around a former diabetes drug has upended medical regulation in France, with the country's health minister promising tough new reforms.
0 comments - Posted Mar 1, 2011
February 2011
A couple of diabetes recalls are in the works, one for a group of insulin cartridges manufactured by Animas and another for the entire line of ACCU-CHEK® FlexLink Plus infusion sets, manufactured by Roche.
0 comments - Posted Feb 28, 2011
Ellen Granberg is an obesity sociologist who studies the processes that people go through when they lose weight and keep it off. As she says, "If the problem were that we don't know what people should eat to lose weight, that would be one thing, but we don't have that problem. There are a hundred weight loss plans out there that are perfectly good. We understand all about the physiology of weight loss maintenance and the metabolic impacts, but nothing about the social and emotional impacts. People who sustain weight loss over time move through a lot of different challenges."
0 comments - Posted Feb 27, 2011
Researchers at the Children's Hospital in Boston, led by Umut Ozcan, MD, have found a regulatory protein that lowers blood sugar when it is high due to either lack of insulin or a decreased sensitivity to insulin.
0 comments - Posted Feb 24, 2011
New University of Georgia research has found that a statin drug that is often known by the brand-name Lipitor may help prevent blindness in people with diabetes. In a study using diabetic rats, lead author Azza El-Remessy, assistant professor in the University of Georgia College of Pharmacy, and her colleagues found that statins prevent free radicals in the retina from killing nerves important to maintaining vision. The results of the study are published in the March edition of the journal Diabetologia.
0 comments - Posted Feb 23, 2011
In order to undergo gastric bypass surgery, you must have a BMI of at least 35. If you have type 2 diabetes and would like to undergo the surgery to alleviate your diabetes symptoms, you are out of luck unless you are also morbidly obese. A few less weighty type 2 patients have taken matters into their own hands by deliberately gaining enough weight to qualify, but now there is a less drastic way to qualify for the operation.
0 comments - Posted Feb 23, 2011
When a young person with type 1 diabetes leaves home for the first time, it's often a difficult adjustment for the parents as well as their child. Tyler Stevenson is 20 years old, in his second year at Florida State. This is what he told us about his life in college with diabetes.
4 comments - Posted Feb 22, 2011
Ross Valley Pharmacy, tucked away inside a larger building of clinics, is not a big place, but it's very very busy. Its owner, Paul Lofholm, PharmD, has a vision of the pharmacist's role that goes far beyond simply putting pills in bottles. He sees pharmacists as integral members of the healthcare team who can fill the gaps in patients' education about their conditions and their medications.
0 comments - Posted Feb 21, 2011
Ross Valley Pharmacy, tucked away inside a larger building of clinics, is not a big place, but it's very very busy. Its owner, pharmacist Paul Lofholm, has a vision of the pharmacist's role that goes far beyond simply putting pills in bottles. He sees pharmacists as integral members of the healthcare team who can fill the gaps in patients' education about their conditions and their medications.
0 comments - Posted Feb 20, 2011
Everywhere you look, there seems to be a great tasting high carb meal, dessert, or snack staring back at you. While away at college last fall, I found a t-shirt picturing a cupcake above a skull and crossbones. For me, that image really sums up how we need to deal with being diabetic while being constantly tempted by sugary treats.
4 comments - Posted Feb 16, 2011
Can't make insulin? That might not be a problem, according to Dr. Roger Unger, the lead researcher on a mouse study out of UT Southwestern Medical Center. As Dr. Unger stated in a press release, his findings "suggest that if there is no glucagon, it doesn't matter if you don't have insulin....In adulthood, at least with respect to glucose metabolism, the role of insulin is to control glucagon. And if you don't have glucagon, then you don't need insulin...If diabetes is defined as restoration of glucose homeostasis to normal, then this treatment can perhaps be considered very close to a ‘cure.' "
1 comment - Posted Feb 16, 2011
Nearly one in six people in the United States has no health insurance. If you have diabetes, that's a very tough position to be in. There are, however, resources that can cut the costs that you have been paying out of pocket for medicines and supplies.
0 comments - Posted Feb 14, 2011
A new analysis from Johns Hopkins University shows that women with diabetes are 50 percent more likely to die if they have breast cancer. Why? The challenges of diabetes management play a role, as well as women's overall health.
0 comments - Posted Feb 14, 2011
Many tragic complications of diabetes, including amputations, heart attack, stroke, and blindness, are due to blood vessel damage. According to Xiaochao Wei, PhD, of the Washington University School of Medicine in St. Louis, all that vascular damage may be caused by a shortage of one enzyme: fatty acid synthase, or FAS.
0 comments - Posted Feb 11, 2011
It's hard enough to be pregnant, but pregnancy with diabetes is especially challenging because it's so difficult to keep blood sugar within a normal range at a time when hormones are surging. All women try their best with the tools that they have, but even so, about half of all babies born to mothers with type 1 diabetes are overweight or obese at birth because of too much sugar in their mothers' blood. Mothers with high blood glucose levels also increase their child's risk of congenital malformation, stillbirth, neonatal death, preterm delivery, and neonatal admission.
0 comments - Posted Feb 9, 2011
INDIANAPOLIS and NEW YORK - Eli Lilly and Company and the Juvenile Diabetes Research Foundation (JDRF) today announced that they have signed an agreement to fund early-stage research that could enable patients with type 1 diabetes to regenerate insulin-producing cells destroyed by the disease.
0 comments - Posted Feb 4, 2011
The Chicago Athenaeum: Museum of Architecture has announced its 60th annual Good Design Awards, which honor "quality design of the highest form, function, and aesthetic." Guess which paragon of contemporary design won an award this year? An insulin needle. Called the NovoTwist and made by Novo Nordisk for use with insulin pens, this marvel of design has a bayonet fitting that allows "just twist" attachment and detachment to compatible pens, and an audible and tactile "click" that confirms attachment of the needle.
3 comments - Posted Feb 1, 2011
January 2011
Insulin has a companion, and it's called amylin. Amylin is a small hormone that is released along with insulin by the beta cells of the pancreas in response to a meal. When people are insulin-deficient, they are amylin-deficient as well. Amylin wasn't even discovered until 1970, and it was not until the 1990s that scientists began to figure out what amylin does. But they now know that it partners with insulin to help control blood sugar levels, each in its own way:
1 comment - Posted Jan 28, 2011
It's Labor Day weekend in Pittsburgh, just outside of the Steelers' Heinz Field, and the Bret Michaels Band has come home for some hard-driving rock and roll. The 20,000 screaming fans are a generational mix, shrieking 16-year-old girls side-by-side with moms and dads who have temporarily abandoned their parental roles to dance, sing the familiar words to "Look What the Cat Dragged In," and howl into the nighttime air. On stage is Bret Michaels, the boy from Butler, Pennsylvania, a coal mining town just an hour north.
16 comments - Posted Jan 27, 2011
The MOLLY and LINDSEY Diabetes Research Foundation at Hackensack University Medical Center (HUMC) and the Diabetes Research Institute (DRI), a Center of Excellence at the University of Miami Miller School of Medicine, have joined forces to find the cure for Type 1 Diabetes. Together they will form the Hackensack-Miami DRI Federation Project, a think tank of East Coast specialists who will fast-track the best research ideas coming out of the labs and put them to the test in clinically meaningful ways, thus shortening the path to a cure for those with type 1 diabetes.
5 comments - Posted Jan 26, 2011
Your young primary care doctor may not know a lot about diabetes, according to a study led by Stephen Sisson, MD, of the Johns Hopkins School of Medicine. "When I graduated from residency here, I knew much more about how to ventilate a patient on a machine than how to control somebody's blood sugar, and that's a problem," said Sisson in a press release. "The average resident doesn't know what the goal for normal fasting blood sugar should be. If you don't know what it has to be, how are you going to guide your diabetes management with patients?"
2 comments - Posted Jan 26, 2011
The kuriously named Kombiglyze XR, a combination of Onglyza (saxagliptin) and the old reliable metformin, has arrived at pharmacies and is available by prescription to people with type 2 diabetes. It's similar to Janumet, an older medication that's a combination of Januvia (sitagliptin) and metformin.
0 comments - Posted Jan 25, 2011
It doesn't matter if you're a computer geek or complete technophobe: If you've ever made the effort to download your blood glucose meter, you probably don't have a clue about what to do with the data once you've gotten it. That needs to change. Those of us who live with diabetes need to become more adept at analyzing our own data, to see what's working and what isn't both for our own sake and that of our time-strapped healthcare providers. .
2 comments - Posted Jan 25, 2011
MannKind Corporation has finally received a complete response letter from the FDA regarding its inhalable insulin, Afrezza. (The FDA issues a complete response letter when it completes its review of a New Drug Application, but cannot yet approve the application as is.) What the FDA wants now is a couple more clinical trials with the new form of the inhaler (one in patients with type 1 diabetes and one in patients with type 2 diabetes), with at least one trial including a treatment group using the older form of the inhaler, in order to obtain a head-to-head comparison of the two devices.
0 comments - Posted Jan 24, 2011
Self-management is the key to healthy living with diabetes, but there are always challenges to maintaining optimum blood glucose levels. Lagging motivation and focus can be obstacles, and adjusting diet and medications to meet changing conditions is challenging. If you have ever wished for a person to help you improve your skills, someone who could offer informed guidance between appointments with your doctor - you may have been wishing for a diabetes coach. Diabetes coaches are personal trainers for individuals with insulin-dependent diabetes. This unique branch of diabetes education delivers ongoing, one-on-one consulting from a trained certified diabetes educator.
0 comments - Posted Jan 24, 2011
Taking 10,000 steps a day, or walking about five miles, is very, very good for you. It's even better than walking 3,000 steps a day, which is also extremely beneficial if you walk briskly enough to do it in 30 minutes. The 10,000 steps philosophy is not new--there's even a weight-loss book or two on the topic. But now the 10,000 step regimen has also been linked to an increase in insulin sensitivity in middle-aged adults.
1 comment - Posted Jan 20, 2011
Most type 2 meds work by increasing insulin production in one way or another. The extra insulin lowers blood sugar by ushering it out of your bloodstream and into your cells, where it may, unfortunately, make you fat. Wouldn't it be nice if instead, you could lower your high blood sugar by just flushing it right down the toilet?
2 comments - Posted Jan 17, 2011
"Fatty liver" doesn't sound very threatening. In fact, it sounds almost cute, like Fatty Arbuckle. Unfortunately, like Fatty Arbuckle, it's not what it seems. Nonalcoholic fatty liver disease is the most common liver disease in the United States, comprising a quarter of all liver disease and responsible for a rising number of liver transplants. Approximately 20 percent of Americans may be lugging around a fatty liver.
1 comment - Posted Jan 13, 2011
The Diabetes Research Institute Foundation (DRIF) announced a new, first-of-its-kind partnership aimed at helping the more than 200,000* Broward County, Florida, residents affected by diabetes. Diabetes Research Institute Live Well Broward County is a joint effort of the Diabetes Research Institute Foundation, Walgreens in South Florida, LifeScan and a cadre of local physicians that will help residents "Manage Well, Stay Well and Live Well" with diabetes.
0 comments - Posted Jan 12, 2011
The crowd in the small Boston theater laughed and clapped. The comedy show was a good one, and I was enjoying it from a cramped seat in the balcony. It was October 29, a Friday, and while it was brisk outside, winter hadn't yet clamped down.
0 comments - Posted Jan 11, 2011
Introducing "Type-1 University" (T1U) - the online school for people with diabetes who use insulin, including parents and caregivers. The school can be found only in cyberspace - at www.type1university.com
2 comments - Posted Jan 7, 2011
Sitagliptin (Januvia) has long been used to reduce blood sugar in people with type 2 diabetes, but a new study indicates that it can do the same for those with type 1 diabetes. Sitagliptin is a DPP-4 inhibitor; that is, it inhibits, or temporarily prevents, the enzyme DPP-4 from destroying a helpful hormone called GLP-1. GLP-1, which is released by the gut when food arrives there from the stomach, lowers blood sugar by causing the release of insulin, reducing the secretion of glucagon, and slowing stomach emptying and nutrient absorption.
3 comments - Posted Jan 7, 2011
Talk about a win-win situation! It seems that many aphrodisiacs--herbs that boost sexual energy and function--can also bring down blood sugar, cholesterol, and/or blood pressure. At least four herbs have shown these double benefits in scientific studies.
1 comment - Posted Jan 6, 2011
My trip began as I flew from Dallas to my home town of Philadelphia and then caught an early Amtrak train to New York City. Growing up in the Philadelphia area had given me an appreciation for U.S. history, but today I was going to learn something new: the history of diabetes. My daughter, Sarah, was diagnosed with type 1 diabetes in 2003, yet I didn't know much about the history of the disease. Living every day with the stress and worry that many parents have, I felt I had no time to spend learning how we got to the modern treatments we have today. I had focused only on doing my job as caregiver and supporter of my daughter. I was looking forward to learning something new.
10 comments - Posted Jan 3, 2011
December 2010
The Albert Einstein College of Medicine at Yeshiva University in New York City has received a $600,000 grant from the American Diabetes Association to study the effects of resveratrol on lowering impaired glucose tolerance in older adults.
2 comments - Posted Dec 30, 2010
Arena Pharmaceuticals and Eisai Inc. recently released results of a phase 3 clinical trial for lorcaserin, a weight-loss drug they are developing in partnership. The trial, called BLOOM-DM (Behavioral modification and Lorcaserin for Overweight and Obesity Management- Diabetes Management), targeted patients with type 2 diabetes who are overweight or obese.
2 comments - Posted Dec 28, 2010
A new study finds that combining the newer diabetes drug exenatide with insulin provides better blood sugar control in patients with type 2 diabetes than insulin alone and helps promote weight loss.
1 comment - Posted Dec 27, 2010
Most holiday stories are comforting and familiar, wrapped up with the happiest of endings. But the tales that swept the nation this Thanksgiving were sometimes distressing and strange, and the one told by Laura Seay has no resolution or simple solution. Seay was one of the travelers caught in the center of the debate over the Transportation Security Administration's forceful new screening methods.
6 comments - Posted Dec 23, 2010
Abbott Diabetes Care today announced that it has initiated a recall of 359 lots (approximately 359 million strips) of Precision Xtra®, Precision Xceed Pro®, MediSense® Optium, Optium, OptiumEZ and ReliOn® Ultima Blood Glucose Test Strips in the United States and Puerto Rico.
1 comment - Posted Dec 22, 2010
Being diagnosed with type 2 diabetes means a lot of change in your daily life. From blood glucose monitoring to watching what you eat to losing weight, it's hard to keep track of the changes you need to make to keep diabetes under control. One aspect of diabetes care that sometimes falls through the cracks is oral health care, which, if ignored, can lead to serious health complications.
2 comments - Posted Dec 22, 2010
Research firm Frost & Sullivan, a leading international healthcare consulting company, released a market study analyzing and estimating the demand for Pepex Biomedical Inc.'s new biosensor technology for blood glucose monitoring for diabetes sufferers worldwide. The researchers interviewed diagnosed diabetics, diabetes educators, endocrinologists, and manufacturers of biosensors, blood glucose meters, or other clinical diagnostic or patient monitoring equipment suppliers for the study. The Frost & Sullivan report concluded that the Pepex Trio technology has the "potential as a new standard for measuring blood glucose levels."
6 comments - Posted Dec 21, 2010
A 10-year study by Harvard University scientists found that diabetes puts people at risk for depression and that depression puts people at risk for type 2 diabetes. The two-way connection between the diseases was discovered in 55,000 nurses surveyed over the decade.
1 comment - Posted Dec 17, 2010
Novo Nordisk, a world leader in diabetes care, has partnered with Chip Ganassi Racing, LLC to create the Novo Nordisk Chip Ganassi Racing team for the 2011 IZOD IndyCar season. The team will sponsor a new entry in the series driven by American racecar driver Charlie Kimball. This partnership makes Kimball one of the first drivers from the 2010 Firestone Indy Lights series to move up the official "Road to Indy" with a full season sponsorship.
0 comments - Posted Dec 17, 2010
With nearly 16 million Americans living today with pre-diabetes, a condition that is the precursor to type 2 diabetes, and half of all Americans expected to have some form of diabetes by the year 2020, healthy eating is more important than ever (1,2). But here is some good news: a recent scientific study shows that incorporating almonds into your diet can help treat and possibly prevent type 2 diabetes, as well as cardiovascular disease.
0 comments - Posted Dec 15, 2010
(Reuters) - Stem cells can be transformed into the pancreatic cells needed to treat diabetes and into complex layers of intestinal tissue, scientists demonstrated in two experiments reported on Sunday.
6 comments - Posted Dec 13, 2010
"Congress passed a multi-year renewal of the Special Diabetes Program (SDP), ensuring that studies on promising diabetes treatments and avenues toward a cure continue uninterrupted. As the father of a son living with type 1 diabetes, and as CEO of JDRF, one of the leading advocates for the renewal of this program, I applaud the U.S. government for its continued commitment to end this disease.
2 comments - Posted Dec 13, 2010
"Don't leave home without it" has a whole new meaning this holiday season. With holiday travel up from last year and increased security- and consequent delays- at airports, it's more important than ever for those with diabetes to properly prepare for their holiday travel.
0 comments - Posted Dec 10, 2010
Valeritas, Inc., a medical technology company committed to the development and commercialization of innovative drug delivery solutions, announced today that the US Food and Drug Administration has cleared the company's V-Go Disposable Insulin Delivery Device for the continuous subcutaneous delivery of insulin in preset basal rates and with on-demand bolus dosing for adult patients requiring insulin. V-Go devices will be available in a preset basal rate to deliver 20, 30 or 40 Units of insulin in one 24-hour period (0.83 U/hr, 1.25U/hr or 1.67U/hr respectively) and on-demand bolus dosing in 2 Unit increments (up to 36 Units per one 24-hour time period).
1 comment - Posted Dec 9, 2010
November 2010
Too often our preconceptions of work-limiting disabilities are confined to suddenly devastating conditions, such as spinal cord injury or stroke. We rarely consider how diseases such as diabetes can be just as debilitating and just as costly to a family. With November being recognized as National Diabetes Awareness Month, we should remember the people who are unable to work due to the complications of diabetes and who need the benefits to which they are entitled under Social Security Disability Insurance (SSDI).
4 comments - Posted Nov 30, 2010
The newest threat to patient health may not be the flu or other epidemics. It could be a major shortage of prescription drugs. The shortage has reached the level of a "national public health crisis," according to a survey conducted by the Institute for Safe Medication Practices (ISMP) this summer. Survey respondents said shortages in the past year were "the worst ever, without a glimmer of hope for any improvement in the near future."
0 comments - Posted Nov 27, 2010
Insulet Corp., the leader in tubing-free insulin pump technology with its OmniPod® Insulin Management System, recognizes the outstanding achievements of Christopher Gorham, age 12, of Waterford, Michigan for bringing home both silver and bronze medals in the Sparring and Forms competitions at the 2010 World Karate/Kickboxing Council World Championships held in Albufeira, Portugal. Chris is a 2nd degree black belt in training for a 3rd degree black belt; he has been in martial arts since he was four years old, competing all over the world.
0 comments - Posted Nov 25, 2010
A new drug for type 2 diabetes started showing up in drugstores this week, according to manufacturer Santarus. The FDA-approved drug, called Cycloset, takes an distinctive -- and not well understood -- approach to reducing blood sugar levels. The pill apparently works by increasing dopamine activity in the hypothalamus, a part of the brain. Dopamine is a brain chemical that plays a big role in people's behavior, mood, and ability to sleep. Scientists theorize that glucose intolerance and insulin resistance may in part result from abnormal activity of this chemical, and that upping dopamine activity may iron out these problems.That's the theory, at least: the drug's exact workings aren't known. But it seems to do the trick.
0 comments - Posted Nov 24, 2010
A friend of mine recently remarked that she wants her family to eat healthier, but she just doesn't know that much about nutrition. Though I can sympathize with her in some ways (nutritional education is a daunting and never-ending process), I do feel that the overall American attitude toward food is that ignorance is bliss. It reminds me of the preteen character in the movie Son-In-Law, who puts his sister's bra cups over his ears and tells his parents in a taunting voice, "I can't hear you!" Unfortunately, what you don't know CAN hurt you, and not just you, but also your family.
3 comments - Posted Nov 22, 2010
The Centers for Medicare & Medicaid Services (CMS) is encouraging all Medicare beneficiaries to take advantage of the annual Open Enrollment period to make sure they have the best coverage available to meet their health care needs in 2011.
1 comment - Posted Nov 16, 2010
Both celiac disease (CD) and type 1 diabetes (T1D) are autoimmune diseases. In CD the immune response is triggered by the ingestion of gluten, resulting in chronic inflammation and villous atrophy in the small intestine. Treatment requires permanent elimination of gluten from the diet. In T1D, pancreatic islet beta cells are damaged resulting in loss of endogenous insulin production. Treatment includes daily insulin injections combined with meal planning and exercise. Nutrition management of the individual with both T1D and CD can be challenging for both the patient and the dietitian.
0 comments - Posted Nov 16, 2010
Imagine a pandemic. A disease comes into a community and then spreads across borders, causing disability and death in its path. Scientists fight to contain its spread, and doctors try to mitigate its effects. Most people associate this kind of scenario with a pathogen: a virus or bacteria, like HIV or avian flu, that has found a way to exploit the human body. In fact, however, the overwhelming majority of pandemics are the result of noncommunicable diseases that are not spread by pathogens: conditions like cancer, heart disease, and type 2 diabetes.
1 comment - Posted Nov 12, 2010
WASHINGTON, D.C., Nov. 10, 2010 --- Diabetes experts at a meeting convened by the U.S. Food and Drug Administration (FDA) and the National Institutes of Health (NIH) took the next step in advancing efforts toward the development of an artificial pancreas: putting forth clinical recommendations to ensure the safe and effective testing of artificial pancreas technology in real-life situations. We are pleased at today's meeting there was a strong consensus among leading clinicians, researchers and industry leaders regarding the path toward outpatient studies for both low-glucose suspend and artificial pancreas systems.
5 comments - Posted Nov 10, 2010
Over the years, I have had many exercisers with diabetes ask me why they're gaining weight instead of losing it. There are two possible answers to that question. One answer is that muscle is heavier than fat, so if you are gaining muscle while losing fat-especially in the early stages of a new exercise program-your scale weight probably doesn't reflect your positive changes in body composition (i.e., less fat, more muscle).
2 comments - Posted Nov 10, 2010
With just a few days left to 14 November, we imagine that a lot of you are making those final touches to your World Diabetes Day celebrations or have already started your awareness activities. Here's a further look at what will be taking place around the world to mark the day:
0 comments - Posted Nov 6, 2010
HOLLYWOOD, FL- Beginning today, thousands of people who want to help put an end to diabetes can be part of the cure by participating in the Diabetes Research Institute Foundation's online campaign at BePartoftheCure.org. Kicking off National Diabetes Awareness Month, the Be Part of the CURE campaign is a fun and meaningful way for people living with diabetes, their family and friends, and anyone concerned about curing this devastating disease to literally participate in the "CURE."
1 comment - Posted Nov 1, 2010
October 2010
Regular physical activity and exercise are recommended for the general population for overall improved health. However, exercise of moderate intensity increases the risk of hypoglycemia during and following exertion in those with type 1 diabetes mellitus (T1DM). Accordingly, exercise guidelines for T1DM focus on prevention of exercise-induced hypoglycemia.
0 comments - Posted Oct 31, 2010
In a proof-of-concept study presented at the 2010 Annual Clinical Congress of the American College of Surgeons, the researchers note that the matrix not only helps to understand the micro-architecture of the pancreas, but also prolongs the survival and preserves the function of the islets. Islets survived longer in the bio-artificial matrix than in conventional transplantation sites, and they produced significantly more insulin when challenged with glucose.
0 comments - Posted Oct 30, 2010
Tarra Robinson was afraid that she was going to lose her job. Diagnosed with type 1 diabetes when she was 18 months old, Tarra had recently developed hypoglycemic unawareness, which affects about 17% of type 1 diabetics. Tarra was passing out at work, and once she even crashed her car when her blood sugar dropped unexpectedly. She went on a pump and tried a CGM, but nothing seemed to help. She was still having frequent, dangerous lows.
0 comments - Posted Oct 28, 2010
As flu season approaches, many people are debating whether they should get a flu shot. As everyone knows, getting the flu is not fun. In fact, it can be downright miserable. But for those with diabetes, the flu can mean more than a cough, running nose, and body aches--it could mean more severe complications, and sometimes even death.
0 comments - Posted Oct 27, 2010
Imagine that you're a miner. Imagine you have diabetes (that, at least, shouldn't be too hard). Now, imagine that you have to spend two months trapped underground with other miners. How would you do?
0 comments - Posted Oct 24, 2010
Getting enough magnesium in your diet could help prevent type 2 diabetes. Dr. Ka He of the University of North Carolina at Chapel Hill and colleagues have found that people who consumed the most magnesium from foods and vitamin supplements were about half as likely to develop diabetes over the next 20 years as people who took in the least magnesium.
0 comments - Posted Oct 22, 2010
European researchers have reported that when they transplanted fecal matter from healthy thin people into obese people with pre-diabetes, the latter group's insulin sensitivity notably increased. (Insulin sensitivity is the body's ability to properly use the insulin hormone to regulate the amount of glucose in the bloodstream. Pre-diabetes exists when increasing resistance to insulin creates higher-than-normal blood sugar levels, a precondition to the onset of full-blown type 2 diabetes.)
1 comment - Posted Oct 19, 2010
Calibra Medical has announced that it received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market its FinesseTM insulin patch-pen for up to three-day use with Novo Nordisk's Novolog® rapid-acting insulin. This much-anticipated step closer to market release follows the announcement in January that Calibra received FDA clearance for the device for use with Eli Lilly's Humalog® rapid-acting insulin.
1 comment - Posted Oct 18, 2010
University of Michigan scientists have identified events inside insulin-producing pancreatic cells that set the stage for a neonatal form of non-autoimmune type 1 diabetes, and may play a role in type 2 diabetes as well. The results point to a potential target for drugs to protect normally functioning proteins essential for producing insulin.
0 comments - Posted Oct 15, 2010
The day I learned that I had type 1 diabetes was no doubt one of the most heart-wrenching, confusing, and angry days of my life. But I quickly decided that I had to channel those feelings into something productive, something worthwhile. I gained confidence as a person with diabetes, and even though, yes, the shots stung, I wasn't going to flinch. Welcome to my life.
0 comments - Posted Oct 11, 2010
In July, I went to order a refill of my pump and was refused. My account was overdue, and my pump company wouldn't issue a refill until I could pay at least $400 of the $1200 I owed. I didn't have $400. I am a freelance writer and stay-at-home mom with a knack for stretching my husband's paycheck. I'd been making small monthly payments of about $50 because that was all we could afford, but now they wouldn't send me any more. So I went to the pharmacy and bought a box of syringes for $25. I didn't want to go back to multiple daily injections, but I didn't see that I had a choice.
1 comment - Posted Oct 9, 2010
Dance Out Diabetes is a non-profit organization that addresses a critical component missing in most diabetes programs: PHYSICAL ACTIVITY! Our mission is to help individuals prevent or manage diabetes through dance and education.
0 comments - Posted Oct 6, 2010
We all know of Paul and Mira Sorvino, the legendary father and daughter actors who have graced the small and big screens for decades. Paul has played such classic characters as Paulie Cicero in the film Goodfellas and Sgt. Phil Cerreta on the TV series Law & Order and is a well-known chef and singer, while Mira has starred in over 30 movies and won an Academy Award in 1995 for her role as Linda Ash in Mighty Aphrodite.
0 comments - Posted Oct 5, 2010
Last week, sanofi-aventis announced the upcoming launch of the blood glucose meters BGStar® and iBGStarTM (developed by sanofi and its partner AgaMatrix), which should be available in early 2011.
1 comment - Posted Oct 4, 2010
Twenty years ago, when I opened Sugar Happy Diabetes Supplies in San Francisco, people would open the front door, lean in, and ask, “I’m curious. Are there enough people with diabetes for you to stay in business?” My reply was always, “You would be surprised by how many people have diabetes.”
0 comments - Posted Oct 1, 2010
A national epidemiologic study finds a strong, consistent correlation between adult diabetes and particulate air pollution that persists after adjustment for other risk factors like obesity and ethnicity, report researchers from Children's Hospital Boston. The relationship was seen even at exposure levels below the current EPA safety limit.
0 comments - Posted Oct 1, 2010
September 2010
I’m back. I started working with Diabetes Health 10 years ago. At that time, Diabetes Health was the one publication open enough to talk about a subject that was controversial at that time… Lower Carb Options. That was my column, and I got a lot of slack from it. I didn’t understand why. People with diabetes want and need lower carb options. What was the problem with giving people options? That’s what Diabetes Health is all about – teaching people there are healthy options. Now it’s common to see lower carb options for people who have diabetes.
0 comments - Posted Sep 29, 2010
Diabetes research is on the cusp of new advances in treatment options and in understanding the underlying causes of both type 1 and type 2 diabetes. Among those are potential treatments using stem cells to regenerate a patient's ability to produce insulin, as well as upcoming clinical trials of a vaccine that potentially could prevent type 1 diabetes.
2 comments - Posted Sep 27, 2010
Do you ever wish you could leave your diabetes at home? Maybe you're at a holiday party, chit chatting with your buds gathered around the bar enjoying an adult beverage (or two), maybe grazing at the table of cookies, cakes and other tempting morsels. "Oh, I think I'll try one of those. Maybe one of those too. I didn't bring my diabetes with me, so I don't have to think about it tonight." Diabetes is not last year's outfit you can leave at home, or a bad relationship you can dump and move on. It is more like a tattoo. It goes everywhere with you.
0 comments - Posted Sep 24, 2010
The U.S. Food and Drug Administration today announced that it will significantly restrict the use of the diabetes drug Avandia (rosiglitazone) to patients with Type 2 diabetes who cannot control their diabetes on other medications. These new restrictions are in response to data that suggest an elevated risk of cardiovascular events, such as heart attack and stroke, in patients treated with Avandia.
0 comments - Posted Sep 23, 2010
New research findings reveal that one of America's favorite colorful fruits, blueberries, have properties that help to improve factors related to pre-diabetes and decrease inflammation in obese men and women. Chronic low-grade inflammation related to obesity contributes to insulin resistance, a major factor in the development of type 2 diabetes. "This is an excellent example of the importance of clinical trials to building our knowledge-base in helping to improve public health," said Steven Heymsfield, PBRC Executive Director
0 comments - Posted Sep 21, 2010
The presence of amyloid protein may produce a chain reaction which destroys vital insulin-producing cells. Researchers based in Dublin, writing in the journal Nature Immunology, say future drugs could target this process. Amyloid is implicated in many other diseases - most notably Alzheimer's.
0 comments - Posted Sep 17, 2010
In late July, five teenagers and five adults hiked to the summit of Mount Shavano, one of Colorado's famed 14,000-foot peaks. For this particular group, the journey to the top of Shavano was designed to be an intensive educational experience on the topic of diabetes management. Each teenager had type 1 diabetes, and the adults were mentors dedicated to helping the teens feel more in control of the disease. The team made it to the summit by performing countless blood sugar tests, counting carbs, and experimenting with insulin pump basal rates. The outfit behind the expedition was Testing Limits, an outdoor adventure club just for people with diabetes, operated by the non-profit Insulindependence.
0 comments - Posted Sep 17, 2010
The JDRF is celebrating its 40th anniversary this year. A lot has changed in the past four decades. One change has to do with the organization's name. JDRF stands for Juvenile Diabetes Research Foundation. Years ago we called what we now know as type 1 diabetes, Juvenile Onset Diabetes Mellitus (JODM). We called it that because we knew (or thought we knew) it was the kind of diabetes that occurred in children. We now know that type 1 diabetes occurs in people of all age groups. There was a lot we didn't know 40 years ago, one of which was that type 1 diabetes is an autoimmune disease.
0 comments - Posted Sep 16, 2010
If you are meeting a friend for a drink after work or attending a holiday party where alcohol is being offered, is it a health risk or a benefit? The medical and nutrition literature reports that moderate consumption of alcohol can offer some health benefits, particularly for your heart. The Dietary Guidelines for Americans 2005 defines drinking in moderation as no more than one drink per day for women or two drinks per day for men. One drink, by definition, is a 12-ounce beer, eight-ounce glass of malt liquor, five ounces of wine, or 1.5 ounces of hard liquor. Moderate alcohol consumption may reduce the risk of having a heart attack or stroke, lower the risk of developing gallstones, and prevent the development of type 2 diabetes in people with pre-diabetes. Studies show that those benefiting from moderate consumption are middle-aged and older adults. It is not recommended, however, that anyone begin drinking or drink more frequently on the basis of health considerations.
0 comments - Posted Sep 15, 2010
In type 1 diabetes, the body relentlessly attacks and destroys its own insulin-producing pancreatic beta cells. But a study by Joslin Diabetes Center scientists now has firmly established that some of these cells endure for many decades in a small group of people with the disease-offering clues to potential treatments for preserving and even restoring the crucial cell population.
0 comments - Posted Sep 14, 2010
On July 2, 2010, when Lt. Jose Lopez took the podium at the recent Children With Diabetes Friends for Life Annual International Conference in Orlando to speak to the parents of children with diabetes, his goal was to use his own story to reassure them about their children's future. "What I most wanted to convey to them was that people with diabetes, especially children, can do normal stuff and live their dreams. I am not a super hero - and I did it."
0 comments - Posted Sep 14, 2010
The exact cause of type 1 diabetes is still unknown, but international researchers have found a link between the blood sugar disorder and a network of immune system genes.
0 comments - Posted Sep 13, 2010
Going back to school can be a little scary for someone with diabetes. There are a lot of things to think about when it comes to making it through the school day without having problems with your blood sugar levels. In school, we strive for that all important "A" on a test; to score 100. The same is true about blood sugar/glucose levels; the closer I come to keeping my blood sugar level at "100," the better for my health and the better for my grades; high and low blood sugars aren't helpful in keeping a clear, quick-thinking mind.
0 comments - Posted Sep 10, 2010
In my office, there is a box. Nothing fancy, just a plain brown box filled with a collection of "old school" diabetes stuff: "boil and re-use" syringes, urine test tape, screw-driven insulin pumps, medieval injection aids and lancing devices, and so on. Of course, no such collection would be complete without an array of classic blood glucose meters. The oldest one I have is a plug-in-the-wall model called a "Dextrometer" that featured test strip rinsing solution and a red LED display that could burn the retina of anyone within six feet.
0 comments - Posted Sep 9, 2010
Dear Diabetes Health, I am 62 years old. I was diagnosed with type 2 diabetes in 1997, and I am doing OK on metformin. My last A1c was 7.2 %. About a year ago, they put me on medicine for my blood pressure (which was 142/90) and for cholesterol. I started having less interest in sex, which I had really liked before.
0 comments - Posted Sep 7, 2010
Type 2 diabetes and Alzheimer's disease are two distressing, but increasingly common, diseases seen in our aging population. At some point in the future, they may well overwhelm the healthcare system.
0 comments - Posted Sep 5, 2010
The routine breakdown of old bone during skeletal growth has an important role to play in regulating blood sugar, according to Columbia University Medical Center researchers. The process, known as resorption, goes on throughout life. It stimulates insulin release and sugar absorption, helping healthy people maintain normal blood glucose levels. The new study, published in Cell, suggests that skeletal changes could causes diabetes for some and that possible treatments for type 2 diabetes could come from the bone-insulin connection.
0 comments - Posted Sep 4, 2010
The Holy Grail pursued by all diabetes researchers is a complete cure for both the type 1 and type 2 forms of the disease. But until then, the "artificial pancreas," a combination of glucose monitoring and insulin dosing technology, may be as close as they get to a final breakthrough in treating diabetes.
0 comments - Posted Sep 3, 2010
Results of brain surgery on a small group of type 2 diabetes patients point the way to a possible new approach for treating the disease.
0 comments - Posted Sep 1, 2010
August 2010
The Flamingo Flock diabetes awareness campaign is the brainchild of 9-year-old Noah Brokmeier, "The Diabetes Dude." Noah's blue flamingos are landing on lawns nationwide and appearing at big events like the Boston Marathon. Wherever they go, the birds pose for pictures, which are then posted on Noah's website, www.thediabetesdude.com. The location of the birds is also flagged on his "official flamingo tracking map," to show the progress and growth of the campaign.
0 comments - Posted Aug 30, 2010
MannKind Corporation announced that the company will supply its novel, ultra rapid acting insulin AFREZZATM (insulin human [rDNA origin]) for use in a study being conducted by the Juvenile Diabetes Research Foundation (JDRF) as part of its Artificial Pancreas Project. The planned two-year study in patients with type 1 diabetes will leverage the unique rapid action of AFREZZA for use in a closed-loop blood sugar monitoring and insulin delivery system, termed the "artificial pancreas" by the JDRF. The study will be managed in conjunction with the Sansum Diabetes Research Institute and the University of California, Santa Barbara.
0 comments - Posted Aug 29, 2010
Working toward the goal of unifying patients' diabetic treatment information in a single place, the PositiveID Corporation hopes to patent a new device that monitors insulin pens. The Insulin Tracker would attach to a user's insulin pen and record the times and amounts of injections. That information would then be sent to a database that allows for comprehensive monitoring. Insulin pens come in disposable and cartridge-replaceable flavors; the tracker can be moved easily from one pen to another.
0 comments - Posted Aug 27, 2010
NaturEra, (http://www.NaturEra.com) a dietary supplements emerging leader, this month announced the launch of its new Sugar Crush dietary supplements would take place at the American Association of Diabetes Educators meeting in San Antonio, Texas. Sugar Crush research has been accepted for Poster presentation at the AADE meeting. The full clinical research study (http://www.naturera.com/Manuscript.pdf) shows that NaturEra's 'Sugar Crush' and 'Sugar Crush Daily' dietary supplement formulas used in combination lower and maintain healthy blood sugar levels for people with diabetes.
1 comment - Posted Aug 26, 2010
In the early days after my type 1 diabetes diagnosis, I sentenced a lot of foods to what I came to think of as my personal DO-NOT-EAT list, often with only slight provocation.
1 comment - Posted Aug 25, 2010
Novo Nordisk announced today the availability of NovoDoseTM - the first-ever mobile insulin dosing guide for physicians to look up dosing guidelines and blood glucose goals for their patients with diabetes, a disease that affects nearly 24 million Americans. The guide is available as an application on iTunes and is specific to Novo Nordisk's modern insulin analog portfolio: Levemir® (insulin detemir [rDNA origin] injection), NovoLog® (insulin aspart [rDNA origin] injection), and NovoLog® Mix 70/30 (70% insulin aspart protamine suspension and 30% insulin aspart injection, [rDNA origin]).
0 comments - Posted Aug 24, 2010
Results of a recently published study show that type 2 diabetes in obese adolescents can affect their ability to learn by altering the amount of sugar that reaches their brains to fuel thinking.
0 comments - Posted Aug 24, 2010
PPARy is a protein that regulates the body's production of fat cells. However, obesity can modify how PPARy works, leading to decreased insulin sensitivity and the development of metabolic syndrome. (Metabolic syndrome is the cluster of factors, including insulin resistance, overweight, high blood pressure, and abnormal blood sugar levels, that is a precursor to type 2 diabetes.)
0 comments - Posted Aug 22, 2010
Gene variants associated with an increased risk for type-1 diabetes and rheumatoid arthritis may confer previously unknown benefits to their human carriers, say researchers at the Stanford University School of Medicine. As a result, the human race may have been evolving in the recent past to be more susceptible, rather than less, to some complex diseases, they conclude.
0 comments - Posted Aug 21, 2010
Since 1970, Joslin Diabetes Center has awarded a 50-year bronze medal and certificate to recognize the remarkable achievement of a successful life with insulin-dependent diabetes for half a century or more. To date there have been approximately 2,663 50-Year Medals awarded by Joslin Diabetes Center. Joslin Diabetes Center has awarded medals to recipients throughout the world, including individuals from Australia, Brazil, Canada, England, Hungary, Japan, Netherlands, Pakistan, Philippines, Russia, South America, Spain, Sweden, and Switzerland.
0 comments - Posted Aug 21, 2010
(Reuters) - Genetic testing might have helped identify people who would become depressed or suicidal while taking Sanofi-Aventis' weight loss drug Acomplia, which might have helped keep the drug on the market, U.S. researchers said on Thursday.
0 comments - Posted Aug 19, 2010
"Absolutely not. I'm not going to mess with that."
0 comments - Posted Aug 18, 2010
"The objective of this clinical trial (research study) is to determine if the medications can rescue the few beta cells that remain soon after the diagnosis of type 1 diabetes; and whether new beta cells can even be regenerated," commented Alex Rabinovitch, MD, Principal Investigator of the trial and Associate Director of The Sanford Project. "The investigational combinations of these medications could possibly allow patients to decrease or no longer need to inject insulin to keep their blood levels under proper control."
0 comments - Posted Aug 12, 2010
And wouldn't it be great if that pill weren't something advertised on late-night TV, but rather a legitimate treatment? A drug called rimonabant, introduced in Europe, seemed to fit the bill at first, but it was pulled from the market in late 2008 due to concerns about psychiatric side effects.
0 comments - Posted Aug 10, 2010
Children who consume a lot of high-fructose corn syrup in soft drinks and processed foods as they're growing up may run the risk of turning many of their fat cells into belly fat when they reach adulthood.
0 comments - Posted Aug 10, 2010
The HEALTHY program, a three-year government-funded intervention in middle schools that was designed to lower overall rates of overweight and obesity among students, has produced mixed results.
0 comments - Posted Aug 8, 2010
Insulin-resistant obese women lost more weight after 12 weeks on a low-carbohydrate diet than they did on a low-fat diet, according to a study conducted by the University of Nevada School of Medicine in Reno. (The study was funded by Jenny Craig, a company that sells diet foods.)
0 comments - Posted Aug 7, 2010
Two recent research studies on humans indicate that resveratrol, a chemical found in red wine and peanuts, increases insulin sensitivity in older and obese people. A third study, done on mice, shows that resveratrol may someday become a powerful tool in therapies directed at macular degeneration and other retinal maladies.
0 comments - Posted Aug 6, 2010
Novo Nordisk presented results demonstrating that once-daily Victoza® (liraglutide [rDNA] injection) achieved significantly greater improvements in blood sugar control compared to placebo among African-American patients with type 2 diabetes. The meta-analysis of phase 3 data from the Liraglutide Effect and Action in Diabetes (LEAD) trials were presented at the 2010 National Medical Association Annual Convention & Scientific Assembly.
0 comments - Posted Aug 5, 2010
Children as young as seven years old can show markers for metabolic syndrome, a condition that raises their risk for type 2 diabetes and a host of other health problems, according to university researchers.
0 comments - Posted Aug 4, 2010
July 2010
Bioengineers at the University of California, San Diego and GlySens Incorporated have developed an implantable glucose sensor and wireless telemetry system that continuously monitors tissue glucose and transmits the information to an external receiver. The paper, published in the July 28, 2010 issue of the journal Science Translational Medicine, describes the use of this glucose-sensing device as an implant in animals for over one year. After human clinical trials and FDA approval, the device may be useful to people with diabetes as an alternative to finger sticking, and to short-term needle-like glucose sensors that have to be replaced every three to seven days.
0 comments - Posted Jul 31, 2010
Last summer, I led the third annual swim-run biathlon for the Barton Center for Diabetes Education, which hosts two Massachusetts camps for children with type 1-Camp Joslin for boys and Camp Clara Barton for girls. It was at Camp Joslin that I met a memorable eight-year-old boy who exemplifies what being a diabetes hero is all about. I'll call him "Adam."
0 comments - Posted Jul 29, 2010
On March 23, 2010, President Obama signed the Patient Protection and Affordable Care Act into law (P.L. 111-148). The health care reform law, which incorporates changes made by the Health Care and Education Reconciliation Act of 2010, makes several important changes to the Medicare Part D drug benefit to reduce Part D enrollees' out-of-pocket liability when they reach the coverage gap, known as the "doughnut hole."
0 comments - Posted Jul 29, 2010
NEW YORK, NY, July 26, 2010 - Recalling the desperate fight for life that used to be waged by juvenile diabetes patients, and commemorating the events of 1921 that inaugurated a new era of hope for them and their families, the New York Historical Society will present the exhibition Breakthrough: The Dramatic Story of the Discovery of Insulin from October 5, 2010 through January 31, 2011. Exploring the roles of science, government, higher education and industry in developing and distributing a life-saving drug, the exhibition will bring to life the personalities who discovered insulin and raced to bring it to the world and will tell the story of one extraordinary New York girl-Elizabeth Evans Hughes, daughter of the leading statesman and jurist Charles Evans Hughes-who was among the very first patients to be saved.
0 comments - Posted Jul 26, 2010
I was in the parking lot of the mall, walking past wheelchair parking, when I noticed a man using the lift gate of his specially equipped van. There he was, lowering himself and his motorized wheelchair down to the ground all by himself. As I walked through the mall that day, I couldn't get the man in the wheelchair off my mind.
0 comments - Posted Jul 26, 2010
Learn Your Risk for Diabetes and Take Steps to Protect Your Health. If you are diagnosed in the early stages of diabetes, you can take better care of yourself and get treatment. If you have pre-diabetes, you can take steps to prevent or delay the onset of type 2 diabetes.
0 comments - Posted Jul 23, 2010
A long-term study on the safety of a popular diabetes drug was put on hold Wednesday by the Food and Drug Administration, while the FDA considers whether it's too dangerous to continue. Several large studies have linked the drug, Avandia, to a higher risk of heart attacks and other heart problems. While other studies have not found the same risk, last week an FDA advisory panel recommended that the drug not be sold without a stronger warning label or possibly limits on who could receive it.
0 comments - Posted Jul 23, 2010
We have known for several years that Hepatitis C, a common cause of liver cirrhosis and cancer, also makes people three to four times more likely to develop Type 2 diabetes. In studying the insulin resistance of 29 people with Hepatitis C, Australian researchers have confirmed that they have high insulin resistance, a precursor to diabetes. However, almost all insulin resistance occurs in muscle, with little or none in the liver, a very surprising finding given that Hepatitis C is a liver disease.
0 comments - Posted Jul 21, 2010
From environmentally friendly hybrid cars and heating with solar power to organic or natural foods, our culture is increasingly embracing green strategies. "Using natural dietary supplements to support healthy blood sugar levels and minimize the impact of glycation is a rational continuation of this green philosophy," says Steven Joyal, MD, vice president of Scientific Affairs and Medical Development for the Life Extension Foundation in Ft. Lauderdale, Florida (www.lef.org). He is also author of the book What Your Doctor May Not Tell You About Diabetes.
0 comments - Posted Jul 20, 2010
(Reuters) - The first new prescription weight-loss pill in more than a decade failed to win backing from U.S.health advisers, who said safety concerns about the drug outweighed its ability to help obese patients shed pounds.
0 comments - Posted Jul 19, 2010
Looking for novel ways to help improve patient outcomes, the Johnson & Johnson Diabetes Institute is using innovative adult education techniques to train diabetes educators around the world. While the cultural and epidemiological differences in each region can be challenging, David L. Horwitz, M.D., Ph.D., FACP, Chief Medical Officer of the Johnson & Johnson Diabetes Institute, feels confident this program can make a positive impact to help improve patient outcomes.
0 comments - Posted Jul 17, 2010
The U.S. Food and Drug Administration's (FDA) Joint Meeting of the Endocrinologic and Metabolic Drugs Advisory Committee and Drug Safety and Risk Management Advisory Committee has completed their evaluation of the scientific research available on the safety of rosiglitazone. The deliberations of the panel reflected the complexity of the issues, with several members voting to add additional warnings or to withdraw the drug from the U.S. market. Ultimately, the final recommendation was to allow Avandia to remain on the market. Now that the expert panel has concluded its meeting, the FDA will review their recommendations and make the final decision on whether the drug remains available to patients.
0 comments - Posted Jul 15, 2010
Medtronic, Inc. announced today that Test B4U Drive, the first-ever, free program for teens with diabetes combining advanced driver skills training with diabetes management education, will be held July 19-21 at The Forum in Los Angeles. In partnership with the Juvenile Diabetes No Limits Foundation, Medtronic will continue the program throughout the summer across the country to teach teens with diabetes that good diabetes management is a key to staying safe behind the wheel.
0 comments - Posted Jul 14, 2010
There's nothing quite like a dip in the Mediterranean Sea at sunset. The warm, clear water, shimmering clouds, and sound of families enjoying aperitifs at beachside cafes--it was the perfect start to a late-summer Italian holiday. We were visiting my boyfriend's brother, who had moved from England to Genoa a few years prior. It was my first time across the Atlantic, so my boyfriend Dunstan and I tried to make it count with 10 days filled with dinners, family celebrations, a road trip to Rome, hiking, and plenty of swimming.
0 comments - Posted Jul 13, 2010
A massive study involving 485 people with type 1 diabetes at 30 locations across North America shows that the combination of an insulin pump and a continuous glucose monitor helps patients achieve significantly lower A1c levels than multiple daily insulin injections.
0 comments - Posted Jul 13, 2010
My diabetes and I have traveled a lot of miles together in nineteen years. Racing Ironman triathlons in Australia, Europe, the Carribean and all over North America, climbing and camping at the top of 14,000 foot Mt. Whitney, and of course dozens of family vacations and business trips. Packing equipment and supplies for an Ironman triathlon and 3 weeks in Australia requires a bit of planning and preparation, but when you have diabetes you feel like you do that for just a weekend out of town. Meters, strips, insulin, syringes, infusion sets, pump supplies, snacks . . . a simple weekend trip becomes a lunar expedition.
1 comment - Posted Jul 10, 2010
Data from the massive ACCORD study on intensive blood sugar control shows that lowering blood sugar levels in people with longstanding type 2 diabetes to near-normal may delay the appearance of signs that point to damage to nerves, eyes, and kidneys, but does not stop their progression toward it.
0 comments - Posted Jul 9, 2010
A study released in late June has brought some welcome news to the makers of Byetta and Januvia: Users of the two diabetes drugs run no greater risk of developing pancreatitis than people with diabetes who take other drugs. In fact, both drugs seem to put users at slightly less risk for the condition.
0 comments - Posted Jul 8, 2010
A clinical trial that used testosterone gel, a topically applied ointment, to increase muscle strength in older men with low testosterone levels was stopped because adverse cardiovascular events increased significantly among patients receiving the treatment.
0 comments - Posted Jul 7, 2010
AFREZZA TM (insulin human [rDNA origin]) Inhalation Powder, a well-tolerated, investigational ultra rapid acting mealtime insulin, as part of a diabetes treatment regimen, provides long-term glucose control comparable to usual insulin therapy but with a significantly reduced incidence of hypoglycemia and less weight gain in patients with Type 2 diabetes, according to a two-year study presented at the American Diabetes Association's 70th Scientific Sessions.
0 comments - Posted Jul 6, 2010
In a recent study of the relationship between vitamin D deficiency and glucose intolerance in people with type 2 diabetes, more than 90 percent of the type 2 diabetes patients were found to be deficient in vitamin D, with their control over the disease worsening as their deficiency increased.
0 comments - Posted Jul 4, 2010
Summer has arrived, and for many, that means it's time to take that long-awaited vacation. Visions of sunny beaches, gourmet meals, mountain resorts, adventurous excursions, and campgrounds dance in our minds. The word "vacation" is typically a synonym for "letting it all go." No worries. No cares. Just pure indulgence. But for people with diabetes, an upcoming vacation can bring on anxiety and stress. For many of us, our disease thrives on routine and predictability, and vacations do not adhere to our everyday lives.
0 comments - Posted Jul 3, 2010
A diet including coconut oil, a medium chain fatty acid (MCFA), helps combat insulin resistance. Insulin resistance is the inability of cells to respond to insulin and take in glucose for energy. The pancreas tries to compensate for insulin resistance by producing even more insulin, but eventually glucose accumulates in the bloodstream. Over time, insulin resistance and obesity can lead to pre-diabetes or full-blown type 2 diabetes.
0 comments - Posted Jul 1, 2010
Depomed, Inc. and Santarus, Inc. announced new data suggesting that patients previously intolerant of metformin may be able to tolerate higher doses of metformin when treated with GLUMETZA® (metformin HCl extended release tablets). The finding will be presented at the 70th Scientific Sessions of the American Diabetes Association (ADA) in Orlando. GLUMETZA is a once-daily, extended release formulation of metformin, and is approved for use in adults with type 2 diabetes mellitus. It is promoted in the U.S. by Santarus.
0 comments - Posted Jul 1, 2010
June 2010
Dear Diabetes Health, I have been married for 14 years. I am 36 and my husband is 39, and we have a seven-year-old daughter. About six months, ago my husband found out that he has type 2 diabetes.
0 comments - Posted Jun 29, 2010
A malfunction in the pancreas's "circadian clock*," the built-in timer found in all living things that regulates major biological processes, may be one of the reasons that people develop diabetes.
0 comments - Posted Jun 29, 2010
White rice and brown rice are reminiscent of those old dramas about identical twins, wherein one turns out to be angelic and the other turns out to be bad news.
0 comments - Posted Jun 28, 2010
One day as I was multi-tasking (making dinner, washing dishes, supervising my daughter, returning phone calls), I suddenly grew very annoyed at the music we were listening to. I had recently purchased a children's CD for my daughter, and it hit me that all the songs sounded the same. What a waste of twelve dollars, I thought, as I headed toward the CD player to shut it off. As I reached down to hit the "off" button, I noticed a small, unfamiliar icon on the display screen. I crouched down to further examine and then laughed aloud.
0 comments - Posted Jun 26, 2010
A Sacramento Superior Court judge has ruled that only school nurses can give insulin shots to children in public schools who have diabetes. The decision by Judge Lloyd Connelly overturned a 2007 California State Department of Education decision that allowed trained school staff, as well as nurses, to administer such injections.
1 comment - Posted Jun 25, 2010
City of Hope researchers have found that bone marrow transplantation with islet cell transplantation shows promise as a treatment for late-stage type 1 diabetes. This combination may enable patients to make their own insulin again. Results from laboratory research led by Defu Zeng, MD, associate professor in the departments of Diabetes Research and Hematology & Hematopoietic Cell Transplantation at City of Hope, were published online this month in the journal Diabetes.
0 comments - Posted Jun 25, 2010
Researchers from the National Jewish Health and University of Colorado Anschutz Medical Campus have found a specific protein fragment, or peptide, that stimulates an immune system attack resulting in diabetes. Their experiments in mice contradict conventional wisdom about such peptides and support work by scientists studying autoimmune diseases.
0 comments - Posted Jun 24, 2010
The American Diabetes Association and the American Cancer Society have issued a joint consensus statement that acknowledges some links between diabetes and cancer but also notes there are numerous questions that have yet to be answered.
0 comments - Posted Jun 23, 2010
(Reuters) - Drug developer Depomed Inc (DEPO.O) said it will recall 52 lots of its diabetes drug Glumetza due to the presence of traces of a certain chemical in the tablet's 500 mg bottle.
0 comments - Posted Jun 22, 2010
Diabetes is often perceived as a physical disease, an issue with one's body. But those of us with diabetes know that it affects every area of our lives, including our emotional, spiritual, and mental health. People with diabetes are more likely to experience depression than the average person, and it doesn't take a doctor to explain why. Diabetes is daunting, complicated, and confusing. There's no one-size-fits-all explanation or treatment plan, and even when we arrive at something that works, diabetes throws us a curveball and we are forced to reinvent our treatment regimen---time, and time, and time again.
0 comments - Posted Jun 18, 2010
IMIDIA ("Innovative Medicines Initiative for Diabetes"), a public private consortium funded by the Innovative Medicines Initiative (IMI), announced today the launch of a project focusing on pancreatic islet cell function and survival. Academia, biotech and pharma industry have joined forces to develop biomarkers and tools to pave the way for improved disease management and ultimately provide a cure for diabetes.
0 comments - Posted Jun 18, 2010
One of the factors that increases the risk of acquiring type 2 diabetes is excess body fat. So it makes sense that losing weight has always been one of the first lines of defense against the disease. Yet people who are slender -skinny, even- sometimes develop type 2. Why is that? Does the fact that a slender person can acquire type 2 negate the need for weight control?
0 comments - Posted Jun 18, 2010
As a type 1 diabetic, I have found that it's a good idea to plan for the unexpected when traveling. Life is full of surprises, and so are vacations. The flight is late. The flight has been cancelled. We had a flat tire or ran out of gas. There is an accident on the highway, and the traffic isn't moving. Who would have ever thought that airline flights would be grounded for five days in most of Eastern Europe because of volcanic ash from an erupting volcano in Iceland? If a diabetic had planned on going for a week-long vacation in England or France and had taken limited insulin, syringes, or infusion sets, he might have been in big trouble. Trying to replenish medical supplies in a foreign country could prove to be very difficult.
0 comments - Posted Jun 16, 2010
There are so many weight loss programs out there, sometimes it is hard just to keep track of them, let alone choose one that will work. Add in the factor of diabetes, and the path to weight loss becomes harder to navigate and often contains land mines that we never even knew existed.
0 comments - Posted Jun 15, 2010
A Canadian study that tracked 207 patients suggests that a low-dose combination of metformin and Avandia can reduce the development of type 2 diabetes by 66 percent in people at high risk for the condition.
0 comments - Posted Jun 15, 2010
One of the most inspiring personalities of the 2010 Vancouver Games, Olympic cross-country skier Kris Freeman sheds his skis and poles this week to kick off his 6th annual diabetes summer camp tour with Eli Lilly and Company (Lilly Diabetes). Freeman, diagnosed with type 1 diabetes 10 years ago at age 19, will share his amazing comeback story from coast to coast and encourage children with diabetes to continue pursuing their dreams.
0 comments - Posted Jun 14, 2010
New guidelines from the American Diabetes Association and two other major medical associations advise not prescribing low-dose aspirin therapy for women under 60 or men under 50 who have diabetes but no other risks for heart disease.
0 comments - Posted Jun 12, 2010
I am that mom. The one who buys organic foods, bakes her own bread, bans high fructose corn syrup and trans fats, and always totes around healthy snacks. I don't drink soda, my toddler has never consumed fish sticks, and not once since her birth have we visited McDonalds for a "value" or Happy Meal.
0 comments - Posted Jun 10, 2010
BD (Becton, Dickinson and Company), a leading global medical technology company, announced today the launch of BD Ultra-FineTM Nano-the world's smallest pen needle. The BD Nano pen needle is proven to be as effective as longer needles for patients of all body types and proven to offer a less painful injection experience for the more than 5 million people in the United States who inject insulin or GLP-1 to manage their diabetes.[1]
0 comments - Posted Jun 10, 2010
We all know that certain chemicals in everyday products are harmful: mercury and lead, just to name a couple. But how harmful, and what can we do about it?
0 comments - Posted Jun 9, 2010
It's a cool Sunday evening, and I'm sitting in a lively Italian restaurant. My husband is across the table. We've just placed our orders, and we're engaged in easy conversation.
0 comments - Posted Jun 8, 2010
Results from a Phase 3 study demonstrate MACUGEN® (pegaptanib sodium) significantly improved vision in patients with diabetic macular edema (DME), a complication of diabetes that is a leading cause of blindness in people of working age.¹ In the study, 37 percent of patients treated with MACUGEN gained two lines, or 10 letters, of vision on the ETDRS eye chart at 54 weeks, compared to 20 percent of patients who received a sham (placebo-like) procedure which consists of anesthesia and a simulated injection in the eye (p=0.0047). The data were presented at the World Ophthalmology Congress in Berlin by Frank G. Holz, an investigator in the trial and director of the University Eye Hospital at the University of Bonn in Germany.
0 comments - Posted Jun 7, 2010
If you take metformin to control your type 2 diabetes, ask your doctor to take a look at your vitamin B-12 levels when you get a chance. A recent British study shows that metformin may cause a deficiency in the vitamin, which is necessary for the regeneration of red blood cells and the maintenance of nervous system health.
0 comments - Posted Jun 5, 2010
With the rise of the iPhone and the creation of hundreds of thousands of iPhone applications, it's only natural that several wonderful apps have appeared to make life easier for diabetes patients. Here is a quick look at 10 FREE applications, in no particular order, to help you choose the right ones for you.
1 comment - Posted Jun 2, 2010
It's early on a Thursday morning in a hotel ballroom in downtown Oakland, and attendees at a breakfast of the annual meeting of the California Dietetic Association are still working on getting fully awake. That problem is solved two minutes after Jay Hewitt, the breakfast's inspirational speaker, takes the stage. Hewitt, a 41-year-old lawyer who was diagnosed with type 1 in 1991, knows his audience is an experienced group of professional dietitians that has dealt with every type of patient and heard every kind of excuse for failure.
0 comments - Posted Jun 1, 2010
May 2010
Both genetic components and environmental factors play a role in most chronic diseases, including type 2 diabetes. In the same way that researchers use a Genome-Wide Association Study (GWAS) to evaluate the role of genetic factors in disease, scientists at Stanford University have used an Environmental-Wide Association Study (EWAS) to evaluate environmental factors on diabetes.
0 comments - Posted May 29, 2010
It was a great win for diabetes on Sunday night as Bret Michaels, lead singer for the rock band Poison and reality TV star, was crowned the latest Celebrity Apprentice winner after struggling with several medical scares in the past month. Just as impressive is that throughout the season, Michaels' various wins raised more than $390,000 for the American Diabetes Association, including the final challenge prize from Snapple, worth $250,000. The 47-year old Michaels has lived with type 1 diabetes since he was six years old.
0 comments - Posted May 29, 2010
Abbott announced that it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its new FreeStyle Lite blood glucose test strips. The new FreeStyle Lite test strips minimize interference during blood glucose testing and are designed to offer a better testing experience.
0 comments - Posted May 27, 2010
As awareness of pre-diabetes grows, the list of conditions that can lead to it seems to be growing. Along with obesity and a sedentary lifestyle, researchers may start listing lack of sleep as another danger signal. Two recently published studies conclude that sleep deprivation can lead to insulin resistance-a precursor for diabetes-and even increase the risk of early death.
0 comments - Posted May 26, 2010
A Seattle-based study has found that people with diabetes run a 40 percent increased risk of developing a common type of abnormal heart rhythm known as atrial fibrillation*. The study also shows that as people with diabetes take drugs for the disease, their risk for developing atrial fibrillation increases three percent for each year that they use such medications.
0 comments - Posted May 25, 2010
The 57 million Americans currently living with "pre-diabetes" could benefit from a group weight loss program, like Weight Watchers, according to a new study published in this month's American Journal of Lifestyle Medicine. Researchers found that after a 6-month Weight Watchers group program, overweight or obese adults who attended at least two thirds of the weekly sessions, not only lost weight, but also significantly reduced fasting glucose and insulin levels - important indicators of diabetes risk.
0 comments - Posted May 22, 2010
People with diabetes who have limited health literacy are at higher risk for hypoglycemia or low blood sugar, according to a new study from researchers at the University of California, San Francisco and the Kaiser Permanente Division of Research in Oakland, CA.
0 comments - Posted May 20, 2010
A new study released by the Children's Hospital of New Orleans has found that black children with type 1 diabetes scored higher on A1c tests than white children who had similar blood glucose levels. Such ethnic disparity has already been shown in previous studies with adults.
0 comments - Posted May 18, 2010
The International Diabetes Federation (IDF) has kicked off its World Diabetes Day campaign under the slogan "Let's take control of diabetes. Now." Led by the International Diabetes Federation and its member associations, World Diabetes Day is celebrated every year on November 14. Created in 1991 by IDF and the World Health Organization (WHO) in response to growing concerns about the escalating threat of diabetes worldwide, it reaches a global audience of over 1 billion people. World Diabetes Day became an official United Nations Day in 2007.
0 comments - Posted May 18, 2010
Phil Southerland was diagnosed with Type 1 diabetes when he was seven months old. Now 28, he has always taken an aggressive approach to managing the disease. He recalls, "My mom scared the daylights out of me when I was six years old by letting me know about the severe complications of diabetes if you don't take care of it. That has motivated me to never let those complications fall on my shoulders."
0 comments - Posted May 17, 2010
Rhode Island-based CVS/pharmacy, which operates more than 7,000 pharmacies and drug stores in the United States, has announced three diabetes-related initiatives:
0 comments - Posted May 15, 2010
Over 80 years ago, famed diabetologist Elliot Joslin said about the treatment of patients with type 1 diabetes: "Ketoacidosis may kill a patient, but frequent hypoglycemic reactions will ruin him." Unfortunately, hypoglycemia continues to be the most difficult problem facing most patients, families, and caregivers who deal with the management of type 1 diabetes on a daily basis. Frequent hypoglycemia episodes not only can "ruin," or adversely impact the quality of life for patients, but also, when severe, can cause seizures, coma, and even death.
10 comments - Posted May 13, 2010
The Food and Drug Administration (FDA) has launched a "Bad Ad Program," an outreach effort aimed at educating healthcare providers and urging them to report misleading drug advertisements. The Division of Drug Marketing, Advertising, and Communications (DDMAC), in the FDA's Center for Drug Evaluation and Research, administers the program.
0 comments - Posted May 13, 2010
Dr. Richard Hays announced today that he is now recruiting children with newly diagnosed type 1 diabetes for Protégé Encore, a randomized, placebo-controlled Phase III clinical trial. This is the second of two Phase III studies testing the safety and efficacy of an investigational drug called teplizumab. The first study, known as Protégé, has completed enrollment of more than 530 subjects with type 1 diabetes. There is currently no approved therapy to slow the progression of type 1 diabetes.
0 comments - Posted May 12, 2010
Scientists at the Mayo Clinic have developed a molecule that can block the breakdown of insulin. Their discovery could lead to development of a new class of drugs to help treat diabetes.
0 comments - Posted May 10, 2010
I woke up on the floor of my living room, soaked in sweat. I could not stand, or even sit up. I could not raise my arms or control my hands enough to grasp anything. Forget reaching for the telephone, even if my brain could have formulated the thought to try. I could not speak, but I lived alone, so there was no one to hear anyway. I did not know what day it was, but the hot July 4th late afternoon sun was shining brightly through the windows. After an unknown period of time, my brain must have had a flash of coherence that I was having severe hypoglycemia.
8 comments - Posted May 8, 2010
Osiris Therapeutics announced that it has been granted Orphan Drug designation from the U.S. Food and Drug Administration (FDA) for Prochymal as a treatment for type 1 diabetes mellitus. The FDA instituted the Orphan Drug Act to promote the development of treatments for underserved patient populations. To be eligible for Orphan Drug designation, the treatment must target a disease that affects fewer than 200,000 new patients per year in the United States.
0 comments - Posted May 7, 2010
A new study to be published in the June issue of the Journal of Clinical Endocrinology & Metabolism (JCEM) says that a single night of too little sleep can induce insulin resistance.
2 comments - Posted May 6, 2010
My last ten tips were meant to give you an idea of what to think about before you plan your day (Tyler's Top Ten Tips). Now I'm going to give you my top ten tips for how to manage your blood glucose levels while playing sports. These should help you keep everything in control and allow you to relax and have fun while playing.
4 comments - Posted May 5, 2010
CINCINNATI - The popular diabetes medication metformin works in different fashion than the current widely accepted view. This new finding could lead to wider use of the drug-particularly in people with cancer.
1 comment - Posted May 4, 2010
April 2010
Are you the parent of a child with type 1 diabetes? Do you often wish that you could find a babysitter who understands the "ins-and-outs" of type 1 so that you could enjoy an evening out, assured that your child is in good hands? Or are you a teenager with type 1 who is looking for a way to help children manage their disease, while making a little extra money at the same time? Then look no further than www.SafeSittings.com. Launched over six years ago in Manhattan by teenager Kimberly Ross, www.SafeSittings.com is a free online service that matches type 1 families with babysitters who also have the disease.
4 comments - Posted Apr 30, 2010
NEW YORK, April 27, 2010 - The Juvenile Diabetes Research Foundation announced today that it is partnering with Living Cell Technologies (LCT), a New Zealand-based biotechnology company focused on developing cell based therapeutics, in a Phase II clinical trial to study the safety and effectiveness of transplanting encapsulated insulin-producing cells from pigs as a treatment for type 1 diabetes with significant hypoglycemia unawareness.
1 comment - Posted Apr 28, 2010
Last week the U.S. Food and Drug Administration announced an initiative to evaluate safety problems that may occur with external infusion pumps. These devices are used to deliver fluids or medications to patients in a controlled manner. Insulin pumps, for example, release insulin into the body at a controlled rate to compensate for a lack of insulin production in people with type 1 diabetes.
8 comments - Posted Apr 27, 2010
Dear Diabetes Health, I am a 60 year old married woman who was diagnosed with type 2 diabetes eight years ago. In the last two years, I have lost interest in sex. I just don't feel like it, although I still like hugs.
3 comments - Posted Apr 26, 2010
A team of researchers from Case Western University published an article revealing their invention of a "smart" insulin molecule that binds considerably less to cancer receptors and self-assembles under the skin. To provide a slow-release form of insulin, the compound self-assembles under the skin by "stapling" itself together with zinc ions. Zinc staples connect the pieces of the insulin puzzle together to create a functional protein.
0 comments - Posted Apr 23, 2010
In the early hours of Saturday, February 27th, an 8.8-magnitude earthquake hit Chile, eventually leaving 1.5 million displaced from their homes. At 6 a.m. that same morning, Hawaiians awoke to the news that a tsunami was barreling towards them and evacuation was necessary. Within minutes, many had left their homes for safe ground.
0 comments - Posted Apr 23, 2010
The study, published in the journal Diabetes Care, adds to evidence that metformin, a generically available drug commonly used for type 2 diabetes, may have anti-cancer effects.
0 comments - Posted Apr 22, 2010
Admit it, Type 1s. In weaker moments, you look down your noses at the Type 2 diabetics. You know that their disease can result from poor lifestyle choices. You know that their treatment regimen, compared with yours, is simple.
35 comments - Posted Apr 19, 2010
The first human trials of the latest design of an artificial pancreas for people with type 1 diabetes found the device worked without causing low blood sugar (hypoglycemia).
8 comments - Posted Apr 18, 2010
Roche and Elron Electronics Ltd. announced that they have signed an agreement under which Roche will acquire 100% of Medingo Ltd., a majority-owned subsidiary of the Elron group. Medingo Ltd. is engaged in the development of a semi-disposable insulin patch pump (Solo MicroPump). Under the terms of the agreement, Roche will pay Medingo Ltd.'s shareholders an upfront payment of US$ 160 million as well as up to 25% of the upfront payment in performance related milestones.
5 comments - Posted Apr 14, 2010
Healthy, insulin-producing beta cells in the pancreas have a relatively long life and typically do not replicate under normal conditions. Any loss of beta cells, therefore, is usually permanent. In the case of type 1 diabetes, for example, the destruction of beta cells by the body's own immune system is permanent.
2 comments - Posted Apr 9, 2010
Using a sophisticated nanotechnology-based "vaccine," researchers were able to successfully reverse type 1 diabetes in mice and slow the onset of the disease in mice at risk for the disease. The study, co-funded by the Juvenile Diabetes Research Foundation, provides new and important insights into understanding how to stop the immune attack that causes type 1 diabetes, and could even have implications for other autoimmune diseases.
2 comments - Posted Apr 9, 2010
Tests of an experimental drug called CPSI-1306 at Ohio State University were so successful at lowering inflammation and blood sugar levels in lab mice with type 2 diabetes that scientists consider it a prime candidate to become a new therapy for the disease.
0 comments - Posted Apr 8, 2010
(Reuters Health) - Adding soy supplements to the diet may not improve blood sugar control in older women who are at high risk of or in the early stages of type 2 diabetes, a new study suggests.
0 comments - Posted Apr 7, 2010
Most people who have pre-diabetes know that exercise is a key element in successfully avoiding full-on diabetes. But lack of time-either for real or as an excuse-often gets in the way.
2 comments - Posted Apr 6, 2010
While the words "diabetes" and "camp" may not sound like they belong in the same sentence for most people, they sure do for thousands of kids across the country. Diabetes camp is their time to share experiences, learn, and have fun with other kids who have diabetes. You'll find the usual camping activities like hiking, arts and crafts, boating, swimming, and sitting around the campfire, but also lessons on adjusting your insulin pump to compensate for sports and how to give yourself an injection.
0 comments - Posted Apr 1, 2010
March 2010
Dr. Stan De Loach is a bicultural, trilingual, Certified Diabetes Educator (one of the first 13 in Mexico) and clinical psychologist, not to mention a pianist, composer, and writer. Born and educated in the U.S., he has been a resident of Mexico for decades, and his first love is the annual bilingual diabetes camp that he co-founded, the four-day Campamento Diabetes Safari in Mexico..
3 comments - Posted Mar 30, 2010
The U.S. Food and Drug Administration has withheld approval of Bydureon, the once-weekly version of the popular type 2 diabetes drug Byetta. The agency has asked its manufacturer, Amylin, for more information regarding Bydureon's manufacture, labeling, and risk management plan. It did not, however, request further information on tests of the drug itself-an indication that the agency probably intends to grant marketing permission once it has dotted all the i's and crossed all the t's involved in the approval process.
0 comments - Posted Mar 29, 2010
A University of Texas researcher who genetically modified mice with type 1 diabetes to control their disease with leptin instead of insulin is now ready to extend his experiment to human test subjects. Dr. Roger Unger, a researcher at the UT Southwestern Medical School in Dallas, will begin the tests as soon as leptin manufacturers can assure him of a steady supply of the hormone.
2 comments - Posted Mar 27, 2010
According to researchers at the Emory University School of Medicine, obesity and metabolic syndrome may be partially brought on by intestinal bacteria that increase appetite and insulin resistance. The two can lead to overeating and high blood sugar levels - both important factors in the eventual onset of type 2 diabetes. Perhaps even more interesting, the scientists found that the bacteria can be transferred from one mouse to another, creating increased appetite and insulin resistance in an animal that had previously experienced neither.
0 comments - Posted Mar 26, 2010
Suggested revisions in the benchmarks used to assess dangerously high blood sugar levels in pregnant women could lead to a doubling or tripling of the number of women diagnosed with gestational diabetes*. That's the conclusion of an international study led by the Northwestern University Feinberg School of Medicine in Chicago.
0 comments - Posted Mar 24, 2010
You may not have heard of GAD, but it's a hot topic in the world of type 1 diabetes research. GAD, which stands for glutamic acid decarboxylase, is an enzyme in the brain and the pancreas that plays several roles in the body. As an enzyme, it converts the excitatory amino acid glutamate into the inhibitory neurotransmitter GABA, which nerve cells use to communicate. But it also has a less helpful role, as an autoantigen (an element of self that provokes the generation of antibodies) in autoimmune diabetes.
4 comments - Posted Mar 23, 2010
MINNEAPOLIS - March 17, 2010 - Medtronic, Inc. today announced it has received U.S. Food and Drug Administration (FDA) approval for the MiniMed Paradigm® REAL-Time RevelTM System, the next generation of the industry's only integrated diabetes management system (insulin pump therapy, continuous glucose monitoring (CGM) and diabetes therapy management software). The system incorporates new innovative CGM features including predictive alerts that can give early warning to people with diabetes so they can take action to prevent dangerous high or low glucose events.
3 comments - Posted Mar 22, 2010
I grew up around the corner from the National Institutes of Health (NIH). In high school, long ago, I thought that NIH scientists were "bad guys" who mistreated animals in the name of medical research. I later moved to the West Coast and became a registered obstetrical nurse. Over the years, along with sharing the joys of new moms and new babies, I cared for patients with devastating conditions like cancer and quadriplegia, people whose lives could potentially be saved or improved by medical research., Yet it wasn't until many years later, after moving back to the DC area, that I really began to see the NIH in a new light.
4 comments - Posted Mar 20, 2010
According to Duke University researchers, a mutation that causes the lack of an insulin-controlling molecule may be a factor in the development of type 2 diabetes. The molecule, ankyrin B, is activated in response to the smell and taste of food and leads to the production of insulin in preparation for food intake.
1 comment - Posted Mar 19, 2010
At a two-day meeting (March 16 and 17, 2010) to review blood glucose meters, Food and Drug Administration officials and staff pointed to a number of issues that can prevent people from getting proper treatment and sought input from medical experts and industry on ways to improve test results with the widely used devices.
1 comment - Posted Mar 18, 2010
Dear Diabetes Health, I am a 55-year-old man who was diagnosed with type 2 diabetes two years ago, and I think it made me depressed. The depression eventually got so bad that I didn't want to get out of bed in the morning. My doctor referred me to the psych clinic, where they put me on Paxil (paroxetine). The medication is helping my depression, but ruining my sex life. Basically, I can't get an erection, but I don't really care because I'm not interested anyway. I have no desire. My wife is still interested, however, and she is really upset about my lack of desire for sex. I don't like hurting her, and I don't want us to break up over this, but the depression was awful. I don't want to go back to that. What can I do?
4 comments - Posted Mar 16, 2010
Allen, Texas - When Pam Henry's daughter was diagnosed with type 1 diabetes in 2003, she never even thought she would be part of something that could revolutionize health care. "When Sarah was diagnosed, my only goal was to do all I could to keep her as healthy as possible. What I created was something just to help keep her that way."
4 comments - Posted Mar 13, 2010
The sooner people with diabetes start taking metformin, the longer the drug remains effective, according to a Kaiser Permanente study published in the March issue of Diabetes Care, a journal of the American Diabetes Association.
2 comments - Posted Mar 12, 2010
Santa Clara County, the largest county in Northern California (nearly 1.9 million people), has filed a federal lawsuit against pharmaceutical company GlaxoSmithKline, alleging that Glaxo knowingly sold its type 2 diabetes drug Avandia for several years despite indications the drug causes heart attacks and strokes.
0 comments - Posted Mar 9, 2010
The benefits of using insulin to treat diabetes far outweigh the risks, but a review just published online by IJCP, the International Journal of Clinical Practice, suggests that commonly used diabetes therapies may differ from each other when it comes to their influence on cancer risk.
1 comment - Posted Mar 5, 2010
If you regularly take metformin, one of the oldest and most respected tools in doctors' anti-diabetes kits, chances are that you don't detect the unpleasant odor that turns some type 2s against the drug. Some think it has fishy smell, while others say that it reminds them of the inside of an inner tube.
10 comments - Posted Mar 4, 2010
Amylin Pharmaceuticals has announced that it expects to begin selling a once-weekly version of its diabetes drug, Byetta, by the end of the year. The company reports that the FDA is nearing final inspections of its manufacturing plant and could give the go-ahead for U.S. sales in early March.
2 comments - Posted Mar 4, 2010
The demand for diabetes research funding clearly exceeds the funds available. In the United States, 23.6 million children and adults (7.8 percent of the population) have diabetes, and we spent $174 billion on diagnosed diabetes alone in 2007 (the most recent year for which data are available). It is imperative that we take action, but where is the research funding coming from? Can it possibly be sufficient, and how is it being spent?
1 comment - Posted Mar 3, 2010
When I was undiagnosed and sick, I was very angry with God. I didn't understand why I was weak, fatigued, constantly thirsty and hungry, scarily thin, and mentally foggy. I prayed and prayed for an answer. I cried, I cursed, and I yelled. Nothing. For a year and a half. When I received my diagnosis in a local emergency room, I felt instant relief. Finally, I had an answer, a name, and some hope. But soon after, the anger reappeared, this time because God had failed to pass over me. I had done nothing to earn this fate. Why me?
18 comments - Posted Mar 2, 2010
An enzyme that destroys pancreatic beta cells in lab mice has now been observed in human beta cells. Because scientists already know how to delete the mouse gene that produces the enzyme, they are hopeful that the same therapy can eventually be applied to people with type 1 diabetes. If so, it would be one of the most powerful therapies yet for addressing the destruction of insulin-producing beta cells that causes type 1.
4 comments - Posted Mar 1, 2010
February 2010
Danish pharmaceutical company Novo Nordisk has received Food and Drug Administration permission to begin marketing its type 2 drug Victoza® in the United States.
Victoza, the brand name for liraglutide, is a GLP-1* analog that is taken one a day by injection to help control blood sugar-and in some cases, help with weight loss-in patients with type 2 diabetes.
5 comments - Posted Feb 27, 2010
My four-year-diabetes-diagnosis anniversary is almost here. It falls on March 24th, a day just like any other to most people, but a day full of sadness, loss, and victory for me. Will I celebrate? I'm not sure if reflection is a form of celebration. I'd much prefer a birthday-like affair featuring balloons, cards, and, of course, something sweet to eat. But I also feel as if the impending date is much like a funeral on the calendar, a time for mourning as well as reflection.
28 comments - Posted Feb 26, 2010
As part of an extensive program to support the needs of adults with type 1 diabetes, the Juvenile Diabetes Research Foundation International announced the introduction of a key support program, the JDRF Adult Type 1 Toolkit, to meet an immediate need for resources and community for adults more recently diagnosed with type 1 diabetes - a chronic autoimmune disease often first diagnosed in children.
3 comments - Posted Feb 24, 2010
The Staff Report of the Senate Committee on Finance draws conclusions on the safety of Avandia (rosiglitazone) that are based on analyses that are not consistent with the rigorous scientific evidence supporting the safety of the drug. In addition, the report cherry-picks information from documents, which mischaracterizes GlaxoSmithKline's comprehensive efforts to research Avandia and communicate those findings to regulators, physicians and patients. In fact, the safety and effectiveness of Avandia is well characterized in the label approved by the FDA.
1 comment - Posted Feb 23, 2010
A hormone responsible for the body's stress response is also linked to the growth of insulin-producing cells in the pancreas, according to JDRF- funded researchers at the Salk Institute for Biological Studies in California. The findings are the latest advances to underscore the potential for regeneration as a key component of a possible cure for type 1 diabetes.
2 comments - Posted Feb 22, 2010
A U.S. Senate Finance Committee report released on February 20 says that Avandia, GlaxoSmithKline's drug for type 2 diabetes, may have caused as many as 83,000 heart attacks between 1999, when the drug was introduced, and 2007. The Senate report, culminating a two-year inquiry into the drug, also says that Glaxo knew about the drug's potential risks years before suspicions began to form regarding a connection between Avandia and heart problems.
2 comments - Posted Feb 22, 2010
This is the third - and final - installment of our three-part series "Handing Down the Genes." Part III: "Nutrition and Exercise Tips"
1 comment - Posted Feb 19, 2010
Feb. 11, 2010 - At the 3rd International Conference on Advanced Technologies and Treatments for Diabetes (ATTD) in Basel, Switzerland, Roche Diabetes Care, the University of California Santa Barbara (UCSB), and Sansum Diabetes Research Institute announced their expanded collaboration in the Artificial Pancreas Project sponsored by the Juvenile Diabetes Research Foundation (JDRF).
3 comments - Posted Feb 18, 2010
A university study says that aerobic exercise, a known means of increasing insulin sensitivity, is most effective if the meals following it are low in carbohydrates. The study also revealed that consuming a low-calorie meal after exercising does not increase insulin sensitivity any better than eating a low-carb meal after a workout. In addition, it found that the beneficial effects of exercise are immediate and do not build up over time or last very long. Improvements in metabolism, including insulin sensitivity and lowered blood pressure, occur directly as a result of the latest exercise session, but taper off within hours or days. There is no "storing up" the benefits of exercise.
3 comments - Posted Feb 17, 2010
This is the second installment of our three-part series "Handing Down the Genes." Part II: "Preventing Type 2 in Children"
1 comment - Posted Feb 13, 2010
Sacramento- February 10, 2010 -- Assistant Speaker pro Tempore Isadore Hall, III (D- Compton) today introduced AB 1802, which would clarify existing law by allowing, but not requiring, a parent/guardian-designated teacher, administrator or school employee to administer insulin to a diabetic student while on a school campus.
3 comments - Posted Feb 11, 2010
Results of a 22-year study by researchers at Cardiff University School of Medicine in Wales indicate that older type 2s who try too hard to drive their A1c's down to "normal" (4.5% to 6%) may significantly increase their chances of early death. In fact, the study, just published in the British medical journal The Lancet*, found that type 2s with the lowest risk of death had A1c's of 7.5% -- a figure that few authorities on the disease have recommended as ideal.
15 comments - Posted Feb 11, 2010
A California study that tracked 77 obese adolescents for almost two years indicates that metformin XR, an extended-release version of the popular anti-diabetic drug, may help lower body mass index in overweight teens who do not have diabetes.
1 comment - Posted Feb 10, 2010
Researchers at RIKEN and Fukuoka University have pinpointed the mechanism responsible for early rejection of transplanted pancreatic islet cells in the treatment of type 1 diabetes. A new system based on this mechanism has been shown to vastly increase transplant efficiency, setting the stage for the development of powerful new treatment techniques.
5 comments - Posted Feb 9, 2010
Steel-cut oats are whole grains, made when the groats (the inner portion of the oat kernel) are cut into pieces by steel. Also known as coarse-cut oats or Irish oats, they are golden and look a little like small pieces of rice. They gain part of their distinctive flavor from the roasting process after being harvested and cleaned. Although the oats are then hulled, this process does not strip away their bran and germ, allowing them to retain a concentrated source of their fiber and nutrients.
4 comments - Posted Feb 9, 2010
Dear Diabetes Health, I'm 26 years old and engaged to a woman I've known since college. We live together, love each other, and have good sex, but now I'm having doubts. A year ago, she was diagnosed with type 1 diabetes. She started taking insulin, and it has been rough. Four times now she has started sweating and shaking and saying strange things. Twice this happened during sex.
11 comments - Posted Feb 3, 2010
Depression raises risks of advanced and severe complications from diabetes, according to a prospective study of Group Health primary-care patients in western Washington. These complications include kidney failure or blindness, the result of small vessel damage, as well as major vessel problems leading to heart attack or stroke.
3 comments - Posted Feb 2, 2010
Denmark-based Novo Nordisk has begun a Phase 1 trial of a pill form of a GLP-1 drug very similar to its Victoza product. The trial will involve 155 British patients with type 2 diabetes. The test on human subjects, although very early-stage, puts the company in the lead to develop an oral form of a GLP-1 drug.
0 comments - Posted Feb 1, 2010
January 2010
On Monday, take a look at our new Feb\March digital edition. DiabetesHealth sat down to talk with Kris Freeman, the first Olympian with type 1 diabetes to compete in the endurance sport of cross country skiing. He has shared his story about what it is like to follow your dreams regardless of the obstacles in place. Working with Eli Lily, Kris spends time traveling around the country talking with kids about their aspirations and diabetes. He wants his story to inspire other people with type 1 diabetes to follow their own dreams. "Diabetes doesn't have to hold you back."
0 comments - Posted Jan 30, 2010
Thousands of elite athletes from around the world are making their final preparations for the 2010 Winter Olympics in Vancouver, British Columbia. Every snowboarder, short track speed skater, ski jumper and hockey player shares a dream of standing on the medium wearing an Olympic gold medal.
7 comments - Posted Jan 29, 2010
Altruism is unselfish concern for the welfare of others. It is a traditional virtue in many cultures, and a core aspect of various religious traditions such as Judaism, Christianity, Islam, Hinduism, and Buddhism among others.
0 comments - Posted Jan 29, 2010
Novo Nordisk announced that the U.S. Food and Drug Administration (FDA) approved the new drug application for Victoza (liraglutide injection), the first once-daily human glucagon-like peptide-1 (GLP-1) analog for the treatment of type 2 diabetes. Victoza is indicated as an adjunct to diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.
4 comments - Posted Jan 28, 2010
Researchers at Sansum Diabetes Research Institute and University of California, Santa Barbara have concluded that changing the height of a conventional insulin pump in relation to its tubing and infusion set can significantly impact expected insulin delivery rates. Such changes can occur during routine daily activities like dressing, sleeping or showering. The study, "Siphon Effects of Continuous Subcutaneous Insulin Infusion Pump Delivery Performance," evaluated the siphon or hydrostatic pressure action effects on continuous subcutaneous insulin infusion and was published in the January issue of Journal of Diabetes Science and Technology.
11 comments - Posted Jan 27, 2010
An international research consortium has found 13 new genetic variants that influence blood glucose regulation, insulin resistance, and the function of insulin-secreting beta cells in populations of European descent. Five of the newly discovered variants increase the risk of developing type 2 diabetes, the most common form of diabetes.
2 comments - Posted Jan 23, 2010
The Juvenile Diabetes Research Foundation (JDRF) and BD (Becton, Dickinson and Company) announced today an innovative program aimed at improving the treatment of type 1 diabetes by developing novel insulin delivery products to enhance the use of insulin pumps.
0 comments - Posted Jan 22, 2010
Living with a chronic condition like diabetes can be a challenging and stressful experience. Unfortunately, all the worry about blood glucose and the constant effort to balance insulin against food intake and exercise can itself raise blood glucose levels. But stress management can help control the stress hormones that affect blood glucose levels. Yoga practice, for example, can have a calming effect and play a major role in stress management.
1 comment - Posted Jan 21, 2010
NEW YORK (Reuters Health) - Diabetes may hasten progression to dementia in older people with mild thinking impairment, new research shows.
2 comments - Posted Jan 19, 2010
Many meaningful events, experiences, and accomplishments have gone into making me the person that I am today. In my life, most of the important milestones came and went as they do for every kid. But for some of us, life throws a curveball and introduces a trauma or an unexpected event that will forever change our lives. When my most meaningful event occurred, on May 22, 2000, there were no cheers, applause, or laughter in the room. That was the day I was diagnosed with type 1 diabetes.
21 comments - Posted Jan 19, 2010
NEW YORK, Jan. 14 /PRNewswire-USNewswire/ -- Montefiore Medical Center continues to expand its portfolio of options for patients in need of organ transplantation. The new Pancreas Transplant Program will treat patients with severe, end-stage diabetes. As the only Pancreas Transplant Program in the Bronx and Westchester, and one of only several in Greater New York, patients will be able to receive world-class care close to home. The program currently has nine patients medically approved and waiting for a pancreas transplant.
2 comments - Posted Jan 16, 2010
NEW YORK, January 13, 2010 - The Juvenile Diabetes Research Foundation today announced an innovative partnership with Animas Corporation to develop an automated system to help people with type 1 diabetes better control their disease - the first step on the path to what would be among the most revolutionary advancements in treating type 1 diabetes: the development of an artificial pancreas, a fully automated system to dispense insulin to patients based on real-time changes in blood sugar levels.
9 comments - Posted Jan 15, 2010
One potential avenue for the treatment for type 1 diabetes is to transplant insulin-producing islet cells into the body. The Edmonton Protocol is a method of implanting pancreatic islets into the liver for the treatment of type 1 diabetes. The protocol is named for the islet transplantation group at the University of Alberta in Edmonton, Canada, where the protocol was first devised in the late 1990s.
3 comments - Posted Jan 13, 2010
German and Swiss researchers have found that high-density lipoprotein, or HDL-so-called "good" cholesterol-does not protect blood vessels in people with type 2 diabetes as well as it does in people who don't have the disease. However, their follow-up experiment, which added doses of extended-release niacin, shows that HDL's efficacy in type 2s might be sharply increased simply by the addition of a daily niacin pill.
0 comments - Posted Jan 9, 2010
BEDFORD, Mass. and BURGDORF, Switzerland, Jan. 5 /PRNewswire-FirstCall/ -- Insulet Corporation (Nasdaq: PODD), the leader in tubing-free insulin pump technology with its OmniPod® Insulin Management System, and Ypsomed AG (SIX Swiss Exchange: YPSN), a leading independent diabetes specialist and technology provider of innovative injection systems for self-medication in Europe, today announced an exclusive agreement for the distribution of the OmniPod Insulin Management System in nine countries across Europe, as well as China and Australia.
0 comments - Posted Jan 7, 2010
The first time that my fiancé Richard and I got, um, "intimate," I had some explaining to do. "Er, that's for my diabetes. So's that. And this thing. Oh, and this too." Richard was a bit overwhelmed. I think his exact words were, "Are you bionic or something?"
2 comments - Posted Jan 6, 2010
"You have diabetes." Have you just heard these words? Or maybe you recently heard it about your son or daughter. The oxygen rushes out of your body. A knot forms in your stomach. "What now?"
11 comments - Posted Jan 4, 2010
ROSEMONT, IL - Exercise is a critical piece of a healthy lifestyle, however those who suffer from diabetes may see an even greater impact, according to a study published in the January/February 2010 issue of Sports Health: A Multidisciplinary Approach. Authors confirm that exercise can aid in diabetes treatment by improving glucose metabolism and insulin sensitivity.
1 comment - Posted Jan 4, 2010
December 2009
December 29, 2009 - The American Diabetes Association (ADA) revised clinical practice recommendations for diabetes diagnosis promote hemoglobin A1c (A1c) as a faster, easier diagnostic test that could help reduce the number of undiagnosed patients and better identify patients with prediabetes. The new recommendations are published December 29 in the January supplement of Diabetes Care.
2 comments - Posted Dec 31, 2009
BOSTON, Mass. - Dec. 23, 2009 - Cells in your body are constantly churning out poisonous forms of oxygen (oxidants) and mopping them up with a countervailing force of proteins and chemicals (anti-oxidants). This balancing act of oxidative stress is particularly likely to go haywire in beta cells, the insulin-producing cells that malfunction and then start to die off in type 2 diabetes.
2 comments - Posted Dec 29, 2009
As an American living abroad, I tried to follow the debate over healthcare reform in the US, but I had to drop it for my own sanity. How could so many of my fellow Americans say that people like me, with chronic diseases we never asked for, should pay more for healthcare because they don't want to participate in the risk pool? How could people like me, who live in fear of losing health insurance, be blind to how badly Americans with type 1 diabetes can get ripped off? I had to remind myself, "It's okay. I don't live there anymore."
14 comments - Posted Dec 29, 2009
BOSTON/NEW YORK, Dec 23 (Reuters) - The shares of Amylin Pharmaceuticals Inc (AMLN.O) fell nearly 10 percent on Wednesday after the U.S. Food and Drug Administration requested that the company conduct additional safety studies on its diabetes drug, Byetta.
1 comment - Posted Dec 28, 2009
A 20-year study that tracked 704 women from before their first pregnancy onward suggests that the first year mothers breastfeed, they reduce their risk of acquiring type 2 diabetes within the next 15 years by 15 percent. Each subsequent year of breastfeeding further reduces the risk by 15 percent. For example, a mother who has two children and breastfeeds each for a year could enjoy a 30 percent reduction in her risk of type 2 over a 15-year period.
2 comments - Posted Dec 25, 2009
Denmark-based Novo Nordisk A/S has begun phase 1 testing of an insulin pill that, if successful, could replace injections as the primary means of blood sugar control for millions of people with type 1 and type 2 diabetes. The company has enrolled 80 volunteer German test subjects in the study and expects to have preliminary results by the first half of 2011. The test group consists of both people with diabetes and people without it.
12 comments - Posted Dec 24, 2009
Rituxamab, a drug that treats lymphoma and rheumatoid arthritis, may soon be used to help combat the destruction of pancreatic beta cells in newly diagnosed cases of type 1 diabetes. Researchers at Indiana University have found that the drug, originally developed and sold by Genentech as Rituxan, temporarily slows or stops the destruction of the 10 or 20 percent of beta cells that type 1s typically have remaining when they are first diagnosed.
0 comments - Posted Dec 21, 2009
NEW YORK, Dec. 17, 2009 - The Juvenile Diabetes Research Foundation, a leader in setting the agenda for diabetes research worldwide, said today that it will begin working with The Johnson & Johnson Corporate Office of Science and Technology, and its affiliates, to speed the development of drug targets and pathways to promote the survival and function of insulin-producing cells in people who have diabetes. The program will look to fund research at academic centers around the world that could eventually lead to novel drug targets and industry collaborations for the treatment of type 1 diabetes.
2 comments - Posted Dec 19, 2009
Good injection practices - such as proper injection technique, site rotation, and appropriate needle use - are as important to your glucose control as your type and dosage of insulin (1). But over time, you may have developed your own injection technique, which may not exactly accord with professional guidelines and standards. For instance, you might reuse your needles. It's a very common practice, despite the fact that guidelines issued by regulatory agencies call for all insulin injection needles to be labeled single-use only. However, changes to injection technique can alter insulin absorption and may lead to problems down the road. So maybe it's time for a refresher in the official line on appropriate insulin injection practices - injection technique, site rotation, and proper needle use (2).
7 comments - Posted Dec 18, 2009
‘Tis the season to be jolly? The most wonderful time of the year? Joy to the world? Between Black Friday, meal preparations, decorating, dealing with clashing family members, and party after party, the holiday season can be one of the most stressful times of the year. The joy and jolly that we sing about in Christmas carols hardly resonates in our lives as we prepare for and then attempt to survive the stress of the holidays.
3 comments - Posted Dec 17, 2009
WASHINGTON, Dec. 15 /PRNewswire-USNewswire/ -- A 21-year old Airman severely wounded in Afghanistan is recovering at Walter Reed Army Medical Center after several surgeries and an unprecedented transplant.
2 comments - Posted Dec 17, 2009
A gene named HHEX/IDE, which has already been implicated in the development of type 2 diabetes (see research article), may also contribute to childhood obesity. While the gene does not appear to affect birth weight and does not necessarily predispose an adult to become obese, it may set the stage for obesity in some children.
0 comments - Posted Dec 16, 2009
If you have diabetes and are wondering whether you're prepared for a unexpected disaster, then head for the website of the American Association for Diabetes Educators. There you'll find a Diabetes Disaster Response Toolkit that contains an abundance of information on nearly every aspect of getting prepared and helping your local diabetes community do the same. The toolkit, which was put together by the Alamo Association of Diabetes Educators in Texas, will help any educator or member of the public get ready to handle diabetes during a flood, earthquake, or any other natural or human-made disaster.
3 comments - Posted Dec 10, 2009
Dear Diabetes Health, I am 57 years old. About five years ago, I saw my doctor because I was feeling tired. My waist size was up, and I was not interested in sex. I almost never got an erection. The doctor diagnosed type 2 diabetes and put me on metformin. He also prescribed Viagra, which helped sometimes, but not all the time.
5 comments - Posted Dec 10, 2009
WORCESTER, Mass., Dec 3, 2009 (GlobeNewswire via COMTEX News Network) -- Published in the journal Diabetes, Obesity and Metabolism, an independent review of clinical trials of Generex Oral-lyn(TM) shows that the oral insulin spray has a faster onset of action and shorter duration of action than insulin delivered subcutaneously.
6 comments - Posted Dec 9, 2009
Chevy Chase, MD- According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), youth with type 1 diabetes have now been found to have abnormal insulin resistance. Having abnormal insulin resistance appears to negatively affect heart, blood vessel and exercise function in this population.
7 comments - Posted Dec 5, 2009
The road to my diabetes diagnosis was anything but easy. Over Thanksgiving break during my first semester of graduate school, I fell ill with a horrific stomach virus. I was too busy to be sick, swamped with student essays to grade and papers to write for my own classes. But as the following year and half progressed, I felt worse and worse. I suffered from chronic sinus infections, drastic weight loss, extreme thirst, and constant fatigue. As I bounced from doctor to doctor, I grew increasingly discouraged. No one could figure out what was wrong with me.
16 comments - Posted Dec 4, 2009
A Swedish biotechnology company, TikoMed AB, has received notice that the U.S. Food and Drug Administration is granting orphan drug designation to its IBsolvMIR® drug for preventing the rejection of transplanted pancreatic islet cells in type 1 patients.
0 comments - Posted Dec 4, 2009
ALEXANDRIA, Va. (Dec. 1, 2009) - Seniors may find that many common prescription drugs that Medicare Part D has covered for years may suddenly be denied due to a new policy being implemented by the Centers for Medicare and Medicaid Services (CMS).
7 comments - Posted Dec 3, 2009
November 2009
Many autoimmune diseases, such as lupus erythematosis and type 1 diabetes, are caused by autoantibodies. An autoantibody is an antibody (a protein) produced by the immune system of an individual, which is directed against a different protein of the the same individual.
4 comments - Posted Nov 30, 2009
A study presented at the American Heart Association's 2009 Scientific Sessions said that eight percent of obese people misunderstand their body size and don't feel they need to lose weight.
3 comments - Posted Nov 30, 2009
Dr. Jennie C. Brand-Miller, from the University of Sydney stated that, "The food insulin index (FII) may provide a better way to adjust insulin dose in Type 1 diabetes.... In time, it may also enable us to design diets to prevent diabetes."
2 comments - Posted Nov 26, 2009
We hear it all the time, from the diet ads on television to the lectures from our doctors and dietitians. What matters is not only what you eat, but also how much you eat. But how can you control your portions? Is it possible to have a healthy relationship with food? How can you make sure you are full, but not stuffed? Can you keep your blood sugars under control? The answer to all these questions is yes!
1 comment - Posted Nov 24, 2009
For 2,000 years, diabetes has been recognized as a devastating and deadly disease. A Greek by the name of Aretaeus described its destructive nature in the first century AD, naming the affliction "diabetes," the Greek word for "siphon." Eugene J. Leopold, in his text "Aretaeus the Cappodacian," described Aretaeus' diagnosis: "...For fluids do not remain in the body, but use the body only as a channel through which they may flow out. Life lasts only for a time, but not very long. For they urinate with pain, and painful is the emaciation. For no essential part of the drink is absorbed by the body, while great masses of the flesh are liquefied into urine."
4 comments - Posted Nov 24, 2009
Q: How do I lower my blood sugar when it goes over 200 mg/dl? I have type 2 diabetes.
6 comments - Posted Nov 21, 2009
Bridgewater, NJ, November 19, 2009 - Sanofi-aventis U.S. announced today that GoMealsTM, a new iPhone application (app) designed to help people living with diabetes make healthy food choices, is now available for download at the iTunes App store. GoMealsTM is a food tracking tool which allows users to search thousands of foods and dishes from popular restaurants and grocery stores to easily see the nutritional content of meals and snacks.
0 comments - Posted Nov 20, 2009
PRINCETON, N.J., Nov. 19 /PRNewswire/ -- Nearly one-third of doctors surveyed said they did not have enough time and did not receive sufficient reimbursement to provide comprehensive care to their patients with diabetes, according to the results of a study of endocrinologists and primary care doctors published in American Health & Drug Benefits.
4 comments - Posted Nov 20, 2009
The body's immune system is supposed to "tolerate" itself and distinguish "self" from "non-self." Autoimmune diseases such as type 1 diabetes result from the breakdown of this system, causing immune cells to attack and destroy insulin-producing beta cells or "self." In the November issue of Nature Immunology, Brian Fife, PhD and collaborators including senior author Jeffrey Bluestone, PhD share how they have uncovered a basic process that helps control immune cell activation and tolerance.
0 comments - Posted Nov 17, 2009
WASHINGTON--(BUSINESS WIRE)--As the nation marks American Diabetes Month, HHS Secretary Kathleen Sebelius released a new report today, Preventing and Treating Diabetes: Health Insurance Reform and Diabetes in America. The report comes one day after Sebelius toured the East Manatee Family Healthcare Center in Bradenton, Fla. At the center, Sebelius met with patients and Floridians who care for people with diabetes.
2 comments - Posted Nov 12, 2009
When I was a child, my mother always said, "Think before you speak." Have you heard of this before? If not, please digest my words. If you have heard of this simple yet beneficial policy, please reconsider its merit and then implement it into your practice.
34 comments - Posted Nov 7, 2009
The American Association of Clinical Endocrinologists (AACE) and the College of Endocrinology (ACE) released online a one-page resource for physicians and healthcare providers for the management of glycemic control in type 2 diabetes.
2 comments - Posted Nov 7, 2009
MINNEAPOLIS--(BUSINESS WIRE)--Employers are signing up for a first-of-its-kind health plan by UnitedHealthcare designed to help control the escalating costs of insuring diabetic and pre-diabetic employees and their families while improving their health.
3 comments - Posted Nov 7, 2009
If you bought Vytorin® and/or Zetia® to lower your cholesterol between November 1, 2002, and September 17, 2009, you may be entitled to some money. A lawsuit against Merck & Co., Inc., Schering-Plough Corporation, Merck/Schering-Plough Pharmaceuticals, and other defendants has reached a proposed settlement in the United States District Court for the District of New Jersey. The lawsuit, according to vytorinzetiasettlement.com (the authorized website for the settlement), claims that Vytorin and Zetia "were marketed as being more effective than other anti-cholesterol drugs and were sold at higher prices, when they were no more effective than less expensive anti-cholesterol drugs". The defendants, according to the website, "deny any wrongdoing and are settling this lawsuit to avoid the costs and expenses of further litigation."
0 comments - Posted Nov 5, 2009
October 2009
San Diego, CA (October 28, 2009) - Novocell, Inc., a preclinical stage diabetes company, today announced that it will receive a Disease Team award totaling $20 million from the California Institute for Regenerative Medicine (CIRM). The Disease Team includes a group of scientists at the University of California, San Francisco (UCSF), led by Dr. Jeff Bluestone, which is contracted to receive $2.8 million. The funding will advance Novocell's development of a first in kind cellular therapy for the treatment of diabetes.
0 comments - Posted Oct 31, 2009
October 27, 2009 - Huntsville AL-Qualitest Pharmaceuticals today issued a voluntary nationwide recall of all Accusure® Insulin Syringes. The distributed syringes are of the following descriptions and NDC numbers: 28G 1/2cc, NDC 0603-6995-21;28G 1cc, NDC 0603-6996-21; 29G 1/2cc NDC 0603-6997-21, 29G 1cc, NDC 0603-6998-21, 30G 1/2cc, NDC 0603-999-21, 30G 1cc, NDC 0603-7000-21, 31G 1/2cc, NDC 0603-7001-21; and 31G 1cc, NDC 0603-7002-21. All Accusure® Insulin Syringes regardless of lot number are subject to this recall. These syringes were distributed between January 2002 and October 2009 to wholesale and retail pharmacies nationwide (including Puerto Rico). The syringes in these lots may have needles which detach from the syringe.
0 comments - Posted Oct 29, 2009
LEXINGTON, Mass., October 27, 2009 - GI Dynamics, a leader in non-surgical treatments for type 2 diabetes and obesity, today announced data which support the safety and efficacy of the EndoBarrierTM Gastrointestinal Liner for pre-surgical weight loss treatment, along with a positive effect on glucose homeostasis in morbidly obese patients with type 2 diabetes mellitus. According to the study, mean excess weight loss (EWL) achieved after 12 weeks post implantation was 19.0 % for EndoBarrier patients versus 6.9 % for control patients (p<0.002). The results of this European weight loss study were published today in the advance online publication of Annals of Surgery.
2 comments - Posted Oct 29, 2009
Montreal, Canada - 20 October 2009 - This October marks the one-year anniversary of the international launch of the ground-breaking diabetes Conversation MapTM education tools. Created by Healthy Interactions, a global leader in health education, in collaboration with the International Diabetes Federation (IDF), Eli Lilly and Company and other leading diabetes experts, the unique Conversation MapTM education tools have been implemented in 68 countries, excluding the United States, in 31 different languages in the last 365 days. To complete the global launch, redesigned diabetes Conversation MapTM education tools will be unveiled throughout Canada in January 2010, along with a new Map designed for parents and children to learn together. New tools will also be introduced to several Sub-Saharan African countries by early next year.
0 comments - Posted Oct 29, 2009
The statistics are chilling. Children born today have a one-in-three chance of developing type 2 diabetes. For Latinos, however, that risk is one-in-two.
2 comments - Posted Oct 27, 2009
A South African university pharmacologist has found that simultaneous consumption of metformin and grapefruit juice raises lactic acid to dangerous levels in rats (and conceivably in people) with type 2 diabetes. Too much acid in the blood can cause low pH levels that interfere with the body's metabolic functions. Conceivably, says Dr. Peter Owira, a pharmacologist at the University of KawZulu-Natal, such low levels could be fatal.
5 comments - Posted Oct 26, 2009
A recent and contentious meeting of diabetes experts at the European Association for the Study of Diabetes in Vienna, Austria, has continued the intense international debate over whether bariatric surgery should become a treatment for type 2 diabetes or continue to be reserved only for the extremely obese.
13 comments - Posted Oct 24, 2009
MONTREAL, Canada, 19 October 2009 - The International Diabetes Federation's 20th World Diabetes Congress opened today at the Palais de Congress in Montreal, Quebec. The five-day congress brings thousands of international delegates to the Canadian city to discuss burning issues in diabetes care and examine local, national and regional solutions to a growing global problem.
1 comment - Posted Oct 19, 2009
NEW YORK (Reuters Health) Oct 13 - Women with metabolic syndrome in early pregnancy have a higher risk for preterm birth, according to study findings reported in the October 1st issue of the American Journal of Epidemiology.
0 comments - Posted Oct 16, 2009
The National Center for Chronic Disease Prevention and Health (CDC) recommends that everyone, especially people with diabetes and other diseases, get both a seasonal flu vaccination and an H1N1 flu ("swine flu") vaccination this year.
6 comments - Posted Oct 16, 2009
"Self-monitoring blood glucose" (SMBG), a staple in the lives of most people with diabetes who take insulin, involves consistently monitoring and recording blood glucose levels before and after specific activities, such as eating, exercising, sleeping, and taking insulin. By observing the effects of certain foods and activities on their blood glucose levels, patients can learn exactly what works to raise or lower them. Thus, SMBG affords a kind of "fine tuning" approach to diabetes that empowers patients to adjust their medicine, modify their behavior, and manage their disease without always needing expert intervention.
1 comment - Posted Oct 13, 2009
A law signed by New Jersey Governor Jon Corzine that allows teachers to give emergency glucagon shots to students with diabetes has parents elated but has drawn strong opposition from teachers and nurses. The law also allows students with diabetes to test their own blood glucose levels and use insulin pumps while they are in the classroom, two activities that were not previously allowed.
15 comments - Posted Oct 12, 2009
MSGI Security Solutions, which "serves the needs of counter-terrorism, public safety, law enforcement, and commercial security," has moved into a new area: diabetes detection. In fact, it has developed a handheld sensor that detects diabetes by measuring the level of acetone in the breath. The device, which employs carbon-based chemical sensors that detect organic vapors, is based upon nano sensors that NASA originally developed to make scientific measurements during space missions.
7 comments - Posted Oct 9, 2009
So close, and yet so far. It looks like there will be no marketing partnership for MannKind's ultra rapid-acting insulin product Afresa anytime soon. The company had planned to enter into a deal with a large pharmaceutical company by the end of this year, but now approval from the Food and Drug Administration (FDA) for their inhaled insulin won't be until January 2010, at the earliest.
3 comments - Posted Oct 8, 2009
A study coming out in the November issue of the Clinical Journal of the American Society of Nephrology is reporting that type 2 men whose blood contained a high count of eosinophils, a sign of allergic inflammation, also had albumin in their urine, which is an early indication of kidney disease. Eosinophils are white blood cells that increase in number during an allergic reaction. Albumin is a protein in the blood that helps regulate blood volume and acts as a carrier for other molecules. Albumin is not normally found in the urine, however, because when healthy kidneys filter the blood, they retain what the body needs (like proteins) and allow only smaller "impurities" into the urine. But during diabetes, too much blood sugar can damage the filtering structures of the kidneys, causing them to thicken and become scarred. Eventually, they begin to leak, and protein (albumin) begins to pass into the urine.
0 comments - Posted Oct 6, 2009
Nature is wonderfully complex. During the second trimester of pregnancy, when the fetus is growing rapidly, hormones from the placenta begin to reduce the ability of the mother's insulin to bind with insulin receptors. Because the mother's insulin is consequently less able to shuttle glucose out of her bloodstream, the growing fetus is guaranteed a good supply of blood glucose.
0 comments - Posted Oct 6, 2009
The enthusiasm for inhaled insulin has waned, to say the least, since Exubera was pulled off the market by Pfizer. Following the Exubera debacle, the development of two other inhaled insulins (AIR by Eli Lilly and Alkermes, and AERx by Novo Nordisk) was halted as well.
14 comments - Posted Oct 5, 2009
Researchers at Children's Hospital in Boston think that they may have created the most reliable means yet of delivering drugs that cannot be taken orally. Their solution is to combine nanotechnology and magnetism to create a delivery system that is simple, but extremely durable and accurate.
2 comments - Posted Oct 3, 2009
Having diabetes involves a lot of pretty complex arithmetic. You've got to calculate carbs from nutrition labels, total the calories and carbohydrates in a meal, calculate insulin dosage based on insulin-to-carbohydrate intake, and on and on. These tasks aren't simple: They require an understanding of measurement, estimation, time, logic, and multi-step operations, and the knowledge of which math skills to apply to each problem.
3 comments - Posted Oct 2, 2009
"Ask any of the elite who have become truly massive beasts which anabolic substance has had the most profound effect upon their physique, and the answer from the largest mammals will unanimously be insulin." That's a quote from Iron Magazine, a publication for body builders. Apparently, injecting insulin for its anabolic properties is not uncommon among the "massive beasts," as several body-building websites actually contain instructions on how to do it and what types of insulin to use.
0 comments - Posted Oct 1, 2009
In August, I had the pleasure of traveling to Atlanta, Georgia to attend the American Association of Diabetes Educators (AADE) annual meeting. I sat in on several seminars, the most interesting of which are summarized here.
0 comments - Posted Oct 1, 2009
In our June/July 2009 issue, we published a letter from reader Sheila Payne, who wrote that we had been far too positive about continuous glucose monitoring (CGM) in our June/July article Get the Facts on Continuous Glucose Monitoring. Her letter provoked a stack of letters from people who believe that the benefits of CGM substantially outweigh its negatives. To let you in on the debate, we are reprinting Ms. Payne's thought-provoking letter here, followed by two equally thoughtful responses from readers.
0 comments - Posted Oct 1, 2009
September 2009
Clinical trials are conducted before a new drug is released for sale, in part to test for bad things that might happen when people take it. But clinical trials don't involve all that many people: several thousand at the most. After the clinical trials are successfully completed, however, the drug is sold to millions upon millions. Merck's sales of Januvia and Janumet, for example, totaled over a billion dollars in the first six months of this year alone.
1 comment - Posted Sep 30, 2009
One thing that really frustrates people with diabetes mellitus is the biopharma industry's focus on treatments rather than cures. A cure is what the diabetes community wants, not another band-aid. So the existence of a biopharma company that calls itself "CureDM" is promising, and its first product, Pancreate, seems to be on its way to fulfilling that promise.
21 comments - Posted Sep 28, 2009
The way information is presented to us makes a big difference in whether we are able to integrate that information into our daily lives. Although graphs and numbers may sway some people, putting educational materials into a culturally relevant context can be more effective. A recent study, for example, has found that a dietary program based on the Medicine Wheel Model for Nutrition can change eating patterns among Native Americans, who have the highest rates of obesity, diabetes, and cardiovascular disease of all ethnic groups.
2 comments - Posted Sep 26, 2009
Metformin has always been the old reliable for treating new onset type 2 diabetes, but it's beginning to look like it's got a new calling as a cancer treatment. Diabetes Health recently reported on the fact that metformin reduces a type 2 person's risk of pancreatic cancer by up to 62 percent. It's also been observed that people with type 2 who take metformin have a much lower cancer incidence than those who don't. Now it appears that metformin can help with breast cancer treatment as well. A study of mice with breast cancer generated from human breast cancer cells has found that they remained tumor-free for nearly three months on metformin combined with doxorubicin, a standard cancer chemotherapy. In mice given only the doxorubicin, the tumors recurred.
1 comment - Posted Sep 25, 2009
Scientists have noted for a long time that the hormone leptin suppresses appetite. That's why they have been puzzled by the high levels of leptin found in obese people-shouldn't leptin decrease their appetites and act as a curb on their weight? Leptin also suppresses bone mass accrual, yet obese people do not suffer from loss or weakening of bone mass, despite their high leptin levels.
0 comments - Posted Sep 25, 2009
Even if they don't lose weight, a moderate aerobic exercise program can improve insulin sensitivity in obese adolescents who are sedentary.
4 comments - Posted Sep 23, 2009
That old dog is me (thirty-seven years living with diabetes). There's a lot to be said for teaching someone who's lived with diabetes for years new ways to manage diabetes, and some new things that have come into the marketplace recently.
9 comments - Posted Sep 20, 2009
By reprogramming skin cells from people with type 1 diabetes, scientists have produced beta cells that secrete insulin in response to changes in glucose levels. Dr. Douglas Melton and his colleagues at the Harvard Stem Cell Institute started by using the skin cells to generate induced pluripotent stem (iPS) cells. Once they had iPS cells, the researchers manipulated them into developing into pancreatic islet (beta) cells.
4 comments - Posted Sep 19, 2009
SANTA BARBARA, Calif. (August 26, 2009) - The nation's nonprofit community health centers and free clinics saw a 13 percent increase in uninsured patients with diabetes seeking care during the first six months of 2009 versus the same period in 2008, according to the results of a national survey released today by humanitarian medical aid organization Direct Relief International.
3 comments - Posted Sep 17, 2009
Those of you who are familiar with the South know what kudzu is. An Asian vine that can grow a foot taller every day, it was brought to the American Southeast in the 1930s in a sadly boneheaded attempt to control erosion. Unfortunately, the little green visitor liked it here so much that in the decades since, it has colonized 10 million acres of farms and woods, becoming a massive and costly nuisance.
0 comments - Posted Sep 16, 2009
ALEXANDRIA, VA, Sep 01, 2009 (MARKETWIRE via COMTEX) - The American Diabetes Association Research Foundation has selected two scientists, University of Virginia Health System researcher Zhenqi Liu, MD, and Stanford University School of Medicine researcher Gerald Reaven, MD, to receive the American Diabetes Association-Novo Nordisk Clinical/Translational Research Award.
0 comments - Posted Sep 12, 2009
Visceral adipose tissue (VAT), familiarly known as visceral fat, has long been associated with metabolic risk. But VAT is closely correlated with liver fat, also called intrahepatic triglyceride (IHTG) content. As a result, Samuel Klein of the Washington University School of Medicine in St. Louis, Missouri, set out to determine if liver fat is more closely correlated with complications in obese patients than VAT.
0 comments - Posted Sep 12, 2009
Adults newly diagnosed with type 2 diabetes generally don't take to the idea of using insulin right off the bat. They're worried about gaining weight and fear low blood sugars. They're also concerned about whether they can manage the regimen and fear that taking insulin will lower their quality of life. Those concerns, however, might be assuaged by a study recently conducted by Ildiko Lingvay and his colleagues at the University of Texas Southwestern.
5 comments - Posted Sep 12, 2009
I remember it like it was yesterday. It was the night before Thanksgiving, and my family and I were driving to my parents' house for the holiday weekend. I am usually the one who drives, but this time my wife insisted on taking the wheel because I was so dizzy and light-headed that I could hardly stand upright. Over the course of the previous week, I had not been feeling well. I had been getting up frequently at night to use the bathroom, was insatiably thirsty, and had been so dizzy that I had actually fallen down several times.
7 comments - Posted Sep 11, 2009
Juice extracted from North American lowbush blueberries, biotransformed with bacteria from the skin of the fruit, holds great promise as an anti-obesity and anti-diabetic agent. The study, published in the International Journal of Obesity, was conducted by researchers from the Université de Montréal, the Institut Armand-Frappier and the Université de Moncton who tested the effects of biotransformed juices compared to regular blueberry drinks on mice.
3 comments - Posted Sep 10, 2009
It's not on the market yet, but a patch composed of tiny needles, each the width of a few human hairs, could eventually replace hypodermic needles for most drug injections. Preliminary experiments with people with diabetes have shown that the patch can deliver insulin successfully and with less pain than a hypodermic.
5 comments - Posted Sep 9, 2009
A South Carolina study has found that the DASH diet, originally designed to treat hypertension, is linked to a lower rate of type 2 diabetes in whites, but not in blacks or Hispanics.
0 comments - Posted Sep 4, 2009
The famous Diabetes Control and Complications Trial, known to its friends as the DCCT, was the first to prove the power of "intensive control" of blood glucose to reduce the complications of diabetes. Although the ten-year study ended in 1993, researchers have continued to follow about 90 percent of the nearly 1,500 original DCCT volunteers. And the follow-up study, called the Epidemiology of Diabetes Interventions and Complications (EDIC), is measuring up to its illustrious parent in terms of demonstrating the value of tight control. According to results published in the July 27, 2009 issue of the Archives of Internal Medicine, microvascular and cardiovascular complications of type 1 diabetes are cut in half for patients with near-normal glucose.
11 comments - Posted Sep 4, 2009
Researchers at Stanford University recently discovered that a mutated version of a gene may contribute to type 1 diabetes by sabotaging the functioning of the gene's normal version. Experiments conducted on mice with a diabetes-type disease showed that the mutated variant may prevent the healthy version from protecting the insulin-producing cells in the pancreas from attack by the immune system.
0 comments - Posted Sep 3, 2009
August 2009
A Japanese company whose biggest moneymaker is the sale of synthetic fabrics announced a few days ago that it has developed an insulin nasal spray for people with diabetes. The news brought an investor surge that lifted the value of its stocks by 10 percent.
0 comments - Posted Aug 28, 2009
Our genes are like a recipe for a human. It's a very complicated recipe, determining how much of this protein and how much of that enzyme need to be added into the mix in order for us to function properly, but our genes are pretty good at getting it right. Although we are still learning how the recipe works, what ingredients (gene products) are involved, and when are they are produced, our knowledge is growing fast.
2 comments - Posted Aug 28, 2009
In our last issue, we published a letter from reader Sheila Payne, who wrote that we had been far too positive about continuous glucose monitoring (CGM) in our June/July article Get the Facts on Continuous Glucose Monitoring. But her opinion provoked a stack of letters from people who believe that the benefits of CGM substantially outweigh its negatives. To let you in on the debate, we are reprinting Ms. Payne's thought-provoking letter here, followed by two equally thoughtful responses from readers.
12 comments - Posted Aug 28, 2009
Canadian scientists have reported that a hormone found in the gut has the power to lower glucose production by signaling the brain and liver to do so. When the researchers activated its receptors in lab rats, they found that the hormone, called cholecystokinin (CCK) peptide, rapidly lowered the animals' blood glucose levels.
0 comments - Posted Aug 27, 2009
A new glucagon-like peptide-1 (GLP-1) analog for type 2s that might require dosing only once a month is now in pre-clinical (animal) studies. GLP-1, which increases insulin secretion from the pancreas, is a mighty helpful molecule, but with a sadly brief lifespan. It's broken down in the body within minutes by the enzyme DPP-4. That's why drugs like Merck's Januvia, a DPP-4 inhibitor, is effective: blocking DPP-4 subsequently increases the amount of GLP-1 in the system.
0 comments - Posted Aug 25, 2009
The U.S. Food and Drug Administration has issued a warning against the use of GDH-PQQ blood glucose test strips by people with diabetes who are taking medications that contain non-glucose sugars. [Note: GDH-PQQ is the abbreviation of "glucose dehydrogenase pyrroloquinoline quinone," a chemical that reacts with the non-glucose sugars maltose, galactose, and xylose, which are contained in some therapeutic products.]
10 comments - Posted Aug 24, 2009
It's called an anti-Ras drug, but it's got no problem with reggae. It's a multi-talented new pill against pancreatic cancer that just might also come to the rescue of pancreatic beta cells. Its pancreatic cancer-fighting attributes are currently being tested in a human clinical trial, but a modified version has been shown to maintain normal insulin production in diabetic mice.
1 comment - Posted Aug 21, 2009
In June, I attended the ADA's 69th Scientific Sessions Conference that was held in New Orleans this year. Among other presentations, I listened to Mary Sullivan's very interesting talk offering practical advice on better inpatient diabetes care. We've written numerous times online about how hospital glycemic control needs to be improved. For example, you can read our article on DiabetesHealth.com called, "U.S. Academic Medical Centers Are Not Cutting the Mustard."
0 comments - Posted Aug 20, 2009
One of the major complications of diabetes is diabetic nephropathy, a loss of kidney function that may lead to renal failure. As kidney disease progresses, the barrier that keeps large molecules out of the urine, called the glomerular barrier, begins to break down. With the barrier failing, certain large molecules begin to migrate into the urine. One of those hefty molecules is immunoglobulin M, or IgM.
1 comment - Posted Aug 19, 2009
The American Diabetes Association estimates that about 18 million Americans have diabetes. Given that millions of people have lost their jobs during the current recession, the law of averages would suggest that at least a few hundred thousand folks with diabetes are now unemployed. Loss of a job, unfortunately, usually means a concurrent loss of health insurance. For those hundreds of thousands of people with diabetes, no health insurance means big trouble.
0 comments - Posted Aug 18, 2009
The theory of unintended consequences has gotten another boost. Although two drugs designed to slow the loss of kidney function in people with type 1 diabetes turned out to be busts, they had a wonderful but entirely unexpected side effect: Eye damage was reduced by 65 to 70 percent in the patients taking them.
6 comments - Posted Aug 17, 2009
Only a handful of studies have examined the relationship of a woman's menstrual cycle to her blood glucose control, but they have one finding in common: menstruation's effect on blood glucose is as varied as each individual's disease. As a result, blood glucose testing remains the only way to know how a woman's monthly cycle affects her diabetes control.
9 comments - Posted Aug 15, 2009
Onglyza (saxagliptin), a dipeptidyl peptidase-4 (DPP-4) inhibitor produced by AstraZeneca and Bristol-Myers Squibb, has been approved by the US Food and Drug Administration (FDA) for the treatment of type 2 diabetes.
2 comments - Posted Aug 15, 2009
If it's a pump, then where's the tubing? Well, it looks like another company has put a patch on that problem. Medingo Ltd., a company held by Elron Electronic Industries, has received FDA approval to market the Solo MicroPump Insulin Delivery System. The Solo System consists of an insulin-dispensing patch and a remote control device that increases or decreases the patch's rate of secretion.
6 comments - Posted Aug 15, 2009
This year the American Association of Diabetes Educators (AADE) went deep south for its annual conference, hosting the event in Atlanta, Georgia, from August 3rd through August 9th. Diabetes Health was there, hobnobbing with thousands of attendees and hundreds of companies, and it was an amazing experience.
0 comments - Posted Aug 15, 2009
Endocrinologists at the University of Chicago say that lack of sufficient sleep may contribute to insulin resistance and decreased glucose tolerance, two conditions that up the long-term risk of developing type 2 diabetes.
0 comments - Posted Aug 14, 2009
There's a gene whose name you should remember because it could mark a crucial point in the war on type 1 diabetes.
3 comments - Posted Aug 13, 2009
Now there's an iPhone and iPod Touch app for diabetes. AgaMatrix, Inc., the makers of the WaveSense line of blood glucose monitoring products, has announced the launch of the WaveSense Diabetes Manager, an electronic diabetes logbook software application that runs on the two Apple products.
The WaveSense Diabetes Manager, in development and testing for over a year, lays the foundation for a series of upcoming products that will take advantage of the iPhone and other mobile platforms to help people with diabetes manage the disease. AgaMatrix reports that the WaveSense app provides users with the following features:
2 comments - Posted Aug 12, 2009
Until the twentieth century, type 1 diabetes was a fatal disease. Once we came to understand how insulin works in the body, however, everything changed. The discovery of the role of insulin was a group effort by people who didn't know each other, but built on each others' work. In 1869, a German medical student named Paul Langerhans figured out the regulatory role of insulin in the mammal body. In honor of his efforts, his name was given to the islets of Langerhans, where insulin is synthesized within the beta cells of the pancreas. Other Europeans and North Americans made important advancements right up until January 23, 1922, when a 14-year-old boy who was dying of diabetes at Toronto General Hospital was given the first successful injection of cow insulin.
2 comments - Posted Aug 10, 2009
Last May, 24-year-old Charlie Kimball was in Car #35, taking Turn 3 at the Indianapolis Motor Speedway during the Firestone Freedom 100. He was in radio contact with his pit crew, who informed him that he had a headwind coming out of the turn and onto the 5/8 mile "straight." Charlie kept an eye on the car next to him, moving closer and beginning to crowd it on the inside. Having raced professionally for six years, he knew that he had to make a move, and soon. He shifted into sixth gear and accelerated.
2 comments - Posted Aug 8, 2009
A study from Massachusetts General Hospital and Harvard Medical School in Boston says that magnetic resonance imaging could become a useful tool for diagnosing diabetes and helping doctors determine the proper course of treatment.
3 comments - Posted Aug 8, 2009
Initially diagnosed with type 2 diabetes, Rob subsequently discovered that he had type 1. Knowing that he needed to exercise more, he returned to professional surfing. Today, he is a sponsored professional athlete who uses a CGM.
10 comments - Posted Aug 7, 2009
Most clinical studies of new drugs are conducted primarily on white men, whether or not they are most affected by the disease the drug is intended to treat. African Americans, for example, are 1.6 times more likely to have diabetes than non-Hispanic whites. Why should we assume that what works for white males will also be effective for African Americans, Hispanics, Asians, or, for that matter, women?
0 comments - Posted Aug 6, 2009
Metformin is one of the oldest and most tried-and-true diabetes treatments around, but apparently it has a new talent. According to research from the M.D. Anderson Cancer Center at the University of Texas, good ol' metformin reduces a type 2 person's risk of pancreatic cancer by 62 percent.
2 comments - Posted Aug 5, 2009
In April of 2008, our healthy nine-year-old son, Gaspar, was diagnosed with type 1 diabetes. After his two days in the ICU and a week in the hospital, a new life began for all of us. Although we couldn't immediately grasp all its implications and were simultaneously dealing with our shaken world, we gave the situation a "think outside the box" approach. When the endocrinologist told us, "That's the way it is. Just focus on the controls and all will be fine," we asked whether the condition might be cured or attenuated if we acted quickly at the beginning. We were met with the usual answer: "There's nothing you can do. Just focus on the controls."
8 comments - Posted Aug 3, 2009
It's very likely that you, like most people, believe many myths about diabetes. If you do, you might actually be doing yourself harm. Learning the truth can empower you (as it did me) to make choices and take actions that increase the quality and length of your life.
9 comments - Posted Aug 1, 2009
In 1994, Kelli Kuehne was on a roll. That year, she won the United States Girls Junior Amateur Golf Championship and a year later, she won the U.S. Women's Amateur Golf Championship, repeating that win in 1996 while also taking the British Ladies Amateur Golf Championship. The roll continues. Today, Kelli Kuehne is still playing matches in the LPGA and, through it all, has never allowed type 1 diabetes to beat her on the golf course or in her life.
0 comments - Posted Aug 1, 2009
Because we have good health insurance, my son sees his endocrinologist twice a year, his diabetes health educator twice a year, and his nutritionist once a year. Meanwhile, he sees his school nurse one to three times a day. As you know, this relationship can make a difference for the rest of a child's life.
0 comments - Posted Aug 1, 2009
Xenotransplantation ("zee-no-transplantation") may sound like something from a space invasion novel, but it's actually the practice of transplanting organs, cells, or tissues from one animal species into another. With scientific advances taking place so rapidly and with so many patients desperate for organ transplants, it seems plausible (and pretty likely) that one day xenotransplantation will be commonplace.
1 comment - Posted Aug 1, 2009
July 2009
May 5 - Ann Arbor, MI - In the first study of the effects of statins on the concentrations of both low-density lipoprotein cholesterol (LDL-C; known as the "bad" cholesterol) and low-density lipoprotein particles (LDL-P) in patients with metabolic syndrome, it was shown that even though the statins lowered the concentrations of LDL-C to target levels, the patients retained considerable residual risk for cardiovascular events because LDL-P concentrations were not reduced to a similar extent. A pre-print version of the study in Diabetes Care is available online at http://dx.doi.org/10.2337/dc08-1681, and the final version will be available in print in the June 2009 issue, as well as online at the same URL.
0 comments - Posted Jul 29, 2009
A protein that builds up in the pancreases of baboons and leads to the suppression of insulin-producing beta cells, may provide one of the most significant indicators yet for predicting the onset of type 2 diabetes.
1 comment - Posted Jul 28, 2009
Banting Gives It Away - Insulin was discovered in 1921 by Fred Banting and Charles Best. In a generous gesture that unfortunately didn't start a trend, they sold the patent for a dollar so that cheap insulin would quickly become available. It worked like a charm: within two years, Eli Lilly had sold 60 million units of its purified extract of pig and cow pancreas.
22 comments - Posted Jul 27, 2009
High percentages of endocrinologists, primary care physicians, and managed care organizations surveyed by a research firm say they would like to see additional GLP-1 analogues like Amylin/Eli Lilly's Byetta® and DPP-IV inhibitors like Merck's Januvia® available to treat type 2 diabetes.
6 comments - Posted Jul 25, 2009
After experiencing blurry vision and excessive thirst, Mr. R visits his primary care doctor, who tests him and diagnoses diabetes and high lipid levels. Mr. R is placed on hypoglycemic and statin medications and sent to a dietitian for nutritional advice, but he is confused about to how to shop and cook according to the new recommendations. In the next weeks, he experiences dangerous blood glucose swings and inadequate improvement in his LDL level. His primary care doctor refers him to an endocrinologist, but the next available appointment is three months away. What now?
6 comments - Posted Jul 24, 2009
According to results of a phase II clinical trial at the University of Texas Medical School, a low dose of oral interferon alpha can preserve pancreatic beta cell function in newly diagnosed type 1 diabetes patients. Interferons are proteins produced by the cells of the immune system in response to challenges like a virus or a tumor cell. They work by inhibiting viral replication in the host cell, activating natural killer cells, and increasing the activity of other immune system cells such as lymphocytes.
0 comments - Posted Jul 24, 2009
Never underestimate the power of people with diabetes and their families. When we as a consumer group purchase more fruits and vegetables, walk or bicycle instead of taking the car, and educate ourselves about a healthy lifestyle, we are addressing global issues as well as personal ones and can have a strong, positive effect on the future.
1 comment - Posted Jul 23, 2009
For obese people, who often go on to develop type 2 diabetes, the magic bullet would be a drug that causes weight loss without surgery or the misery of drastic diets that often fail. So, news about a drug that produced dramatically slimmer lab rats in just a week should make them-and people with diabetes-perk up.
0 comments - Posted Jul 23, 2009
A man who has been married for 15 years suddenly begins losing weight and buying new clothes. He starts staying late at work and taking weekend business trips, unusual behaviors for him. His wife thinks he is having an affair. Why?
0 comments - Posted Jul 22, 2009
Minneapolis-based Medtronic Inc. is recalling some lots of its Quick-set infusion sets over concerns that they may cause insulin pumps to deliver too much or too little insulin.
1 comment - Posted Jul 21, 2009
Growth hormones, peer pressure, independence struggles, and mood swings: welcome to the teenage years! There's nothing like a warning glance from a fed-up teenager to make a parent retreat. As your child takes more control of his or her diabetes, it becomes ever more tempting to step back and avoid the friction that sometimes comes from being involved. Nevertheless, your teenager needs your reliable presence more than ever. The beauty, strength, and sheer courage our kids exhibit in meeting their teenage challenges can inspire us to stand up and work with them to keep their health and well-being firmly in the forefront of their minds. Each child and each situation is different, but here are a few suggestions for staying on your teen's diabetes team.
0 comments - Posted Jul 17, 2009
Rhode Island researchers say they have found strong evidence that links the level of nitrates in the environment and food supply to increases in deaths from such diseases as diabetes, Alzheimer's, and Parkinson's-all insulin-resistant ailments.
1 comment - Posted Jul 16, 2009
Medicare offers: Screenings for people at risk, Diabetes self-management training, Medical nutrition therapy services, Hemoglobin A1c tests, Glucose monitors, test strips, lancets, insulin, and some insulin pumps, Glaucoma tests, Foot exams, foot treatment, and therapeutic shoes, Flu and pneumonia shots, and Cholesterol and lipid checks.
1 comment - Posted Jul 15, 2009
Obesity has always been one of the major precursors to type 2 diabetes because of its ill effects on the body's ability to properly use insulin. But until now, scientists haven't been able to say with certainty just what happens in obese people to increase their insulin resistance.
0 comments - Posted Jul 14, 2009
People often ask me, "Why limit diabetes-related services to the iPhone when there are so many other cell phones out there?" I always answer them by asking, "How many applications have you downloaded onto your cell phone?"
15 comments - Posted Jul 13, 2009
April 2009 was an exciting month at the University of Alberta. It marked the tenth anniversary of an unprecedented approach to islet transplantation, recognized globally as the "Edmonton Protocol." Each year since that milestone has produced evidence of progress in the art of islet isolation and the science of the transplant process. I know this because I lived it. I am patient number thirty-three, one of the many who have witnessed the evolution of this continuing innovation.
7 comments - Posted Jul 11, 2009
Dear Aisha and David: I am a 66-year-old woman who has had diabetes for over 64 years. My husband is 52. He wants sex two or more times day. I hate it. I have no sexual drive, and most of the time it is painful. It was not always like this, but he has always wanted more sex than any man I know! We talk about things, but he basically ignores a lot of what I say when it comes to sex. He is actually a very caring person and has put up with a lot considering all the complications I have after 64 years of diabetes. We have been together for 18 years (married for nine). He waits on me hand and foot. I have to tell him to let me do things myself!
14 comments - Posted Jul 10, 2009
Of all the quests that researchers have undertaken in search of a cure or decisive treatment for type 1 diabetes, the search for a vaccine has to be the boldest. But how would you develop such a vaccine, and how would it work?
2 comments - Posted Jul 9, 2009
I would exercise if I had more time... if I had a health club membership... if it didn't hurt so much... if I knew what exercises to do... if I could do it with my family... if I could control my blood sugar...
0 comments - Posted Jul 8, 2009
Roche Diabetes Care Announces Unique Coaching Program for Diabetes Educators as Part of Long-Term Commitment to Fight the Disease
1 comment - Posted Jul 8, 2009
The International Diabetes Federation (IDF) has called for urgent assessment and responses from regulatory authorities into a possible link between the use of insulin glargine (an insulin analog) and increased risk of cancer. The proposed link is based on findings published on June 26, 2009, in Diabetelogia, the journal of the European Association for the Study of Diabetes (EASD).
2 comments - Posted Jul 6, 2009
UK-based GW Pharmaceuticals has entered into a strategic alliance with Professor Mike Cawthorne and the Clore Laboratory, University of Buckingham, to research the use of cannabinoids-chemical compounds derived from marijuana-in the treatment of type 2 diabetes.
3 comments - Posted Jul 5, 2009
Scientists have identified five genetic biomarkers that predict how well a type 2 patient will respond to the drug Actos. Their work could be the first step toward a system that would allow doctors to predetermine which drugs will best help each person with diabetes.
0 comments - Posted Jul 3, 2009
By inhibiting the expression of a gene called sirtuin 1, Yale researchers have been able to reduce blood glucose levels, decrease the liver's production of glucose, and increase insulin sensitivity in rats conditioned to exhibit type 2 symptoms. A happy byproduct of their research is a simultaneous lowering of cholesterol levels.
0 comments - Posted Jul 3, 2009
How many times during your work with young people and their families have you wished that you could really help them through a rough time in their lives? Young people with diabetes and their families often feel overwhelmed, both physically and emotionally, by all that they must learn and manage. They can feel very alone if they don't know anyone who can understand their diabetes fears and trials.
0 comments - Posted Jul 2, 2009
Patriotism, parades, parties, and pyrotechnics - July Fourth is a high intensity day of celebrations and national pride. In many towns, families move from one exciting event to the next, and the day can be very unpredictable. Still, parents of children with diabetes want carefree time with their families, and children don't want to think about diabetes details. A bit of advanced planning and packing can make this festive day much easier.
0 comments - Posted Jul 2, 2009
Genentech, a bioscience firm famous for its development of antibodies designed to combat cancer, has entered a $350 million agreement with Bayhill Therapeutics to assist in development of BHT-3021, a drug that treats type 1 diabetes by reducing or stopping immune system attacks on pancreatic beta cells.
2 comments - Posted Jul 1, 2009
June 2009
Every time I return from the American Diabetes Association (ADA) Scientific Sessions conference, my head is so full of information that I need a week or two to sort through it. But now I've had a chance to choose what I think are the top five things that you need to know. Here they are...
0 comments - Posted Jun 30, 2009
Until now, care for insulin-dependent diabetes has focused on the delivery of insulin combined with frequent blood glucose (BG) testing. Keeping your A1c down is, and always will be, the name of the game. But numerous studies have shown us in the last few years that having access to continuous glucose data has a huge impact. How you deliver the insulin doesn't necessarily matter-you can use a pump, a syringe, or an insulin pen, it's knowing your personal BG trends that makes all the difference.
11 comments - Posted Jun 29, 2009
Rachel and her husband adopted a beautiful baby girl in November of 2008. Their daughter is now seven months old. You can read Rachel's article about diabetes and adoption here.
5 comments - Posted Jun 26, 2009
In May, 2009, a jury in the United States District Court for the District of Columbia found that the Federal Bureau of Investigation (FBI) discriminated against Jeff Kapche when it refused to hire him as a Special Agent because of his diabetes.
0 comments - Posted Jun 26, 2009
The American Heart Association (AHA) has added weight training to the list of exercises it recommends for people with type 2 diabetes to reduce their risk of cardiovascular disease. Heart and blood vessel diseases account for nearly 70 percent of deaths among type 2s.
0 comments - Posted Jun 25, 2009
One of the fondest hopes of people with type 1 diabetes has long been for the creation of an artificial pancreas, a reliable combination of automated glucose monitoring and insulin delivery that could serve in place of a defunct pancreas.
16 comments - Posted Jun 24, 2009
With Type 2 diabetes emerging as an epidemic, primary care clinicians need to become savvy at initiating and adjusting insulin. Given the nationwide shortage of endocrinologists, referring all patients on insulin for endocrine appointments is not realistic in most areas of the country.
0 comments - Posted Jun 24, 2009
The U.S. Food and Drug Administration has learned that some stolen vials of the long-acting insulin Levemir made by Novo Nordisk Inc. have reappeared and are being sold in the U.S. market. Three lots or a total of 129,000 vials of this product were stolen in all. These stolen insulin vials may not have been stored and handled properly and may be dangerous for patients to use.
1 comment - Posted Jun 22, 2009
In 2008, the U.S. Food and Drug Administration published strong warnings that the type 2 diabetes drug exenatide (trade name Byetta) might increase risk of acute pancreatitis, a painful inflammation of the pancreas. The FDA's action came in the wake of reports that 30 exenatide users had come down with pancreatitis and that six of them had died from the condition.
1 comment - Posted Jun 19, 2009
I hear voices in my surroundings as the cloud of confusion gradually begins to lift. "Curtis, can you hear me?" "Curtis, what was the score of the football game?" "Curtis, do you know where you are?"
6 comments - Posted Jun 18, 2009
Gale Fullerton is a 65-year-old Californian who has the distinction of being a Joslin 50-Year medal winner. Elliott P. Joslin, M.D., knew that good self-management was the key to minimizing long-term diabetes complications, and the medal program was designed as an incentive for those committed to good diabetes care. In 1970, Joslin Diabetes Center expanded the program and began awarding a 50-year bronze medal. They presented the first 75-year medal in 1996.
24 comments - Posted Jun 16, 2009
Drug companies spend billions of dollars on research, and it's obvious that they spend more billions on advertising. Well, according to the New York Times, they spend the most billions on giving nice things to doctors: pens, samples, banquets, trips, and educational opportunities among them. For doctors, in fact, there is a free lunch: Pharma companies spend as much as a billion a year just on lunches for doctors. And over 90 percent of doctors have accepted at least some of this largesse from the industry.
5 comments - Posted Jun 12, 2009
Patients with type 2 diabetes reduced their risk of having a foot amputated by 36 percent when they took fenofibrate, a drug designed to lower blood fat levels.
0 comments - Posted Jun 12, 2009
A previously unknown human protein, called CHC22, may give scientists a powerful new tool for understanding type 2 diabetes, according to researchers from the University of California, San Francisco, and Harvard Medical School.
0 comments - Posted Jun 11, 2009
CRx-401, an insulin sensitizer intended to assist metformin in type 2 diabetes therapy, has successfully completed a Phase 2 clinical trial in which patients taking it saw their fasting plasma glucose drop by 12 mg/dl after 90 days.
1 comment - Posted Jun 3, 2009
Novo Nordisk has announced that results from a study show that almost 60 percent of type 2 patients taking once-daily doses of its Levemir insulin analog were able to reach the average blood sugar level recommended by the American Diabetes Association.
3 comments - Posted Jun 2, 2009
Diabetes most commonly occurs in middle age to older dogs and cats, but occasionally occurs in young animals. When diabetes occurs in young animals, it is often genetic and may occur in related animals. Diabetes occurs more commonly in female dogs and in male cats, according to the Washington State University College of Veterinary Medicine.
0 comments - Posted Jun 1, 2009
The polls are open for voting for new members of the AADE board, AADE officers, and the nominating committee. The good news is that you can vote for three people! Diabetes Health wishes Board of Directors candidates and former DH Guest Editors, Jane Jeffrie Seley, Kim Higgins, and Deborah Greenwood, the best of luck.
0 comments - Posted Jun 1, 2009
Never underestimate the power of people with diabetes and their families. When we as a consumer group purchase more fruits and vegetables, walk or bicycle instead of taking the car, and educate ourselves about a healthy lifestyle, we are addressing global issues as well as personal ones and can have a strong, positive effect on the future.
0 comments - Posted Jun 1, 2009
May 2009
In a recent 16-week randomized, open-label pilot study, 169 patients were randomized to receive Welchol (n=57), Januvia (n=56), or Avandia (n=56).1 The results demonstrated that Welchol (colesevelam HCl) significantly improved glycemic control and reduced mean LDL cholesterol (LDL-C) when added to metformin monotherapy in patients with type 2 diabetes. In the study, Januvia® (sitagliptin) and Avandia® (rosiglitazone) also significantly improved glycemic control, but LDL-C increased in patients on both of these treatment regimens.
0 comments - Posted May 29, 2009
United Way recently presented the 2009 United Way Spirit of America award, its highest national award, to Eli Lilly and Company. "In these challenging times, it's more important than ever to have generous partners like Lilly who are committed to strengthening our nation's communities," said Brian Gallagher, president and CEO of United Way. "Whether it's serving as a ReadUP tutor or donating life-saving medicines, Lilly and its employees understand that improving lives in this environment requires resources coupled with active and dedicated volunteers. United Way is proud to honor them with our highest national award."
0 comments - Posted May 28, 2009
A study of Merck's Januvia (sitagliptin), a drug for patients with type 2 diabetes, has found that its use can lead in some patients to a low-grade form of pancreatitis and an increased risk of pancreatic cancer in the long term. However, the study, conducted at the Larry L. Hillblom Islet Research Center at UCLA, also found that the risks associated with Januvia as a monotherapy are removed when the drug is used in conjunction with metformin (trade name Glucophage). Metformin, a low-cost drug that controls glucose production by the liver, is one of the oldest and most benign standbys in the anti-diabetes arsenal.
0 comments - Posted May 27, 2009
Wow. It's like discovering that the orchestra's second violinist, who does a good job but just isn't as glamorous as the first violinist, also has a fantastic operatic singing voice. In this case, the surprise comes from metformin, the solid performer that since the 1950s has been the first non-insulin drug that doctors prescribe to newly diagnosed type 2s.
4 comments - Posted May 27, 2009
Pump Wear has a new product called a "Draw Pak"-it's a pump pack that you can truly make your own. The pack, which is made of black cordura, has a white vinyl front that your can decorate yourself with "Sharpie" permanent markers. (Hint: Costco sells a package of every color you could possibly need.) Want to practice your picture? Use washable markers to play with your ideas, then wipe it clean until you're ready for the final design. Test your creativity and create your own sports design, fun fashion design, or special events logo-it's all up to you.
1 comment - Posted May 26, 2009
If you have type 2 diabetes, you know that regular sustained exercise is one of the best and easiest ways to manage the disease. At the same time, proper nutrition-eating low glycemic foods, avoiding carbohydrates, and taking supplements, such as vitamins and omega-3 fatty acids-is the other key to non-medicinal control of blood sugar levels.
6 comments - Posted May 26, 2009
Doctors who treat diabetes must often feel like moms who spend 18 years reminding their kids to pick their socks up off the floor. "It just takes two seconds, and your reward is a clean room and a less grumpy mother."
1 comment - Posted May 22, 2009
Smoking has severe effects on your diabetes and your health. Quitting smoking will give you more energy, better control of your diabetes, and less chance of a heart attack or stroke.
5 comments - Posted May 21, 2009
My husband, Simon, was diagnosed with type 2 diabetes in October 2004. It was managed via oral medication at first, but his blood sugar levels were hard to control, and his doctor prescribed insulin to stabilize his condition.
0 comments - Posted May 21, 2009
Humanin (HN) is a mitochondrial peptide* that in some research has shown the ability to protect against the death of neurons, the devastating consequence of diseases like Alzheimer's. According to the leader of a research team at the Albert Einstein College of Medicine at Yeshiva University in the Bronx, however, it also significantly improves the insulin sensitivity of diabetic rats and sharply drops their glucose levels.
2 comments - Posted May 20, 2009
Significant relief for people with type 1 diabetes could soon come in the form of a device made from a thermoplastic resin commonly used as a coating for cookware, gaskets, and hoses.
2 comments - Posted May 20, 2009
The polls are open for voting for new members of the AADE board, AADE officers, and the nominating committee. Diabetes Health wishes Board of Directors candidates and former DH Guest Editors, Jane Jeffrie Seley, Kim Higgins, and Deborah Greenwood, the best of luck.
1 comment - Posted May 19, 2009
Smoking increases the harmful effects of diabetes by increasing insulin resistance and worsening diabetes control. It raises the likelihood of microvascular and macrovascular complications associated with diabetes. The risk of death from heart disease and stroke is increased, as are the possibilities of neuropathy, nephropathy, and retinopathy.
3 comments - Posted May 12, 2009
Dear Sex & Diabetes, I have had type 1 diabetes since the age of ten. When my husband and I were first married, I had no trouble with my sex drive. After the births of our three children, however, I noticed a big decrease in desire. I have also had a hysterectomy and have gained 50 pounds since we were first married. Do you think my weight has something to do with it? I really don't feel it is fair to put my husband through my lack of desire. He still seems to want me.
2 comments - Posted May 12, 2009
The U.S. Food and Drug Administration has just approved the marketing of Cycloset, a type 2 diabetes drug that works by affecting a brain chemical that helps govern metabolism. In doing so, it helps reduce the rise in blood sugar levels that typically occurs after meals. Cycloset will be offered as a monotherapy or in conjunction with sulfonylureas, metformin, or other combination type 2 drug therapies.
2 comments - Posted May 12, 2009
After American and Brazilian researchers implanted 23 newly diagnosed type 1 patients with their own adult stem cells, 12 of the patients became insulin-free for periods lasting from 14 to 52 months (the mean was 31 months).
16 comments - Posted May 12, 2009
It has been an interesting month for San Diego-based Amylin Pharmaceuticals Inc., the co-manufacturer of Byetta (exenatide) with Eli Lilly & Co., and Alkermes Inc. First, the company announced that it will reduce its sales force by 35 percent-200 employees-in hope of saving $20 million this year and $45 million annually starting in 2010. The company plans to retain 325 representatives to sell its diabetes products to doctors and endocrinologists. At the same time, Amylin has petitioned the FDA to approve the marketing of Byetta LAR, a form of the type 2 drug that requires injection only once a week.
1 comment - Posted May 11, 2009
Rachel Humphrey, a Manhattan Beach, CA, teenager with type 1 diabetes, was granted her biggest wish (well, almost) when she came face to face with her hero, Nick Jonas of the Jonas Brothers. Rachel, 13, was selected to appear on the number 1 new syndicated talk show, "The Doctors," but she had no idea that she would meet Nick Jonas on the set! The segment, titled Giving is Good Medicine, will air on Friday, May 8th.
8 comments - Posted May 8, 2009
The European Union's drug regulation agency has recommended that the EU approve the marketing of "Victoza" (liraglutide), a type 2 drug developed by Novo Nordisk.
2 comments - Posted May 6, 2009
Voglibose*, a generic drug often used in combination with sulfonylureas to control blood glucose levels, appears to delay or even prevent the onset of diabetes in people who are predisposed to the disease.
6 comments - Posted May 1, 2009
April 2009
What do you eat in a 140 mile Ironman triathlon? I get that question a lot. It's been said that the Ironman race is 10% fitness, and 90% nutrition. That's a bit of an exaggeration, but for those of us with diabetes, that's our daily life. Nutrition affects everything we do. Exercise, sleep, driving a car, all of those activities require a person with diabetes to think about the carbohydrates they have consumed and when they will eat or drink them again
2 comments - Posted Apr 30, 2009
When Smiths Medical announced in late March that it was discontinuing the manufacture and sales of its Deltec Cozmo insulin pumps, the company's annual sales of that product were about $36 million. In contrast, Medtronic, manufacturer of the Minimed line of insulin pumps reported sales of $727 million in the nine months from April 2008 to January 2009.
8 comments - Posted Apr 29, 2009
Although researchers reporting the phenomenon can't quite put their fingers on how it works, a newly released study says that severe hypoglycemic episodes requiring hospitalization among older people with type 2 diabetes create a greater risk - 32 percent - for developing dementia.
1 comment - Posted Apr 29, 2009
Insulin pens have been very popular in Europe for quite some time and interest is building steadily in the United States. Many people prefer an insulin pen over the standard syringe and vial because the pens are more convenient and more accurate. Pre-filled disposable insulin pens are the easiest of all, because you don't never have to install a new cartridge when the pen is empty-you just toss it out.
4 comments - Posted Apr 28, 2009
Many people with diabetes who have ditched multiple daily injections in exchange for an insulin pump regret not doing so sooner. Ask them why they didn't, and arguably the most common answer has something to do with vanity. Still, while many might feel overjoyed by their optimum blood sugar control, they're not in love with their new appendage and may struggle with self-image as a result.
1 comment - Posted Apr 25, 2009
Women hate their bodies. At least, an overwhelming collection of statistical data suggests as much. Consider the following facts compiled by Liz Dittrich, Ph.D, at About-Face.org, which aims to combat negative and distorted images of women:
0 comments - Posted Apr 24, 2009
Long before Joy Pape, RN, BSN, CDE, WOCN, CFCN, served a stint as the clinical editor and contributing columnist for Diabetes Health Professional, she was a seasoned diabetes expert who knew her way around almost every aspect of the disease.
0 comments - Posted Apr 22, 2009
Well, this is a surprise. The Medicare Prescription Drug, Improvement, and Modernization Act (MMA) of 2003 contains a little known section, Section 1013, that has actually led to something really useful: Up-to-date information about diabetes culled from real research and presented in language that we all can understand. Section 1013 authorizes the Agency for Healthcare Research and Quality (AHRQ) to compare the effectiveness of different approaches to difficult health problems and to make that information accessible and understandable to "decisionmakers": that is, you, me, and our doctors. And diabetes is one of the difficult health problems to which the AHRQ is directing its attention.
2 comments - Posted Apr 21, 2009
The need to investigate and determine normoglycemia in Mexican children under the age of six begins with a lack of relevant published data. Another motive for reviewing the currently recommended glycemic goals for children and adolescents with type 1 stems from the well-known observation that children and adolescents who do not have type 1 do not develop microvascular diabetic complications. Today, thanks to insulin analogs and basal/bolus therapy regimens, children with type 1 have the option of achieving true euglycemia and of potentially benefiting from its advantages.
14 comments - Posted Apr 17, 2009
There is an old schoolyard chant that starts out with an image of two people "sitting in a tree" and "K-I-S-S-I-N-G." This is followed by, "First comes love, then comes marriage, then comes the baby in the baby carriage." The natural progression of life is to find one's "soul mate," tie the knot, and then have children.
37 comments - Posted Apr 17, 2009
Understanding which proteins help control blood glucose during and after exercise could lead to new drug therapies or more effective exercise to prevent type 2 diabetes and other health problems associated with high blood sugar.
0 comments - Posted Apr 16, 2009
Results from DURATION-2, a 26-week test comparing the diabetic drugs Januvia, Actos, and experimental long-acting Byetta (Byetta LAR) show that Byetta produced lower A1c's and more weight loss than the other two drugs.
5 comments - Posted Apr 15, 2009
Has your doctor told you that you have impaired fasting glucose? That means that the glucose level in your blood, after you haven’t eaten for at least eight hours, is still higher than 100 milligrams of glucose per deciliter of blood. In other words, your blood is too sweet because your insulin is not clearing the sugar out of your blood very well. You have pre-diabetes.
0 comments - Posted Apr 10, 2009
Buoyed by its recent successful phase 1 human clinical trial of a patch that delivers basal insulin through the skin, Atlanta-based Altea Therapeutics says it will work with Eli Lilly and Company and Amylin Pharmaceuticals, Inc., to develop a daily transdermal patch that deliver sustained levels of Byetta (exenatide). The patch, in a 12- and a 24-hour form, will use the company's proprietary PassPort Transdermal Delivery System. Lilly and Amylin will fund all development, manufacturing, and marketing activities for the product.
2 comments - Posted Apr 7, 2009
A new research report by the Pacific Research Institute (PRI) reviews three decades of the Food and Drug Administration's performance and concludes that the agency is over-funded, over-staffed, and denies hundreds of thousands of Americans timely access to new medicines. Leviathan's Drug Problem: The Federal Monopoly of Pharmaceutical Regulation and Its Deadly Cost was authored by John R. Graham, Director of Health Care Studies at PRI.
5 comments - Posted Apr 7, 2009
Being overweight is something all doctors and most laypeople know significantly increases the risk of acquiring type 2 diabetes. In fact, the American Diabetes Association (ADA) says that more than 90 percent of people who are newly diagnosed with type 2 are overweight. But why does excess fat increase the risk of diabetes? Isn't the disease, after all, one that involves the body's inability to metabolize glucose?
3 comments - Posted Apr 2, 2009
My whole childhood, I was a bit of a pudgy girl. At the age of eight, I weighed over 110 pounds, wore a woman's size 8, and stood a mere five feet tall. I wasn't grossly obese, by any means, but it was enough to keep me off the cheerleading squad and out of the popular crowd at school. I didn't really have any health issues besides the weight.
27 comments - Posted Apr 1, 2009
March 2009
The American Diabetes Association (ADA) and American Association of Clinical Endocrinologists (AACE) released a statement last week in response to the study published online in the New England Journal of Medicine which suggested that intensive blood glucose control for critical care patients with hyperglycemia doesn't improve outcomes and is associated with an increase in deaths.
1 comment - Posted Mar 31, 2009
One of the most impressive feats of endurance in the animal world is performed by the sled dogs that run up to 100 miles per day in such races as Alaska's Iditarod, a grueling 1,161-mile trek from Simpson to Homer.
0 comments - Posted Mar 31, 2009
I hear voices in my surroundings as the cloud of confusion gradually begins to lift. "Curtis, can you hear me?" "Curtis, what was the score of the football game?" "Curtis, do you know where you are?"
5 comments - Posted Mar 27, 2009
The first time Chris Matthews heard the words "high blood sugar" was in 2002 at a doctor's office in Washington, DC, where he was being treated for malaria after a trip to Zimbabwe. He didn't pay a lot of attention to the warning about his glucose levels after a blood test. The malaria was subsequently cured, and he continued at his usual rapid-fire pace, traveling the country giving speeches about his best-selling books ("Life is a Campaign" is his latest; "Hardball" is his best known) and his work both inside the White House, where he was a speechwriter for President Carter, and outside, where he was administrative assistant to House Speaker Tip O'Neill on Capitol Hill. Then there's his work on television, where he is host of Hardball on MSNBC and the Chris Matthew Show, which airs on Sundays just before Meet the Press on NBC. He stayed busy, and his schedule remained overbooked. He let the warning about high blood sugar go into the background-so far back it was out of sight and definitely out of mind. Besides, there just wasn't any room in his life to deal with it.
10 comments - Posted Mar 26, 2009
If you fancy cat naps and think that they might be a handy way to circumvent the ill effects of too little sleep at night (see Sleeping Less Than 6 Hours a Night? Your Risk of Developing a Type 2 Precursor Is Nearly 5x Higher), think again: A British study of the napping habits of more than 16,000 people in China has concluded that taking a nap even once a week can increase your risk of developing type 2 diabetes by 26 percent over people who never take naps.
7 comments - Posted Mar 25, 2009
If you get less than six hours of sleep per night, your risk of developing impaired fasting glucose rises by a factor of 4.56, according to a report from the American Heart Association.
2 comments - Posted Mar 25, 2009
The FDA has announced that starting in early April, its Endocrinologic and Metabolic Drugs Advisory Committee will begin looking into two new drugs for type 2 diabetes: saxagliptin tablets from Bristol-Meyers Squibb and liraglutide, an injection drug from Novo Nordisk.
1 comment - Posted Mar 24, 2009
In a study funded by Novo Nordisk, researchers at Ohio State University have found that type 2s who move from oral meds to insulin would be wise to start with an insulin pen rather than a syringe.
16 comments - Posted Mar 21, 2009
Physicians who treat people with type 2 diabetes face difficult choices when selecting the best medical therapy for each patient. The decision process is further complicated by the fact that because type 2 diabetes is a progressive disease, therapeutic agents that were initially successful may fail five or ten years later.
162 comments - Posted Mar 20, 2009
Sanofi-aventis U.S., a maker of insulin as well as many other pharmaceuticals, announced last month the launch of their new YouTube diabetes channel that's designed to challenge the barriers, myths, and misperceptions about insulin use and empower people living with type 2 diabetes to make better-informed decisions for managing their condition. The channel is part of their broader GoInsulin campaign, a multi-media resource for people living with type 2 diabetes to help dispel the myths about insulin.
0 comments - Posted Mar 19, 2009
New cases of adult type 2 diabetes have increased by more than 90 percent in the past 10 years, according to recent data from the Centers for Disease and Prevention.(1) Equally troubling is the dramatic rise in type 2 diabetes among children. Recent reports reveal a 200 percent increase in hospitalizations for children with type 2 diabetes, a condition that was rarely diagnosed in children decades ago.(2) In the words of the CDC, "Diabetes is common, disabling, and deadly."(3)
2 comments - Posted Mar 18, 2009
Novo Nordisk has redesigned the FlexPen®, the number one selling pre-filled insulin pen in the world, to not only require less force when pushing the button to inject insulin, but also to clearly identify each type of insulin with prominent color branding. The FlexPen® is available with three Novo Nordisk insulin products: Levemir® (insulin detemir [rDNA origin] injection); NovoLog® (insulin aspart [rDNA origin] injection); and NovoLog® Mix 70/30 (70% insulin aspart protamine suspension and 30% insulin aspart injection, [rDNA origin]).
6 comments - Posted Mar 18, 2009
Obesity has long been accepted as a risk factor for diabetes. The results of four recently published studies, however, have revealed that the real risk factor may be the insecticides present in that fat. The initial investigations showed that the expected association between obesity and diabetes/insulin resistance was absent in people who had low levels of organochlorine insecticides in their blood (1, 2). However, the expected association between obesity and diabetes/insulin resistance increased with levels of these insecticides. In the last year, two additional studies have linked these insecticides with diabetes (3, 4).
10 comments - Posted Mar 13, 2009
Researchers funded by the Juvenile Diabetes Research Foundation have found two chemical compounds that can trigger the growth of insulin-producing beta cells in the pancreas. The discovery could become the basis for medicines designed to regenerate the pancreas in people with type 1 diabetes.
9 comments - Posted Mar 11, 2009
Whenever Diabetes Health publishes an article about high fructose corn syrup (HFCS), we receive mountains of printed material from corn industry advocates. They argue that the effects of HFCS cannot be extrapolated from research because the "studies look at the effects of fructose independently." They claim, in the words of Christopher Mohr, MS, RD, LDN, of the Corn Refiners Association, that "the absence of glucose makes pure fructose fundamentally different from HFCS."
14 comments - Posted Mar 11, 2009
It was in the spring of 2005 that I received a call from the director of the diabetes camp in the state where I lived and worked as a sales rep for a blood glucose meter company. He was calling to ask if I would volunteer as a counselor at the week-long camp, which served around 200 campers, the vast majority with type 1 diabetes. I'd known for years that counselors were always in demand at the camp, but had never stepped forward to volunteer. I'd heard the stories of how tough and exhausting it was keeping up with your group, performing 2:00 AM blood sugar checks, and ensuring that they all stayed safe and had fun. Frankly, I'd always had serious doubts as to whether I was up to it. This, however, was the first time that I had been directly asked to volunteer, and something inside me made me grudgingly agree. As I drove to the campsite to begin that week in June, though, I'd be lying if I did not admit to being as nervous as any of the kids who were attending.
5 comments - Posted Mar 6, 2009
Chances are that you know somebody who can pack away the highest-fat foods-marbled steak, cheese, butter, and ice cream-and never gain weight. If you've always shrugged it off and said, "It must be genetic," it turns out that you may be right.
2 comments - Posted Mar 5, 2009
A few quick, intense bursts of energy, such as 7.5 minutes per week of sprints on a stationary bicycle, may be just as good as 30 minutes per day of moderate exercise in reducing the risk of type 2 diabetes. In fact, say researchers at Heriot-Watt University in Edinburgh, Scotland, such short bursts may be even more effective.
2 comments - Posted Mar 5, 2009
I was diagnosed with type 1 relatively late in life, at age 24. People sometimes remark to me, with genuine kindness, that it must have been harder on me. Perhaps they think I recall what it was like to be a "normal" child and young adult, to do and eat what I wanted without insulin, checking blood sugar, or worrying about highs and lows or long-term complications. I appreciate their sincerity, but I always correct them. Diabetes is not harder for me. It is hard on everyone. Whether you were diagnosed as a child or an adult, it complicates your life and the lives of your family.
1 comment - Posted Mar 4, 2009
A complex sugar derived from glucose during the body’s metabolic processes could be a way to reliably detect a pre-diabetes condition, say researchers at the Johns Hopkins University School of Medicine in Baltimore. If it does, the “biomarker” (an indicator of an organism’s state of health) could provide enough early warning that patients nearing the onset of type 2 diabetes could take steps to slow or even halt it through lifestyle changes.
1 comment - Posted Mar 3, 2009
A few years ago a young man named Jeff came into my office seeking help to lose weight. He was 5'10" tall and weighed 130 pounds. Jeff denied starving himself, denied making himself throw up, and denied over-exercising. I tried to convince him that he was actually 30 pounds underweight. As I looked for the most effective ways of motivating him to restore his health, he brought up the fact that he had type 1 diabetes. Jeff said that he rarely gave himself insulin and that he had "diabulimia." I had never heard of diabulimia and had no idea what I was dealing with. I gave him a list of clinicians and asked him to call me back after he made appointments with an endocrinologist and a psychotherapist.
13 comments - Posted Mar 3, 2009
February 2009
Do infusion sets refuse to stick to your skin?
7 comments - Posted Feb 27, 2009
DM-99, a drug under development by the Canadian drug company DiaMedica, Inc., has just finished a phase 2a "proof of concept" trial with 40 type 2 patients in Europe. Although the company did not release performance figures from the trial, it found them sufficiently encouraging to move further into phase 2 testing.
0 comments - Posted Feb 26, 2009
A report in the February 4, 2009, issue of Cell Metabolism says that babies born with neonatal diabetes might be able to avoid irreversible damage to the pancreas if doctors treat them quickly with sulfonylureas rather than insulin.
0 comments - Posted Feb 25, 2009
Georgia researchers believe that a powerful enzyme that inhibits or modifies immune system response could be the basis for a vaccine administered to children at high risk for developing type 1 diabetes.
0 comments - Posted Feb 25, 2009
I admit it: I've had diabetes for seven years, and only recently did I even think about buying a medical alert ID. It's not like me to be this irresponsible, but diabetes crept up on me, rather like type 2 does, although I'm a type 1. My diabetes is a slowly progressing adult-onset form, sometimes called type 1.5. For the first five years after my diagnosis, I controlled the disease with diet.
12 comments - Posted Feb 24, 2009
Data from a phase 3 study of the Novo Nordisk drug liraglutide shows that when it is used in combination with glimepiride, it is more effective at reducing A1c's than glimepiride by itself or glimepiride in combination with the drug rosiglitazone.
0 comments - Posted Feb 19, 2009
Sanofi-aventis U.S. and Children with Diabetes have announced the arrival of a multimedia resource, called the KidCare Kit, which gives families the tools and information they need to get through the challenging first 30 days after a diagnosis of type 1.
0 comments - Posted Feb 18, 2009
Over the past few years, Team Type 1, a team of elite and professional cyclists living with type 1 diabetes, has competed in races like the Tour of Georgia and the AT&T Austin Downtown Criterium, and it has twice won the ultra-endurance, 3,052 mile Race Across America (RAAM).
0 comments - Posted Feb 18, 2009
Editor's note: We recently received the following heartbreaking letter. The article that follows was first published in May, 2006. Little has changed.
13 comments - Posted Feb 12, 2009
Keep this letter-number sequence in mind: CXCL10. You'll probably be reading a lot more about it.
1 comment - Posted Feb 11, 2009
Remember that public service advertisement that showed a frying egg and then announced, "This is your brain on drugs"? Well, now American researchers think that insulin might be able to shield that brain from the ravages of Alzheimer's disease.
1 comment - Posted Feb 10, 2009
Cards, gifts, chocolates, flowers, and romantic gestures. Isn't that what Valentine's Day is supposed to be about? My husband Brian and I had been going on that theory until 2002, when the holiday had the audacity to come around again one month after our son Danny was diagnosed with diabetes. That year, we woke up, wished each other Happy Valentine's Day and started talking about blood sugar levels, carbohydrates, insulin, exercise and pharmacies. We hit those same topics during the day by phone, and although we vaguely planned to go out for dinner, by evening Danny wasn't feeling well, and we spent part of the night on the phone to Children's Hospital. We did remember to kiss goodnight before we collapsed into a restless sleep, but were poised for the alarm to wake us, so we could test Danny's blood sugar levels again at midnight.
4 comments - Posted Feb 9, 2009
Baxter International, Inc., which produces the peritoneal dialysis solution Extraneal (icodextrin), has teamed with MedicAlert Foundation International to encourage peritoneal dialysis patients to add a warning to their MedicAlert bracelets regarding the fact that icodextrin may cause false readings on non-specific glucose monitors.
0 comments - Posted Feb 5, 2009
By introducing a protein called cdk6 into human insulin-producing adult beta cells via a virus, University of Pittsburgh School of Medicine researchers have induced the cells to replicate "robustly." Previously, scientists believed that beta cells could be induced to regenerate slowly at best, and usually not at all.
0 comments - Posted Feb 5, 2009
Asia, which covers an area almost twice the size of North America and is home to three billion people-half of humanity-is often seen as a homogenous entity in the minds of many Westerners, even scientists. But a land that stretches 6,000 miles from east to west is anything but homogenous. The Israelis and Arabs in western Asia, for example, are far different ethnically from the Hmong mountain people in Southeast Asia, the Ainu in northern Japan, or the Filipinos in the southwestern Pacific.
0 comments - Posted Feb 3, 2009
Cards, gifts, chocolates, flowers, and romantic gestures. Isn't that what Valentine's Day is supposed to be about? My husband Brian and I had been going on that theory until 2002, when the holiday had the audacity to come around one month after our son Danny was diagnosed with diabetes. That year, we woke up, wished each other Happy Valentine's Day, and started talking about blood sugar levels, carbohydrates, insulin, exercise, and pharmacies. We hit those same topics during the day by phone, and although we vaguely planned to go out for dinner, by evening Danny wasn't feeling well, and we spent part of the night on the phone to Children's Hospital. We did remember to kiss goodnight before we collapsed into a restless sleep, but were poised for the alarm to wake us so we could test Danny's blood sugar levels again at midnight.
0 comments - Posted Feb 1, 2009
January 2009
A study published in the Journal of Hospital Medicine has found that the glucose control practices at academic medical centers are below par and fail to meet the current standards set by the American Diabetes Association (ADA).
2 comments - Posted Jan 30, 2009
Air polluted with particulate matter at concentrations found in many U.S. metro areas may be a contributing factor in obesity and to the onset of diabetes, say researchers at the Ohio State University Medical Center.
0 comments - Posted Jan 29, 2009
Syracuse University chemist Robert Doyle has taken out a patent on something that has long been a Holy Grail for insulin suppliers and users: a reliable way to take insulin orally instead of with a needle.
4 comments - Posted Jan 28, 2009
The appearance of professional football player William "Refrigerator" Perry used to bother me. It was clear that he had been encouraged to get really big, and I worried about all that extra weight he carried. There were others almost as heavy, of course, but the Fridge was especially likable-he had charisma and an obvious sense of humor. (For fun, he once boxed 7-foot, 7-inch super-skinny former NBA player Manute Bol. He even entered the 2003 Nathan's Famous Fourth of July Hot Dog Eating Contest, coming in about 40 hot dogs behind the winner.) I worried about his health.
0 comments - Posted Jan 28, 2009
Remember that New Year's resolution that you made a few weeks ago? Oh yeah, that one. How's that going? If you're like most people, you may have started to slack off just a little bit. Or even worse, maybe it's already a distant memory. No worries, I won't tell. Let's get you going again.
1 comment - Posted Jan 27, 2009
We first reported on salsalate, an aspirin-like drug discovered in the nineteenth century, last October. At that time, researchers at the Joslin Diabetes Center in Boston discovered that it appears to reduce inflammation and lower blood glucose in people with type 2 diabetes.
2 comments - Posted Jan 27, 2009
Nearly every time that I mention islet transplantation in a conversation about diabetes, the person I'm with responds with a sniff that it's never going to work because of the immune suppression problem.
12 comments - Posted Jan 24, 2009
Hearts in the medical community beat with considerable excitement at the discovery of leptin in 1994. A hormone produced by fat, leptin has a very useful talent: it tells the brain when to stop eating. So hopes were high that leptin would become the basis of an anti-obesity treatment. What could be simpler than to dose an obese person with a hormone that says, "You're not hungry any more, and you want to stop eating."
0 comments - Posted Jan 22, 2009
The treatment of diabetes has come a long way since Dr. Elliot Joslin wrote The Treatment of Diabetes Mellitus in 1916. But Dr. Joslin's idea that diet, exercise, and insulin (when it became available as therapy in 1922) are the keys to managing diabetes remains true today. This doesn't mean that diabetes is not a complex illness requiring ongoing education and individualized care. People with diabetes benefit greatly from the services of a team of health care professionals including a certified diabetes educator and an endocrinologist--a doctor who specializes in treating disorders of the endocrine system.
7 comments - Posted Jan 21, 2009
You've been diagnosed with diabetes because there is too much glucose (a kind of sugar) in your blood.
7 comments - Posted Jan 16, 2009
Tell this to your non-diabetic friends and relatives: The next time they look in a full-length mirror, they shouldn't be too quick to dismiss their ample hips and bottoms.
0 comments - Posted Jan 16, 2009
As the 76-million-member Baby Boomer generation ages-its oldest members are now 63-nursing homes are bracing for an unprecedented demand for their services. Along with increased pressure from the sheer number of patients, nursing homes will also have to deal with the skyrocketing number of seniors with type 2 diabetes.
2 comments - Posted Jan 15, 2009
According to biologists at the Baylor College of Medicine, limiting the copies of a gene that produces a protein affecting organ development serves to decrease fat cell size in mice, enhance their responsiveness to insulin, and increase their energy level.
0 comments - Posted Jan 14, 2009
Two diets - one severely restricting carbohydrate intake but with no limit on calories, and the other emphasizing low-glycemic carbohydrates and low calories - allowed high percentages of obese type 2 patients in a university study to reduce or even eliminate their diabetes medications (95.2 percent of the patients on the extreme low-carb diet and 62.1 percent of the patients on the low-glycemic diet).
6 comments - Posted Jan 14, 2009
About half of young people who have diabetes report having tried to lose weight at one time or another, says a Kaiser Permanente Southern California study reported in the December 2008 issue of Diabetes Care.
4 comments - Posted Jan 6, 2009
They start in your forties as periodic mental hiccups where you suddenly lose the thread of a thought. By your fifties, they happen often enough to make you jokingly introduce the phase "senior moment" to your vocabulary. And by the time you enter your sixties, there's not a lot of humor in them any more. Senior moments become an often exasperating stall in conversations and thought.
0 comments - Posted Jan 6, 2009
In a recent study, obese teens with type 2 diabetes who underwent gastric bypass surgery not only lost a third of their weight, but also experienced the complete remission of their disease.
4 comments - Posted Jan 6, 2009
December 2008
Every type 1 fears having a hypoglycemic event. Because people are usually more accustomed to dealing with highs, however, a sudden low often catches them unaware. Use this fictional yet typical story to find out what might happen medically during a low and what you need to know to keep hypoglycemia in check.
10 comments - Posted Dec 29, 2008
Every year the American Diabetes Associations revises and updates its Clinical Practice Recommendations, a publication upon which many doctors and medical caregivers depend as a primary source of diabetes treatment information.
12 comments - Posted Dec 29, 2008
A study of the effectiveness of the drug terbutaline on controlling nighttime hypoglycemia in people with type 1 diabetes indicates that it may be a safe and useful treatment with no ill effects.
5 comments - Posted Dec 29, 2008
Diabetes may be described as a disease of glucose intolerance: high blood glucose is both the characteristic indicator and the cause of complications.
120 comments - Posted Dec 25, 2008
About a year ago, Cheryl Tooke found herself in the last place she ever wanted to be. She weighed 268 pounds, and her doctor had just diagnosed her with type 2 diabetes.
84 comments - Posted Dec 25, 2008
The Chinese mentioned cinnamon in their written work more than 4,000 years ago. The ancient Egyptians used cinnamon in their embalming process, and the Roman writer/philosopher Pliny the Elder wrote in the first century AD that cinnamon was worth 15 times more than silver of the same weight.
43 comments - Posted Dec 25, 2008
Sandy was giving her son his evening dose of NPH insulin - something she had done many times. But as she finished pushing in the plunger, she said to herself, "That shot took too long." She immediately realized that she had given Joey the wrong dose. In other words, by mistake, she had given him a potentially lethal dose of insulin.
61 comments - Posted Dec 25, 2008
Obesity in the United States is increasing in epidemic proportions. This is true in children as well as adults. It's estimated that the healthcare costs associated with obesity and its related complications will exceed $130 billion this year.
52 comments - Posted Dec 25, 2008
No less an authority than the New York Times wrote in May 2006 that Halle Berry has type 1 diabetes, listing her as one of several "stars who have type 1 - Gary Hall, the Olympic gold medal-winning swimmer; Adam Morrison, the Gonzaga University basketball star; [and] Halle Berry."
69 comments - Posted Dec 25, 2008
The day I heard "Diabetes is not the leading cause of heart attack, blindness, kidney disease, and amputation," my life changed. I had believed the opposite to be true for the 32 years I'd been dealing with diabetes. Complications had always hung like a knife over my head.
14 comments - Posted Dec 22, 2008
A Spanish university study has found that a traditional Mediterranean diet consisting of fruits, vegetables, whole grains, olive oil, and fish may reduce the risk of acquiring type 2 diabetes by 83 percent.
1 comment - Posted Dec 22, 2008
Avandia (rosiglitazone) and Actos (pioglitazone), two medications used to lower blood sugar in type 2 patients, double the risk of fractures in women, but not in men, says a new study.
0 comments - Posted Dec 22, 2008
"Inspired by Diabetes" is a friendly competition that not only helps people with diabetes gain inspiration from each other, but also generates donations to diabetes treatment centers in developing countries.
3 comments - Posted Dec 22, 2008
The U.S. Food and Drug Administration has recommended that companies manufacturing diabetes treatment drugs provide evidence that their products will not increase cardiovascular risks.
0 comments - Posted Dec 22, 2008
Finnish scientists have reported that children who develop type 1 diabetes experience disturbances in their lipid and amino acid metabolism months or years before the onset of the disease. Their finding of distinct markers that precede the disease could lead to treatments designed to prevent the body's autoimmune system from attacking the pancreatic insulin-producing cells.
0 comments - Posted Dec 22, 2008
A common treatment for obstructive sleep apnea (OSA) decreased the average glucose level during sleep of type 2s who were newly diagnosed with OSA. After seven weeks of the therapy, known as continuous positive airway pressure (CPAP), the diabetic patients' average BG level fell 20 mg/dl.
1 comment - Posted Dec 22, 2008
For 2,000 years diabetes has been recognized as a devastating and deadly disease. In the first century A.D. a Greek, Aretaeus, described the destructive nature of the affliction which he named "diabetes" from the Greek word for "siphon." Eugene J. Leopold in his text Aretaeus the Cappodacian describes Aretaeus' diagnosis: "...For fluids do not remain in the body, but use the body only as a channel through which they may flow out. Life lasts only for a time, but not very long. For they urinate with pain and painful is the emaciation. For no essential part of the drink is absorbed by the body while great masses of the flesh are liquefied into urine."
45 comments - Posted Dec 17, 2008
Take this test on insulin and see if you can get a higher score than hospital doctors and nurses.
19 comments - Posted Dec 17, 2008
When the sun rose that morning, I was in the kitchen as usual with my daughter, preparing to take my insulin. I usually don't take it in front of her, but we were engaged in one of those frustrating conversations that were so common now that she was a teenager.
20 comments - Posted Dec 17, 2008
It has been rags to riches for singer Elliott Yamin. With his naturally soulful singing voice, listeners feel his raw emotion and they like it. When you hear him, you know immediately that few guys in any musical genre sing with this kind of authenticity.
29 comments - Posted Dec 17, 2008
Most people with diabetes will tell you this: Everything about having it is a hassle, an annoyance and sometimes utterly overwhelming. Endless worrying over meal plans, carbohydrate counting, finger-stick checks, pills, injections, lab tests, prescriptions, supplies and doctors’ appointments are nobody’s idea of fun.
7 comments - Posted Dec 17, 2008
Bob Cleveland wondered if he’d live when he went to the hospital as a 5-year-old. In 1925, hospital visits were made for dire reasons.
3 comments - Posted Dec 17, 2008
Until fairly recently, low testosterone in men (I call it "low T") was treated only in patients with severe and obvious T deficiencies, such as men with congenital hormonal conditions that affected their pituitary gland or those who had lost both testicles to trauma, tumors, or infections. However, as the medical community has learned more about the benefits of T therapy for men with less obvious causes of low T (e.g., improved sexual desire and function, energy, and body composition), there has been concomitant interest in how T relates to other medical conditions, including diabetes. It turns out that the relationship between low T and diabetes is quite involved, although the final chapter on the ultimate nature of the relationship is still to be written.
1 comment - Posted Dec 15, 2008
Hopes that the U.S. Food and Drug Administration would move soon to make the diabetes drug Byetta a monotherapy are fading. It now appears that the FDA will extend its review of the drug into 2009.
5 comments - Posted Dec 15, 2008
An international team of researchers reports that a mutation in a gene that controls a person's body clock can cause higher blood sugar levels, leading to a 20 percent increased risk of acquiring type 2 diabetes.
0 comments - Posted Dec 15, 2008
Many people think of heart disease as something that mostly afflicts men. But heart disease actually kills more women in the United States than anything else, according to the National Heart, Lung and Blood Institute. And diabetes plays a stronger role in risk for heart disease in women than it does in men.
1 comment - Posted Dec 15, 2008
Are you ready to celebrate the holidays? How many festivities are on your calendar this season? It’s time to navigate the minefield of situations that can throw your diabetes off course and send a joyous occasion into the dumps.
0 comments - Posted Dec 10, 2008
Need gift ideas? Holiday gift-giving can be a challenge. Some people like surprise gifts, some make “must have” or “wish” lists. I don’t always know what is on someone’s list, or if they would enjoy a surprise.
1 comment - Posted Dec 10, 2008
The first time I presented medical research findings, I was not yet a physician. The year was about 1975. I was in my early forties and a mid-career engineer. The forum was a scientific symposium on diabetes. At the time, I felt that I had discovered the holy grail of diabetes care and was eager to share what I had learned.
22 comments - Posted Dec 8, 2008
Older men who are worried about insulin resistance can take heart from a Tufts University study which shows that higher than normal doses of vitamin K slow development of the condition. (Insulin resistance is a condition in which the body increasingly cannot use insulin properly and blood glucose levels rise. It is a major precursor to type 2 diabetes.)
1 comment - Posted Dec 8, 2008
More than 60 percent of adults with type 1 diabetes are not physically active, according to a study in the November 2008 issue of Diabetes Care. Their reason is fear that exercise will bring on hypoglycemia, leading to such severe consequences as loss of consciousness or even death.
2 comments - Posted Dec 8, 2008
If you're like millions of type 2s and people being treated for metabolic syndrome, you take metformin to control your liver's glucose production.
0 comments - Posted Dec 8, 2008
My daughter Lauren was five days shy of her twelfth birthday when she was diagnosed with type 1. We were blessed with a child who could and did take the lead in her recovery and care. She never had any "teen diabetic rebellion" and never adopted a "why me?" mentality. Her health has been great, and her last A1c was 6.7%. With all the hormonal changes that can affect a teenage girl's body and thus change her insulin requirements, Lauren has always stayed on top of her care and never lost her fantastic personality.
24 comments - Posted Dec 2, 2008
Next week we'll publish a great article written by Dr. Richard Bernstein. MD. Dr. Bernstein is a long-term proponent of paying more attention to carbs rather than fats (though he certainly doesn't advocate that you can have all the fats you want!) While Dr. Bernstein has been telling us about the benefits of low carb for over 30 years, there is still much skepticism about his (and many other's-Gary Taubes, anyone?) low carb results. The establishment has been slow to be convinced, despite the many research trials that back up their findings.
6 comments - Posted Dec 2, 2008
Non-beta "progenitor" cells in the pancreas can be stimulated to turn into beta cells even after birth or autoimmune injury to the pancreas, say researchers at Joslin Diabetes Center in Boston, an affiliate of Harvard Medical School.
2 comments - Posted Dec 2, 2008
Last week we published an excerpt from Chapter 4 of Sheri Colberg's revised, updated, and expanded version of her 2001 book, Diabetic Athlete's Handbook: Your Guide to Peak Performance. Dr. Colberg has a PhD in exercise physiology, is a Diabetes Health board member, and is herself an athlete with diabetes. Her book draws upon the experiences of hundreds of athletes with diabetes to provide the best advice for exercisers with diabetes, either type 1 or type 2.
0 comments - Posted Dec 2, 2008
One of the most promising approaches to the treatment of type 1 diabetes is the transplantation of human islet cells. The major drawback to the procedure has been that even though recipients initially enjoy revitalized pancreases that pump out copious amounts of insulin, their immune systems soon act as spoilsports and reject the donated cells.
0 comments - Posted Dec 2, 2008
November 2008
Diabetes Health board member Sheri Colberg, PhD, has published a completely revised, updated, and expanded version of her 2001 book, Diabetic Athlete's Handbook: Your Guide to Peak Performance. Dr. Colberg, a diabetic athlete herself, has a PhD in exercise physiology. Her book draws upon the experiences of hundreds of athletes with diabetes to provide the best advice for exercisers with diabetes, either type 1 or type 2.
2 comments - Posted Nov 24, 2008
A Superior Court judge in Sacramento has overturned a 2007 ruling that allowed trained school staff, not just registered nurses, to administer insulin shots to children with diabetes. The ruling affects approximately 14,000 California school children.
6 comments - Posted Nov 24, 2008
According to a study sponsored by Danish pharmaceutical company Novo Nordisk, it cost $218 billion to treat type 1 and 2 diabetes in the United States in 2007. Of that amount, the federal government spent approximately $85 billion.
1 comment - Posted Nov 24, 2008
I'll never forget the afternoon of January 22, 2003. I was just leaving my classroom when my phone lit up, alerting me to a new voicemail. My heart stopped when I listened to the message. It was my son's pediatrician, asking me to call him back as soon as possible.
2 comments - Posted Nov 24, 2008
No one knows better than people with diabetes how expensive prescription drugs are. A recent DH article reported that the annual cost for drugs to treat type 2 diabetes nearly doubled between 2001 and 2007, skyrocketing from $6.7 billion to $12.5 billion six years later.
3 comments - Posted Nov 17, 2008
Becoming pregnant for the first time can be overwhelming for any woman, especially if that woman has diabetes. When my husband and I decided we were ready to have children, the first thing I did was make an appointment with my endocrinologist. Diagnosed when I was fourteen, I've had type 1 diabetes for twenty-four years. My doctor explained that I would need to be in tight control for three months before I could even think about babies, so I got right to work. Learning everything I could about diabetes and pregnancy, I was pleased to discover that with education, support, and practice, a woman with diabetes has every opportunity for a healthy pregnancy.
7 comments - Posted Nov 17, 2008
Dear Laura,
I just finished viewing your clip online. You seem like a very intelligent and involved mom who decided it was time to take charge. I applaud you, and I agree with many points you make, but I disagree with your position on food.
11 comments - Posted Nov 17, 2008
With more than 2,500 facilities serving 10,000 communities that run the gamut from big-city downtowns to small rural sites, the YMCA (Young Men's Christian Association) could turn out to be a powerful tool in the fight to prevent diabetes.
1 comment - Posted Nov 17, 2008
As a child, I had an obsessive, irrational fear of going blind. At night, I lay in bed and kept opening my eyes every few minutes as I fell asleep to make sure I could still see, searching for outside lights filtering through the curtains of my bedroom window.
3 comments - Posted Nov 17, 2008
It turns out that donating your time to science isn't the ego booster we thought it was. There aren't a lot of thanks out there. A recent national survey of 900 adults found that while 84 percent of the public greatly admire organ donors and 68 percent greatly admire blood donors, a paltry 33 percent greatly admire people who participate in clinical trials.
2 comments - Posted Nov 17, 2008
Diabetes care creates its own culture. There is a passion that surrounds the caretakers of the diabetes community. It is the small successes that spark us to keep on until the next one. Diabetes care creates champions out of all of us. I'd like to mention just a few of the hundreds of diabetes educators I have met.
9 comments - Posted Nov 10, 2008
The U.S. Food and Drug Administration (FDA) has announced that Tyco Healthcare Group LP (Covidien) is recalling one lot of ReliOn sterile, single-use, disposable, hypodermic syringes with permanently affixed hypodermic needles due to possible mislabeling. The use of these syringes may lead to patients receiving an overdose of as much as 2.5 times the intended dose, which may lead to hypoglycemia, serious health consequences, and even death.
0 comments - Posted Nov 10, 2008
I have been reading a lot about diabetes on the Internet ever since I was diagnosed less than a year ago, and I wanted to share my experiences.
8 comments - Posted Nov 10, 2008
A study published in the August 25 Journal of the American Medical Association (JAMA) reports that people with type 1 diabetes "may not judge correctly when their blood sugar levels are too low and may consider driving with a low BG." In the study, "low" was defined as less than 70 mg/dl.
15 comments - Posted Nov 10, 2008
The FDA has approved the fast-acting insulin Apidra (insulin glulisine) for use in children four years and older who have type 1 diabetes.
1 comment - Posted Nov 3, 2008
Metformin, the tried-and-true diabetes drug that is prescribed to many type 2s when they are first diagnosed, may decrease the risk of death from cardiovascular disease. That's the conclusion of a meta-analysis by researchers at the Johns Hopkins Bloomberg School of Public Health in Baltimore, Maryland.
0 comments - Posted Nov 3, 2008
The annual cost for drugs to treat type 2 diabetes nearly doubled between 2001 and 20, skyrocketing from $6.7 billion in 2001 to $12.5 billion six years later, according to researchers from Stanford University and the University of Chicago.
0 comments - Posted Nov 3, 2008
When I was growing up in the South, my mother always told me, "You are what you eat." With Americans leading the pack in obesity and type 2 diabetes, it appears that she may have been right. Years of drive-through dinners and instant breakfasts have caught up with us, making us rethink every bite that passes our lips in our quest to fight off the complications of diabetes.
7 comments - Posted Nov 3, 2008
Even as diabetes researchers worldwide strive for total control over-or even an outright cure of-type 1 diabetes via gene therapy, altered cells, or surgical intervention, other researchers continue to press toward creation of a functional "artificial pancreas."
1 comment - Posted Nov 3, 2008
October 2008
David Kliff of Diabetic Investor was the first to report last week that Animas, the Johnson and Johnson unit that makes the OneTouch Ping blood glucose monitor, is recalling the Ping. The brand-new Ping received FDA clearance this past summer on July 1. According to reports, there is a small problem with the Ping that has nothing to do with the Animas 2020 insulin pump it works in concert with. The bolus calculator on the Ping does not work properly when it isn’t synched with the pump. When the two are synched, it works fine. Animas says the problem has been corrected and they are sending new units to customers to replace the defective ones.
0 comments - Posted Oct 27, 2008
If you use more than 200 units of insulin a day (or your child needs more than three units of insulin per kilogram of body weight per day), and you aren't reaching your blood glucose goals, you may want to consider U-500 insulin.
4 comments - Posted Oct 27, 2008
Pentoxifylline, a drug used to treat patients with circulation problems, may also benefit those with kidney disease caused by diabetes and other conditions. Specifically, pentoxifylline decreases proteinuria, the abnormal leakage of protein into the urine, according to two articles in the September issue of the American Journal of Kidney Diseases, the official journal of the National Kidney Foundation.
0 comments - Posted Oct 27, 2008
I read with interest the article by Cynthia Heinz in which she spoke to her local school board, describing a worst case scenario for a child with severe hypoglycemia. As a veteran parent with 15 years of dealing with diabetes in our local public school, I have a few things to add to the discussion.
9 comments - Posted Oct 27, 2008
A recent Wall Street Journal article shows once again how misinformation about diabetes-related topics can be spread by even the most expert journalists.
3 comments - Posted Oct 27, 2008
I have had type 1 diabetes for 16 years and, after a long path with many ups and downs, I have finally achieved optimal diabetic health. I have discovered the special lifestyle and diet mix that works and have brought my A1c from 11.4% to 5.2% while increasing my energy and overall health. I'm an elite athlete who plays professional ice hockey, and I currently run marathons.
19 comments - Posted Oct 27, 2008
Novo Nordisk recently announced results from its LEAD 6 study showing that once daily liraglutide was significantly more effective at improving blood glucose control (as measured by A1c) than exenatide, a GLP-1 mimetic administered twice daily.
4 comments - Posted Oct 27, 2008
A 55-year-old woman whose pancreas was removed due to chronic pancreatitis is not without a pancreas, thanks to the ingenuity of surgeons at the Methodist Hospital in Houston. After they removed her pancreas, they extracted its islet cells and implanted them into her left forearm, creating what they call a functioning pancreas in her arm. (Transplanted islet cells are usually injected into the liver, but in this case the patient's liver had damage that precluded its use.) Apparently the patient is recovering handily and should be armed with insulin as soon as the transplanted cells become fully functional.
3 comments - Posted Oct 20, 2008
Diabetes Health has always been ambivalent when it comes to reporting diabetes research that involves mice. For one thing, although the critters are mammals, it's a stretch to say that what happens in a mouse can be duplicated in a human.
6 comments - Posted Oct 20, 2008
An experimental exenatide (Byetta)-like drug called liraglutide has shown the ability to enhance insulin and glucagon production and suppress appetite in type 2 patients, according to a report in the British medical journal The Lancet.
0 comments - Posted Oct 13, 2008
An aspirin-like drug discovered 132 years ago may prove to be a powerful weapon against type 2 diabetes.
3 comments - Posted Oct 13, 2008
I rush to the hospital, hoping to get there in time. When I arrive, I find my newly diagnosed diabetic with a blood sugar of 1027. He is vomiting all over the place and might have a seizure soon. He is in diabetic ketoacidosis. It's time for my dream job.
5 comments - Posted Oct 13, 2008
The stock of Byetta manufacturer Amylin Pharmaceuticals has lost more than half of its value over the past eight weeks, thanks to FDA concerns that the type 2 treatment may be connected with the deaths from acute pancreatitis of six Byetta users. Although the FDA has not proven a direct association between fatal pancreatitis and the use of Byetta, Amylin's stock has fallen nevertheless.
0 comments - Posted Oct 13, 2008
Ben Vereen, the Tony Award-winning, Golden Globe and Emmy Award-nominated actor, was diagnosed with type 2 on Christmas Day last year.
0 comments - Posted Oct 6, 2008
The diagnosis of type 1 diabetes peaks at 13 to 14 years of age, but at any age it immediately requires children and adolescents to learn many complex facets of glycemic self-management. Dr. Elliot Joslin's belief of 85 years ago, that education is not just part of the treatment of diabetes, but rather the treatment itself, still holds true.
1 comment - Posted Oct 6, 2008
I'll never forget the afternoon of January 22, 2003, and the phone call that came from Derek's pediatrician. I was just leaving my classroom that day when I noticed the light on my phone lit up, alerting me to a new voicemail. My heart stopped when I listened to the message. The doctor asked me to call him back as soon as possible.
2 comments - Posted Oct 6, 2008
I awake at 1:00 am with a feeling of sickness in my stomach. I wonder if it's from anxiety created by a weird dream, hormonal imbalances, and/or high blood sugar. Or did I go to bed angry? The deep-sunken feeling of thick stagnant sludge in my stomach begins to settle into my consciousness. My Mini Mag flashlight illuminates the blood sugar meter, which reads 357. I remember in my high blood sugar fogginess that my blood sugar was 140 before I went to sleep, and I did nothing out of the ordinary. Now, only a few hours later, I am rudely awakened and have to force myself to gather my senses to correct the situation. Fluctuations in blood sugar are mind boggling and frustrating, not to mention the feelings of irritability, anger, fatigue, victimization, and depression that come along in daily life with diabetes. It can create a sense of failure if one does not get a handle on creating a healthy mind, body, and spirit.
5 comments - Posted Oct 6, 2008
September 2008
At the recent 44th annual meeting of the European Association for the Study of Diabetes (EASD), sanofi-aventis announced a study demonstrating that a basal-bolus insulin regimen with Lantus® once daily (basal insulin) and rapid-acting Apidra® (insulin glulisine [rDNA origin] injection) at mealtime (bolus insulin) resulted in significant A1c reductions from baseline as compared to pre-mixed insulin in people with type 2 diabetes.
5 comments - Posted Sep 29, 2008
An article published in Diabetologia this month challenges the accepted glucose cut-off values that define hypoglycemia because they have a major effect on reported frequencies of hypoglycemia.
11 comments - Posted Sep 29, 2008
Bret Michaels was only six years old when he was diagnosed with type 1 diabetes. Now 44 years old, he's a twenty-year veteran of the rock and roll scene as the lead singer of the eighties band "Poison."
64 comments - Posted Sep 22, 2008
These days, Doug Burns is a modern Sampson. The reigning Mr. Universe, he’s two hundred pounds of sheer muscle and the picture of good health. Of the skinny little boy with type 1 who used to work out in the woods alone, all that remains are a wry sense of humor and an attractively self-deprecating manner. They’re unexpected in a man who’s triumphed in the uber-masculine world of bodybuilding, but there’s a lot that’s unexpected about Doug Burns.
31 comments - Posted Sep 22, 2008
Many people know that it is beneficial to eat your morning meal, but it can be challenging for many reasons. Breakfast is not the meal to miss, especially when you feel stressed, since it can set the mood for the entire day. The truth is that what you eat for breakfast may be more important than if you eat breakfast at all.
6 comments - Posted Sep 22, 2008
Originally ice cream consisted of milk, cream, sugar, flavoring and lots of air. But modern brands adhering to this original recipe are few and far between.
1 comment - Posted Sep 22, 2008
Gastroparesis doesn't sound good, and it isn't. Literally "stomach paralysis," it is a form of diabetic neuropathy, or nerve damage, that is a common complication of diabetes. The damaged nerve in question is the vagus nerve, named for its vagabond-like wandering nature.
27 comments - Posted Sep 22, 2008
People who tightly control their blood sugar-even if only for the first decade after they are diagnosed-have lower risks of heart attack, death, and other complications ten or more years later, a large follow-up study has found.
0 comments - Posted Sep 18, 2008
Diabetes educator Cindy Young used case studies to illustrate the many little things that can have a big effect on your blood glucose-or just on the readings you get with your meter.
7 comments - Posted Sep 11, 2008
A Canadian clinical study has delivered a double dose of good news for proponents of exenatide (sold commercially as Byetta), a drug used by more than 700,000 Americans to control blood glucose, ease food cravings, and, incidentally, lose weight.
3 comments - Posted Sep 11, 2008
In experiments using blood cells from human patients with diabetes and other autoimmune disorders, Massachusetts General Hospital (MGH) researchers have confirmed the mechanism behind a potential new therapy for type 1 diabetes. A team led by Denise Faustman, MD, PhD, director of the MGH Immunobiology Laboratory, showed that blocking a metabolic pathway regulating the immune system specifically eliminated immune cells that react against a patient's own tissues.
5 comments - Posted Sep 11, 2008
A study sponsored by the Juvenile Diabetes Research Foundation confirms that many older type 1 patients achieve better control of their blood sugar levels by using a continuous glucose monitor (CGM) than by conventional monitoring with a meter and finger pricks.
1 comment - Posted Sep 11, 2008
When I became a type 2 about fifteen years ago, I wanted to find a way to manage my weight and blood sugar with diet and exercise. I tried the high carb diet recommended by my doctor and dietitian for a time. It worked wonderfully well while my blood sugar level was high, but when my blood sugar stabilized and I was able to go off medication, I started gaining weight again. The next thing I tried was low carbohydrate dieting. I found it to be a very effective way to lose weight rapidly, but I was unable to endure the regimen for more than a short time.
5 comments - Posted Sep 11, 2008
By "reprogramming" adult exocrine cells in mice pancreases to function as beta-like insulin producers, Harvard biologists have taken a giant step toward the use of cell regeneration therapy in the treatment of type 1 diabetes.
0 comments - Posted Sep 4, 2008
August 2008
Byetta has had a tough past few days. A lawsuit by a Virginia man alleges that the drug caused his life-threatening bout of severe pancreatitis, and there are rumblings from the U.S. Food and Drug Administration that it may force Byetta's makers to attach a "black box" warning to its container and packaging-a stern, highlighted caution about potentially dangerous, even fatal, side effects.
19 comments - Posted Aug 28, 2008
Imagine someone pressing a pillow over your face while you sleep. You wake up and struggle for air. After 10 seconds, you're allowed to breathe again. But pretty soon, the pillow goes back over your face.
2 comments - Posted Aug 28, 2008
My husband and I have nine children. Elliott is our oldest and when he was diagnosed with type 1 at age 11 in 1996, we were blindsided. Neither my husband, nor I, nor anyone in our extended family had diabetes. Elliot had all of the classic symptoms: excessive thirst, frequent urination, uncontrollable hunger, occasional blurry vision, and (something I think a lot of parents don't recognize as a sign) bedwetting.
11 comments - Posted Aug 28, 2008
The exhibit hall at this year's Children with Diabetes conference in Orlando, Florida, from July 23 to 27, 2008, featured expensive and elaborate booths from well-known companies like LifeScan and large organizations such as the American Diabetes Association. But another kind of company also welcomed people to their booths. They were the diabetes start-ups, companies that were started more often than not because of an intimate connection to the world of diabetes. I spoke to representatives of five of these companies about their products, their mission, and their inspiration.
3 comments - Posted Aug 28, 2008
Babies delivered by Caesarean section have a 20 percent higher risk than normal deliveries of developing type 1 diabetes in childhood, according to a study by a team of researchers from Queen's University Belfast
0 comments - Posted Aug 28, 2008
The members of the AADE are an impassioned group who genuinely want to make a difference in their patients' lives. It was an ideal place for me to be, especially because I had a concern of my own: Why am I getting red dots every time I inject? Every educator I asked went right to work examining the problem and investigating my behavior, truly wanting to help. Unfortunately, they are dwindling in number each year, while patients are increasing in number, making their work ever more demanding.
4 comments - Posted Aug 20, 2008
Diabetes educator Mary M. Austin reported that many people are paying for blood glucose test strips even though their insurance plans would cover them. "There is a lot of misunderstanding," she said. For example, a client of Austin's got a free meter at a health fair. He then paid for strips on his own for six months, until he found out that his insurance plan would cover them if he got a prescription for the strips from his healthcare provider.
3 comments - Posted Aug 20, 2008
Researchers Adeola Akindana and Laura Want explained that diabetes education may be an integral part of a clinical study, as it was in the Diabetes Control and Complications Trial (DCCT) and the Diabetes Prevention Program (DPP). But most diabetes studies have an education component even when it isn't specified in the study's protocol. For example, in a drug study in which participants must check their blood glucose levels, they may need to be taught the correct technique.
0 comments - Posted Aug 20, 2008
You know how important it is to control the sugar and carbohydrates in your diet. So you read food labels and listen to your body cues to make sure you’re getting what you need to stay healthy.
52 comments - Posted Aug 20, 2008
Results from a Harris survey commissioned by the American Association of Diabetes Educators (AADE) show that people with diabetes who must take insulin often struggle with dread and negative impacts on their lives because of it. But more than half of them—52 percent—are reluctant to share their concerns with their healthcare providers.
10 comments - Posted Aug 14, 2008
Do you want to lose weight and improve your blood glucose levels? Do you want to do it without having to weigh your portions and count your calories? Try a low-fat vegan diet. A vegan diet is one with no animal products: no fish, no eggs, no dairy, and, of course, no meat.
22 comments - Posted Aug 14, 2008
Several months ago researchers suspended work on the landmark ACCORD (Action to Control Cardiovascular Risk in Diabetes) study, which tracked 10,251 type 2s, some of them undergoing very tight control of their blood sugar levels.
0 comments - Posted Aug 14, 2008
At the beginning of 2007, we began studying guidebooks and making reservations for a long-anticipated trip to New Zealand and Australia. With limited funds and so much we wanted to do, we decided our budget would go farther if we stayed at hostels. At the same time, we were concerned about Al’s rising blood sugar scores. After visiting relatives during Christmas and celebrating the New Year, Al’s morning scores were as high as 154 mg/dl.
3 comments - Posted Aug 14, 2008
A study of beta cells at McGill University Health Centre in Montreal could hold significant promise for people with type 1 diabetes.
0 comments - Posted Aug 5, 2008
If your summer travels take you south of the border into Mexico, pharmacists say you should avoid the temptation of saving a few dollars by purchasing your medications at farmacias, which sell versions of American prescription drugs made in Mexico.
4 comments - Posted Aug 5, 2008
Type 2s who tried out either of two different basal-bolus treatments using Lantus and Apidra enjoyed significant reductions in post-meal BG levels and longer-term A1c’s.
4 comments - Posted Aug 5, 2008
When the National Federation of the Blind (NFB) hosted its convention June 30 through July 5 in Dallas, Texas, it awarded the Access Plus (A+) Award to Diagnostic Devices, Inc., makers of Prodigy® blood glucose monitoring systems. “The A+ Award program was designed to reward companies that make consumer products that are truly accessible for blind people,” said Eileen Rivera Ley, Director of Diabetes Initiatives for the NFB. The A+ Award is for products that afford the blind the same convenience and features available to everyone else and is awarded only to products and services that meet the highest standards of accessibility.
0 comments - Posted Aug 5, 2008
July 2008
In a report published in the December 23, 2000, issue of the British Medical Journal (BMJ), researchers at the University of Liverpool in the United Kingdom write that hypoglycemia is one of the complications of diabetes most feared by patients. They point out, "Intensive research has been devoted to the development of hypoglycemia alarms."
13 comments - Posted Jul 31, 2008
You’ve got type 2 diabetes. A few years ago, you started using a long-acting insulin once a day, and your fasting glucose levels and your A1c came down. But now your A1c is creeping back up. Your doctor tells you that you need to add a mealtime insulin to your plan.
2 comments - Posted Jul 31, 2008
July 27, 2008 marked the eighth full month that my son has not used insulin. His last A1c was 5.9%, on July 9, 2008. On August 14th of this year, it will be one year since he was originally diagnosed with type 1. As you know, he was taken off insulin on November 27, 2007, about a month after getting the experimental drug teplizumab. I don't know if it is the drug or not, but others have taken it with good results. It will be interesting to see if they ever get the drug approved and can use it quickly on newly diagnosed type 1s.
15 comments - Posted Jul 31, 2008
San Diego-based Amylin Pharmaceuticals, Inc., posted a second-quarter loss of $64.8 million, or 47 cents per share. This compares to a 2007 second-quarter loss of 45 million, or 34 cents a share.
1 comment - Posted Jul 31, 2008
If you are a New Yorker and have been denied CGMS coverage by insurance or would like coverage for a continuous glucose monitoring system, Gina Capone, founder of Diabetes TalkFest, wants you to Raise your Voice.
3 comments - Posted Jul 25, 2008
The provincial government of Ontario has announced it will spend $741 million over the next four years to combat diabetes, including paying the costs of insulin pumps for adults with type 1 diabetes.
5 comments - Posted Jul 25, 2008
A new Spanish language consumer guide to type 2 diabetes, called “Pastillas para la diabetes tipo 2,” has been released by the Agency for Healthcare Research and Quality (AHRQ). The guide provides information on how to control type 2 and includes comparisons of oral medications. AHRQ data show that nearly one in eight Hispanics takes a prescription drug for diabetes.
0 comments - Posted Jul 25, 2008
You might think that having a disease is the last thing you would want broadcast over the World Wide Web. But for some writers, getting the word out there is the main idea. In a world inundated with celebrity gossip and angst-ridden posts, a few people rise above the online mess and use their blogs to foster a sense of community in what could otherwise be an isolating dilemma: living with diabetes.
10 comments - Posted Jul 25, 2008
Before diabetes, I was a normal teenager whose greatest worry was whether I’d get an A or a B on a test. I was strong and healthy. Somehow, I took for granted all the freedoms that diabetes took away from me. Last year, at the age of fifteen, I learned that every day, even every breath, that we are given is a true gift.
4 comments - Posted Jul 25, 2008
Although trans fats are the new bad boys of the nutritional and cardiovascular worlds, they don’t seem to have any effect on insulin resistance in lab rats.
1 comment - Posted Jul 17, 2008
Until recently, scientists believed that the processes leading to beta cell death in people with type 1 and type 2 diabetes were similar. But a recent study from the Garvan Institute of Medical Research in Sydney, Australia, indicates that the cause of cell death in type 2s involves a form of cellular-level stress not found in type 1s.
1 comment - Posted Jul 17, 2008
The National Institutes of Health will fund studies at 11 research centers in the United States, Canada, Sweden and Norway to look into ways to improve outcomes and lessen the side effects from islet cell transplantations in people with type 1 diabetes.
1 comment - Posted Jul 17, 2008
Have you heard the story of the little boy who was on the beach after a storm? Thousands of starfish had washed ashore, and he picked up one after another and threw them back into the sea. A man watched him work and after some time said to the boy, “Look at all these starfish. You’re never going to be able to save them all. Do you think all your work will make a difference?” The boy thought for a minute as he looked up and down the beach. “I don’t know,” he said as he picked up another starfish and flung it into the brine, “but it sure will make a difference to this one!”
4 comments - Posted Jul 10, 2008
Metformin, combined with dietary changes and exercise, seems to help obese pre-diabetic adolescents, especially girls, lose weight, says a report in the June 2008 Journal of Pediatrics.
8 comments - Posted Jul 10, 2008
Elevated levels of fetuin-A, a protein produced by the liver that inhibits the action of insulin, may be a way to identify older people who are at risk of developing type 2 diabetes, say researchers at the University of California at San Diego.
0 comments - Posted Jul 10, 2008
This article was submitted by Dr. Richard Cassidy and was not written by Diabetes Health.
0 comments - Posted Jul 10, 2008
A University of Texas professor of medicine says that diabetes doctors should take “a leap of faith” and begin administering newly-diagnosed people with diabetes a “triple treatment” consisting of the drugs metformin, pioglitazone and exenatide.
4 comments - Posted Jul 10, 2008
In the wake of its clearance by the FDA, Animas Corporation says it will make its new OneTouch® Ping™ glucose management system available to people with diabetes by mid-August.
3 comments - Posted Jul 10, 2008
The non-profit Institute for Safe Medication Practices says there has been an increase in reports about mix-ups between prescriptions of insulin U-100 and insulin U-500 (U-500 is a concentrated insulin that is five times stronger than U-100).
0 comments - Posted Jul 3, 2008
Yes, they lacked indoor plumbing, permanent settlements and elevated manners when it came to eating, but our hunter-gatherer ancestors may have eaten a diet that can help modern people combat metabolic syndrome and even type 2 diabetes.
7 comments - Posted Jul 3, 2008
The Food and Drug Administration is considering a requirement that before receiving agency approval, new diabetes treatment drugs must not only lower blood sugar levels, but also demonstrate a positive effect on heart disease and lifespan.
1 comment - Posted Jul 3, 2008
Molecular malfunction may explain the development of high blood pressure, diabetes and immune problems, says a new research report.
9 comments - Posted Jul 3, 2008
I’ve always been a pretty good traveler. I simply checked the weather at my destination and packed accordingly. Easy. Then I learned that I had diabetes, and suddenly even weekend trips required an intense amount of additional preparation.
2 comments - Posted Jul 3, 2008
The Diabetes Center at the University of California at San Francisco is currently seeking to enroll patients in five studies of people with type 1 and type 2 diabetes, and three related studies of non-diabetics:
1 comment - Posted Jul 3, 2008
June 2008
Every pilot’s nightmare is the thought of losing his medical certification and being stopped from flying. That happened to me in May of 1986, when I was diagnosed with type 1. In accordance with the International Civil Aviation Organization (ICAO) Standards and Recommended Practices, Canada, along with every other country in the world, would not allow insulin-dependent pilots to hold any type of pilot’s license. My short eight-year career with Air Canada came to an abrupt end, and I was told in no uncertain terms that I would never be allowed to fly an aircraft again.
9 comments - Posted Jun 26, 2008
Years ago, John Bantle, MD, gave brownies to people with diabetes. Brownies made with real sugar. And their blood glucose levels…did not skyrocket.
27 comments - Posted Jun 26, 2008
Dear Editor:
A few weeks ago, I was reading in bed at around one o’clock in the morning. I got up to administer my twice-daily Lantus dose and a small amount of Humalog to "cover" the carbs I'd consumed about an hour earlier.
1 comment - Posted Jun 26, 2008
This year Carb Cards™ have added calorie and fat gram information to the 3rd edition of the carbohydrate counting flashcards. Twelve new cards with information on such foods as oatmeal, beans, and fish have been added to the revised 55-card deck to encourage healthier choices and more variety in meal planning.
1 comment - Posted Jun 26, 2008
Twenty-four diabetes doctors and researchers from the United States, Canada, the United Kingdom, Finland, Sweden and Portugal have published a study criticizing the American Diabetes Association (ADA) assertion that diabetics should consume no fewer than 130 mg of carbohydrates daily and the European Association for the Study of Diabetes (EASD) statement that low-carb diets are “not justified.”
28 comments - Posted Jun 26, 2008
Tekturna Reduces Kidney Disease Indicator
The blood pressure medicine Tekturna (aliskiren) may have a beneficial side effect for people with type 2 diabetes and high blood pressure who are at risk of kidney disease. According to a recent article in The New England Journal of Medicine, the drug reduces proteinuria, a key indicator of kidney disease, by 20 percent in patients with type 2 diabetes.
2 comments - Posted Jun 26, 2008
Clinical trials have been a staple of diabetes research ever since 1922, when doctors in a Toronto hospital injected a young boy dying from the disease with pancreatic extracts. (The extracts contained the recently discovered hormone, insulin. The boy survived and lived another 13 years.)
3 comments - Posted Jun 19, 2008
Drug manufacturer Novo Nordisk has applied to the U.S. Federal Drug Administration and the European Medicines Agency for approval of liraglutide, a human GLP-1 analog* that is taken once daily for the treatment of type 2 diabetes.
0 comments - Posted Jun 19, 2008
Canadian researchers report that succinobucol, an anti-oxidant drug used to treat cardiovascular inflammation, appears to have a beneficial effect in lowering the risk of developing diabetes. Even patients who already have diabetes, they say, achieve better blood sugar control while on the drug.
1 comment - Posted Jun 19, 2008
Diabetes treatments are now the leading driver of prescription drug spending growth, displacing lipid-lowering drugs, which tumbled in price after a reign of 10 years in the top position. Generic drugs are cutting the cost of treating high cholesterol.
2 comments - Posted Jun 12, 2008
Dear Editor,
Sometimes the personal challenges we confront lead us to recognize value and opportunities we had not discovered before. That has been my recent experience, and that’s why I am especially proud to be a member of the Phoenix legal community.
3 comments - Posted Jun 12, 2008
Dear Diabetes Health,
After reading the story in the April/May Diabetes Health about the mother and daughter who won approval from Blue Cross/Blue Shield to pay for the continuous monitor, I wanted to share our story.
5 comments - Posted Jun 12, 2008
”Intense Hydrating Cream” from Pedi-Relax®, a cream made in France and used by people with diabetes in Europe to treat their soles, is now available in the United States at www.cvs.com for $7.99. The line is specifically formulated for extremely dry and damaged feet and is endorsed by the Federation of International Podiatrists.
1 comment - Posted Jun 12, 2008
People in the diabetes community, desperate for a cure, sometimes express considerable paranoia about the goals of the pharmaceutical industry.
15 comments - Posted Jun 11, 2008
Dear friends of Diabetes Health,
We value your hard-earned diabetes wisdom and we want you to share it with the world! Please join us as a professional or lay diabetes advisor in one of our Diabetes Health website content Rooms.
3 comments - Posted Jun 6, 2008
In the 17 years I have known Robert Oringer, I can honestly say that he has a soaring entrepreneurial spirit and a fierce independence – he is a man who is hard to harness. His mind is always ticking, excited by the next innovative idea.
2 comments - Posted Jun 2, 2008
May 2008
The desire to be thin can be overwhelming. Few people know that better than Kelie Gardner, who started inexplicably losing a lot of weight during high school. She thought it was great until she discovered the reason—she has type 1 diabetes and her body can’t absorb the nutrients it should. After she was diagnosed and started taking insulin, Gardner returned to a healthy weight. Unfortunately, she wasn’t happy with this sign of improvement. “When I was on insulin, my body was able to start functioning normally,” says Gardner, now 26. “I went up to a normal body weight, but I was used to being skinny. I had the fear of, ‘Oh gosh, I’m going to be fat.’”
21 comments - Posted May 30, 2008
With annual worldwide sales topping 1.3 billion dollars, insulin pumps are one of the most popular devices in the treatment of diabetes. Not only do they allow people with type 1 diabetes to more easily manage their blood glucose levels, but they also help users regain their freedom and enjoy a more normal life.
14 comments - Posted May 30, 2008
Our Advisory Board Member Dr. Richard K. Bernstein has courageously championed the low carb diet for 20 years despite the fact that many people thought he was “out to lunch.” Although his patients loved him for helping them control their high BGs and reverse their complications, other medical professionals often criticized his low carb methods.
9 comments - Posted May 30, 2008
While none of us would have asked for diabetes, and it's a semi-regular (OK, almost constant) pain in the butt, and I go from highs to lows both in my blood sugar and my frustration level, I still try to remain focused on my blessings: the good in my life and what diabetes gives me.
1 comment - Posted May 30, 2008
Dear Diabetes Health,
I appreciated Jamie Bailes’ (April/May 2008) article on helping overweight kids. To me, it illustrated the complexity of weight regulation and the folly of linking it to one factor (fat).
2 comments - Posted May 30, 2008
Researchers at Children’s Hospital in Pittsburgh have started an FDA-approved phase 1 test in humans of a lab procedure that successfully reversed type 1 diabetes in mice.
8 comments - Posted May 30, 2008
HealthDay reports that according to a University of Miami study, people with type 1 diabetes who received transplanted islet cells from human donors lived insulin-free for up to two years.
1 comment - Posted May 30, 2008
Is it possible that a dip in the hot tub can cause a dip in the blood sugars? According to a pilot study that appeared in the September 16 issue of The New England Journal of Medicine (NEJM), "hot tub therapy" helped a group of type 2s reduce their blood sugars, lose weight and improve sleep patterns.
11 comments - Posted May 23, 2008
In the current era of “zero tolerance,” public school students who have diabetes have been caught in a frustrating crossfire.
13 comments - Posted May 22, 2008
Editor's Note: This week's letter is from Joan Hoover, one of our favorite and most outspoken board members. Joan is also our patient advocate advisor. She is a tireless diabetes educator and advocate for people's access to clear, accurate, and unbiased information about the disease. When Joan speaks, we sit up and listen! Her letter is addressed to Editor-in-Chief Scott King and Diabetes Health pharmacy advisory board member R. Keith Campbell. Campbell had commented favorably on news that a doctor had successfully treated obesity in children by prescribing amphetamines.
7 comments - Posted May 22, 2008
Dear Editor, I am a medical student in the M.D. program at Oregon Health and Sciences University and a type 1 diabetic of almost 10 years. I use a Medtronic pump and I also use their continuous glucose monitoring system (Paradigm Real-Time).
34 comments - Posted May 22, 2008
It has long been known that type 2 diabetes is linked to obesity, particularly fat inside the belly. Now, researchers at the Joslin Diabetes Center have found that fat from other areas of the body can actually reduce insulin resistance and improve insulin sensitivity.
0 comments - Posted May 22, 2008
Nassau University Medical Center said it had underestimated the number of diabetes patients potentially exposed to reused insulin pens and would be sending letters to at least 840 of them, instead of 185, urging them to be tested for hepatitis C and B and HIV.
3 comments - Posted May 22, 2008
Let me start with my maternal grandmother, Helen. Helen had diabetes and lived to the age of 73. We all assumed that she didn’t do a good job with it, as we would often find candy wrappers under her bed. When it came to taking care of herself, Helen was my mother’s role model.
5 comments - Posted May 15, 2008
According to the American Dental Association (ADA), people with diabetes are more prone to periodontitis, tooth decay, oral fungal infections, taste diminishment, gingivitis and delayed healing time than people without the disease.
7 comments - Posted May 15, 2008
Glucose-controlling metformin, the generic drug that is the first medication for many newly diagnosed type 2s, could soon be available in a chewing gum.
4 comments - Posted May 15, 2008
Scientists have long considered type 1 diabetes to be an autoimmune disease in which the body mistakenly attacks a part of itself–in this case, the insulin-producing structures of the pancreas called the islets of Langerhans.
1 comment - Posted May 15, 2008
Newswise — “The American Association of Clinical Endocrinologists applauds the FDA’s efforts to protect the safety of children and adolescents who are using insulin pumps,” said Dr. Richard Hellman, the Association’s President.
1 comment - Posted May 15, 2008
You can't have diabetes without knowing about the merits of exercise.
1 comment - Posted May 8, 2008
"Insulin Quiz: Are You Smarter Than a Doctor" (April-May '08, pp 12-15) was an excellent article, if perhaps a little frightening. I couldn't help but wonder how well the parents of diabetic children would do on the quiz, and where they might have learned their lessons.
6 comments - Posted May 8, 2008
Our regular columnist, Mr. Metabolism, addresses the current issue regarding cow's milk and its possible link to diabetes.
2 comments - Posted May 8, 2008
The Diabetes Exercise and Sports Association Conference will feature speakers from the sports and health care professions, the latest research on diabetes, a discussion on the role of exercise in insulin pump therapy, and advances in diabetes treatment and management.
0 comments - Posted May 8, 2008
BOZEMAN, Mont. (April 30, 2008) – Governor Brian Schweitzer appeared at Montana State University Tuesday to celebrate Montana’s scientific contribution to the development of barley varieties that serve as a natural way to help manage diabetes, heart disease and obesity.
3 comments - Posted May 8, 2008
I was diagnosed with type I insulin-dependent diabetes 54 years ago at the age of 22 months. A dear family friend suggested my parents take me to our family doctor and have me checked for diabetes after I showed some of the more common symptoms. I was unusually cranky and always hungry, but had a stomach that was hard to the touch as though food was not digesting properly. I was also always thirsty, drinking a lot and urinating frequently. Our doctor tested my blood sugar, and the result was high enough to indicate diabetes. He put me on 60 units of insulin per day and told my parents to take me to the hospital 30 miles from the little Western Kansas town where we lived to get a shot of insulin once a day.
17 comments - Posted May 8, 2008
Most people are aware of the health hazards that come with sugar consumption. Still, sugar restriction is difficult for our generation, which has developed a strong sweet tooth. However, for those who want to or must limit sugar, there is an extensive variety of sugar substitutes on the market.
21 comments - Posted May 1, 2008
A word of caution about the values used below. This study was conducted using people without diabetes. Some people with diabetes experience symptoms at higher glucose levels than the study suggests. Other people with diabetes appear to function well with blood sugars in the 30's and 40's (mg/dl). Therefore, the values in the study should only be used as an approximation. This study also used plasma glucose levels. Your values done at home might be 20 percent lower or higher than these lab values. For example, epinephrine release in someone without diabetes would begin at about 63mg/dl with a home blood glucose meter.
43 comments - Posted May 1, 2008
April 2008
Hi, Keith,
One of our most popular articles right now is about the many, many folks who accidentally mix up their insulin bottles and take a huge dose of fast-acting insulin by mistake, thinking they are taking long-acting. (See the article and the 22 reader comments here.)
10 comments - Posted Apr 28, 2008
Have you ever met anyone who thinks they get enough exercise? Everywhere you look there are books, web sites, exercise videos and articles telling people how to get started and how to stay motivated. Our family certainly avoided any kind of exercise plan. Although we played in the yard, took walks, rode our bikes, and played soccer, I never woke up thinking, "What can we do for exercise today?" Even though I knew we weren't active enough, I didn't want another thing to do.
0 comments - Posted Apr 28, 2008
The FDA has cleared the OneTouch UltraLink wireless meter as the only meter certified by Medtronic to wirelessly communicate with its diabetes management products in the United States. The meter uses Medtronic-certified wireless technology to transmit glucose readings directly to MiniMed Paradigm insulin pumps and the Guardian® REAL-Time continuous glucose monitoring system. This makes bolus dosing more accurate and easier for patients compared to the manual entry of blood glucose readings.
8 comments - Posted Apr 28, 2008
Does anyone living in our well-nourished country, eating a reasonable diet, really need to take vitamins, minerals, or herbs? Should a person with diabetes take them? If so, which ones and how much? When it comes to supplements, the answers are often unclear.
20 comments - Posted Apr 23, 2008
A Question-and-Answer Session With Jordan Hoese, A 14-Year-Old Type 1 Marathon Runner.
16 comments - Posted Apr 21, 2008
I was working at my computer when my 37-year-old daughter, Laura, walked into my home office and burst into body-wrenching sobs. She finally managed to blurt out that a doctor had just told her that my 7-year-old grandson had juvenile diabetes and needed to go straight to the hospital. I didn't want to add my own upset to the chaos of the day, so I went through the motions, calming Laura and being as helpful as I could. My husband Jack, a psychiatrist, canceled his patients and picked up Danny and his ten-year-old sister Jessica at school. The five of us met Laura's husband Brian at the hospital and spent two days learning as much as we could about Danny's diabetes.
5 comments - Posted Apr 21, 2008
We’d like to invite diabetes professionals, persons with diabetes (and the people who love and help them) to contribute articles to Diabetes Health.
0 comments - Posted Apr 21, 2008
This is a thank-you note for the article, “An Appeal to Insulin Manufacturers,” on page 27 of Diabetes Health (Feb/March 2008). In the 10 years that I have been using insulin, I have made the “near fatal” mistake twice. I use Lantus and Apridra (5 units of Apidra before breakfast and lunch, and 8 units before dinner; 50 units of Lantus at bedtime). I realized what I had done after the fact and stayed up all night eating and monitoring. I was so scared each time I ate my blood sugar up to 300 mg/dl and 400 mg/dl!
1 comment - Posted Apr 21, 2008
In wake of news that its inhaled insulin product Exubera has been linked to lung cancer, Pfizer Inc. has announced that it will cease manufacturing the drug and update labels on the remaining product to carry a cancer warning.
6 comments - Posted Apr 17, 2008
Tim’s Parker’s 15 minutes of fame – at least in the diabetes community – began in March when he learned that he had been the purchaser of Medtronic’s one millionth continuous glucose monitoring sensor.
1 comment - Posted Apr 16, 2008
It is estimated that nearly 3 million African-Americans have diabetes – 17 percent of all diabetes patients in the United States. That figure is growing as the proportion of African-American patients diagnosed with diabetes consistently increases year to year, according to research from GfK Market Measures’ Roper Global Diabetes Group.
0 comments - Posted Apr 16, 2008
Forty-six years of coping with IDDM hasn’t stopped me! I’m a published, award-winning poet, an actress and, in my “retirement,” a vocalist. All this from a girl from a far off place known as The Bronx – and a policeman’s daughter, no less!
0 comments - Posted Apr 16, 2008
LifeScan, a Johnson & Johnson company that manufactures OneTouch blood glucose meters, is sponsoring an online sweepstakes for children with diabetes that will offer the opportunity to attend a diabetes camp for free this summer.
2 comments - Posted Apr 16, 2008
It’s late October, 2007, and Prof. Wendy Coleman has just learned about a competition called the Bayer Dream Fund. Coleman, a type 2 who was diagnosed in 2005, has been told that the fund grants a large cash award to the competition winner – money the winner can use to fund a personal project designed to spread the word about managing and living successfully with diabetes.
4 comments - Posted Apr 10, 2008
Years from now, when we’re looking for significant milestones in the struggle to get insurers to cover the cost of continuous glucose monitors, keep this one in mind: Medtronic has just announced the sale of its one millionth sensor from its line of CGM products.
7 comments - Posted Apr 10, 2008
Hi, Mr. King: Thanks so much for Diabetes Health. Being a type 1 diabetic, I have benefited from many of its articles. I would like to tell you a story concerning my daughter, Morgan, and say what an inspiration Nick Jonas from the Jonas Brothers is. Morgan is 12-½ years old and a huge Jonas Brothers fan! Of course she and her friends wanted tickets for the Louisville Palace show in February. A few of her friends’ mothers went and stood in line on the cold morning that the lottery tickets went on sale.
53 comments - Posted Apr 10, 2008
Editor: I’m writing in regard to an article in Diabetes Health (Feb/March 2008) on page 27 about help in avoiding near-fatal mistakes taking insulin. To read the original article, go here.
9 comments - Posted Apr 9, 2008
On April 25-27, 14 families of children with diabetes will enjoy a weekend at the Double H Ranch in Lake Luzerne, N.Y., thanks to Pump Wear Inc., which manufactures insulin pump-related accessories.
2 comments - Posted Apr 9, 2008
Since its introduction in 2005, Byetta has become “the talk of the town” as one of the most powerful, yet benign, diabetes drugs of the 21st century.
4 comments - Posted Apr 2, 2008
When Dee Brehm was diagnosed in 1949 with type 1 diabetes, her prospects were not bright: a permanent chronic condition, a reduced life span, potentially devastating complications and perhaps no children. She married Bill Brehm in 1952, and they began a partnership knowing that together they would have to manage her disease. Dee subsequently defied the dim outlook for her life: She has two children and six grandchildren, and she has surpassed the half-century mark with this disease having been spared the ordeal of complications.
23 comments - Posted Apr 2, 2008
March 2008
Professional surfer Scott Dunton, 21, has two missions in life: To keep climbing in the rankings as one of the world’s top competitive surfers, and to spread the word to children and teenagers everywhere that having diabetes doesn’t mean life’s joys come to a halt.
16 comments - Posted Mar 27, 2008
People who live with diabetes on a daily basis are usually instructed to eat right, maintain regular physical activity, and if necessary, take medication. What many may not know is that these medications that help control healthy insulin levels may lead to unexpected events at the dentist’s office. According to a study in the November/December 2007 issue of General Dentistry, the clinical, peer-reviewed journal of the Academy of General Dentistry, diabetic patients especially need to communicate special needs to their dentists. This is because of harmful interactions that could occur with materials and medications used at dental appointments.
5 comments - Posted Mar 27, 2008
What is “surprising” about the partial halting of the ACCORD study (“Diabetes Study Partially Halted After Deaths,” Feb. 7, 2008) is that the researchers were so surprised by completely predictable results.
13 comments - Posted Mar 27, 2008
Editor:
My son was diagnosed in August 2007 with juvenile diabetes. I am a registered nurse and was devastated by the diagnosis because I was just completely paralyzed by the fear of potential complications. It was also a tremendous shock to be on the other side of health care – receiving information from hurried staff, including doctors, glancing at their watches while I asked one too many questions.
28 comments - Posted Mar 21, 2008
Scientists at Massachusetts General Hospital (MGH) in Boston have initiated a phase 1 clinical trial to reverse type 1 diabetes. The trial is exploring whether the promising results from the laboratory of Denise Faustman, MD, PhD, can be applied in human diabetes.
13 comments - Posted Mar 19, 2008
I am a diabetic and was taking four insulin shots per day and still had problems with my sugar. I did two months of research on the Web because I had to find a way to get off the shots. I hate needles I was astonished at what I found on natural herbs!
37 comments - Posted Mar 19, 2008
Five weeks ago I hurt my ankle. Really hurt it. I either tore a tendon or a ligament or had a severe stress fracture or something. Although I’ve been to my podiatrist twice now, the diagnosis is still unclear. The X-ray showed no break, and while the doc didn’t feel I needed an MRI, I figured that if my insurance paid for it, I did. I want to know we’re doing everything possible to get this fixed as quickly as possible (which already seems impossible after five weeks), because not walking is having several unpleasant effects on me:
3 comments - Posted Mar 19, 2008
The table was set for Thanksgiving and all the family was there. Joey, the baby, was the center of attention. This would be the second Thanksgiving he had witnessed in his relatively short life. Somebody remarked that he looked thin, but Sandra, Joey's mother, thought that it was just a sign of growth. As the turkey and mashed potatoes were served, the family turned its attention away from the cooing baby to ladling piles of food onto plates. Joey didn't eat much that night, but kept asking for more to drink.
20 comments - Posted Mar 13, 2008
Perhaps more than anyone, people with diabetes know that the motto “Just say no” often doesn’t work.
28 comments - Posted Mar 13, 2008
Blood sugar control is the heart and soul of diabetes management. How you handle it determines what will be the consequences of your diabetes.
2 comments - Posted Mar 13, 2008
It's not easy to do, but regular exercise is a wonderfully effective way to control your blood sugar and fend off the other metabolic effects of diabetes.
4 comments - Posted Mar 13, 2008
NEW YORK – Growing evidence shows that surgery may effectively cure type 2 diabetes – an approach that not only may change the way the disease is treated, but that introduces a new way of thinking about diabetes.
18 comments - Posted Mar 13, 2008
For people with diabetes, healthcare is just plain more involved. Hospitalizations require extra work because you must control your diabetes during your stay, and insurance can be problematic because insurers are often unwilling to pay for what you need.
0 comments - Posted Mar 9, 2008
Continually revved up insulin production, the kind that results from overeating and obesity, slowly dulls the body’s response to insulin. As a result, blood sugar levels start to creep up, setting the stage for diabetes-associated complications such as blindness, stroke and renal failure. To make matters even worse, chronically elevated blood sugar concentrations exacerbate insulin resistance.
1 comment - Posted Mar 6, 2008
Don’t make a run on the tea section of your neighborhood supermarket just yet, but keep this in mind: Scientists at the Neurosciences Institute of the University of Dundee in Scotland say that drinking black tea could help combat diabetes.
0 comments - Posted Mar 6, 2008
February 2008
About 10 years ago Diabetes Health began reporting on "omission," the practice among some type 1 teen girls of deliberately stopping their insulin intake to produce drastic - and fast - weight loss.
1 comment - Posted Feb 29, 2008
Eli Lilly and Company has introduced KwikPen, a pre-filled insulin pen containing its Humalog insulin brand of insulins. The pen is the third that Lilly has introduced over the past 12 months, following in the wake of the HumaPen MEMOIR, a digital insulin pen with memory, and the HumaPen® LUXURA HD, a reusable pen for people who need insulin dosing in smaller increments.
9 comments - Posted Feb 28, 2008
A Wayne State University Health Clinic study has shown that a single pill containing both a blood pressure-lowering drug and a cholesterol-lowering drug may be of particular benefit for African Americans.
0 comments - Posted Feb 20, 2008
A Texas endocrinologist who recently put the recently FDA-approved Medtronic iPro continuous glucose recorder through its paces with diabetic patients calls the tool a major step forward in doctors' ability to accurately monitor the disease.
10 comments - Posted Feb 18, 2008
"Constant Vigilance!" roars Mad Eye Moody, Harry Potter's Defense Against the Darks Arts teacher. "You need preparing. You need arming. But most of all, you need to practice constant, never-ceasing vigilance. Get out your quills…copy this down…"
0 comments - Posted Feb 14, 2008
To successfully treat diabetes, you must take charge of your own diabetes management. You need to know your medications, and you need to know your pharmacist. But that kind of intimate knowledge has become a lot more complex in the past decade.
3 comments - Posted Feb 12, 2008
Blondie Fram has been living well with type 2 diabetes for at least four decades, and probably many more before she was diagnosed. She attributes her long life with diabetes first and foremost to solid family ties. "I have had wonderful support from my children and their spouses," she says.
1 comment - Posted Feb 10, 2008
City of Hope researchers were among the more than 50 international investigators reporting advances against type 1 diabetes at the recent Rachmiel Levine Diabetes and Obesity Symposium in Newport Beach, Calif.
4 comments - Posted Feb 9, 2008
After seeing an increase in deaths among type 2 participants, the National Heart Lung and Blood Institute (NHLBI) has halted the intense blood sugar control portion of its years-long study on controlling cardiovascular risks to people with diabetes.
14 comments - Posted Feb 8, 2008
Pioneering low-carb diet advocate Dr. Richard K. Bernstein has responded to the American Diabetes Association's recent support for low-carb diets with a critique of several of the ADA's most cherished notions.
30 comments - Posted Feb 8, 2008
I have been using insulin for over 29 years, and during this time I have experienced too many lows to recall. My endocrinologist informed me that insulin users who have an A1c less than 7 percent typically require emergency assistance for hypoglycemia about every six to nine months.
26 comments - Posted Feb 7, 2008
Recently, meal-replacement bars, powders and beverages have been touted as a popular way of providing nutritious options for today's busy lifestyles, as well as aids for weight loss and poor appetite.
0 comments - Posted Feb 5, 2008
A Canadian study asserts that girls and young women with big breasts run a 68-percent greater chance of acquiring diabetes by middle age than their smaller-breasted peers.
4 comments - Posted Feb 4, 2008
I don't know if you watched this show that aired the week of January 20 here in Rochester, N.Y., on WXXI Public TV. The program included a short segment where a 12-year-old type 1 diabetic relied upon a medical dog to avoid seizures. It was very incomplete and misleading.
5 comments - Posted Feb 2, 2008
SK: We’re joined on our show by Craig Eberhard, vice president of sales at Amylin Pharmaceuticals. Hey, Craig, thanks for coming on the show. Amylin has one of the most innovative products that I’ve heard of in years. It’s called Byetta.
8 comments - Posted Feb 1, 2008
January 2008
I just had a frightening experience. A severe hypoglycemic, I took my regular 5 units of R Humulin 30 minutes before lunch. Instead of my normal sandwich and milk at lunch, I drank a glass of Slim Fast with milk. I carefully read the label and figured out that it was almost identical to the sandwich in calories, carbs and sugars.
11 comments - Posted Jan 30, 2008
Eight-year-old Olivia Miller asked for a Chihuahua for Christmas, but what she received was far more precious than just any pet. That's because Olivia and her new little dog both have diabetes and today they comfort and encourage each other through the rigors of dealing with the disease.
3 comments - Posted Jan 27, 2008
By mid-2010, an international clinical trial now underway may conclusively confirm insulin's ability to limit damage from heart attacks. The trial, called INTENSIVE, will be conducted at 90 centers in the United States, Canada, Brazil and Argentina.
3 comments - Posted Jan 24, 2008
Sponsor a pig and you can help a unique collaboration between Spring Point Project and the University of Minnesota to begin transplanting insulin-producing islet cells from pigs to humans within the next two years.
10 comments - Posted Jan 24, 2008
Swedish scientists have found that alcohol lowers blood sugar by redirecting blood within the pancreas and sending massive amounts of it to the islets.
16 comments - Posted Jan 23, 2008
Editor: I am an enthusiastic reader of your magazine. I appreciate the number of times you have tackled some of the bigger questions of diabetes management that others have ignored.
31 comments - Posted Jan 23, 2008
"It feels like you accidentally pricked yourself with a pin, only it's not accidental and you have to do it over and over again in the same areas."
34 comments - Posted Jan 18, 2008
To successfully treat any disease, one must know what disease to treat. Treating only a symptom of the disease will leave the underlying disease unchecked and possibly worse. For example, we evolved the "runny" nose to help us clean out upper respiratory infections. So taking a decongestant to eradicate the symptom of a "runny" nose is actually counterproductive for the underlying disease.
23 comments - Posted Jan 13, 2008
Startling statistics are only one reason sufferers should get help and why research into this lethal combination must continue. On the list of deadly diseases in the United States, diabetes ranks fifth. And for so many reasons: major killers like heart attack and stroke are among a slew of diabetes' potentially lethal complications.
15 comments - Posted Jan 12, 2008
My introduction into the world of diabetes occurred long ago, when I was diagnosed with brittle diabetes at the age of six. I spent the majority of my childhood in the hospital. There, my doctors, nurses, and nutritionists taught me how to balance my food intake and insulin injections so that I could lead a somewhat normal life.
0 comments - Posted Jan 11, 2008
The National Athletic Trainers Association has issued a seven-element plan for helping athletes with type 1 diabetes maintain proper blood sugar levels while competing, training or traveling.
2 comments - Posted Jan 10, 2008
The powerful - but cautious - American Diabetes Association has announced that it now supports low-carbohydrate diets for people with diabetes who want to lose weight.
7 comments - Posted Jan 9, 2008
Here's a sour little bit of good news for type 2s: taking two tablespoons of vinegar at bedtime can lower fasting glucose levels the next morning by as much as 6 percent.
19 comments - Posted Jan 8, 2008
As the parents of a very active and accident-prone 13-year-old son, my husband and I have had our share of emergency room visits.
1 comment - Posted Jan 5, 2008
You and everybody else alive encounter stress, daily, hourly and minute by minute. As unavoidable, inscrutable, and sometimes as aggressive as the IRS, stress is part of the human condition. It is not just a sense of being tense but is any event that causes a complex physiologic response called the "stress response."
4 comments - Posted Jan 3, 2008
Because scientists often tend to dismiss what they don't fully understand, many of them used to think that C-peptide had no physiological function. But while it's true that C-peptide does nothing to lower blood sugar, recent research is finding that it might have a role in preventing diabetes complications.
19 comments - Posted Jan 3, 2008
INDIANAPOLIS, July 21 - Eli Lilly and company today announced that it has begun limited testing in healthy human volunteers of biosynthetic human insulin produced by recombinant DNA technology. The company also announced that it has started construction of the world’s first manufacturing facilities—at a cost of $40 million—to employ recombinant DNA technology to produce the biosynthetic human insulin.
1 comment - Posted Jan 1, 2008
December 2007
Awhile back, three macaque monkeys with type 1 diabetes received transplants of 19 pig pancreas primordia, each one smaller than the period at the end of this sentence.
5 comments - Posted Dec 31, 2007
When a woman is pregnant, she needs to produce more insulin than usual because her body is feeding more cells than normal. A hormone, prolactin, which is abundant during pregnancy, causes more pancreatic islet cells to grow in order to produce the extra insulin.
0 comments - Posted Dec 30, 2007
Bayer Diabetes Care has recalled 230,000 bottles of Contour TS test strips after finding that the strips resulted in blood glucose readings 5 to 17 percent higher than actual levels.
0 comments - Posted Dec 29, 2007
Recently on "Good Morning America," a friend of mine (and fellow A1c champion) watched author Gary Taubes talk about his new book, Good Calories, Bad Calories. My friend sent this email around: "Taubes says that exercise makes us hungry for carbohydrates and that carbohydrates cause insulin secretion, which creates fat."
49 comments - Posted Dec 27, 2007
When my son Danny was diagnosed with type 1 diabetes, I was in such a state of shock that I couldn't absorb the two days of education that our hospital provided. My head was reeling.
1 comment - Posted Dec 22, 2007
Researchers have found that fenofibrate, also known as Lofibra and TriCor, reduces the progression of diabetic retinopathy in humans. (Retinopathy occurs when the small blood vessels that supply the eye begin to leak and swell, resulting in progressive vision loss.)
1 comment - Posted Dec 22, 2007
The name insulin comes from the Latin insula, for islands. It refers to the pancreatic islets of Langerhans that contain the beta cells.
1 comment - Posted Dec 20, 2007
"Delight" is a word rarely found in company mission statements, but it's part of Owen Mumford's rather sweet and very British declaration - the company aims to "delight its customers" with its products, keeping in mind that they just might "change the life of our nearest and dearest."
0 comments - Posted Dec 19, 2007
Today, about four percent of Americans bank their children's cord blood just in case it might come in handy, and more are doing it every day. Now a small study announced at the 67th Scientific Sessions of the American Diabetes Association has found that infusions of umbilical cord blood may preserve insulin production.
1 comment - Posted Dec 18, 2007
In healthy people, beta cells are like tiny factories that churn out insulin. Proinsulin, which is the raw material for finished insulin, is produced in the endoplasmic reticulum deep within the beta cells.
0 comments - Posted Dec 18, 2007
Low doses of resveratrol, an ingredient found in red wine, make insulin-resistant mice more sensitive to insulin. Don't try this at home, however, because you'd have to drink almost a gallon of wine every day to get the same effect.
3 comments - Posted Dec 17, 2007
To conclude our pump survey, we asked you how you'd like to see pumping improved. As usual, you came up with a plethora of intriguing suggestions, although some were a bit more visionary than others: One reader said, "I wish someone would invent a device that could be waved over a meal, and it would display the number of carbs in the meal."
43 comments - Posted Dec 14, 2007
I love that old Greek proverb, "There is nothing permanent but change," because it's so perfectly applicable to diabetes. It seems that almost every day now we're finding more causes, more treatments, and, inevitably, more problems with new treatments.
0 comments - Posted Dec 14, 2007
In a recent randomized study, 69 people with type 2 diabetes who were already taking metformin were given either Byetta or Lantus for a full year. When the results were in, Byetta came out ahead on several fronts.
10 comments - Posted Dec 11, 2007
For more than fifty years, I have been a type 1 diabetic. I am writing to bring attention to the fact that huge amounts of insulin are wasted due to the insulin packaging practices of the pharmaceutical industry.
39 comments - Posted Dec 11, 2007
Previous research has found vitamin D deficiency to be associated with impaired beta cell functioning and insulin resistance, and it's been suggested that vitamin D reduces the risk of type 2.
0 comments - Posted Dec 8, 2007
I have to admit that the first time I met David Kliff, I didn't know what to make of his forthright manner. He immediately told me exactly what was on his mind.
0 comments - Posted Dec 7, 2007
I have lived with type 2 diabetes for thirteen years, and I know very well how to take care of myself. In fact, I have it down to a routine. The flaw of a routine activity, however, is that it is so very routine: you go through the motions without thinking. And that, as I learned to my deep chagrin, can be dangerous.
42 comments - Posted Dec 6, 2007
Scientists have been having fun again making themselves specially engineered mice. This time they knocked the gene that makes glycogen synthase kinase-3 (GSK-3) right out of their ever-accommodating mice.
0 comments - Posted Dec 5, 2007
Messenger molecules are the letter carriers of your body's postal system. You are probably already familiar with hormones, which are messenger molecules that travel about your bloodstream carrying letters from your organs. Neurotransmitters deliver mail on another route: they transmit messages between your nerves.
0 comments - Posted Dec 4, 2007
In an Italian study to compare once-daily injections of insulin glargine (Lantus) with once-daily injections of insulin detemir (Levemir), 24 patients with type 1 diabetes were treated for two weeks with either one or the other in a randomized double-blind study.
14 comments - Posted Dec 4, 2007
Diabetes is not a disease of blood sugar. It is a disease of insulin and, perhaps more importantly, leptin signaling. Until that truth is accepted, we will continue to see epidemic growth in type 2 diabetes and obesity, growth that underscores the inadequacy of current conventional medical treatment and the falsity of prevailing nutritional advice.
27 comments - Posted Dec 3, 2007
Scientists from Sydney, Australia, recently identified and mapped the structure of an enzyme that cuts down insulin production in diabetes. Called protein kinase C epsilon (PKCe), it is regulated by fat. For that reason, it may be the missing link that relates obesity to type 2 diabetes.
1 comment - Posted Dec 2, 2007
Scott King: Do you have any innovative approaches to treating type 2 diabetes?
0 comments - Posted Dec 1, 2007
November 2007
You can make any insulin last longer by injecting a large enough shot. (See Scott King's column, "Why Smaller Shots of Insulin Get Absorbed Faster, Peak Sooner, and Are Out of Your System Quicker", for the math on this.) In fact, about 25 years ago, Dr. John Galloway of Eli Lilly and Company performed an important experiment that demonstrated this very fact.
7 comments - Posted Nov 30, 2007
I learned that I had type 2 diabetes in February 1994. A dozen years later, I knew I had to make a change. Technically speaking, I was "morbidly obese." I'm tall - 6 feet, 2½ inches - but I tipped the scales at 312 pounds and had a body mass index (BMI) of 40.
7 comments - Posted Nov 28, 2007
For my contribution this month, I wanted to share an important lesson I learned about twenty years ago from Peggy Wong at the UCSF Diabetes Teaching Center. It concerns how long insulin lasts after you push down that plunger and create a "depot" of insulin under your skin.
12 comments - Posted Nov 28, 2007
Insulin resistance specifically in the brain is being proposed as the reason for the memory loss that characterizes Alzheimer's disease. Because Alzheimer's may be caused by insulin-related dysfunction, some scientists are calling Alzheimer's by a new name: type 3 diabetes.
1 comment - Posted Nov 27, 2007
Many medications, both oral and injectable, exist to manage blood glucose in type 2 diabetes. Even insulin has many different formulations, including fast-acting and long-acting analogs as well as various pre-mixed combinations of faster and slower acting insulins in the same vial.
9 comments - Posted Nov 27, 2007
Novo Nordisk's Levemir, which came out about five years after sanofi-aventis's Lantus, constitutes about twenty percent of the long-acting basal insulin sold worldwide. Lantus, the only other long-acting insulin analogue, makes up the other eighty percent.
3 comments - Posted Nov 27, 2007
Over the course of the year, we meticulously update all our charts to bring you the most accurate information about hundreds of products, services, and medications. Now we've gathered every one of those charts, from humble lancets to sophisticated continuous glucose monitors, into one handy place.
1 comment - Posted Nov 26, 2007
In July, I flew from New York City to Phoenix to meet my new book agent. (Trust me, I would not have deliberately sought out 100-degree weather without good reason.) Always thinking ahead, I decided to bring along a fancy new bag specially insulated to keep my insulin cool. Alas, either the bag failed me, or I failed the bag.
3 comments - Posted Nov 25, 2007
In the early 1980s, human insulin produced by recombinant DNA technology came onto the market. It was the first time that this technology had been used in medicine, so hopes were high.
8 comments - Posted Nov 23, 2007
Most diabetes drug trials focus strictly on the medication's effect on blood sugar levels, but ignore that medication's impact on other outcomes that are important to patients, such as quality of life and the risk of complications.
7 comments - Posted Nov 23, 2007
A study out of Beth Israel Deaconess Medical Center has found that to restore normal glucose levels in type 1 diabetic mice, it's not enough to halt the destruction of their beta cells. You also have to reverse the muscle and fat inflammation that prevents insulin from transferring glucose into those tissues.
1 comment - Posted Nov 22, 2007
Once upon a time in a land called Sweeten, there lived a beautiful princess named Princess Tootsweet. She had long flowing hair, large dark eyes, and a lazy pancreas.
7 comments - Posted Nov 21, 2007
It was hailed as a "miracle cure," restoring life to the "erstwhile dead" and delivering not just health, but "salvation." Discovered in 1922, insulin did not live up to the initial euphoria - it didn't cure anything - but the life-saving elixir still stands as one of the greatest breakthroughs in medical history.
7 comments - Posted Nov 20, 2007
Januvia, also known as sitagliptin phosphate, is a DPP-IV inhibitor. It prevents, or inhibits, DPP-IV from inactivating GLP-1. GLP-1 is a naturally produced hormone that increases insulin secretion in response to food.
1 comment - Posted Nov 20, 2007
It's true that when you have diabetes, you are "pancreatically impaired." On the other hand, God didn't take your brain away. So use your brain to think as a pancreas. You need to look at foods and think, "What I would do if I were a pancreas?"
3 comments - Posted Nov 19, 2007
First we find out that our belly fat is an endocrine organ, and now it's our bones. Dr. Gerard Karsenty of Columbia University has discovered that bone-building cells (osteoblasts) secrete a hormone called osteocalcin that not only tells the beta cells to secrete more insulin, but also causes the number of beta cells themselves to increase.
0 comments - Posted Nov 18, 2007
Fact One: Insulin receptor substrate-2 (Irs2) is a protein that sits on cell surfaces; its job is to allow those cells to respond to insulin.
Fact Two: Starved mice, which have low blood levels of insulin and heightened insulin sensitivity, live longer than well-fed mice.
2 comments - Posted Nov 16, 2007
Diabetes educators are no less than a lifeline for patients, providing vital insights into the self-care behaviors that keep diabetes in check: managing blood sugar, dosing medications and insulin, exercising, and understanding all the numbers involved.
30 comments - Posted Nov 15, 2007
In a recent three-month study, 43 non-insulin-dependent people with type 2 diabetes were given either a daily dose of 1000 milligrams of cinnamon or a placebo.
24 comments - Posted Nov 15, 2007
The Food and Drug Administration (FDA) just approved pre-filled pens for administering Symlin, which was previously available only in vials. The SymlinPen 60 delivers 15, 30, 45, or 60 micrograms per dose.
9 comments - Posted Nov 14, 2007
Living Cells Technologies (LCT) has announced that their Moscow trial of pig cell implantation, which began in June, is well underway: In September, the second of six type 1 patients was injected with 5,000 "islet equivalents per kilogram" of Diabecells into the peritoneal cavity.
4 comments - Posted Nov 14, 2007
West Chester, PA - November 8, 2007 - Animas Corporation today announced that it has been named the exclusive distributor of inset™ 30, the first all-in-one angled insulin infusion set and inserter. inset™ 30, from Unomedical, features an innovative product design to help people with insulin-requiring diabetes manage their diabetes.
0 comments - Posted Nov 14, 2007
A recent study has found that the combination of metformin and sitagliptin lowers A1c's better than either drug alone, apparently because their different mechanisms work together synergistically.
0 comments - Posted Nov 12, 2007
Los Angeles Times columnist and newly diagnosed type 1 David Lazarus is becoming quite an advocate for people with diabetes.
4 comments - Posted Nov 10, 2007
The word leptin comes from the Greek word leptos, meaning thin. A hormone produced by fat cells, it binds to a spot in the brain known as the satiety center, thereby announcing to the brain that the body has had enough to eat, that plenty of energy is stored in the fat, and that there is no need to eat any more right now. In short, its effect on the brain is to reduce appetite.
0 comments - Posted Nov 9, 2007
Floods, hurricanes, tornadoes, blizzards, and fires strike fast, creating challenges that can be especially difficult for people with diabetes.
1 comment - Posted Nov 9, 2007
Researchers have discovered a fourth antibody, ZnT8, that helps predict who will get type 1 diabetes later in life. By using the three previously known antibodies, scientists already could predict disease with ninety percent accuracy. By adding this fourth antibody, the prediction rate rises to 98 percent.
1 comment - Posted Nov 8, 2007
I have been injecting insulin into my body since 1963, after an infection with a coxsackie virus (mumps) when I was nine years old. Admittedly, I am insulin-dependent. On the other hand, everyone is insulin-dependent. I just need to inject someone else's insulin (insulin from E.coli in my case).
21 comments - Posted Nov 8, 2007
In research reports, they're always talking about glucose clamps. Two types of clamps are quite commonly used, but they have nothing to do with the common definition of the word clamp. Instead, they are used to measure either how well you metabolize glucose or how sensitive you are to insulin.
1 comment - Posted Nov 7, 2007
The FDA has received thirty reports of acute pancreatitis (rapid-onset inflammation of the pancreas) in type 2 patients taking Byetta. Twenty-seven of the thirty patients had one or more risk factors for acute pancreatitis, such as gallstones or alcohol use.
1 comment - Posted Nov 5, 2007
Nearly 21 million children and adults in the United States have diabetes, and another 54 million people are knocking at that door. Diabetes is the fifth deadliest disease in the nation and may well be the most serious health problem facing America today. Nevertheless, the public doesn't seem to grasp the gravity of the situation, at least not like they did with polio, for instance, or AIDS.
7 comments - Posted Nov 1, 2007
October 2007
This morning, a major meter manufacturer announced that its blood glucose meters will now operate on Microsoft's HealthVault. HealthVault is an online service that allows a patient to store and manage his health records without paying a fee.
32 comments - Posted Oct 31, 2007
Exubera, the inhalable insulin, has been, to speak bluntly, a real bomb. Pretty much the entire diabetic population can say with honesty that they never inhaled.
8 comments - Posted Oct 31, 2007
The FDA has spoken: the heart risk warnings on labels of Avandia (rosiglitazone) and Actos (pioglitazone) will now be surrounded by an emphatic black outline known as a black box. Black boxes will also be added to the warnings on Avandaryl (rosiglitazone and glimepiride), Avandamet (rosiglitazone and metformin), and Duetact (pioglitazone and glimepiride).
3 comments - Posted Oct 31, 2007
Old-fashioned cod liver oil supplements in infancy have already been associated with a decreased risk of type 1 diabetes among Norwegian children, who are apparently given the omega-3-rich, albeit nauseating, tonic on a regular basis.
3 comments - Posted Oct 30, 2007
A low glycemic diet is sometimes advised for people with diabetes because it raises blood sugar slowly and reduces blood sugar spikes. Well, now Australian dermatologists have found that it clears up your skin as well.
4 comments - Posted Oct 23, 2007
I am a survivor and proud of it. Not only have I lived with diabetes for 52 years, since the age of five, but I am also a breast cancer survivor for over fifteen years.
3 comments - Posted Oct 22, 2007
Taste buds have little receptors to sense the lovely taste of sugar, but now scientists have found that tasting sweets doesn't end with your tongue.
0 comments - Posted Oct 20, 2007
Recently, researchers from the University of Chicago interviewed 701 adults with diabetes in order to quantify and rank their feelings about diabetes-related complications and about the self-care necessary to avoid those complications.
4 comments - Posted Oct 19, 2007
The take-home message from the Tufts study is that the GI value of white bread is 70. That's nothing new: The same value has been found in dozens of other studies around the world (1).
2 comments - Posted Oct 18, 2007
Chip Sullivan is a golf pro. This June he played his best game ever, beating the top club professionals in the country and qualifying for the fourth time to play against the likes of Tiger Woods in the PGA championship tour.
2 comments - Posted Oct 17, 2007
Whether or not you get fat is not the critical factor in developing type 2 diabetes, according to a recent mouse study by Texas researchers; instead, it's where that fat is packed away.
1 comment - Posted Oct 16, 2007
First a little background: T cells are white blood cells that attack and eat infected cells or tumor cells. They're told what to attack by other white blood cells called B cells. The B cells "introduce" the T cells to their targets by presenting little pieces of target cells, called antigens, to the T cells. Once the T cells have been properly introduced and know what to target, they can do their deadly work.
0 comments - Posted Oct 16, 2007
Symlin, or pramlintide, is synthetic amylin, a natural hormone that slows stomach emptying and leads to a feeling of fullness. Currently Symlin is used to dampen blood sugar rises in people with diabetes, but it's showing potential as a weight loss drug as well, according to a recent study.
1 comment - Posted Oct 12, 2007
According to Greek researchers, Actos and Avandia were behind a tripling of the cost of medicines used to treat Athenians with type 2 diabetes over the past eight years.
0 comments - Posted Oct 10, 2007
Halloween and candy…candy and Halloween. No other holiday is so inextricably tied to sweets. It wasn't very long ago that I too was handing out Reese's Cups and Snickers bars to the troops of tiny ghosts and ballerinas who crowded around our door chirping "trick or treat!"
1 comment - Posted Oct 9, 2007
The September 2007 Journal of the American Medical Association (JAMA) has published two new studies, one a meta-analysis of Avandia (rosiglitazone) and the other a meta-analysis of Actos (pioglitazone).
0 comments - Posted Oct 5, 2007
Just between you and me, in all my years with diabetes (thirty-five and a half to be exact) I've never worn a medic alert bracelet. While I'm no fashionista, I don't like the way they look, and I don't like the reference I make in my head - "damaged goods." Then, too, just to be clear, I've never (yet) had an incident where I needed one.
3 comments - Posted Oct 4, 2007
Saul Katz is one charismatic health bar maker, a fascinating talker and visionary who makes health bars seem like the most important thing in the world. In 1989, he began his quest to create a "functional food" that would combine science, nature, and great taste in a snack bar. Not only did he want his bar to promote health, enhance performance, and prevent disease; he also dreamed of air-dropping his bars to disaster victims in need of a good self-contained meal. It's taken over a decade of intense scientific alchemy to achieve, but he's managed to do it all.
1 comment - Posted Oct 1, 2007
Anyone who knows Al Lewis of Vancouver, BC, understands why he wouldn't switch to an insulin pump until a waterproof model became available in 1977: His whole life has revolved around water.
2 comments - Posted Oct 1, 2007
Bryan Stubblefield is a big ruddy man with the gentlest manner you could imagine. This is the story of his little boy, who's overcoming almost insurmountable problems, and of the man who has learned from him what it really means to be a father.
1 comment - Posted Oct 1, 2007
September 2007
In obstructive sleep apnea (OSA), the upper airway narrows or collapses during sleep, cutting off breathing. People with OSA may be aroused hundreds of times each night, just enough to start breathing again.
0 comments - Posted Sep 30, 2007
When I was diagnosed with type 2 diabetes last year, my doctors and I were rather shocked. I was only 27 years old at the time, slender and in good shape. Diabetes does run in my mother's side of the family, so I wasn't completely taken aback.
2 comments - Posted Sep 28, 2007
American Youth Understanding Diabetes Abroad, Inc., also known as AYUDA, is a small organization with a lofty goal: to bring the diabetes camp experience to underprivileged children and youth with type 1 diabetes around the world.
0 comments - Posted Sep 28, 2007
Despite their best efforts, researchers have been having a hard time getting pancreatic stem cells to grow up into beta cells that can be used for transplantation.
0 comments - Posted Sep 27, 2007
In two recent studies, WelChol, a drug already approved for lowering LDL (bad) cholesterol was found to lower A1c's in patients with type 2 diabetes. The first study showed that WelChol, when added to insulin, lowered A1c's by an average of 0.5% compared to a placebo group.
0 comments - Posted Sep 26, 2007
If ever there were a diabetic trailblazer, the honor should go to James William Quander, the longest-living African-American with type 1 diabetes on record. Born in 1918 in Washington, D.C., he was diagnosed with diabetes in early 1924, shortly before the age of six.
0 comments - Posted Sep 21, 2007
As a scientist who has type 1 diabetes, Dr. Kowalski knows that the cure may be a long time coming. But he's optimistic, nevertheless, because he believes that technology will revolutionize diabetes management long before the cure raises its shy little head.
1 comment - Posted Sep 18, 2007
Swaying in rhythm like drunk fans singing their team fight song, we campers bellowed our camp theme, clapping and banging on dining tables: "Shock, shock for Camp Firefly! We take the insulin - try not to cry!"
7 comments - Posted Sep 18, 2007
I've been doing a lot of flying lately, and it's given me time for reflection. While aloft a few days ago in JetBlue's comfy seat, as I took out my syringe and Humalog to dose for my snack, I realized how many things I no longer do that I was once taught to do.
1 comment - Posted Sep 16, 2007
When islet cells are transplanted into a person, they don't go into their usual home in the pancreas. Instead, they're injected into the portal vein, the large vein that feeds the liver with rich fats and sugars from the digestive system.
0 comments - Posted Sep 15, 2007
Sheri Colberg, PhD, is writing the 2nd edition of her book, The Diabetic Athlete. Updated throughout, it will cover the use of the newest insulins, new medications like Symlin and Byetta, and all the latest devices.
0 comments - Posted Sep 14, 2007
Since the 1950s, the National Institutes of Health (NIH) has funded almost all diabetes research worldwide. From its headquarters in Bethesda, Maryland, the NIH oversees a $28 billion annual medical research budget. More than $1 billion of those taxpayer dollars go specifically toward diabetes research. Still, a cure remains frustratingly elusive.
0 comments - Posted Sep 13, 2007
Diabetes is sometimes called "the thinking person's disease," and it's not hard to understand why. One consequence of living with diabetes is a constant undertow of diabetes-related thought.
1 comment - Posted Sep 10, 2007
Life in the trenches with type 1 diabetes is challenging. Unpredictable blood sugars can leave a person with diabetes (PWD) feeling frustrated and helpless. The acute toxic effects of abnormal blood sugars also contribute to depression, anxiety, irritability, and food cravings.
4 comments - Posted Sep 9, 2007
We recently wrote about a study which concluded that blood glucose meters are a waste of time for people with type 2 diabetes who are not using insulin ("Is Using a Meter a Waste of Time for Type 2s?"). Our readers vehemently disagreed with that conclusion.
2 comments - Posted Sep 6, 2007
Recently, as the result of the settlement of a 2005 lawsuit filed by parents and the ADA, California schools were told that they must have staff available, trained but not necessarily licensed, to help diabetic students with their shots, monitoring, and other needs.
1 comment - Posted Sep 4, 2007
Until today, California schools have insisted that only nurses could administer insulin and give other diabetes-related care to school children. Unfortunately, California only has one school nurse for every 2,257 students.
0 comments - Posted Sep 2, 2007
August 2007
The mad science of genetic engineering is busily engaged in finding all sorts of novel ways to make insulin. We recently reported on cloned cows that will give insulin-containing milk ("Got Insulin-Containing Milk?").
0 comments - Posted Aug 31, 2007
I've generally been a "good" person. I try to do those ten things on Dalai Lama's list. You know, be kind, not hurt others, let people know you love them, hear a tree when it's falling even if you're not there...
2 comments - Posted Aug 30, 2007
Vacationing on a cruise ship is great fun, but it's a form of travel that people with diabetes often fail to consider. Although cruising with diabetes was problematic years ago, the cruise industry has finally realized that people with diabetes are a growing untapped source of potential customers.
0 comments - Posted Aug 29, 2007
Americans spend 275 billion dollars on prescription medicines every single year, sixty percent of it on generics. But in the next five years, the twenty-year patents are going to expire on enough brand-name medicines to account for about 60 billion dollars of that total. And the generics that spring up to replace those drugs will be thirty to eighty percent cheaper.
3 comments - Posted Aug 26, 2007
A Canadian Olympic rower and marathon runner, Chris Jarvis, age 26, exhibits the endurance of most elite athletes. However, few would know that for nearly 13 years he has lived and struggled with type 1 diabetes.
0 comments - Posted Aug 25, 2007
MedPage Today, a medical news service for physicians, has published the results of a reader poll about Avandia attitudes. Only nine percent of respondents said they would continue prescribing it without reservations, and one in four said it should be taken off the market.
0 comments - Posted Aug 23, 2007
Visceral fat (fat around your internal organs) is associated with insulin resistance and cardiovascular risk, but it's hard to measure without using fancy imaging techniques.
0 comments - Posted Aug 21, 2007
Drinking one soft drink a day, diet or not, is associated with a 44 percent increased likelihood of developing metabolic syndrome, that unwelcome conglomeration of conditions that puts you at risk of type 2 diabetes, heart attack, and stroke.
0 comments - Posted Aug 21, 2007
There are plenty of corporate weight-loss programs around, but Lite For Life is a weight loss program with a difference: Its philosophy is based upon the work of Seale Harris, a diabetes pioneer who discovered hyperinsulinism (excess secretion of insulin related to insulin resistance) in 1924.
3 comments - Posted Aug 20, 2007
An old and inexpensive drug, hydroxychloroquine, has been found to help prevent type 2 diabetes in people with rheumatoid arthritis.
0 comments - Posted Aug 19, 2007
Recently, four men and sixteen women with metabolic syndrome, weighing an average of 200 pounds, were put on the low carb South Beach diet for three months.
1 comment - Posted Aug 17, 2007
Courtney Lovell remembers vividly when her little sister, Marah, was diagnosed with type 1 diabetes. As the eldest in a family of seven children, Courtney was her mom's right hand.
1 comment - Posted Aug 16, 2007
A meta-analysis of 29 studies, none longer than six months, has shown that incretin therapies (like Byetta and Januvia) are moderately effective in lowering blood glucose in people with type 2 diabetes, especially after meals.
0 comments - Posted Aug 16, 2007
It's about time that we Americans catch up with the rest of the world when it comes to using insulin pens. Maybe we will, now that SoloSTAR, sanofi-aventis's disposable insulin pen, is available in the United States.
2 comments - Posted Aug 15, 2007
According to a literature review and survey of 132 Canadian pharmacists, 47 percent of pharmacists have encountered an adverse interaction between a natural health product and a drug.
0 comments - Posted Aug 13, 2007
A study of 2,375 middle-aged British men reports that those who drank at least a pint of milk a day were 62 percent less likely than non-milk-drinkers to have metabolic syndrome (defined as raised levels of two or more of the following: blood glucose, insulin, blood fats, body fat, and blood pressure).
0 comments - Posted Aug 11, 2007
Diabetes is a chronic yet manageable malady; as such, it requires constant interaction between the person and the disease. You must pay attention to the endless flow of information produced by your various management tools.
1 comment - Posted Aug 10, 2007
Just after he turned sixteen, Noah Moore got type 1 diabetes for Christmas. It didn't seem like a gift at the time, but it sent him on a journey of creative diabetes advocacy that has made his life into a gift to us all.
0 comments - Posted Aug 9, 2007
That old standby, metformin, is still your best bet. In fact, there is no benefit in taking the newer oral medications unless you can't tolerate the older ones.
0 comments - Posted Aug 8, 2007
On December 13, 2005, Keith Scofield visited a Wal-Mart pharmacy in Frederick, Maryland, and ordered over-the-counter Humulin R (u-100). Instead, he was allegedly given Humulin R (u-500), a prescription drug that contains five times the insulin of the requested medication.
3 comments - Posted Aug 7, 2007
Central adiposity, visceral fat, intra-abdominal fat, or a big belly, they all mean the same thing: increased risk of insulin resistance, cardiovascular disease, and type 2 diabetes.
0 comments - Posted Aug 7, 2007
Good news for those of us who like to put our posteriors to use: sitting down at the right time will help you burn fat. To be precise, taking a twenty-minute sit break between two thirty-minute workout sessions burns more fat than powering through a single session of sixty minutes.
0 comments - Posted Aug 6, 2007
Both Bristol-Myers Squibb and GlaxoSmithKline are developing new drugs that block the re-absorption of excess glucose by the kidneys, allowing it to be excreted by the body instead.
0 comments - Posted Aug 4, 2007
Parents of newly-diagnosed children with diabetes have something in common - they don't sleep soundly through the night. Anxiety soars in the darkness. When our son Danny was diagnosed at age seven, my husband Brian and I barely closed our eyes, and we set our alarm to check on him at least once every night.
3 comments - Posted Aug 2, 2007
It's a complex mental process that your doctors go through when they choose your medicines, according to a recent survey of several hundred physicians.
0 comments - Posted Aug 2, 2007
According to a University of Oxford study led by Dr. Andrew Farmer, home monitoring of glucose with a meter did not improve glucose control in non-insulin-requiring people with type 2 diabetes.
0 comments - Posted Aug 1, 2007
On July 30, 2007, a Food and Drug Administration (FDA) panel voted 22 to 1 to keep Avandia on the market, right after agreeing by a vote of 20 to 3 that Avandia does increase heart risks. Now the FDA will decide what kind of warning should appear on the Actos and Avandia labels. It has already called for a black box warning, the sternest possible, on Avandia.
0 comments - Posted Aug 1, 2007
July 2007
Here's one more small fact to add to the mountain of reasons not to smoke: A recent study indicates that if you are a smoker with type 1 diabetes, your odds of severe hypoglycemia (involving loss of consciousness or overnight hospitalization) are 2.6 times greater than those of someone with type 1 who's never smoked.
2 comments - Posted Jul 30, 2007
According to the Pittsburgh Epidemiology of Diabetes Complications Study, a sixteen-year examination of 225 type 1 patients, fat puts you at greater risk of heart disease; once you do get heart disease, however, it's less severe.
0 comments - Posted Jul 29, 2007
If you've got a big protein molecule like insulin, right now the only option for getting it into your body is via a needle or cannula into the subcutaneous tissue. It can't be swallowed because the digestive system would, logically enough, digest it.
1 comment - Posted Jul 29, 2007
Diabetes and pre-diabetes are associated with a seventy-five percent increased risk of Alzheimer's disease. Research has already shown that insulin resistance, with its accompanying high levels of circulating insulin, increases brain and spinal cord inflammation markers and neurotoxic peptides (molecules that cause brain and nervous system damage), just like early Alzheimer's.
0 comments - Posted Jul 28, 2007
This issue, we lay out the many devices with which diabetic people must poke themselves: syringes, pen needles, and lancing devices. And we top them off with a sprinkling of sugar: a chart outlining all the sources of fast-acting glucose.
0 comments - Posted Jul 26, 2007
CHARLOTTESVILLE, VA, July 24, 2007 - Although they have a greater than average risk of developing retinal problems and blindness, many people with diabetes never visit their eye doctor.
0 comments - Posted Jul 25, 2007
Not to be outdone by his older brother Gerald (the oldest living person with diabetes most of his life), Bob Cleveland is believed to be the longest-living person with type 1 diabetes to date after Gladys Dull, who beats him by less than a year.
2 comments - Posted Jul 24, 2007
A team of five seniors and two freshmen at Johns Hopkins University has devised a little "pouch" to hold microcapsules of beta cells in the portal vein, from which the cells can send out insulin while safely protected inside. It's made by sandwiching a porous cylinder of nylon mesh between two cylindrical metal stents, similar to the ones that are used to keep clogged blood vessels open.
0 comments - Posted Jul 23, 2007
You can rack your brain and make lists by the dozens, but it's still hard to be sure you've covered everything when you're preparing for a trip and you have diabetes. The last thing you need is to be stuck at an airport and find you've forgotten something critical.
0 comments - Posted Jul 22, 2007
If your Paradigm pump has been not been exposed to powerful magnetic fields, such as those found near MRI machines, you have nothing to worry about. Go about your merry way and keep up the good work. In the unlikely event that such exposure has occurred, however, you need to be aware that it may cause the pump's motor to malfunction and significantly over-deliver insulin, causing severe hypoglycemia.
2 comments - Posted Jul 20, 2007
A life-time resident of the Syracuse, New York, area, Gerald Cleveland has had a history of not quite coming out on top - at least until now.
2 comments - Posted Jul 19, 2007
Lantus and Levemir have a lot in common. Both are basal insulin formulas, which means that they last for a long time in the body and act as background insulin, with a slow feed that mimics the constant low output of insulin produced by a healthy pancreas.
103 comments - Posted Jul 17, 2007
On one hand, GlaxoSmithKline really, really wants you to take their new over-the-counter diet pill, alli. On the other hand, they don't want you to abandon healthy habits in favor of pill popping.
0 comments - Posted Jul 15, 2007
Two-thirds of pregnancies in women with diabetes are unplanned. How long after conception do those women realize they're pregnant? They may be eight weeks into their pregnancy before they know it's happened.
5 comments - Posted Jul 14, 2007
It's a fact that Byetta reduces A1c's, post-meal and fasting glucose levels, and weight in people with type 2 diabetes. The drawback is that it's another injection twice a day. In response, Amylin, the maker of Byetta, has developed exenatide LAR, a form of Byetta that is injected only once a week.
0 comments - Posted Jul 13, 2007
You know how the pump works: it has an infusion set with a soft cannula that's inserted only once every few days, and your insulin infuses into your body by way of the cannula. You certainly don't get poked with a needle every time the pump sends you some insulin.
1 comment - Posted Jul 13, 2007
Recently we wrote that Living Cell Technologies (LCT), a New Zealand company, was about to begin transplanting pig islets into humans in a year-long Phase I/IIA clinical trial in Moscow, Russia ("Piglet Islets Soon Tested in Humans").
1 comment - Posted Jul 12, 2007
In a congressional hearing on June 13, 2007, the Food and Drug Administration (FDA) revealed that it has called for a black box warning, the sternest possible, on both Actos and Avandia.
0 comments - Posted Jul 12, 2007
Born on the family dairy farm in New York, the second of five children, Carolyn Gridley was diagnosed with type 1 diabetes after her grandmother noticed sugar crystals on her diaper that attracted the bees and flies around the farm.
1 comment - Posted Jul 11, 2007
Are you obese? Did your parents have type 2 diabetes? Do you have symptoms of metabolic syndrome, including high blood pressure and high cholesterol? Your answers to those few questions can predict your risk of developing type 2 diabetes.
0 comments - Posted Jul 10, 2007
How elevated does your blood sugar have to be before you're diagnosed with gestational diabetes? Not near as elevated as we used to think, according to the findings of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study.
0 comments - Posted Jul 10, 2007
You have made a point of checking your blood glucose and getting your annual eye and foot checkups. You track your blood cholesterol and blood pressure. But now the pain in your hip is unbearable and interfering with your walking program, so your doctor suggests hip surgery. You will be admitted to the hospital for hip surgery, not diabetes.
0 comments - Posted Jul 9, 2007
Sidney, NY, July 6, 2007 - A study by the Joslin Diabetes Center in Boston has found that the AT-A-GLANCE® Balance & Stretch® Day Planner is an effective tool in improving the management of type 1 diabetes in children. The American Diabetes Association (ADA) highlighted the results of the study at its 67th Scientific Session in Chicago.
0 comments - Posted Jul 7, 2007
Each year, one hundred thousand peregrinos, or pilgrims, set out for Santiago De Compostela in northwestern Spain to visit the bones of St. James buried beneath the cathedral. Called El Camino de Santiago, it's one of the world's largest Christian pilgrimages.
1 comment - Posted Jul 6, 2007
Dishware is destiny, according to new research just published in the Archives of Internal Medicine. There exists a plate that has just been scientifically proven to cause weight loss. And it's a mighty cute little piece of pottery to boot.
0 comments - Posted Jul 6, 2007
Q: My mother, who is a "brittle diabetic," has been sent to a skilled nursing facility for two weeks of rehabilitation following a seven-week hospital stay. I am amazed and frightened at the lack of concern for and attention to her diabetes care at the nursing home.
1 comment - Posted Jul 3, 2007
Bozeman, Montana - Many people consider a diagnosis of diabetes a sentence to a life full of limitation. "That's not so," says Jeff Mazer, the Bozeman organizer of MADiDEA 2007, an event highlighting how to live a full life with diabetes while addressing the challenge of managing the disease.
0 comments - Posted Jul 3, 2007
I was diagnosed with diabetes in September 1953. During that summer, I was in my second year of graduate school at UCLA when I noticed that I was losing weight and had severe polyuria (frequent urination).
1 comment - Posted Jul 1, 2007
June 2007
Bariatric Surgery isn't just for weight loss anymore. It's been shown to be possibly curative of type 2 diabetes even in the absence of major weight loss following the surgery. Here's the rundown on how it works.
0 comments - Posted Jun 28, 2007
Kevin Powell is an athlete, first and foremost. Twice a year, he competes in an Ironman event, a grueling test of endurance that entails a 2.4-mile swim and a 112-mile bike ride, topped off by a full marathon of 26.2 miles.
2 comments - Posted Jun 28, 2007
Kamaal Washington was diagnosed with type 1 diabetes when he was nine. He's thirteen now. In those four years, he's become an advocate for diabetes and the author, with his brother Malcolm and help from his parents, of a diabetes educational superhero comic book that's swept the nation beyond their wildest expectations. But it all started when he began to be really, really thirsty.
1 comment - Posted Jun 27, 2007
As many of us know to our dismay, the desire to chow down fatty, sugary food can be very strong indeed. In a recent six-week study of 88 obese, non-diabetic men and women, Symlin, a synthetic hormone currently used to dampen diabetic blood sugar swings, was found to dampen those very desires.
1 comment - Posted Jun 27, 2007
A study from the Mayo Clinic has found that using a decision-making tool with patients when discussing medication options makes them more likely to take their prescribed medicine.
0 comments - Posted Jun 26, 2007
Given that babies are born by the cartloads every day, cord blood is an easy source of fetal stem cells, especially because it’s free of the controversy surrounding embryonic stem cells.
0 comments - Posted Jun 25, 2007
In a recent Dutch study, researchers gave either a placebo or a daily dose of 400 micrograms of chromium in the form of chromium yeast to 57 obese, insulin-requiring type 2 patients with A1c’s above eight percent.
0 comments - Posted Jun 25, 2007
Adolescents don't always check their blood glucose levels as often as they should. Because frequent monitoring is a keystone of diabetes care, this can make their parents frantic.
0 comments - Posted Jun 24, 2007
I was diagnosed with type 1 diabetes at the age of three, and I have lived with it for 62 years. I can still remember my mother learning to inject insulin into an orange at Hermann Hospital in Houston, Texas.
1 comment - Posted Jun 24, 2007
Anne Williamson has had type 1 diabetes for forty years, since the age of seven. But because of the Easter basket incident, she still vividly remembers her time in the hospital. Anne was alone in her hospital room when a volunteer insisted on leaving a candy-filled Easter basket by her bed.
0 comments - Posted Jun 23, 2007
The results of our pump survey are in, and we had 841 respondents! Clearly, people are passionate about pumping, both pro and con. In fact, they seem to be more passionate about pumping than about sex, judging by the far greater response we got to this survey than we did to our survey about women and sex!
9 comments - Posted Jun 21, 2007
Late one evening while watching TV with my husband Phil, I reminded him to check his glucose level. His reply was the usual: "I'll do it later." Knowing him as I do, I was frustrated. He has the tendency to procrastinate, so I chose a different approach. "Why don't you check mine, and we'll compare."
0 comments - Posted Jun 21, 2007
Which diet works best for you may depend on whether or not you are secreting high levels of insulin. From September 2004 to December 2006, researchers monitored 73 obese young adults who ate either a low-fat diet (55 percent carbs and 20 percent fat) or a low-glycemic diet (40 percent carbs and 35 percent fat).
0 comments - Posted Jun 19, 2007
Two new research reports, presented at the American Thoracic Society 2007 International Conference, indicate that obstructive sleep apnea ups your risk of type 2 diabetes and increases your risk of heart attack.
0 comments - Posted Jun 18, 2007
In the complex process that moves glucose from your blood across cell membranes into your cells, the glucose transporters called GLUTs are primary players. They hand off glucose from one side of a cell membrane to the other by exposing a glucose-binding site toward the outside of the cell.
0 comments - Posted Jun 17, 2007
In 1960, I was a scrawny thirteen-year-old…very scrawny. When my mother recognized that I was eating a lot (and drinking a lot) and not gaining any weight, she took me to the family doctor, who diagnosed insulin-dependent diabetes. I recall that my parents were devastated.
0 comments - Posted Jun 16, 2007
A company called Sugarest has developed a pill made from the Indian herb Gymnema sylvestre that purports to deaden your ability to taste sugar, thereby rendering sweets tasteless.
0 comments - Posted Jun 15, 2007
Imagine your delighted shock if, after living with type 1 diabetes since infancy, you suddenly learned that you weren't type 1 after all. If you were diagnosed with type 1 diabetes within the first six months of life, especially if your birth weight was low, there's a chance that instead you have permanent neonatal diabetes mellitus (PNDM).
0 comments - Posted Jun 15, 2007
Researchers reporting in the Archives of Internal Medicine have found that depression is associated with an increased risk of type 2 diabetes in people over 65 years of age.
0 comments - Posted Jun 13, 2007
Twenty-five years ago, at the age of seven months, Phil Southerland was diagnosed with type 1 diabetes. Doctors at the time gave his mother very dismal predictions about his prospects, but he blew all those right out of the water.
0 comments - Posted Jun 13, 2007
Grape-eating rodents have a significantly lowered incidence of type 1 diabetes, according to research published in the May 2007 Journal of Nutrition. The study showed that grape-eating reduced the movement of immune cells into the islets of Langerhans, thus preventing damage to the beta cells located therein.
0 comments - Posted Jun 12, 2007
The Cochrane Library recently conducted a review of studies to see if NPH is as good as Lantus and Levemir when used as a basal insulin for people with type 2 diabetes. Six studies comparing insulin glargine (Lantus) to NPH (Neutral Protamine Hagedorn) were examined, as well as two studies comparing insulin detemir (Levemir) to NPH.
0 comments - Posted Jun 11, 2007
Patients with diabetes are less likely to have a heart attack or die if they stay on anti-clotting medication for a full year after a stenting procedure.
0 comments - Posted Jun 11, 2007
The insulin pump is a wonderful device, a marvel of engineering that allows diabetics to screw up at the push of a button. With the pump in use, however, instead of staring at a syringe and racking your brain to remember what you injected into where and how much, a few button clicks will remind you of your mistake, allowing you to correct it with unprecedented accuracy.
0 comments - Posted Jun 11, 2007
Thinner artery walls are a good thing, because thicker ones indicate atherosclerosis and an increased risk of heart attack. In a study published in the December 2006 Journal of the American Medical Association, pioglitazone (Actos, a thiazolidinedione) was compared to glimepiride (a sulfonylurea) with regard to carotid artery thickness.
0 comments - Posted Jun 9, 2007
Medco, a pharmacy benefit managing company, has released its 2007 Drug Trend Report, and diabetes drugs are big news. The report projects that between 2007 and 2009, there could be a near 70 percent increase in spending on endocrine and diabetes drugs.
0 comments - Posted Jun 8, 2007
When Maureen "Moe" Murray was diagnosed with type 1 diabetes in 1954, she was told that she probably wouldn't live to adulthood. If she did, she wouldn't be able to get pregnant, and if by some miracle she did conceive, she would certainly miscarry. Fifty-two years later, she's a dynamo of a woman who's disproved every one of those dire predications.
0 comments - Posted Jun 8, 2007
I'll never forget coaching my oldest child's soccer practice on that cool damp evening in late April. The moment I laid eyes on my ten-year-old daughter as she walked onto the soccer field, I knew that something wasn't right.
0 comments - Posted Jun 6, 2007
University of California, San Francisco - In head-to-head trials of two drugs, the one deemed better appears to depend largely on who is funding the study, according to an analysis of nearly 200 statin-drug comparisons carried out between 1999 and 2005.
0 comments - Posted Jun 5, 2007
A 22-year-old who's planning to graduate from college this spring with a degree in criminal justice has run up against a Massachusetts state law that bars anyone who wears an insulin pump from being hired as a full-time police officer.
1 comment - Posted Jun 4, 2007
In a recent Dutch study, researchers gave either a placebo or a daily dose of 400 micrograms of chromium to 57 obese, insulin-requiring type 2 patients with A1c's above eight percent.
1 comment - Posted Jun 3, 2007
Researchers from Philadelphia have just discovered that beta cells, the insulin-producing cells of the pancreas, divide, albeit slowly, to make new beta cells. Adult stem cells, which are precursors of new skin, intestines, and other tissues, apparently do not differentiate into beta cells or other pancreatic tissue.
1 comment - Posted Jun 2, 2007
I recently had the privilege of interviewing Ginger Graham, the CEO who led Amylin during the launch of its two first-in-class medicines, Byetta and Symlin. A fascinating woman with a very personal leadership style, she had the following to say about her past achievements and her future hopes.
0 comments - Posted Jun 1, 2007
NEW YORK, May 29, 2007 - The Juvenile Diabetes Research Foundation is proud to announce that recording artist Elliott Yamin will serve as a celebrity advocate for its signature event, “Children’s Congress,” and their “Promise to Remember Me” campaign.
0 comments - Posted Jun 1, 2007
May 2007
Analysis of several recent studies indicates that Avandia (rosiglitazone), a type 2 diabetes medication that's been taken by more than six million people worldwide, is associated with a 43 percent increased risk of heart attack and with a borderline-significant increased risk of heart attack-related death.
0 comments - Posted May 31, 2007
The recent ruckus over the drug rosiglitazone (Avandia) has been portrayed as another case of Big Pharma foisting a dangerous drug on the public while the overworked FDA can't keep up.
0 comments - Posted May 31, 2007
In November 1924, three years after the discovery of insulin in 1921, six-year-old Gladys Dull began her long life of insulin injections. To our knowledge, she is the longest-living person with diabetes to date.
10 comments - Posted May 29, 2007
A type 1 diabetic, 21 years old, pedals a bicycle for nine straight days, nine hundred miles from Tecumseh, Michigan, to Grand Island, Nebraska.
0 comments - Posted May 24, 2007
Regarding your article on the Banting Homestead ("Historic Homestead of Insulin Discoverer May Become Housing Development"), I would like to point out a number of facts that have not received sufficient attention.
0 comments - Posted May 24, 2007
Banting Gives It Away - Insulin was discovered in 1921 by Fred Banting and Charles Best. In a generous gesture that unfortunately didn’t start a trend, they sold the patent for a dollar so that cheap insulin would quickly become available. It worked like a charm: within two years, Eli Lilly had sold 60 million units of its purified extract of pig and cow pancreas.
23 comments - Posted May 23, 2007
Recently, while preparing to give a speech, I found myself reminiscing about my life with diabetes. It was 33 years ago that I was diagnosed with type 1, but I remember it like it was yesterday.
0 comments - Posted May 22, 2007
Because of recent changes in airline regulations concerning the transportation of medication, diabetics have more to lose than just their lotion or soda. Now more than ever, it is important to know how to notify security and flight personnel of your medical needs, what documentation to bring, and where to find supplies if yours are damaged.
0 comments - Posted May 21, 2007
Bariatric surgery, formerly used only for treating obesity, is being explored as a cure for type 2 diabetes in normal weight or moderately overweight people.
1 comment - Posted May 19, 2007
A team of five seniors and two freshman at Johns Hopkins University has devised a little “pouch” to hold microcapsules of beta cells in the portal vein, from which the cells can send out insulin while safely protected inside.
0 comments - Posted May 18, 2007
People with type 2 diabetes are far more likely than others to die from heart attacks due to reduced blood supply to the heart. Recently, a team of researchers at Joslin Diabetes Center found one reason why.
0 comments - Posted May 18, 2007
While much of the diabetes community eagerly anticipates the latest research and treatment, many diagnosed with the disease struggle to gain access to doctors and the most basic supplies because they are poor or uninsured.
1 comment - Posted May 17, 2007
Back in 2003, a study in Diabetes Care showed that in thirty people with type 2 diabetes, one to six grams of cinnamon daily for forty days resulted in a drop in blood sugar levels, triglycerides, and LDL (bad cholesterol)...
4 comments - Posted May 17, 2007
Many heart attacks are caused by platelets sticking together and forming clots that block blood flow. Aspirin reduces clotting by inhibiting an enzyme that helps platelets stick together. But if you have diabetes and are taking low-dose aspirin to prevent platelets from gumming up your blood vessels, your low dose might be a little too low.
0 comments - Posted May 16, 2007
A drug initially designed to treat the autoimmune disease of juvenile rheumatoid arthritis has been found helpful in treating type 2 diabetes. The drug is an “interleukin-1-receptor antagonist” that goes by the name of anakinra (Kineret).
0 comments - Posted May 16, 2007
Eight New Zealanders with type 1 diabetes are hoping to receive pig islet transplantations by the end of the year, now that the company Living Cell Technologies (LCT) has surmounted the first of three regulatory hurdles in pursuit of permission for a twelve-month trial in New Zealand.
0 comments - Posted May 15, 2007
INDIANAPOLIS Data from a pooled analysis of three studies suggest that in patients with pain caused by diabetic nerve damage, or diabetic peripheral neuropathy, who are treated with Cymbalta (duloxetine HCl), improvements in both average daily pain and night pain severity were associated with less pain-related sleep interference than in those patients taking sugar pill.
5 comments - Posted May 15, 2007
The FDA and GlaxoSmithKline, Avandia’s manufacturer, have advised doctors to carefully consider fracture risk before beginning Avandia therapy for women with type 2 diabetes.
0 comments - Posted May 14, 2007
Sanofi-aventis and the Patient Mentor Institute are looking for people with diabetes to become patient mentors with the A1C Champions® program – a unique, patient-to-patient approach to diabetes education.
2 comments - Posted May 12, 2007
What is the best kept secret in weight management? When I became a type 2 diabetic and had to lose a significant amount of weight, I wanted a program that was guaranteed to succeed. I tried low carbohydrate dieting, but found it too difficult.
1 comment - Posted May 10, 2007
Continuous Glucose Monitors Are Revolutionary - I’ve always believed that if I could give myself insulin conveniently and constantly knew my blood glucose, I could control my blood sugar almost as well as a non-diabetic person. Nine years ago, an insulin pump made the first condition come true. Since then I have been waiting for the magic blood sugar machine.
2 comments - Posted May 10, 2007
Scientists in the cattle-raising country of Argentina have cloned four calves that will produce human insulin in their milk when they grow up.
0 comments - Posted May 10, 2007
A teeny weeny new pump, about a quarter the size of existing pumps, is being readied for the market in 2008. Developed by Debiotech, the “Nanopump” will be made of two parts: a permanent part containing the electronics and a disposable skin patch with the reservoir and pumping mechanism.
0 comments - Posted May 10, 2007
Overweight and insulin resistance may contribute to LADA, a form of type 1 diabetes, according to results of a study by Dr. Sofia Carlsson and her fellow researchers from Stockholm.
0 comments - Posted May 7, 2007
If you’re a woman who’s noticed unusually thick and coarse hair on your face and body, you may have polycystic ovarian syndrome (PCOS). It’s the most common cause of excessive hair growth, called hirsuitism in medical terms, in women.
0 comments - Posted May 5, 2007
When it comes to administering insulin, many people prefer an insulin pen over the standard syringe and vial because they find pens more convenient and more accurate. And pre-filled disposable pens are easiest of all, because you don’t have to install a new cartridge when the pen is empty–you just toss it out.
5 comments - Posted May 5, 2007
On March 28, 1950, nine-year-old Betty Adamski Schunke entered the hospital with a diagnosis of type 1 diabetes. She remembers the date vividly. She also remembers the words of her pediatrician, one of the first women in the field: “You can do anything you want to do as long as you remember you have diabetes and plan accordingly.” A feisty, stubborn little girl who strove for perfection and never backed down, she took it for her motto.
0 comments - Posted May 4, 2007
We’ve gotten the results from our women's sex survey, and now the word is out about you, your diabetes, and sex...
0 comments - Posted May 3, 2007
The 21st century may be remembered as the time when diabetes became a worldwide epidemic. However, it may also be known as the time when the disease was cured.
8 comments - Posted May 3, 2007
PHILADELPHIA, April 19, 2007 - Eat right. Exercise. Monitor blood sugar. Take medication regularly. This is the advice physicians give the more than 20 million Americans affected with diabetes. Yet implementation of these recommendations is often far from ideal, putting patients at greater risk for damage to the heart, kidneys, eyes, and feet.
0 comments - Posted May 3, 2007
Last summer our family changed forever when Lauren, our nine-year-old daughter, was diagnosed with type 1 diabetes. A whirlwind of shock, anger, and worry engulfed me as I watched an incurable chronic illness move into our home.
5 comments - Posted May 1, 2007
April 2007
Nick Jonas is a personable boy of fourteen who happens to be a member of the Jonas Brothers Band, a group of three brothers with a devoted following of very passionate young fans. In November 2005, Nick Jonas found out that he had type 1 diabetes.
1466 comments - Posted Apr 27, 2007
At 63 years old, I've coped successfully with insulin-dependent diabetes for 46 years. Education and acceptance are the keys, but it took me years (and the support of loving family and friends) to achieve them.
0 comments - Posted Apr 27, 2007
Constant controversy swirls about which kind of weight-loss diet works best, but there is precious little scientific evidence comparing one diet to another. To provide some real diet data, a recent Journal of the American Medical Association (JAMA) study pitted the Atkins, Zone, LEARN, and Ornish diets against each other in a year-long head-to-head study.
0 comments - Posted Apr 26, 2007
Carbs and carbs alone, not fat, increase body weight. It doesn't matter whether the carbs are from sugar, bread, fruit, or vegetables: They’re all rapidly digested and quickly converted to blood glucose. A short time after a carb-rich meal, the glucose in your bloodstream rises rapidly, and your pancreas produces a large amount of insulin to take the excess glucose out.
26 comments - Posted Apr 24, 2007
Remember the big picture: Populations that stick to traditional high-carbohydrate diets (for example, Asian rice-based diets) typically have low rates of obesity and diabetes. When they abandon traditional rice-based diets in favor of meatier Western fare, carbohydrate intake falls, but weight problems and diabetes increase.
4 comments - Posted Apr 24, 2007
When I developed diabetes in 1946, physicians thought that the high illness and death rate of diabetics was due to dietary fat and the supposedly resultant elevation of serum cholesterol. Since the DCCT trial, the scientific literature overwhelmingly supports the role of elevated blood sugar in all long-term diabetic complications.
2 comments - Posted Apr 24, 2007
A recent Joslin-led study has identified the insulin receptor as an important protein that promotes islet cell growth in mice whose bodies are unable to use insulin properly, or are insulin resistant, a precursor to type 2 diabetes.
0 comments - Posted Apr 23, 2007
Dismal Predictions - In 1949, at the age of 13, I was diagnosed with diabetes. I was told that I would have to take shots for life and that my life would probably last only 25 years longer. Furthermore, I could eat no candy, and all my children would be diabetic.
2 comments - Posted Apr 23, 2007
A lot of new medicines have come out, with a pile of new acronyms: GLP-1, DPP-4, BYOB…well, that last one is probably familiar, but a little background on the other two might not be out of place. You’re going to be seeing a lot more of them in the future, and it’ll help to be on speaking terms.
1 comment - Posted Apr 20, 2007
The FDA has approved Janumet, Merck’s merge of metformin and Januvia into one pill, for use with type 2 diabetes in the United States. Januvia (sitagliptin) is a DPP-4 inhibitor that works by enhancing the incretin system, a natural process that lowers blood sugar.
7 comments - Posted Apr 20, 2007
Milpitas, CA, March 30, 2007 – LifeScan, Inc., maker of OneTouch® Brand Blood Glucose Monitoring Systems, is offering customers that own one of several models of OneTouch Brand Systems a no-charge meter upgrade to one of the company's latest, most innovative meters.(1)
0 comments - Posted Apr 20, 2007
If you have type 1 diabetes and feel like the rest of the world doesn’t have an inkling about your disease, you’re right. According to a nationwide survey, nearly eighty percent of Americans don’t know the difference between type 1 and type 2 diabetes.
0 comments - Posted Apr 20, 2007
The story of Doug Burns’ arrest during a low blood sugar episode has generated a lot of comments from the diabetes community. How did it happen, why did it happen, and how could it have been handled differently?
1 comment - Posted Apr 19, 2007
About three million people in the United States have type 1 diabetes, yet there are fewer than 300,000 insulin pumpers. Given the highly touted data in favor of insulin pumping, we want to know your reasons for either going or not going on the pump. So we've posted a survey here where you can reveal why a pump is, or is not, for you. Your attitudes are important to us, and to all of you, because real change is based on understanding.
4 comments - Posted Apr 19, 2007
Whitehouse Station, N.J., March 26, 2007 – JANUVIA™ (sitagliptin1), Merck & Co., Inc.'s once-a-day oral treatment for patients with type 2 diabetes, has been granted a license from the European Commission. JANUVIA now becomes the first and only medication in a new class of drugs known as dipeptidyl peptidase-4 inhibitors (DPP-4 inhibitors), which enhance the body’s own ability to lower blood sugar when it is elevated, to be adopted by the European Commission.
1 comment - Posted Apr 18, 2007
Animas has just introduced its fifth generation insulin pump, the 2020. Especially for those without 20/20 vision, it comes with a self-illuminating, high contrast color screen that uses Organic Light-Emitting Diode (OLED) technology.
1 comment - Posted Apr 18, 2007
In a February 2007 report in Diabetes Care, researchers found that women with yeast infections get
better results with boric acid suppositories than with the prescription anti-fungal Diflucan (fluconazole).
0 comments - Posted Apr 16, 2007
For people who develop type 1 diabetes, the autoimmune attack on beta cells actually starts up to ten years before diabetes is diagnosed, when autoantibodies first appear in the blood and begin attacking the beta cells.
0 comments - Posted Apr 16, 2007
On January 30, 2007, the FDA upgraded NovoLog (a fast-acting insulin analog from Novo Nordisk) from Category C to Category B, thereby indicating that NovoLog is safe and effective for pregnant women with type 1 and their unborn children.
0 comments - Posted Apr 16, 2007
A December 2006 review of clinical studies on chromium picolinate, published in Diabetes Technology & Therapeutics, confirmed that chromium picolinate improves blood glucose control and lipid levels in people with type 2 diabetes.
0 comments - Posted Apr 15, 2007
Are you a lefty? Then be sure to read your OptiClik pen right side up, advises the Institute for Safe Medication Practices.
0 comments - Posted Apr 14, 2007
If you have to be fat, it’s a far, far better thing to be fat in places other than your belly. Visceral fat, the kind deep inside the abdomen that inextricably surrounds internal organs, is an organ in itself, secreting hormones and active molecules, called cytokines, which are bad for your health.
1 comment - Posted Apr 14, 2007
There’s a new pump in town, and it’s part of a whole pumping system. The ACCU-CHEK® Spirit insulin pump system includes not only the pump, but also one of the three ACCU-CHEK® blood glucose monitors, software with a bolus calculator on a Palm PDA or smartphone, and a carrying case.
1 comment - Posted Apr 14, 2007
In December 2006, the injected medication Byetta was approved by the FDA for people with type 2 diabetes who are taking a thiazolidinedione (TZD), but don’t have good control of their blood sugar.
0 comments - Posted Apr 14, 2007
You may have seen a group of senior citizens practicing the slow, rhythmic reaching and deliberate stretching movements known as tai chi. Tai chi is considered a soft style martial art, applied with deep relaxation or "softness" in the musculature. Young or old, sick or healthy, even wheel-chair bound: everyone can take up tai chi. And oddly enough, tai chi’s gentle motions burn more calories than surfing and nearly as many as downhill skiing.
1 comment - Posted Apr 13, 2007
What’s the most important goal for kids and families dealing with diabetes? Learn all you can, and then strive for the best possible blood glucose levels without excessive hypoglycemia. This is a tough goal to attain. Our tools, food, insulin, and monitoring, while the best they have ever been, are still imprecise. And although optimal glucose control is critical for immediate and long-term health, one must always be wary of severe and recurring hypoglycemia.
0 comments - Posted Apr 13, 2007
Anybody who takes insulin shots wishes, at least occasionally, for an insulin pill. Insulin in pill form, unfortunately, doesn’t work because stomach acid very efficiently dissolves any protein that comes its way, and that includes insulin.
0 comments - Posted Apr 13, 2007
Researchers from Sao Paulo in Brazil have announced that in a group of fifteen insulin-requiring, newly-diagnosed patients with type 1 diabetes, stem cell therapy has preserved beta cell function and eliminated the need for insulin for up to 35 months so far.
5 comments - Posted Apr 12, 2007
Ten years ago, Michael Helyer, a New Zealand man with type 1 diabetes for eighteen years, received a transplant of pig islets. Much to the surprise of researchers, the pig cells are still putting out insulin at this late date. In fact, it was Mr. Helyer who alerted scientists at Living Cell Technologies (LCT) that the cells were still functioning.
2 comments - Posted Apr 12, 2007
Like a fish on a fragile line, handling teenagers requires a delicate touch. My teenage son Danny has type 1 diabetes, and I’ve learned that when he overlooks important aspects of his self-care, it’s paramount not to let the lines of communication break. Sometimes calm restraint is the best option, as a recent incident demonstrates.
0 comments - Posted Apr 12, 2007
Dr. Bernhard Hering of the University of Minnesota is recognized the world over as the premier expert on pancreatic islet transplants. He sees islet transplantation as the best hope for the cure of type 1 diabetes, and his optimism is supported by his research.
0 comments - Posted Apr 11, 2007
If you don’t know what diabetes is, I’ll explain to you what it is. Hi, my name is Erin. I’m eight years old, and I have diabetes. I can tell you what I have to do every day to keep myself healthy. Now I have to check my blood sugar four times a day, every day. And I also have to take shots. No, it’s not fun, but I have to.
0 comments - Posted Apr 11, 2007
Six years ago, Julie DeFruscio’s two-year-old daughter was diagnosed with type 1 diabetes. Two years later, her 13-year-old son was also diagnosed with type 1. And four months after that, her ten-year-old son diagnosed himself with diabetes - unfortunately, he was right.
0 comments - Posted Apr 11, 2007
In 1997, Minnesota became the first of a handful of states to pass a law requiring drug makers to disclose payments made to doctors. Its records reveal that over twenty percent of the state’s physicians have received such payments, generally for giving speeches about drugs to other doctors.
0 comments - Posted Apr 10, 2007
A study published in the December 2006 issue of The American Journal of Clinical Nutrition showed that high fructose consumption doesn’t raise insulin resistance or ectopic lipid deposition (fat in the wrong place) in healthy lean young males, but does heighten risk of cardiovascular disease by increasing plasma triglycerides.
0 comments - Posted Apr 9, 2007
Half of Fifty 50’s profits are donated to research seeking a diabetes cure that, once found, will put Fifty 50 out of business. Its a novel business plan, funding your own demise, but it works for Gary Russell, the companys president and one of its three founders, along with John Beers and Patricia Gawdun. Since the company debuted its first product in 1991, its given away over ten million dollars to diabetes research.
0 comments - Posted Apr 7, 2007
It’s already clear that people with type 2 diabetes are more susceptible to periodontal disease than people without diabetes. Now researchers at the University of Copenhagen School of Dentistry have found that periodontal disease may contribute to pre-diabetes, at least in rats.
0 comments - Posted Apr 6, 2007
Have you lost interest in the world around you? Are you more difficult to engage in conversation or in doing chores? Have you lost interest in doing things or in starting new activities? Are you apathetic or indifferent? If your answer to these questions is yes, then you may be suffering from apathy syndrome.
1 comment - Posted Apr 5, 2007
Actress Delta Burke, best known for her role as the zaftig Susanne Sugerbaker in the television show Designing Women, is the new spokeswoman for the Byetta Let’s Talk campaign, sponsored by Amylin Pharmaceuticals, Inc. and Eli Lilly and Company. She’s a Byetta user herself who has lost twenty pounds while on the medication.
0 comments - Posted Apr 4, 2007
Ask yourself: Do I know someone who consistently reaches for a donut over oatmeal, has a standing date with their TV instead of the gym or prefers high-calorie, high-fat fast food to healthy meals? If you answered yes, you may know someone who has type 2 diabetes or is at high risk for developing it.
1 comment - Posted Apr 4, 2007
Here are some useful tips to help you choose a meter that’s right for you - and continue to use it successfully.
0 comments - Posted Apr 3, 2007
Dr. David Reiss had never heard of diabetes until age 16, when he found out he had type 1 during his college physical exam. He rebelled and refused injections for a year, but by then there were ketones in his urine and he had no choice. That was 42 years ago, when people gave themselves just one injection a day.
0 comments - Posted Apr 2, 2007
March 2007
The day after my eleventh Easter, I was diagnosed with Type 1 diabetes. I got a shot that very night, and at least two shots every day for the next fifteen years, until I went on the pump. It seems appropriate that on the day the disease took over my body, a fire took over the chimney of our house.
0 comments - Posted Mar 29, 2007
Q: Please describe your background.
Morey Haymond: A pediatric endocrinologist by training, I have been involved in
metabolic studies of kids, infants, and adults for 35 years. I work with children who have disorders of
carbohydrate metabolism, including diabetes and hypoglycemia. Understanding the regulation of those
processes has been a focus of my research, and I have looked at amino acid and fat metabolism as well.
1 comment - Posted Mar 29, 2007
Are you among the six million Americans who have type 2 diabetes and don’t realize it? Take heed: March 27 is the 19th Annual Diabetes Alert Day, sponsored by the American Diabetes Association as a wake-up call to people who are completely in the dark about the fact that they are living with diabetes.
0 comments - Posted Mar 27, 2007
Q: Are there any long-term side effects of the popular drugs to treat type 2 diabetes?
2 comments - Posted Mar 24, 2007
Boston - March 5, 2007 - Over the past several years, Joslin Investigator Mary R. Loeken, Ph.D., and her colleagues at Joslin Diabetes Center have unlocked several mysteries behind what puts women with diabetes more at risk of having a child with birth defects.
0 comments - Posted Mar 21, 2007
All is not well with Boomer Wells, the 43-year-old pitcher for the San Diego Padres who found out two weeks ago that he has type 2 diabetes. A large man, 6 feet, 4 inches tall and 250 pounds, with a BMI of 30, he’s technically obese. But he says that he’s already making changes that will control the disease by eliminating rice, pasta, potatoes, white bread, and fast food from his diet. He’s also cut out alcohol (except for a glass of wine now and then so that he can “still run with the guys.”)
0 comments - Posted Mar 21, 2007
Neal Brenner, 41 of Roanoke, Virginia is embarking on the journey of a lifetime which began on March 8 and lasts until March 24. With nothing but a laptop, a satellite phone, and his insulin pump to manage his diabetes, Neal will drive over 4,800 miles through the Arctic Circle with a friend as they take part in a 16-day adventure from Edmonton and ending in Tuktoyaktuk (the uppermost edge of Canada’s Northwest Territories).
0 comments - Posted Mar 20, 2007
Valley Forge, Pa. - Good Neighbor Pharmacy®, a 25 year old network of independently owned pharmacies with over 2,700 locations nationwide, is proud to be the “Official Medical Supply” sponsor of the 2007 Ironman 70.3 California and seven other Ironman events.
0 comments - Posted Mar 20, 2007
Lilly has launched Memoir, a sleek reusable insulin pen that looks like a classy Mont Blanc writing pen instead of a medical tool. The first insulin pen with a memory, it allows users to record and review their last 16 insulin doses, including the priming doses and the time of delivery. It uses Humalog and is available by prescription.
0 comments - Posted Mar 17, 2007
A 24-week study compared the effectiveness and safety of Galvus (vildagliptin), a DPP-4 inhibitor, with Avandia (rosiglitazone), a thiazolidinedione, in a double-blind, randomized, controlled, multi-center study. Both drugs had similar effects on A1c’s: Galvus reduced A1c by 1.1 %, and Avandia reduced A1c by 1. 3%. Most notably, patients did not gain weight with Galvus, but gained an average of 3.4 pounds with Avandia.
0 comments - Posted Mar 16, 2007
Compared to the volumes of research lavished on the development of useful medicines, there is not much study devoted to whether people actually take that medicine or not. Obviously, the best medicine in the world doesn’t do any good if it’s not taken. And according to evidence presented at American Heart Association 2006 Scientific Sessions, people just aren’t taking their medicine like they should.
0 comments - Posted Mar 15, 2007
New York, New York - March 12, 2007 - About 1,000 people attending the Diabetes Research Institute’s Carnival for a Cure fundraising event in New York yesterday were treated to a live concert by the young pop rock band, the Jonas Brothers, and some surprising inspiration from one of the band members.
123 comments - Posted Mar 13, 2007
Approximately a million people a day look to the Internet for answers about diabetes. Now Diabetes Health, a long-time leader in patient advocacy through Diabetes Health magazine, has launched the best site on the web for finding those answers.
0 comments - Posted Mar 9, 2007
BOSTON - March 1, 2007 - A new study from Joslin Diabetes Center may shed light on why some people can eat excessive amounts of food and not gain weight or develop type 2 diabetes, while others are more likely to develop obesity and this most common form of diabetes on any diet.
0 comments - Posted Mar 7, 2007
Are ketones a healthy or an unhealthy sign?
Ketones in the urine can be a danger sign if your blood sugar is too
high and insulin levels are too low. It can indicate acidosis, an
abnormal condition usually occurring in people with out of control
type 1 diabetes requiring immediate medical attention. Ketones can
also occur because of other metabolic conditions.
0 comments - Posted Mar 1, 2007
February 2007
BOSTON - Feb. 27, 2007 - It is widely recognized that the teenage years are often a challenging time for youth with diabetes to maintain good blood glucose control. Hormonal changes, peer pressure, food temptations, and resistance to following good health practices are among the factors that make it difficult for many youngsters. Unfortunately, poor diabetes control places youth at increased risk of developing complications from diabetes later in life.
0 comments - Posted Feb 28, 2007
MINNEAPOLIS, Minn. - For the millions of people worldwide who are afflicted with diabetes, we are now one step closer to a potential cure for the disease. Spring Point Project, a non-profit organization created to expedite the widespread availability of islet tissue for diabetes care, will open its first biosecure animal facility in Western Wisconsin in February to hold high-health pathogen-free pigs. Insulin-producing islet cells from pigs are needed to meet the demands that cannot be realized by using transplantation of human islets.
0 comments - Posted Feb 28, 2007
On October 10, 2006, Roche Diagnostics announced the launch of the first ACCU-CHEK branded insulin pump—the ACCU-CHEK Spirit insulin pump system.
1 comment - Posted Feb 28, 2007
PRINCETON, N.J. - January 25, 2007 - Former President Bill Clinton will be the keynote speaker at the Global Changing Diabetes Leadership Forum, taking place on March 13, 2007 in New York City hosted by Novo Nordisk and supported by the International Diabetes Federation.
5 comments - Posted Feb 28, 2007
Six people are about to receive pig islet transplantations for the first time, as a New Zealand company called Living Cell Technologies (LCT) begins a year-long Phase I/IIA clinical trial in Moscow, Russia.
1 comment - Posted Feb 22, 2007
On January 27, in Phoenix, Arizona, ten-year-old Andrew gave up his beloved miniature horse, Zig Zag, to raise money for the Juvenile Diabetes Research Foundation (JDRF). He had to think about it hard; they’d been together since he was six. But he swallowed his sorrow and donated his pony to the JDRF’s gala auction because he believed “Zig Zag could help find a cure.”
0 comments - Posted Feb 14, 2007
Brian MacLeod, 47, is arguably the best blind golfer in North America. Reigning king of the U.S. Blind Open and four-time defending Canadian champion, he’s shot as low as 83 and is on track to be the best in the world. But it’s been a long haul to the fairway for MacLeod.
0 comments - Posted Feb 7, 2007
I was diagnosed with type 1 diabetes at 11 months old, and I have struggled for almost 46 years to keep control of it. With diabetes, you never get a break.
0 comments - Posted Feb 1, 2007
Data presented at the November 2006 Diabetes Technology Meeting in Atlanta, Georgia, found that the Contour Blood Glucose Meter from Bayer accurately detects hypoglycemia.
1 comment - Posted Feb 1, 2007
On November 6, 2006, Bayer HealthCare issued a news release that addressed the issue of miscoded blood glucose meters.
0 comments - Posted Feb 1, 2007
The latest and greatest skins are a great way for youngsters to express themselves and show off their cell phones and MP3 players. Now Medtronic MiniMed is offering skins for its Paradigm insulin pump.
1 comment - Posted Feb 1, 2007
Researchers in New York are saying that insulin pump therapy at the time of type 1 diagnosis “provides a positive experience … with excellent clinical outcomes and apparent prolongation of the honeymoon period.”
0 comments - Posted Feb 1, 2007
Roche Diagnostics recently announced the launch of the first ACCU-CHEK branded insulin pump—the ACCU-CHEK Spirit insulin pump system.
0 comments - Posted Feb 1, 2007
Data presented at the October 2006 Annual Scientific Meeting of NAASO, The Obesity Society, found that 60 milligrams of orlistat (Xenical), in conjunction with a reduced-calorie diet, provided significantly greater reductions in LDL cholesterol and weight when compared to treatment with a placebo and a reduced-calorie diet.
0 comments - Posted Feb 1, 2007
The addition of niacin to existing medical regimens for patients with heart disease and well-controlled LDL levels improves inflammatory markers, according to researchers at Tufts-New England Medical Center in Boston, Massachusetts.
0 comments - Posted Feb 1, 2007
In September 2006, Walmart Corporation announced a new prescription drug program that will offer a list of 291 generic drugs selling for $4 for a 30-day supply.
0 comments - Posted Feb 1, 2007
According to Reuters Health, a study appearing in the October 2006 issue of European Heart Journal found that people with diabetes who have suffered a heart attack or episode of severe angina benefit just as much from treatment with statins as those without diabetes.
0 comments - Posted Feb 1, 2007
Asian researchers say there is an increased risk of vitamin B12 deficiency associated with metformin use.
0 comments - Posted Feb 1, 2007
Oral-lyn, a new insulin spray made by Generex Biotechnology Corporation, has received the 2006 Technology Award for Innovation in the field of diabetic therapies from Frost and Sullivan, a market research company.
0 comments - Posted Feb 1, 2007
A particular regimen Dutch researchers call the GAME regimen provides long-term BG control with less weight gain.
0 comments - Posted Feb 1, 2007
Patients with high blood pressure and type 2 diabetes benefit from taking an angiotensin-convertingenzyme (ACE) inhibitor to lower blood pressure—even if they have no evidence of kidney or heart disease.
0 comments - Posted Feb 1, 2007
Novartis reports that there will be a three-month delay in approval for its experimental diabetes drug, Galvus, due to the FDA’s request for additional safety data.
0 comments - Posted Feb 1, 2007
“Among persons with impaired fasting glucose levels or impaired glucose tolerance, the use of ramipril [Altace] for three years does not significantly reduce the incidence of diabetes or death.”
0 comments - Posted Feb 1, 2007
Zinc plays a role in the synthesis and action of insulin in the body. Insulin, obviously, plays a critical role in diabetes. But does zinc, then, play a critical role in diabetes prevention? There’s no evidence of that, according to a review of the scientific literature published in January 2007 by the Cochrane Library, which found nothing to suggest that zinc supplementation is useful in the prevention of type 2 diabetes.
0 comments - Posted Feb 1, 2007
UK researchers says that breastfeeding in infancy is associated with “a reduced risk of type 2 diabetes, with marginally lower insulin concentrations in later life, and with lower blood glucose and serum insulin concentrations in infancy.”
0 comments - Posted Feb 1, 2007
A study published in the August/September 2006 edition of Angiology shows that Pycnogenol significantly reduced diabetic microangiopathy in patients.
0 comments - Posted Feb 1, 2007
U.K researchers say that twice-daily injection of insulin glargine (Lantus) helps to alleviate blood glucose rises in the late afternoon and drops toward the end of a 24-hour period that are frequently seen in type 1s who inject Lantus once daily with a meal-time fast-acting insulin.
0 comments - Posted Feb 1, 2007
Novocell, Inc., a San Diego, California-based stem cell engineering company, announced on October 19, 2006, the development of a process that “efficiently converts human embryonic stem cells into insulin-producing pancreatic endocrine cells.”
0 comments - Posted Feb 1, 2007
Despite successfully restoring insulin production and blood-glucose stability after transplantation, insulin independence is usually not sustainable after the Edmonton Protocol.
0 comments - Posted Feb 1, 2007
It’s not easy to navigate the crowded waters of type 2 oral medications. There are dozens of them, and their names have a lot in common with tongue twisters. They’re hard to pronounce, and harder to remember. But they’re necessary. Of the 20 million Americans with diabetes, 90 to 95 percent have type 2. Although some people with diabetes are able to manage their condition through diet and exercise alone, the majority cannot control their blood sugar without medication. According to the CDC, among adults diagnosed with diabetes, 57% take oral medication; 16% take insulin; 12% take both insulin and oral medication; and only 15% take neither insulin nor oral medication.
0 comments - Posted Feb 1, 2007
As a type 1 interested in nature’s ability to heal, I ask, What is causing this so-called diabetes epidemic? Why is it expanding from Western countries to developing countries at the same rate that fast food and junk food are spreading?
2 comments - Posted Feb 1, 2007
You might know me as the publisher of Diabetes Health. I’m also a mother of two, the daughter of a woman who died of type 2 diabetes, and a theater buff. But from now on, I hope you’ll come to know me as someone who brings important stories to you every issue, stories about people who are making a difference in diabetes.
0 comments - Posted Feb 1, 2007
The Banting farm, a pilgrimage site for people with diabetes all over the world, is slated for the bulldozer.
0 comments - Posted Feb 1, 2007
We’ve made big strides on our new Web site since I last wrote to you, and it’s shaping up into an exciting and dynamic community gathering place. Once it’s been inaugurated, you’ll want to drop in on a daily basis and check out what’s happened since the day before. We’re going to be posting all our articles hot off the press, and the input from you will be right there as well, ready for the lively back-and-forth that already animates your letters to the editor.
0 comments - Posted Feb 1, 2007
Although most research about the effect of diabetes on sex has focused on men, some studies report that women are at higher risk for sexual dysfunction than diabetic men. It’s high time that the woman’s side of the story was given the attention that it deserves.
1 comment - Posted Feb 1, 2007
January 2007
The conventional wisdom that autoimmune dysfunction is solely responsible for type 1 diabetes may go up in smoke after the discovery by Canadian researchers that abnormal nerve endings are critical in the cause and cure of type 1 diabetes in mice. In the December 15 issue of Cell, Dr. Michael Dosch and his team reported that eliminating malfunctioning sensory nerve cells in the pancreas of NOD mice (Non-Obese Diabetic mice, genetically predestined to develop diabetes) prevented the disease; equally surprising, inserting a protein produced by healthy nerve cells into already diabetic mice cured them of diabetes within a single day.
0 comments - Posted Jan 25, 2007
It was supposed to be a simple test: I’d pee in a cup, listen to my doctor’s suggestions to feel better, and go home with a prescription. Except on that day, it wasn’t that simple. I sat in the exam room and waited for my doctor to return. When he finally did and started to talk, saying that he suspected diabetes, I remember seeing my mom’s face fall.
0 comments - Posted Jan 17, 2007
December 2006
University of Pittsburgh researchers say that moderate weight loss improves arterial stiffness in people with type 2 diabetes.
0 comments - Posted Dec 1, 2006
On October 17, 2006, the oral medication Januvia (sitagliptin phosphate) was granted approval by the FDA. Januvia is the first diabetes treatment approved in a new class of drugs known as DDP-4 inhibitors that enhances the body’s own ability to lower elevated blood sugar.
0 comments - Posted Dec 1, 2006
“Discontinuing basal insulin during exercise is an effective strategy for reducing hypoglycemia in children with type 1 diabetes,” say researchers from Tampa, Florida, “but the risk of hyperglycemia is increased.”
0 comments - Posted Dec 1, 2006
Eli Lilly and Co. has announced its LillyforLife Achievement Award Winners, who are honored for their outstanding personal and professional achievements in diabetes.
0 comments - Posted Dec 1, 2006
The new ezManager Plus from Animas Corporation is an upgrade from the older ezManager product, and adds the ability to download information from the Animas IR1000/1200 insulin pumps and numerous blood glucose meters. The ezManager Plus is actually two programs— one for a PDA and one that runs on Windows-based PCs. The Palm OS (PDA) application lets you count carbohydrates, calculate insulin dosages (carbohydrate dosages, too) and log meals, insulin, blood glucose and activity.
2 comments - Posted Dec 1, 2006
In November 2006, Insulet Corporation, maker of the OmniPod Insulin Management System, announced that it had won a Nixon Peabody/Smith & Nephew Medical Device Innovation Award from the Massachusetts Medical Device Industry Council (MassMEDIC).
0 comments - Posted Dec 1, 2006
A few pump users have noted some odd occurrences in the day-to-day management of their insulin pump. Skin problems are a real concern and, sometimes, a puzzle to solve.
0 comments - Posted Dec 1, 2006
Biggest Gripe Is That There Will Never Be a Cure
0 comments - Posted Dec 1, 2006
As any fan of the mega-hit television show American Idol knows, making it through the first stage of auditions is not easy. Contestants wait in line for up to 12 hours to get the chance to sing a few bars before the discerning ears of judges Randy Jackson, Paula Abdul and Simon Cowell.
3 comments - Posted Dec 1, 2006
Adam Morrison, 22, is an NBA star that also has type 1 diabetes. He does not, however, have a horror story about his type 1 diagnosis that makes his ascension to NBA stardom seem like an “in-your-face” to an endocrinologist’s pessimistic predictions.
2 comments - Posted Dec 1, 2006
November 2006
When Pittsburgh Steelers’ offensive lineman Kendall Simmons won the 2002 Joe Greene Great Performance Award for being the Steelers “Rookie of the Year,” he felt at the top of his game.
0 comments - Posted Nov 27, 2006
In honor of National Diabetes Month, we welcome you to Diabetes Health’s “Best-Of” issue.
0 comments - Posted Nov 1, 2006
This month in our Meters and Pumps & Infusion Sets sections we are doing something a little different. Diabetes Health is launching Diabetes Health TV from our homepage (www.diabeteshealth.com).
1 comment - Posted Nov 1, 2006
The idea for this article came to me one night after attending a diabetes support group at a local hospital. During the meeting, the discussion of serious complications became so graphic that there was an air of melancholy and hopelessness permeating the entire room. I thought, "What we really need is the good news." I tried to imagine whether I would miss any part of having diabetes if I could be cured today.
2 comments - Posted Nov 1, 2006
Like so many others, Kris Berg, EdD, an exercise physiologist at the University of Nebraska at Omaha, has observed the rapid-fire increase in obesity that has recently been labeled an “epidemic.”
0 comments - Posted Nov 1, 2006
October 2006
I wish to raise awareness about and concern for dental problems that might be complicated by the new Exubera therapy and other therapies employing the dry powder inhaler (DPI) technology as a means of administering therapeutic medications.
0 comments - Posted Oct 1, 2006
Let’s be realistic. Many children look forward all year long to Halloween, and Halloween usually means bags full of sugary candy. But Halloween can still be enjoyed by children with diabetes if parents help monitor their snacking. With some planning, Halloween treats do not need to cause havoc with your child’s blood glucose control.
0 comments - Posted Oct 1, 2006
Chromium picolinate supplementation in type 2s already taking sulfonylureas significantly improves insulin sensitivity and glucose control. In addition, it also improves body weight when compared with a placebo group.
0 comments - Posted Oct 1, 2006
A common misunderstanding regarding the metabolic effects of low-carbohydrate diets concerns the formation of ketone bodies. The presence of ketones caused by fat burning is often confused with ketoacidosis resulting from uncontrolled diabetes, starvation or certain alcoholic conditions.
0 comments - Posted Oct 1, 2006
Diabetes and school make a difficult combination. Dealing with temporary basal rates, tests (for both BGs and academics), lunch, recess, and so on can all throw a student’s diabetes management a major-league curve.
0 comments - Posted Oct 1, 2006
Going low during exercise can be frightening. Preventing low blood glucose involves two strategies: decreasing insulin dosage or increasing carbohydrate intake. Sounds simple, but in reality it takes time for each individual to find the right combination that works for him or her.
0 comments - Posted Oct 1, 2006
Rezulin, the first thiazolidinedione drug, was withdrawn from the market in 2000. Just three years earlier, the FDA had approved Rezulin through a “fast track” approval process, marking January 1997 as the beginning of a new era in type 2 diabetes management by helping type 2s make use of their own insulin more effectively.
0 comments - Posted Oct 1, 2006
September 2006
Walking to Work Decreases Type 2 Risk Japanese researchers say that the duration of a walk to work is associated with a decreased risk of incidence of type 2 diabetes in Japanese men.
0 comments - Posted Sep 1, 2006
Real-Time Pump and CGMS Technology Given the Go-Ahead by the FDA
0 comments - Posted Sep 1, 2006
Reducing Inner Body Fat Is the Key to Metabolic Improvement After Weight Loss
0 comments - Posted Sep 1, 2006
On June 22, 2006, Generex Biotechnology announced it had signed an agreement with Cardinal Health to manufacture clinical trial batches of Generex Oral-lyn, an inhalable insulin spray that is already available in the country of Ecuador.
0 comments - Posted Sep 1, 2006
As I get older, I get more calls from friends and family members telling me about their recent diabetes diagnosis. A little over a year ago, my first cousin Jeannie called to announce her inclusion in the growing type 2 club.
0 comments - Posted Sep 1, 2006
As little as 15 years ago, drinking fluids during sports practice or exercise was considered a sign of weakness. In fact, water was often withheld from athletes as punishment or as an attempt to make them “tough.”
2 comments - Posted Sep 1, 2006
What are your expectations when it comes to pump training? Are they realistic? Do you want improved blood glucose control, improved health and flexibility in choosing when and what to eat? Or, do you just want to avoid frequent intensive insulin injections? Are you a “set it and forget it” type?
0 comments - Posted Sep 1, 2006
Fresh from the ADA Scientific Sessions in Washington, D.C., we present over 30 diabetes studies from scientists around the world.
0 comments - Posted Sep 1, 2006
Ron Mason was a workaholic. He spent six, sometimes seven days a week crafting and installing high-quality cabinets and furniture in and around Santa Cruz, California, where he owned and managed a small, homegrown woodworking business. Mason, who describes his product as “high-end, low-volume,” said that for a number of years, putting in a 70-hour workweek was not atypical—it was merely life as usual.
2 comments - Posted Sep 1, 2006
Weight-Loss Books Dr. Bernstein’s Diabetes Solution: The Complete Guide to Achieving Normal Blood Sugars, by Richard K. Bernstein, MD (Little Brown, 2003)
0 comments - Posted Sep 1, 2006
August 2006
Byetta, which came on the market last year, was developed to help people with type 2 diabetes who weren’t getting adequate blood glucose control using other drugs. Any associated weight loss was only incidental.
16 comments - Posted Aug 1, 2006
For many years, we have been told that an artificial pancreas is several years away. After the May 16 Juvenile Diabetes Research Foundation’s Artificial Pancreas Forum, that message hasn’t changed.
0 comments - Posted Aug 1, 2006
One of the common criticisms of the lower-carb lifestyle is that it doesn’t provide adequate nutrition. Is this really true?
0 comments - Posted Aug 1, 2006
Hypertension (high blood pressure) affects about 50 million individuals in the United States and about 1 billion worldwide. It is the most common diagnosis, associated with 35 million office visits and a risk factor for heart disease, stroke and renal failure.
0 comments - Posted Aug 1, 2006
As a user of LifeScan glucose meters, I was eager to take a look at their diabetes management software. I installed the software, hooked up the data cable, grabbed my trusty UltraSmart glucose meter and started up the software with a double-click on the OneTouch icon.
8 comments - Posted Aug 1, 2006
Continuing last month’s “What’s New” theme, we offer you a rundown of the latest and greatest in insulin pumping. Below are some highlights of developments to keep your eyes on.
0 comments - Posted Aug 1, 2006
Medtronic MiniMed has linked an insulin pump with a continuous glucose monitor. Approved by the U.S. Food and Drug Administration in April, the pump part of the combination is already available. The company expects the monitor component to be available by the end of August.
0 comments - Posted Aug 1, 2006
Stevia is a bush native to South America that has been used for centuries by the natives of Paraguay, where it’s grown primarily as a sweetener and for medicinal uses. The stevia leaf is usually a component of Paraguayan teas, including the widely popular beverage yerba mate.
3 comments - Posted Aug 1, 2006
1. How do these oral hypoglycemic agents (OHAs) work?
0 comments - Posted Aug 1, 2006
I am always willing to discuss diabetes with anyone who is interested. And since I openly perform my blood glucose tests and administer insulin shots in public, it is fair to say that many people around me do become interested.
0 comments - Posted Aug 1, 2006
July 2006
I just discovered your May 2005 article, “Why Did the JDRF Try to Discredit Cure Research?” That, and lingering resentment over my own futile correspondence with Van Etten and Ahearn, inspired me to dig deeper into some points you made and some reasonable suspicions your article aroused.
0 comments - Posted Jul 1, 2006
Novo Nordisk announced that Levemir is now commercially available in the United States.
0 comments - Posted Jul 1, 2006
Eli Lilly and Co. has launched a new premixed insulin, Humalog Mix50/50 (50 percent insulin lispro protamine suspension, 50 percent insulin lispro injection of rDNA origin).
0 comments - Posted Jul 1, 2006
Langham Engineering has announced the release of the Vial Vase. Invented by J. Michael Langham, a diabetic for 30 years, Vial Vase is designed to keep insulin vials upright, secure and organized in the refrigerator, on the countertop or anywhere insulin is stored.
0 comments - Posted Jul 1, 2006
The FDA has informed Medtronic, Inc., that it was approving its MiniMed Paradigm Real-Time Insulin Pump and Continuous Glucose Monitoring System.
0 comments - Posted Jul 1, 2006
A long-term study published in a recent issue of the Journal of Palliative Medicine found that Eli Lilly’s non-narcotic prescription drug Cymbalta (duloxetine HCl) is as safe and well-tolerated as current routine care that uses one or more medications for the management of pain caused by diabetic nerve damage. Study findings also show that Cymbalta did not adversely affect the progression of diabetes or many of the complications associated with the illness, such as damage to the nerves, kidneys and eyes.
0 comments - Posted Jul 1, 2006
On April 20, 2006, Eli Lilly & Co. told Diabetes Health that the U.S. Food and Drug Administration has granted priority review status for Arxxant, its potential “first-in-class treatment” for diabetic retinopathy.
0 comments - Posted Jul 1, 2006
GlaxoSmithKline announced the availability of Avandaryl (rosiglitazone maleate and glimepiride), a new fixed-dose combination product for type 2 diabetes.
0 comments - Posted Jul 1, 2006
According to a January 5, 2006, posting on its Web site (www.fda.gov), GlaxoSmithKline and the FDA have notified healthcare professionals about post-marketing reports of new-onset and worsening diabetic macular edema for patients receiving Avandia.
0 comments - Posted Jul 1, 2006
Pump Expeditions from Medtronic MiniMed is a CD-ROM-based program that offers users both entertainment and education.
1 comment - Posted Jul 1, 2006
Jane complains of a burning pain at the abdominal insertion site as soon as the cannula is inserted. It doesn’t subside, so she removes the set and re-inserts at a new location.
1 comment - Posted Jul 1, 2006
Years ago it was common for women to indulge their food cravings during pregnancy, and usually without ill effect. Now it is vital that women of childbearing age understand the importance of good nutrition before pregnancy and how to decrease their risk of diabetes during pregnancy.
0 comments - Posted Jul 1, 2006
Summer is synonymous with travel; family vacations, reunions, weddings, you name it. It seems like we all find some reason to hit the road during the summer months.
0 comments - Posted Jul 1, 2006
David Kliff is the editor of The Diabetic Investor. In 1994 he was diagnosed with type 2.
1 comment - Posted Jul 1, 2006
For basketball fans, the 1973 New York Knicks are the stuff of legend. That year, not only did they compile a record of 57 wins and 25 losses en route to becoming NBA champions, but they also boasted a starting lineup of players all of whom are now members of the NBA Hall of Fame.
0 comments - Posted Jul 1, 2006
This may well go down in history as the Year of the Meter. Not since Tom Clemens patented the first blood glucose meter in 1971 have we seen such significant advances.
0 comments - Posted Jul 1, 2006
As David Mendosa points out in his feature article this month, ‘The Year of the Meter,’ 2006 is barely more than half over and we have already an abundance of new blood glucose meters. Well, it’s not only meters that are in abundance this year, but other diabetes drugs, devices and technologies as well. So much so, that there haven’t been enough pages in Diabetes Health to cover all of the new products.
0 comments - Posted Jul 1, 2006
June 2006
Eli Lilly and Co. has announced a call for entries for the 2006 LillyforLife Awards.
0 comments - Posted Jun 1, 2006
In recent history, can you think of a more popular television show than “American Idol”?
0 comments - Posted Jun 1, 2006
Problems with blood glucose control need to be prevented and solved when using an insulin pump. When something goes wrong, do you blame it on the pump or suspect you made an error? Do you assume there is a pump problem with each alarm?
0 comments - Posted Jun 1, 2006
Are you unable to tear your child away from the computer? Do you want your child to learn more about diabetes? “Type 1 Diabetes in Children: A Passport to Knowledge,” from Savvy Knowledge Systems, may be your solution.
0 comments - Posted Jun 1, 2006
In 1998, Eli Lilly & Co.’s rapid-acting insulin analogue lispro (Humalog) appeared on the U.S. market, followed in 2000 by Novo Nordisk’s rapid-acting counterpart aspart (NovoLog). Joined now by sanofi-aventis’ glulisine (Apidra), these rapid-acting insulins offer both convenience and improved blood glucose control to people who require bolus insulin.
1 comment - Posted Jun 1, 2006
May 2006
By October of this year, Merck & Co., Inc., expects the FDA to rule on its novel type 2 drug Januvia (sitagliptin phosphate). On February 15, 2006, the FDA accepted Merck’s New Drug Application (NDA) for Januvia for standard review.
0 comments - Posted May 1, 2006
The continuous glucose sensors of today that will in time lead to development of an artificial pancreas are getting a tremendous boost from the Juvenile Diabetes Research Foundation International (JDRF). The boost is the organization’s commitment of up to $6.5 million dollars this year and next.
0 comments - Posted May 1, 2006
On February 28, 2006, sanofi-aventis announced that its fast-acting Apidra (insulin glulisine [rDNA origin] injection) is now available by prescription in the United States. Apidra was granted FDA approval in April 2004.
1 comment - Posted May 1, 2006
A study published in the February 2006 issue of the Journal of Nutrition says that chromium prompts muscles to become more efficient.
0 comments - Posted May 1, 2006
My life depends entirely on getting little squirts of insulin into my bloodstream on a regular basis. Too little, and high blood glucose hijacks my moods—tired and cranky are the watchwords here. Too much insulin makes my BGs plummet—and shakiness and confusion take over until I eat something containing sugar.
3 comments - Posted May 1, 2006
Choosing the right insulin pump and infusion set can be a daunting task for prospective users, and the number of options available may be overwhelming.
0 comments - Posted May 1, 2006
Who says the low-carb lifestyle is dead? You would never believe that after spending a weekend with experts in the field.
1 comment - Posted May 1, 2006
When retired NBA center Chris Dudley was diagnosed with type 1 diabetes in 1981, the high school sophomore’s first concern was whether he would be able to continue playing sports.
0 comments - Posted May 1, 2006
April 2006
What would you tell endocrinologists and primary care physicians (PCPs) about Avandia (rosiglitazone maleate), Avandamet (rosiglitazone maleate and metformin HCl) and Avandaryl (rosiglizatone maleate and glimepiride) as treatment options for diabetics?
0 comments - Posted Apr 1, 2006
Why are today’s insulin syringes and pen needles better than ever?
0 comments - Posted Apr 1, 2006
With the new basal-bolus insulin landscape, what is the most important thing that endocrinologists and primary care physicians need to know so that their insulin-using patients can follow the best possible regimen?
0 comments - Posted Apr 1, 2006
John H. Holcombe, MD, is a clinical associate professor of pediatrics at the Indiana University School of Medicine and medical fellow, diabetes, for Eli Lilly and Co.
0 comments - Posted Apr 1, 2006
If you are an endocrinologist or primary care physician who works with diabetics, you have undoubtedly heard of the insulin pen. You probably know of their popularity in Europe or have heard testimonials from pen users about their ease of use.
0 comments - Posted Apr 1, 2006
For diabetes patients who inject insulin through a syringe, the people at Becton-Dickinson (BD) say that they should always know exactly which brand, dose capacity and needle size to use and why.
0 comments - Posted Apr 1, 2006
An interview with Alan Marcus, MD, FACP, the global medical director at Medtronic Diabetes
0 comments - Posted Apr 1, 2006
Mary is a 64-year-old woman who has been diagnosed with type 2 diabetes for 14 years. She is obese at 220 pounds. Mary has been treated with a sulfonylurea (a medication that stimulates the pancreas to secrete insulin, such as glypizide and glyburide) for the past 10 years. Her glucose control for the past three or four years has not been good. A recent A1C was 9.5% (normal range is 4% to 6%, with a goal of 7%). Metformin (Glucophage) and rosiglitazone (Avandia) were added to her sulfonylurea. Both her pre-meal and post-meal glucose values improved and her A1C came down to 7.8%. However, her fasting blood glucose levels were in the upper 100 mg/dl to low 200 mg/dl range. She was afraid of “the needle” and did not want to start on insulin. In addition, Mary was recently diagnosed with early diabetic eye disease (retinopathy) and nerve disease (neuropathy).
0 comments - Posted Apr 1, 2006
Several months ago, I met Sophia, a woman in her mid-40s who had been struggling to manage her type 2 diabetes for years. Her blood glucose levels were typically well above 300 mg/dl, and she had an equally high A1C of 12.5%. She made it clear that the last thing she wanted was insulin.
0 comments - Posted Apr 1, 2006
At age 25, Dee was initially diagnosed with gestational diabetes in 1972. After giving birth, she was diagnosed with type 1 diabetes. Insulin was started with a daily injection of morning NPH and progressed to twice-daily doses. Dee did not have good control with either regimen.
0 comments - Posted Apr 1, 2006
Lois Jovanovic, MD, is currently the CEO & chief scientific officer at The Sansum Diabetes Research Institute along with being an adjunct professor of Bimolecular Science and Engineering at The University of California-Santa Barbara and a clinical professor of medicine at The University of Southern California-Keck School of Medicine. Dr. Jovanovic has devoted her career to diabetes and diabetes-related research. Her expertise is in intensified insulin delivery, continuous glucose monitoring and the creation of an artificial beta-cell system. Her favorite research projects are in the field of diabetes and pregnancy—both type 1 diabetic pregnant women and gestational diabetic woman.
0 comments - Posted Apr 1, 2006
Diabetics who visit a diabetes care specialist have better A1Cs than those who visit a primary care physician.
0 comments - Posted Apr 1, 2006
Although they are equally effective when it comes to delivering insulin, more insulin-using patients expressed a preference to continue using an insulin pen after trying one.
0 comments - Posted Apr 1, 2006
Because people with diabetes sometimes suffer from visual impairment as well as reduced manual dexterity, Japanese researchers assessed the reliability of dose selection and setting of five insulin devices by patients using auditory and sensory confirmation.
0 comments - Posted Apr 1, 2006
Researchers at the Diabetes Research Institute at the University of Miami Miller School of Medicine wrote a paper discussing the heart-protective properties of thiazolidinediones (TZDs) such as Avandia and Actos.
0 comments - Posted Apr 1, 2006
Adding the sulfonylurea glimepiride (Amaryl) to insulin therapy results in “sustained improvement of glycemic control in patients with poorly controlled type 2 diabetes,” according to researchers at the department of endocrinology and metabolism at Kyoto Prefectural University of Medicine.
0 comments - Posted Apr 1, 2006
C-reactive protein (CRP) is an inflammation marker that can be an underlying cause of a host of metabolic conditions, among them insulin resistance, metabolic syndrome and diabetes. CRP, according to researchers at the State University of New York Health Sciences Center, also has been shown to be a strong independent predictor of vascular events.
0 comments - Posted Apr 1, 2006
New Zealand researchers say that in clinical trials of people with type 2 diabetes, Actos as stand-alone therapy or in combination with metformin, repaglinide, insulin or a sulphonylurea induced “both long- and short-term improvements in [blood glucose] control and serum lipid profiles.”
0 comments - Posted Apr 1, 2006
A group of Buffalo, NY, researchers recommend that patients with uncontrolled type 2 diabetes who take extremely high doses of insulin give the insulin pump a try.
0 comments - Posted Apr 1, 2006
Pump therapy in preschool children, according to researchers at Texas Children’s Hospital, is “feasible and safe.”
0 comments - Posted Apr 1, 2006
Spanish researchers claim that in most studies of small children with diabetes, insulin pump therapy resulted in improved A1Cs and a decreased rate of hypoglycemia without an abnormal increase in body mass index (BMI) and without adversely affecting psychosocial outcomes in young people with type 1.
0 comments - Posted Apr 1, 2006
A majority of diabetes patients cannot accurately estimate their blood glucose levels, leading researchers to suggest that home testing is a necessary part of diabetes self-care.
0 comments - Posted Apr 1, 2006
Compared with other basal insulins, French researchers suggest that insulin detemir (Levemir) may offer a “better reproducibility.” In addition, it may also reduce the risk of hypoglycemia and lead patients to titrate their insulin doses more easily.
0 comments - Posted Apr 1, 2006
For people with type 2, Lantus in combination with oral medications can be a cost-equivalent alternative to conventional insulin therapy.
0 comments - Posted Apr 1, 2006
In three comparative randomized trials, researchers at the department of medicine at Baylor College of Medicine in Houston, Texas, demonstrated that type 2s who used premixed insulins were more likely to reach blood glucose goals than those using only Lantus once daily.
0 comments - Posted Apr 1, 2006
Nonalcoholic fatty liver disease (NAFLD) is significantly associated with a moderately increased cardiovascular disease risk among type 2s, according to Italian researchers.
0 comments - Posted Apr 1, 2006
A recent study compared the effect of adding exenatide (Byetta) or insulin glargine (Lantus) to type 2 patients’ treatment regimens. The type 2s previously had been taking metformin and a sulfonylurea with little success.
0 comments - Posted Apr 1, 2006
Having diabetes, especially type 1, puts you at an increased risk for all non-vertebral fractures—in particular, hip fractures.
0 comments - Posted Apr 1, 2006
Transplant experts at the Section of Transplantation in the University of Chicago Department of Surgery say that an artificial pancreas has promising potential as an approach to preventing or reversing complications associated with diabetes.
0 comments - Posted Apr 1, 2006
In 1998, Eli Lilly & Co.’s rapid-acting insulin analogue lispro (Humalog) appeared on the U.S. market, followed in 2000 by Novo Nordisk’s rapid-acting counterpart aspart (NovoLog). Joined now by sanofi-aventis’ glulisine (Apidra), these rapid-acting insulins offer both convenience and improved blood glucose control to your patients who require bolus insulin.
0 comments - Posted Apr 1, 2006
Recent developments in the treatment of diabetes mellitus have shown that “tight” control and intensive therapy are necessary to prevent complications, increased morbidity and mortality. We are all familiar with the findings of the DCCT and various UKPDS studies and sub-studies. The importance of these “landmark” studies does not need any further discussion at this time.
2 comments - Posted Apr 1, 2006
On January 7, 2006, I gave birth to a beautiful baby girl named Ava Grace Baker. She was 8.4 pounds and 20.25 inches long. It took 30 hours, but it was worth every moment. Well, almost every moment.
7 comments - Posted Apr 1, 2006
Some things I remember very clearly. Like the moment the doctor told me that I had to take injections for the rest of my life. This news bothered me horribly. But what if he had told me I could inhale the insulin instead? I would have been on cloud nine.
0 comments - Posted Apr 1, 2006
Ernest had high triglycerides and his blood glucose was rising. He thought he was doing all right, so you can imagine what he thought when I recommended that he increase the amount of fat and protein in his diet and decrease his carbohydrate intake.
0 comments - Posted Apr 1, 2006
As I discussed in the February 2006 issue, the Atkins Nutritional Approach has four phases, ranging from the most restrictive Induction phase to the Lifetime Maintenance phase.
0 comments - Posted Apr 1, 2006
Abbott Diabetes Care is already looking beyond continuous sensing. More than two years ago it asked the U.S. Food and Drug Administration to approve its FreeStyle Navigator Continuous Glucose Monitor; that application is still pending.
1 comment - Posted Apr 1, 2006
Pramlintide (Symlin) is a synthetic amylin analogue. First described in 1987, amylin is a neuroendocrine hormone produced by beta cells, which also produce insulin. This hormone is absent in type 1 diabetes and decreased in type 2 diabetes.
0 comments - Posted Apr 1, 2006
While people with diabetes know that they face a long list of possible complications, it looks as if there’s one more to worry about: We now know that diabetics also face a higher risk of colon cancer. However, there is some consolation in knowing that colon cancer can often be prevented with proper testing.
0 comments - Posted Apr 1, 2006
When it’s time to restock your diabetes medications and supplies, have you ever wished that you didn’t have to make that trip to the pharmacy? Wouldn’t you like to avoid the lines, the traffic or parking hassles, and having to find your prescription for the refill?
2 comments - Posted Apr 1, 2006
If you have ever dreamed of taking your insulin without needles, your dream came true on January 27, 2006. That was when the U.S. Food and Drug Administration (FDA) approved Exubera (insulin of human [rDNA origin]) Inhalation Powder for treatment of adults with type 1 and type 2 diabetes.
0 comments - Posted Apr 1, 2006
March 2006
Have you ever thought, “No one understands me or my problems”? You felt alone. You felt overwhelmed. You struggled intensely.
0 comments - Posted Mar 1, 2006
On January 27, 2006, Pfizer Inc. received word from the FDA that its inhalable insulin Exubera was granted approval. It is the first inhaled form of insulin and the first insulin option that does not need to be administered by injection in the United States.
0 comments - Posted Mar 1, 2006
The Juvenile Diabetes Research Foundation (JDRF) announced that a series of five clinical trials “may hold groundbreaking clues that would alter the course of type 1 diabetes.”
0 comments - Posted Mar 1, 2006
Fetal and neonatal exposure to nicotine may increase a child’s risk of becoming obese and developing type 2 diabetes later in life.
0 comments - Posted Mar 1, 2006
People are constantly being told that the only way to lose weight or maintain a healthy weight is to control calorie intake. It does not matter so much where the calories come from as long as one is eating less and burning more. Is this true? It is to some extent, but not completely.
1 comment - Posted Mar 1, 2006
